Medical thoracoscopy combined with intrapleural injection of urokinase for treatment of pleural infection-a multicenter, prospective, randomized controlled study: study protocol.

Authors: Wang, Kaige^1,2 (AUTHOR) youjiangbuyi@163.com, Yang, Linhui^1,2 (AUTHOR) yanglinhuififi@163.com, Tian, Panwen^1,2 (AUTHOR) mrascend@163.com, Tan, Fen³ (AUTHOR) tanfen2007@csu.edu.cn, Liu, Dan^1,2 (AUTHOR) liudan10965@wchscu.cn, Li, Weimin^1,2 (AUTHOR) weimi003@yahoo.com

Source: Respiratory Research. 1/18/2025, Vol. 26 Issue 1, p1-7. 7p.

Subject Terms: *MEDICAL sciences, *UROKINASE, *CLINICAL trials, *CHEST tubes, *MEDICAL drainage

Urokinase in the treatment of tuberculous pleurisy: a systematic review and meta-analysis.

Authors: Jing, Wenyao¹ (AUTHOR), Weng, Ruolan¹ (AUTHOR), Lin, Ping¹ (AUTHOR), Luo, Miao¹ (AUTHOR) luomiaodoctor@qq.com

Source: BMC Infectious Diseases. 2/24/2024, Vol. 24 Issue 1, p1-17. 17p.

Subject Terms: *UROKINASE, *PLEURAL effusions, *TUBERCULOSIS, *PLEURISY, *RANDOMIZED controlled trials

Minimally Invasive Technique for Spontaneous Intraparenchymal Hemorrhage.

Authors: Raval, Himanshu¹ (AUTHOR) hims02929@gmail.com, Shah, Kalpesh¹ (AUTHOR), Bhatt, Mona² (AUTHOR)

Source: Indian Journal of Neurosurgery. 2024, Vol. 13 Issue 2, p176-178. 3p.

Subject Terms: *UROKINASE, *FEEDING tubes, *HEMIPARESIS, *HYPERTENSION, *HEMATOMA

Redrawing Urokinase Receptor (uPAR) Signaling with Cancer Driver Genes for Exploring Possible Anti-Cancer Targets and Drugs.

Authors: Chang, Yu-Ching¹ (AUTHOR) yc.chang112917@gmail.com, Wu, Chung-Ze^2,3 (AUTHOR) chungze@tmu.edu.tw, Cheng, Chao-Wen^4,5 (AUTHOR) ccheng@tmu.edu.tw, Chen, Jin-Shuen^6,7 (AUTHOR) dgschen@vghks.gov.tw, Chang, Li-Chien^1,8 (AUTHOR) dgschen@vghks.gov.tw

Source: Pharmaceuticals (14248247). Oct2023, Vol. 16 Issue 10, p1435. 18p.

Subject Terms: *CANCER genes, *UROKINASE, *ANTINEOPLASTIC agents, *GENE ontology, *GENE regulatory networks

RGD peptide modified RBC membrane functionalized biomimetic nanoparticles for thrombolytic therapy.

Authors: Xu, Zichen¹, Huang, Jinxia², Zhang, Tao², Xu, Wenfeng², Liao, Xiaoling², Wang, Yi³, wangyi@cqmu.edu.cn, Wang, Guixue¹, wanggx@cqu.edu.cn

Source: Journal of Materials Science: Materials in Medicine; Apr2023, Vol. 34 Issue 4, p1-12, 12p

Poly- α , β - d , l -Aspartyl-Arg-Gly-Asp-Ser-Based Urokinase Nanoparticles for Thrombolysis Therapy.

Authors: Chen, Shuangling¹ (AUTHOR), Liang, Meng¹ (AUTHOR), Wu, Chengli¹ (AUTHOR), Zhang, Xiaoyi¹ (AUTHOR), Wang, Yuji¹ (AUTHOR) wangyuji@ccmu.edu.cn, Zhao, Ming¹ (AUTHOR) wangyuji@ccmu.edu.cn

Source: Molecules. Mar2023, Vol. 28 Issue 6, p2578. 15p.

Subject Terms: *UROKINASE, *INTRACRANIAL hemorrhage, *FIBRINOLYTIC agents, *THROMBOLYTIC therapy, *NANOPARTICLES, *FIBRIN

Geographic Terms: UNITED Kingdom

Prevention of Dialysis Catheter Malfunction with Urokinase and Heparin: A Randomized, Controlled Trial.

Authors: Quan Wang¹, Nan Jiang¹, Weidong Chen¹, Li Cheng¹, Shuai Fu¹, Qiang Li¹, Hongbo Li¹ wq6395661@163.com

Source: Alternative Therapies in Health & Medicine. Oct2024, Vol. 30 Issue 10, p218-224. 7p.

Subject Terms: *DIALYSIS catheters, *UROKINASE, *HEPARIN, *HEMODIALYSIS, *BACTEREMIA

Generation and Characterization of Novel Pan‐Cancer Anti‐uPAR Fluorescent Nanobodies as Tools for Image‐Guided Surgery.

Authors: Mateusiak, Łukasz¹, Lukasz.Mateusiak@vub.be, Floru, Sam¹, De Groof, Timo W. M.¹, Wouters, Janne¹, Declerck, Noemi B.¹, Debie, Pieterjan¹, Janssen, Simone^1,2, Zeven, Katty¹, Puttemans, Janik¹, Vincke, Cécile^3,4, Breckpot, Karine⁵, Devoogdt, Nick¹, Hernot, Sophie¹, Sophie.Hernot@vub.be

Source: Advanced Science; 8/14/2024, Vol. 11 Issue 30, p1-11, 11p

Ultrasound and Intrapleural Enzymatic Therapy for Complicated Pleural Effusion: A Case Series with a Literature Review.

Authors: Inchingolo, Riccardo¹ (AUTHOR) riccardo.inchingolo@policlinicogemelli.it, Ielo, Simone² (AUTHOR) simone.ielo01@icatt.it, Barone, Roberto² (AUTHOR) roberto.barone01@icatt.it, Whalen, Matteo Bernard² (AUTHOR) matteo.whalen01@icatt.it, Carriera, Lorenzo² (AUTHOR) lorenzo.carriera01@icatt.it, Smargiassi, Andrea¹ (AUTHOR) andrea.smargiassi@policlinicogemelli.it, Sorino, Claudio³ (AUTHOR) claudio.sorino@uninsubria.it, Lococo, Filippo⁴ (AUTHOR) filippo.lococo@policlinicogemelli.it, Feller-Kopman, David⁵ (AUTHOR) david.j.feller-kopman@hitchcock.org

Source: Journal of Clinical Medicine. Aug2024, Vol. 13 Issue 15, p4346. 18p.

Subject Terms: *PLASMIN, *UROKINASE, *EMPYEMA, *PLASMINOGEN, *PLEURAL effusions

Urokinase System in Pathogenesis of Pulmonary Fibrosis: A Hidden Threat of COVID-19.

Authors: Shmakova, Anna A.^1,2 (AUTHOR), Popov, Vladimir S.² (AUTHOR), Romanov, Iliya P.² (AUTHOR), Khabibullin, Nikita R.² (AUTHOR), Sabitova, Nailya R.² (AUTHOR), Karpukhina, Anna A.³ (AUTHOR), Kozhevnikova, Yana A.² (AUTHOR), Kurilina, Ella V.¹ (AUTHOR), Tsokolaeva, Zoya I.¹ (AUTHOR), Klimovich, Polina S.^1,2 (AUTHOR), Rubina, Kseniya A.² (AUTHOR), Vassetzky, Yegor S.³ (AUTHOR), Semina, Ekaterina V.^1,2 (AUTHOR) e-semina@yandex.ru

Source: International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 2, p1382. 26p.

Subject Terms: *PULMONARY fibrosis, *UROKINASE, *PLASMINOGEN activators, *CD14 antigen, *MYOFIBROBLASTS, *COVID-19, *INTRAVENOUS injections, *CADHERINS

Prognostic significance of the urokinase plasminogen activator system in tissue and serum of dogs with appendicular osteosarcoma.

Authors: Matsuyama, Arata¹ (AUTHOR), Wood, Geoffrey A.² (AUTHOR), Speare, Rachael² (AUTHOR), Schott, Courtney R.² (AUTHOR), Mutsaers, Anthony J.^1,3 (AUTHOR) mutsaers@uoguelph.ca

Source: PLoS ONE. 9/29/2022, Vol. 17 Issue 9, p1-20. 20p.

Subject Terms: *TISSUE plasminogen activator, *UROKINASE, *OSTEOSARCOMA, *PROGRESSION-free survival, *PLASMINOGEN, *PLASMIN, *PLASMINOGEN activators

The role of soluble urokinase plasminogen activator receptor (suPAR) in patients with cancer: a review of the current literature.

Authors: Paraskevas, Themistoklis¹, Mulita, Francesk² oknarfmulita@hotmail.com, Michailides, Christos¹, Verras, Georgios-Ioannis², Liolis, Elias³, Oikonomou, Eleousa¹, Perdikaris, Ioannis², Perdikaris, Panagiotis², Bouchagier, Konstantinos², Panagiotopoulos, Ioannis⁴, Kasartzian, Dimitrios-Ioannis⁵, Filis, Dimitrios², Tchabashvili, Levan², Spyropoulou, Despoina⁶, Velissaris, Dimitrios¹

Source: Medicinski Glasnik. Aug2022, Vol. 19 Issue 2, p197-206. 10p.

Subject Terms: *PLASMINOGEN activators, *UROKINASE, *CANCER patients, *PROGNOSTIC tests

Comparison of the Mortality Prediction Value of Soluble Urokinase Plasminogen Activator Receptor (suPAR) in COVID-19 and Sepsis.

Authors: Vassiliou, Alice G.¹ (AUTHOR) alvass75@gmail.com, Zacharis, Alexandros¹ (AUTHOR), Vrettou, Charikleia S.¹ (AUTHOR) alexandroszacharis5@gmail.com, Keskinidou, Chrysi¹ (AUTHOR), Jahaj, Edison¹ (AUTHOR), Mastora, Zafeiria¹ (AUTHOR), Orfanos, Stylianos E.¹ (AUTHOR), Dimopoulou, Ioanna¹ (AUTHOR), Kotanidou, Anastasia¹ (AUTHOR) alvass75@gmail.com

Source: Diagnostics (2075-4418). May2022, Vol. 12 Issue 5, pN.PAG-N.PAG. 8p.

Subject Terms: *PLASMINOGEN activators, *UROKINASE, *SEPSIS, *COVID-19, *PROGNOSIS

Observation on the clinical efficacy of external ventricular drain combined with intraventricular urokinase injection and intravenous piracetam in the treatment of intraventricular hemorrhage.

Authors: Jing Cui¹, Xin-lei Ma¹, Jian-zhou Tong¹, Min Shu¹ kqccyuo6682682@163.com

Source: Pakistan Journal of Medical Sciences. May/Jun2022, Vol. 38 Issue 5, p1292-1297. 6p.

Subject Terms: *INTRAVENOUS injections, *UROKINASE, *INTRAVENTRICULAR hemorrhage, *PIRACETAM, *DRUG side effects, *MEDICAL device removal

Geographic Terms: CHINA

Urokinase Plasminogen Activator Receptor: An Important Focal Player in Chronic Subdural Hematoma?

Authors: Jensen, Thorbjørn Søren Rønn¹ (AUTHOR) tjens07@gmail.com, Olsen, Markus Harboe^2,3 (AUTHOR), Lelkaitis, Giedrius⁴ (AUTHOR), Kjaer, Andreas⁵ (AUTHOR), Binderup, Tina⁵ (AUTHOR), Fugleholm, Kåre¹ (AUTHOR)

Source: Inflammation. Jun2024, Vol. 47 Issue 3, p1015-1027. 13p.

Subject Terms: *PLASMINOGEN activators, *UROKINASE, *DURA mater, *SUBDURAL hematoma, *HEMATOMA

Urokinase Plasminogen Activation System Modulation in Transformed Cell Lines.

Authors: Culej Bošnjak, Diana¹ (AUTHOR) diana.culej2010@gmail.com, Balent, Tihana¹ (AUTHOR) petra.korac@biol.pmf.hr, Korać, Petra¹ (AUTHOR) mmatulic@biol.pmf.hr, Antica, Mariastefania² (AUTHOR) antica@irb.hr, Matulić, Maja¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p675. 14p.

Subject Terms: *PLASMINOGEN activators, *PLASMINOGEN activator inhibitors, *UROKINASE, *WESTERN immunoblotting, *HUMAN cloning, *PLASMINOGEN, *PLASMIN

Utilization of Prognostic Biomarker Soluble Urokinase Plasminogen Activator Receptor in the Emergency Department: A Tool for Safe and More Efficient Decision-making.

Authors: Holstein, Ria M¹ (AUTHOR) ria.holstein@helsinki.fi, Mäkinen, Marja T¹ (AUTHOR), Castrén, Maaret K¹ (AUTHOR), Kaartinen, Johanna M¹ (AUTHOR)

Source: Biomarker Insights. 3/9/2022, Vol. 17, p1-7. 7p.

Subject Terms: *PLASMINOGEN activators, *UROKINASE, *HOSPITAL emergency services, *BIOMARKERS, *OLDER people, *PLASMINOGEN

Mechanical Thrombectomy for Large Vessel Occlusion Strokes Involving a Cerebral Aneurysm in the Target Vessel: Case Series.

Authors: Miyazaki, Takeshi, Kori, Ryusuke, Katagiri, Masaya, Inoue, Tomoyuki, Sato, Kota, Sato, Tatsuya, Terasawa, Yuka, Himeno, Takahiro, Espinola-Zavaleta, Nilda

Source: Case Reports in Vascular Medicine; 4/2/2025, Vol. 2025, p1-6, 6p

Subject Terms: INTRACRANIAL aneurysms, STROKE, COMPUTED tomography, UROKINASE, THROMBECTOMY

Case Report: Infection with Streptococcus constellatus manifesting as gelatinous pleural effusion in an HIV-positive patient.

Authors: Yang, Zhongxia, Xiong, Wanyuan, Qian, Zibing, Mao, Xiaorong

Source: Frontiers in Immunology; 2025, p1-4, 4p

Subject Terms: STREPTOCOCCAL diseases, MEDICAL drainage, PLEURAL effusions, UROKINASE, STREPTOCOCCUS

Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke.

Authors: Qu, Dian, Liu, Huanhuan, Wei, Zhongming, Cheng, Yao, Fei, Yutong, Xu, Jinghan, Lv, Xiuyu, Li, Wendi

Source: Frontiers in Neurology; 2025, p1-6, 6p

Subject Terms: STROKE patients, ISCHEMIC stroke, THROMBOLYTIC therapy, UROKINASE, PROPENSITY score matching, ENDOVASCULAR surgery