Targeted degradation of CDK9 potently disrupts the MYC-regulated network

Authors: Toure, Mohammed A. ^{1, 2, 3, 4}, Motoyama, Keisuke ^{1, 3, 4}, Xiang, Yichen ^{1, 2, 3, 4}, Urgiles, Julie ^{1, 4, 5}, Kabinger, Florian ^{1, 3, 4}, Koglin, Ann-Sophie ^{6, 7}, Iyer, Ramya S. ^{6, 7}, Gagnon, Kaitlyn ^{6, 7}, Kumar, Amruth ^{6, 7}, Ojeda, Samuel ^{6, 7}, Harrison, Drew A. ^{6, 7}, Rees, Matthew G. ⁴, Roth, Jennifer A. ⁴, Ott, Christopher J. ^{4, 6, 7}, Schiavoni, Richard ¹, Whittaker, Charles A. ¹, Levine, Stuart S. ^{1, 8}, White, Forest M. ^{1, 2, 3}, Calo, Eliezer ^{1, 9}, Richters, Andre ^{1, 3, 4}, Koehler, Angela N. ^{1, 2, 3, 4, 10, ∗}

Source: In Cell Chemical Biology 17 April 2025 32(4):542-555

Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

Authors: Richters, André, Doyle, Shelby K., Freeman, David B., Lee, Christina, Leifer, Becky S., Jagannathan, Sajjeev, Kabinger, Florian, Koren, Jošt Vrabič, Struntz, Nicholas B., Urgiles, Julie, Stagg, Ryan A., Curtin, Brice H., Chatterjee, Deep, Mathea, Sebastian, Mikochik, Peter J., Hopkins, Tamara D., Gao, Hua, Branch, Jonathan R., Xin, Hong, Westover, Lori, Bignan, Gilles C., Rupnow, Brent A., Karlin, Kristen L., Olson, Calla M., Westbrook, Thomas F., Vacca, Joseph, Wilfong, Chris M., Trotter, B. Wesley, Saffran, Douglas C., Bischofberger, Norbert, Knapp, Stefan, Russo, Joshua W., Hickson, Ian, Bischoff, James R., Gottardis, Marco M., Balk, Steven P., Lin, Charles Y., Pop, Marius S., Koehler, Angela N.

Source: In Cell Chemical Biology 18 February 2021 28(2):134-147

A general 11C-labeling approach enabled by fluoride-mediated desilylation of organosilanes.

Authors: Qu, Wenchao, Hu, Bao, Babich, John W., Waterhouse, Nicole, Dooley, Marybeth, Ponnala, Shashikanth, Urgiles, Julie

Source: Nature Communications; 4/8/2020, Vol. 11 Issue 1, p1-10, 10p

Subject Terms: RADIOISOTOPES, RADIOACTIVE tracers, CARBANIONS, DIAGNOSTIC imaging, FUNCTIONAL groups, POSITRONS

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