Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents

Authors: Céline Tolksdorf, Andrea Seidel, Christian Baume, Eileen Moritz, Karen Saljé, Kathrin Lehmann, Karsten Becker, Ulrike Garscha, Thomas Thiele, Edzard Schwedhelm, Mirjam von Lucadou, Mladen V. Tzvetkov, Stefan Engeli, Gabriele Jedlitschky, Bernhard H. Rauch

Source: Platelets, Vol 35, Iss 1 (2024)

Subject Terms: COVID-19, MRP4, platelet activation, S1P, viral infection, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/0953-7104; https://doaj.org/toc/1369-1635

Access URL: https://doaj.org/article/29ead04519cb4821897fc2cf247ef46a

Synthesis and structure–activity relationships for some novel diflapolin derivatives with benzimidazole subunit

Authors: Lisa Vieider, Eva Zoeller, Erik Romp, Martin Schoenthaler, Victor Hernández-Olmos, Veronika Temml, Thomas Hasenoehrl, Daniela Schuster, Oliver Werz, Ulrike Garscha, Barbara Matuszczak

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1752-1764 (2022)

Subject Terms: Diflapolin, benzimidazoles, soluble epoxide hydrolase (sEH), 5-lipoxygenase activating protein (FLAP), solubility and GI absorption prediction, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/64d4071fa89c41b3835b8c14b9c7eab6

Development of SFC-MS Method for Quantification of Eicosanoids Biosynthesized in Primary Human Blood Cells

Authors: Louis Schmidt, Laura Sophie Burmeister, Andreas Greinacher, Stefanie König, Ulrike Garscha

Source: Metabolites, Vol 12, Iss 12, p 1198 (2022)

Subject Terms: oxylipins, supercritical fluid chromatography, monocytes, neutrophils, platelets, validation, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/12/12/1198; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/d2b7bcf5412f4b3db4fe7e1c0c80cb7f

Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase

Authors: Helmut Pein, Alexia Ville, Simona Pace, Veronika Temml, Ulrike Garscha, Martin Raasch, Khaled Alsabil, Guillaume Viault, Chau-Phi Dinh, David Guilet, Fabiana Troisi, Konstantin Neukirch, Stefanie König, Rosella Bilancia, Birgit Waltenberger, Hermann Stuppner, Maria Wallert, Stefan Lorkowski, Christina Weinigel, Silke Rummler, Marc Birringer, Fiorentina Roviezzo, Lidia Sautebin, Jean-Jacques Helesbeux, Denis Séraphin, Alexander S. Mosig, Daniela Schuster, Antonietta Rossi, Pascal Richomme, Oliver Werz, Andreas Koeberle

Source: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8f5b1e43017943509f14b4b68fe07ec5

Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases

Authors: Ernst H. Oliw, Anneli Wennman, Inga Hoffmann, Ulrike Garscha, Mats Hamberg, Fredrik Jernerén

Source: Journal of Lipid Research, Vol 52, Iss 11, Pp 1995-2004 (2011)

Subject Terms: chiral phase HPLC, cyclooxygenase, enzymology/enzyme mechanisms, fatty acid/oxygenation, linoleate diol synthase, manganese lipoxygenase, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520350896; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/69e875a5b7224c2596e61af10e5b2fb8

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