Employing splice-switching oligonucleotides and AAVrh74.U7 snRNA to target insulin receptor splicing and cancer hallmarks in osteosarcoma

Authors: Safiya Khurshid, Akila S. Venkataramany, Matias Montes, John F. Kipp, Ryan D. Roberts, Nicolas Wein, Frank Rigo, Pin-Yi Wang, Timothy P. Cripe, Dawn S. Chandler

Source: Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200908- (2024)

Subject Terms: MT: Regular Issue, alternative splicing, insulin receptor, splice-switching oligonucleotides, U7 snRNA, osteosarcoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950329924001504; https://doaj.org/toc/2950-3299

Access URL: https://doaj.org/article/64d96cc962ff4b389d77c5c42a9d9331

Steady-State Dynamics of Cajal Body Components in the Xenopus Germinal Vesicle

Authors: Handwerger, Korie E., Murphy, Christine, Gall, Joseph G.

Source: The Journal of Cell Biology, 2003 Feb . 160(4), 495-504.

Access URL: https://www.jstor.org/stable/1621448

Antisense Oligonucleotides Promote Exon Inclusion and Correct the Common c.-32-13T>G GAA Splicing Variant in Pompe Disease

Authors: Erik van der Wal, Atze J. Bergsma, Joon M. Pijnenburg, Ans T. van der Ploeg, W.W.M. Pim Pijnappel

Source: Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 90-100 (2017)

Subject Terms: Pompe disease, U7 snRNA screen, antisense oligonucleotides, exon inclusion, pre-mRNA splicing, metabolic disorder, lysosomal storage disorder, IVS1, lysosomal storage disease, acid α-glucosidase, GAA, skeletal muscle, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253117301397; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/0e5e51118ddd4097bbff11825f019377

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