EASL Schools of Hepatology: Pioneering the flipped classroom model and blended learning in medical education

Authors: Francesco Negro, Mounia Heddad Masson, Ulrich Beuers

Source: JHEP Reports, Vol 7, Iss 1, Pp 101266- (2025)

Subject Terms: hepatology education, flipped classroom, critical thinking, cognitive biases, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924002702; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/70635b86c0334ed383a02693e1aa4058

Incidence and prevalence of primary biliary cholangitis in the Netherlands – A nationwide cohort study

Authors: Rozanne C. de Veer, Maria C.B. van Hooff, Ellen Werner, Ulrich Beuers, Joost P.H. Drenth, Frans J.C. Cuperus, Bart van Hoek, Bart J. Veldt, Michael Klemt-Kropp, Suzanne van Meer, Robert C. Verdonk, Hajo J. Flink, Jan Maarten Vrolijk, Tom J.G. Gevers, Cyriel Y. Ponsioen, Martijn J. ter Borg, Khalida Soufidi, Femke Boersma, Hendrik J.M. de Jonge, Frank H.J. Wolfhagen, L.C. Baak, Susanne L. Onderwater, Jeroen D. van Bergeijk, Paul G. van Putten, Gijs J. de Bruin, Rob P.R. Adang, Maria N. Aparicio-Pages, Wink de Boer, Frank ter Borg, Hanneke van Soest, Harry L.A. Janssen, Bettina E. Hansen, Nicole S. Erler, Adriaan J. van der Meer, Sunje Abraham, Huseyin Aktas, Yasser A. Alderlieste, L. (Bert) C. Baak, Martine A.M.C. Baven-Pronk, A. (Sander) van der Beek, Frank C. Bekkering, Menno Beukema, Kirsten Boonstra, Pieter C.J. ter Borg, Paul J. Bus, Djuna L. Cahen, Marcel Cazemier, Lisette J.H. van Dam, Maaike J. Denters, Ludger S.M. Epping, Philip W. Friederich, Nicole F.M. van Gerven, Sven J. van den Hazel, Maria C. van Hooff, Daphne M. Hotho, Matthias C. Jurgens, J.(Netty) van Kemenade, Marjo J. Kerbert-Dreteler, Ingrid C.A.W. Konings, Sander de Kort, Edith M.M. Kuiper, Johan P.H. Kuyvenhoven, Leendert H. Oterdoom, Janne E. van Rooij, Robert Roomer, Johannes Schmidt-Böhmer, Stephan Schmittgens, Tim C.M.A. Schreuder, Jerome Sint Nicolaas, Stephan H.C. van Stiphout, Hans H.K. Thio, Merel M. Tielemans, Sigrid Vandebosch, J. Marleen de Vree, Elsemieke de Vries, Anne Vrieze, Laurens A. van der Waaij, Ulrike de Wit

Source: JHEP Reports, Vol 6, Iss 8, Pp 101132- (2024)

Subject Terms: Primary biliary cholangitis, Incidence, Prevalence, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924001368; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/b78f3031c746431b9a47676360ed92d8

Diagnostic criteria and long-term outcomes in AIH-PBC variant syndrome under combination therapy

Authors: Anna E.C. Stoelinga, Maaike Biewenga, Joost P.H. Drenth, Xavier Verhelst, Adriaan J.P. van der Meer, Ynto S. de Boer, Gerd Bouma, Elsemieke S. de Vries, Robert C. Verdonk, Aad P. van der Berg, Johannes T. Brouwer, Thomas Vanwolleghem, Wim Lammers, Ulrich Beuers, Arantza Farina Sarasqueta, Joanne Verheij, Tania Roskams, Stijn Crobach, Maarten E. Tushuizen, Bart van Hoek, N.M. van Gerven, U. Beuers, K.J. van Erpecum, J.W. den Ouden, A. Bhalla, J.M. Vrolijk, G.H. Koek, M.M.J. Guichelaar, J.J.M. van Meyel, L.C. Baak, M. Klemt-Kropp, M.A.M.T. Verhagen, J.Ph. Kuijvenhoven, H.M. de Jonge

Source: JHEP Reports, Vol 6, Iss 7, Pp 101088- (2024)

Subject Terms: Variant syndrome, Autoimmune Hepatitis, Primary Biliary Cholangitis, ursodeoxycholic acid, glucocorticoids, immunosuppression, Diseases of the digestive system. Gastroenterology, RC799-869

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Relation: http://www.sciencedirect.com/science/article/pii/S2589555924000922; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/23f6d160421f4af7891cf542a20a6ec4

Corrigendum to: 'Endoscopic duodenal mucosal resurfacing improves glycaemic and hepatic indices in type 2 diabetes: 6-month multicentre results' [JHEP Reports 5 (2019) 101041]

Authors: Annieke C.G. van Baar, Ulrich Beuers, Kari Wong, Rehan Haidry, Guido Costamagna, Alia Hadefi, Jacques Deviere, Soumitra S. Ghosh, Juan Carlos Lopez-Talavera, Leonardo Rodriguez, Manoel P. Galvao Neto, Arun Sanyal, Jacques J.G.H.M. Bergman

Source: JHEP Reports, Vol 6, Iss 6, Pp 101041- (2024)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924000429; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/53dd3cc5411d4749bfcc56b501553ea3

Neurofilament light chain but not glial fibrillary acidic protein is a potential biomarker of overt hepatic encephalopathy in patients with cirrhosis

Authors: Koos de Wit, Diederick J. van Doorn, Bregje Mol, Lonneke A. van Vught, Frederik Nevens, Ulrich Beuers, Cyriel Y. Ponsioen, Charlotte E. Teunissen, R. Bart Takkenberg

Source: Annals of Hepatology, Vol 29, Iss 3, Pp 101496- (2024)

Subject Terms: Neuroproteins, Brain diseases, Liver diseases, Metabolism, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268124002904; https://doaj.org/toc/1665-2681

Access URL: https://doaj.org/article/18d1a803e2de4eecac38e7f2c8774275

Laminin 511-E8, an autoantigen in IgG4-related cholangitis, contributes to cholangiocyte protection

Authors: David C. Trampert, Remco Kersten, Dagmar Tolenaars, Aldo Jongejan, Stan F.J. van de Graaf, Ulrich Beuers

Source: JHEP Reports, Vol 6, Iss 4, Pp 101015- (2024)

Subject Terms: Activated T lymphocytes, Biliary bicarbonate umbrella, Cholangiopathy, Epithelial barrier function, GCDC, Glycochenodeoxycholate, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924000168; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/34909bddea67473eac8e116e50b64353

Intrapancreatic fat deposition is unrelated to liver steatosis in metabolic dysfunction-associated steatotic liver disease

Authors: Anne Linde Mak, Nienke Wassenaar, Anne-Marieke van Dijk, Marian Troelstra, Veera Houttu, Koen van Son, Stan Driessen, Diona Zwirs, Sandra van den Berg-Faay, Elizabeth Shumbayawonda, Jurgen Runge, Michail Doukas, Joanne Verheij, Ulrich Beuers, Max Nieuwdorp, Djuna L. Cahen, Aart Nederveen, Oliver Gurney-Champion, Adriaan Holleboom

Source: JHEP Reports, Vol 6, Iss 3, Pp 100998- (2024)

Subject Terms: fatty pancreas disease, pancreatic steatosis, MASLD, MASH, multiparametric MRI, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923003294; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/8abd0a8eef2a4164b2993111e694fcd8

A multisociety Delphi consensus statement on new fatty liver disease nomenclature

Authors: Mary E. Rinella, Jeffrey V. Lazarus, Vlad Ratziu, Sven M. Francque, Arun J. Sanyal, Fasiha Kanwal, Diana Romero, Manal F. Abdelmalek, Quentin M. Anstee, Juan Pablo Arab, Marco Arrese, Ramon Bataller, Ulrich Beuers, Jerome Boursier, Elisabetta Bugianesi, Christopher D. Byrne, Graciela E. Castro Narro, Abhijit Chowdhury, Helena Cortez-Pinto, Donna R. Cryer, Kenneth Cusi, Mohamed El-Kassas, Samuel Klein, Wayne Eskridge, Jiangao Fan, Samer Gawrieh, Cynthia D. Guy, Stephen A. Harrison, Seung Up Kim, Bart G. Koot, Marko Korenjak, Kris V. Kowdley, Florence Lacaille, Rohit Loomba, Robert Mitchell-Thain, Timothy R. Morgan, Elisabeth E. Powell, Michael Roden, Manuel Romero-Gómez, Marcelo Silva, Shivaram Prasad Singh, Silvia C. Sookoian, C. Wendy Spearman, Dina Tiniakos, Luca Valenti, Miriam B. Vos, Vincent Wai-Sun Wong, Stavra Xanthakos, Yusuf Yilmaz, Zobair Younossi, Ansley Hobbs, Marcela Villota-Rivas, Philip N. Newsome

Source: Annals of Hepatology, Vol 29, Iss 1, Pp 101133- (2024)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268123002375; https://doaj.org/toc/1665-2681

Access URL: https://doaj.org/article/f02c612b79da4aaa8837228f72393227

Combined inhibition of bile salt synthesis and intestinal uptake reduces cholestatic liver damage and colonic bile salts in mice

Authors: Roni F. Kunst, Isabelle Bolt, Rychon D.J. van Dasselaar, Bart A. Nijmeijer, Ulrich Beuers, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf

Source: JHEP Reports, Vol 6, Iss 1, Pp 100917- (2024)

Subject Terms: ASBT, IBAT, Intestine-restricted ASBT inhibitors, OCA, Cilofexor, NGM282, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923002483; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/9b3c1ec91c60416aac41d256534c3c20

Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids

Authors: Remco Kersten, David C. Trampert, Lowiek M. Hubers, Dagmar Tolenaars, Harmjan R. Vos, Stan F. J. van de Graaf, Ulrich Beuers

Source: Frontiers in Immunology, Vol 14 (2024)

Subject Terms: biliary bicarbonate umbrella, cholangiopathy, cholestasis, IgG4-related systemic disease, immune-mediated disease, secretory organs, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1251134/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9a8c0afbbd31453fad841b7992688e02

Treatment With Simvastatin and Rifaximin Restores the Plasma Metabolomic Profile in Patients With Decompensated Cirrhosis

Authors: Elisa Pose, Elsa Solà, Juan J. Lozano, Adrià Juanola, Julia Sidorova, Giacomo Zaccherini, Koos deWit, Frank Uschner, Marta Tonon, Konstantin Kazankov, Cesar Jiménez, Daniela Campion, Laura Napoleone, Ann T. Ma, Marta Carol, Manuel Morales‐Ruiz, Carlo Alessandria, Ulrich Beuers, Paolo Caraceni, Claire Francoz, François Durand, Rajeshwar P. Mookerjee, Jonel Trebicka, Victor Vargas, Salvatore Piano, Hugh Watson, Juan G. Abraldes, Patrick S. Kamath, Mark M. Davis, Pere Ginès, for the investigators of the LIVERHOPE Consortium

Source: Hepatology Communications, Vol 6, Iss 5, Pp 1100-1112 (2022)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/2471-254X

Access URL: https://doaj.org/article/ef91c857b6d7462f9f2e68c608047196

A natural history study of paediatric non-alcoholic fatty liver disease over 10 years

Authors: Laura Draijer, Maaike Voorhoeve, Marian Troelstra, Adriaan Holleboom, Ulrich Beuers, Meeike Kusters, Aart Nederveen, Marc Benninga, Bart Koot

Source: JHEP Reports, Vol 5, Iss 5, Pp 100685- (2023)

Subject Terms: Hepatic steatosis, Children, Outcomes, Progression, Fibrosis, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923000162; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/ca261d9761e84f36924ec1aeaef67b7a

Survey uncovering variations in the management of primary sclerosing cholangitis across Europe

Authors: Johanna Eliasson, Bobby Lo, Christoph Scramm, Olivier Chazouilleres, Trine Folseraas, Ulrich Beuers, Henriette Ytting

Source: JHEP Reports, Vol 4, Iss 11, Pp 100553- (2022)

Subject Terms: Primary sclerosing cholangitis, surveillance, inflammatory bowel disease, cholangiocarcinoma, gallbladder polyp, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555922001252; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/f6f5568762604d63a5713095071616af

Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice

Authors: Roni F. Kunst, Dirk R. de Waart, Frank Wolters, Suzanne Duijst, Esther W. Vogels, Isabelle Bolt, Joanne Verheij, Ulrich Beuers, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf

Source: JHEP Reports, Vol 4, Iss 11, Pp 100573- (2022)

Subject Terms: Apical sodium-dependent bile acid transporter (ASBT), IBAT, NTCP, BSEP, PFIC, Alagille, Diseases of the digestive system. Gastroenterology, RC799-869

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Relation: http://www.sciencedirect.com/science/article/pii/S2589555922001458; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/44bd0d993371444b94902a2e94c0bc06

Reduced spontaneous itch in mouse models of cholestasis

Authors: Jacqueline Langedijk, Ruth Bolier, Dagmar Tolenaars, Lysbeth ten Bloemendaal, Suzanne Duijst, Dirk de Waart, Ulrich Beuers, Piter Bosma, Ronald Oude Elferink

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8a91086451c548c488f3ed16188f6c17

A Quantitative In Vitro Potency Assay for Adeno-Associated Virus Vectors Encoding for the UGT1A1 Transgene

Authors: Sem J. Aronson, Robert S. Bakker, Sascha Moenis, Remco van Dijk, Giulia Bortolussi, Fanny Collaud, Xiaoxia Shi, Suzanne Duijst, Lysbeth ten Bloemendaal, Giuseppe Ronzitti, Andrés F. Muro, Federico Mingozzi, Ulrich Beuers, Piter J. Bosma

Source: Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 250-258 (2020)

Subject Terms: adeno-associated virus, AAV8, potency, quantitative potency assay, bilirubin, Crigler-Najjar syndrome, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050120301248; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/edb7a29586e044c8b082be4c5aa3a2dd

Blue-collar work is a risk factor for developing IgG4-related disease of the biliary tract and pancreas

Authors: Lowiek M. Hubers, Alex R. Schuurman, Jorie Buijs, Nahid Mostafavi, Marco J. Bruno, Roel C.H. Vermeulen, Anke Huss, Henk R. van Buuren, Ulrich Beuers

Source: JHEP Reports, Vol 3, Iss 6, Pp 100385- (2021)

Subject Terms: asbestos, autoimmune pancreatitis, IgG4-related cholangitis, occupational, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555921001610; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/5d67c5c28e984c7a868ebbaea753ddfc

Endoscopic duodenal mucosal resurfacing improves glycaemic and hepatic indices in type 2 diabetes: 6-month multicentre results

Authors: Annieke C.G. van Baar, Ulrich Beuers, Kari Wong, Rehan Haidry, Guido Costamagna, Alia Hafedi, Jacques Deviere, Soumitra S. Ghosh, Juan Carlos Lopez-Talavera, Leonardo Rodriguez, Manoel P. Galvao Neto, Arun Sanyal, Jacques J.G.H.M. Bergman

Source: JHEP Reports, Vol 1, Iss 6, Pp 429-437 (2019)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555919301284; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/a3cea8a588914834a225aaab4b1d2246

Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction

Authors: Tilman Sauerbruch, Martin Hennenberg, Jonel Trebicka, Ulrich Beuers

Source: Frontiers in Physiology, Vol 12 (2021)

Subject Terms: bile acids, liver cirrhosis, portal hypertension, microbiome, vasodilation, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.718783/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/b0949249bca04b03b80597d3a83b26e8

Potent suppression of hydrophobic bile acids by aldafermin, an FGF19 analogue, across metabolic and cholestatic liver diseases

Authors: Arun J. Sanyal, Lei Ling, Ulrich Beuers, Alex M. DePaoli, Hsiao D. Lieu, Stephen A. Harrison, Gideon M. Hirschfield

Source: JHEP Reports, Vol 3, Iss 3, Pp 100255- (2021)

Subject Terms: Non-alcoholic steatohepatitis, Primary sclerosing cholangitis, Fibrogenesis, Fibroblast growth factor, Bile acid synthesis, Pro-C3, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555921000318; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/ccc082e5733f41d1b166976e660a219c