Enhancement of chlorpromazine efficacy in breast cancer treatment by 266 nm laser irradiation.

Authors: Udrea, Ana Maria^1,2,3 (AUTHOR), Staicu, Angela¹ (AUTHOR) angela.staicu@inflpr.ro, Smarandache, Adriana¹ (AUTHOR), Andrei, Ionut Relu¹ (AUTHOR), Badea, Madalina Andreea⁴ (AUTHOR), Avram, Speranta³ (AUTHOR), Pascu, Mihail Lucian^1,5 (AUTHOR), Pirvulescu, Ruxandra Angela⁶ (AUTHOR), Balas, Mihaela⁴ (AUTHOR) mihaela.balas@bio.unibuc.ro

Source: Scientific Reports. 12/5/2024, Vol. 14 Issue 1, p1-16. 16p.

Subject Terms: *DRUG repositioning, *MEDICAL sciences, *BREAST cancer, *FOURIER transform infrared spectroscopy, *MOLECULAR structure

Interaction of anti-inflammatory drug nimesulide with ionic and non-ionic surfactant micelles: Insights from spectral and bioinformatics approach

Authors: Enache, Mirela, Andriesei, Bianca Mihaela, Oancea, Alexandra, Udrea, Ana-Maria, Raducan, Adina, Oancea, Petruta, Avram, Speranța

Source: In Journal of Molecular Liquids 15 December 2023 392 Part 1

Photosensitizers-Loaded Nanocarriers for Enhancement of Photodynamic Therapy in Melanoma Treatment.

Authors: Udrea, Ana Maria^1,2 (AUTHOR) ana.udrea@inflpr.ro, Smarandache, Adriana¹ (AUTHOR) adriana.smarandache@inflpr.ro, Dinache, Andra¹ (AUTHOR) simona.stroescu@inflpr.ro, Mares, Catalina² (AUTHOR) speranta.avram@gmail.com, Nistorescu, Simona¹ (AUTHOR), Avram, Speranta² (AUTHOR), Staicu, Angela¹ (AUTHOR) adriana.smarandache@inflpr.ro

Source: Pharmaceutics. Aug2023, Vol. 15 Issue 8, p2124. 42p.

Subject Terms: *PHOTODYNAMIC therapy, *NANOCARRIERS, *VISIBLE spectra, *REACTIVE oxygen species, *MELANOMA

Laser irradiated phenothiazines: New potential treatment for COVID-19 explored by molecular docking

Authors: Udrea, Ana-Maria, Avram, Speranta, Nistorescu, Simona, Pascu, Mihail-Lucian, Romanitan, Mihaela Oana

Source: In Journal of Photochemistry & Photobiology, B: Biology October 2020 211

Bioinformatics Tools for the Analysis of Active Compounds Identified in Ranunculaceae Species.

Authors: Mareş, Cătălina¹ (AUTHOR) catalina.sogor@bio.unibuc.ro, Udrea, Ana-Maria^2,3 (AUTHOR) ana.udrea@inflpr.ro, Şuţan, Nicoleta Anca⁴ (AUTHOR) anca.sutan@upit.ro, Avram, Speranţa¹ (AUTHOR) speranta.avram@gmail.com

Source: Pharmaceuticals (14248247). Jun2023, Vol. 16 Issue 6, p842. 22p.

Subject Terms: *RANUNCULACEAE, *BIOACTIVE compounds, *ALDOSE reductase, *CARBONIC anhydrase inhibitors, *CARBONIC anhydrase

Natural Compounds Therapeutic Features in Brain Disorders by Experimental, Bioinformatics and Cheminformatics Methods

Authors: Avram, Speranta, Puia, Alin, Udrea, Ana Maria, Mihailescu, Dan, Mernea, Maria, Dinischiotu, Anca, Oancea, Florin, Stiens, Johan

Source: Current medicinal chemistry. 27(1):78-98

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105403513.0x000001&indx=1&recIds=ETOCvdc_100105403513.0x000001

Design, Synthesis and Biopharmacological Profile Evaluation of New 2-((4- Chlorophenoxy)Methyl)-N-(Arylcarbamothioyl)Benzamides with Broad Spectrum Antifungal Activity

Authors: Limban, Carmen, Diţu, Lia M., Măruțescu, Luminița, Missir, Alexandru V., Chifiriuc, Mariana C., Căproiu, Miron T., Morusciag, Laurenţiu, Chiriţă, Cornel, Udrea, Ana-Maria, Nuţă, Diana C., Avram, Speranta

Source: Current organic chemistry. 23(12):1365-1377

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090524518.0x000001&indx=1&recIds=ETOCvdc_100090524518.0x000001

In Silico and Experimental Investigation of the Biological Potential of Some Recently Developed Carprofen Derivatives.

Authors: Dumitrascu, Florea¹ (AUTHOR) fdumitra@yahoo.com, Udrea, Ana-Maria^2,3 (AUTHOR) ana.udrea@inflpr.ro, Caira, Mino R.⁴ (AUTHOR) mino.caira@uct.ac.za, Nuta, Diana Camelia⁵ (AUTHOR) carmen.limban@umfcd.ro, Limban, Carmen⁵ (AUTHOR), Chifiriuc, Mariana Carmen^6,7,8 (AUTHOR) carmen.chifiriuc@bio.unibuc.ro, Popa, Marcela⁶ (AUTHOR) marcela.popa@bio.unibuc.ro, Bleotu, Coralia^2,6,9 (AUTHOR) cbleotu@yahoo.com, Hanganu, Anamaria¹ (AUTHOR) ana.hanganu@cco.ro, Dumitrescu, Denisa¹⁰ (AUTHOR) denisa.dumitrescu2014@gmail.com, Avram, Speranta¹¹ (AUTHOR) speranta.avram@gmail.com

Source: Molecules. May2022, Vol. 27 Issue 9, p2722-2722. 23p.

Subject Terms: *GRAM-negative bacteria, *NUCLEAR magnetic resonance spectroscopy, *ENTEROCOCCUS faecalis, *HELA cells, *ACETIC acid, *GRAM-positive bacteria

Chapter 24 - Aryl hydrocarbon receptors and their ligands in human health management

Authors: Udrea, Ana-Maria ¹, Sogor, Catalina ², Buiu, Catalin ³, Avram, Speranta ²

Source: In QSAR in Safety Evaluation and Risk Assessment 2024:329-338

COMPUTATIONAL APPROACHES OF NEW PERSPECTIVES IN THE TREATMENT OF DEPRESSION DURING PREGNANCY

Authors: Udrea, Ana-Maria, Puia, Alin, Shaposhnikov, Sergey, Avram, Speranţa

Source: Farmacia. 66(4):680-687

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN617622763&indx=1&recIds=ETOCRN617622763

Aneuploidy-Inducing Mutations in Mitotic Checkpoint Protein hMad1-Carboxi Terminal Domain Analyzed by SAR and Computational Mutagenesis

Authors: Avram, Speranta, Alexandrescu, Iulia, Puia, Alin, Udrea, Ana Maria, Mernea, Maria, Mihailescu, Dan Florin, Borcan, Livia-Cristina

Source: Current proteomics. 14(4):254-260

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100077920398.0x000001&indx=1&recIds=ETOCvdc_100077920398.0x000001

Repurposing anti-inflammatory drugs for fighting planktonic and biofilm growth. New carbazole derivatives based on the NSAID carprofen: synthesis, in silico and in vitro bioevaluation.

Authors: Dumitrascu, Florea, Caira, Mino R., Avram, Speranta, Buiu, Catalin, Udrea, Ana Maria, Vlad, Ilinca Margareta, Zarafu, Irina, Ioniţă, Petre, Nuţă, Diana Camelia, Popa, Marcela, Chifiriuc, Mariana-Carmen, Limban, Carmen

Source: Frontiers in Cellular & Infection Microbiology; 2023, p1-16, 16p

Subject Terms: CARBAZOLE derivatives, ANTI-inflammatory agents, NONSTEROIDAL anti-inflammatory agents, CARBAZOLE, DRUG repositioning, OXIDANT status

N-Substituted (Hexahydro)-1 H -isoindole-1,3(2 H)-dione Derivatives: New Insights into Synthesis and Characterization.

Authors: Bădiceanu, Carmellina Daniela, Mares, Catalina, Nuță, Diana Camelia, Avram, Speranța, Drăghici, Constantin, Udrea, Ana-Maria, Zarafu, Irina, Chiriță, Cornel, Hovaneț, Marilena Viorica, Limban, Carmen

Source: Processes; Jun2023, Vol. 11 Issue 6, p1616, 13p

Subject Terms: ACETAMIDE, ACETAMIDE derivatives, PHTHALIC anhydride, NUCLEAR magnetic resonance, INTESTINAL absorption, CHEMICAL structure, DRUG target

Photodynamic Activity of TMPyP4/TiO 2 Complex under Blue Light in Human Melanoma Cells: Potential for Cancer-Selective Therapy.

Authors: Balas, Mihaela, Nistorescu, Simona, Badea, Madalina Andreea, Dinischiotu, Anca, Boni, Mihai, Dinache, Andra, Smarandache, Adriana, Udrea, Ana-Maria, Prepelita, Petronela, Staicu, Angela

Source: Pharmaceutics; Apr2023, Vol. 15 Issue 4, p1194, 22p

Subject Terms: BLUE light, PHOTODYNAMIC therapy, REACTIVE oxygen species, FOURIER transform infrared spectroscopy, MELANOMA, BRAF genes, PHOSPHORESCENCE

List of contributors

Authors: Akortia, Eric, Alla, Sai Radha Mani, Alves, Vinicius M., Andrade, Carolina H., Avram, Speranta, Bao, Tong, Benfenati, Emilio, Braga, Rodolpho C., Buiu, Catalin, Chakravarti, Suman K., Chen, Jingwen, Chen, Minjun, Ciura, Krzesimir, Colombo, Erika, Cross, Kevin P., Cui, Shixuan, del Giudice, Giusy, Dong, Fan, Duchowicz, Pablo R., Egbi, Courage, Egodawatta, Prasanna, Elakkiya, Elango, Federico, Antonio, Fratello, Michele, Fu, Zhiqiang, Furuhama, Ayako, Gao, Yuchen, Garro Martinez, Juan C., Gbeddy, Gustav, Giner, Beatriz, Glover, Eric, Goonetilleke, Ashantha, Greco, Dario, Gromelski, Maciej, Gu, Yaxin, Gui, Binxin, Guo, Jing, Guo, Wenjing, He, Jiale, He, Minghui, Hong, Huixiao, Honma, Masamitsu, Huang, Shuheng, Huang, Ruili, Huang, Meiling, Jaeger, Martin, Jillella, Gopala Krishna, Johnson, Candice, Kasamatsu, Toshio, Khan, Pathan Mohsin, Koster, Sander, Kusko, Rebecca, Lee, Myeongsang, Li, Chao, Li, Fei, Li, Bohao, Li, Menglong, Li, Dongying, Li, Jinjie, Li, Xuehua, Li, Zoe, Liao, Tsung-Jen, Liu, Yuan, Liu, Huihui, Liu, Jie, Liu, Wenjia, Lomba, Laura, Lou, Chaofeng, Ma, Guangcai, Manganelli, Serena, Mei, Hu, Mendonca, Sabrina S., Mizuno, Tadahaya, Myatt, Glenn J., Ngan, Deborah K., Ning, Baitang, Pandit, Shraddha, Parthasarathi, Ramakrishnan, Patterson, Tucker A., Pavel, Alisa, Prabhu, Paulraj, Puzyn, Tomasz, Qu, Jiao, Roncaglioni, Alessandra, Roy, Kunal, Saarimäki, Laura Aliisa, Saavedra, Laura M., Sanches, Igor H., Schilter, Benoit, Selvaraj, Chandrabose, Serra, Angela, Shi, Wei, Singh, Prakrity, Singh, Sanjeev Kumar, Sogor, Catalina, Song, Meng, Sosnowska, Anita, Su, Limin, Sugiyama, Kei-ichi, Swirog, Marta, Tang, Yun, Teng, Yuefa, Tong, Weida, Tropsha, Alexander, Udrea, Ana-Maria, Velmurugan, Devadasan, Voigt, Melanie, Wang, Haobo, Wang, Xiaoqing, Wang, Zhongyu, Wang, Xueyu, Wei, Xiaoxuan, Wen, Zhining, Wu, Yiqu, Wyrzykowska, Ewelina, Xiao, Fang, Xie, Hong-Bin, Xu, Tuan, Xu, Liang, Yang, Xianhai, Yu, Haiying, Zhang, Yuxuan, Zhang, Jiachen, Zhao, Jingwen, Zhao, Yuanhui, Zhu, Minghua, Zhuang, Shulin, Zou, Wen

Source: In QSAR in Safety Evaluation and Risk Assessment 2023:xv-xviii

Fast computational chemistry methods applied to new anti-Ebola virus entry drugs - application for new therapeutic targets.

Authors: Udrea, Ana-Maria¹, Puia, Alin¹ alin2391@gmail.com, Mernea, Maria¹, Alexandrescu, Iulia¹, Avram, Speranta¹

Source: New Frontiers in Chemistry. 2017, Vol. 26 Issue 1, p1-10. 10p. 1 Diagram, 4 Charts, 1 Graph.

Subject Terms: *EBOLA virus disease, *SEROTONIN uptake inhibitors, *COMPUTATIONAL chemistry, *ANTIVIRAL agents, *QSAR models

PERSPECTIVES ON NATIONAL STRATEGY ON SOCIAL INCLUSION AND POVERTY REDUCTION (2014-2020) OF ROMANIA.

Authors: Udrea, Ana-Maria¹ anam.udrea@gmail.com

Source: Online Journal Modelling the New Europe. Mar2015, Issue 14, p90-106. 17p.

Subject Terms: *SOCIAL integration, *POVERTY reduction, *SOCIAL groups, *ECONOMICS, *GOVERNMENT policy, ROMANIAN politics & government, 1989-, POVERTY & society

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Influența ajustărilor propuse de auditorul independent asupra opiniei exprimate în raportul de audit.

Alternate Title: The Influence of the Independent Auditor's Proposed Adjustments on the Opinion Expressed in the Audit Report.

Authors: TODEA, Nicolae, JOLDOȘ (UDREA), Ana Maria, STANCIU, Ionela Cornelia

Source: Audit Financiar. Jul2011, Vol. 9 Issue 7, p21-26. 6p.

Subject Terms: *Auditors' reports, *Financial statements, *Investments, *Decision making, *Capital, *Business records, *Auditors, *Assets (Accounting)

Low Blue Dose Photodynamic Therapy with Porphyrin-Iron Oxide Nanoparticles Complexes: In Vitro Study on Human Melanoma Cells.

Authors: Nistorescu, Simona^1,2 (AUTHOR) badea_andreea08@yahoo.com, Udrea, Ana-Maria^1,3 (AUTHOR) ana.udrea@inflpr.ro, Badea, Madalina Andreea² (AUTHOR) roua.popescu@drd.unibuc.ro, Lungu, Iulia^1,4 (AUTHOR) ecaterina.andronescu@upb.ro, Boni, Mihai¹ (AUTHOR) mihai.boni@inflpr.ro, Tozar, Tatiana¹ (AUTHOR) tatiana.alexandru@inflpr.ro, Dumitrache, Florian¹ (AUTHOR) florian.dumitrache@inflpr.ro, Maraloiu, Valentin-Adrian⁵ (AUTHOR) maraloiu@infim.ro, Popescu, Roua Gabriela² (AUTHOR) ancadinischiotu@yahoo.com, Fleaca, Claudiu¹ (AUTHOR) claudiu.fleaca@inflpr.ro, Andronescu, Ecaterina⁴ (AUTHOR), Dinischiotu, Anca² (AUTHOR), Staicu, Angela¹ (AUTHOR) angela.staicu@inflpr.ro, Balas, Mihaela² (AUTHOR) angela.staicu@inflpr.ro

Source: Pharmaceutics. Dec2021, Vol. 13 Issue 12, p2130-2130. 1p.

Subject Terms: *IRON oxide nanoparticles, *PHOTODYNAMIC therapy, *BIOLOGICAL assay, *IRON oxides, *IRON porphyrins, *NANOPARTICLES, *REACTIVE oxygen species, *DACARBAZINE