The Oncolytic Avian Reovirus p17 Protein Inhibits Invadopodia Formation in Murine Melanoma Cancer Cells by Suppressing the FAK/Src Pathway and the Formation of theTKs5/NCK1 Complex

Authors: Chao-Yu Hsu, Jyun-Yi Li, En-Ying Yang, Tsai-Ling Liao, Hsiao-Wei Wen, Pei-Chien Tsai, Tz-Chuen Ju, Lon-Fye Lye, Brent L. Nielsen, Hung-Jen Liu

Source: Viruses, Vol 16, Iss 7, p 1153 (2024)

Subject Terms: avian reoviruses, p17, p53/PTEN, FAK/Src, TKs5/NCK1 complex, Rab40b, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/7/1153; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/a9d709f2c4354e8fbb700714f8004fe2

A selective inhibitor of the NLRP3 inflammasome as a potential therapeutic approach for neuroprotection in a transgenic mouse model of Huntington’s disease

Authors: Kai-Po Chen, Kuo-Feng Hua, Fu-Ting Tsai, Ting-Yu Lin, Chih-Yuan Cheng, Ding-I. Yang, Hsien-Ta Hsu, Tz-Chuen Ju

Source: Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)

Subject Terms: Huntington’s disease (HD), Interleukin‐1β (IL‐1β), Mutated huntingtin (mHTT), Nucleotide oligomerization domain-like receptor protein 3 inflammasome (NLRP3 inflammasome), Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/f2d8f3d48b8b49b1a403ac4aecb9c14a

Eucalyptus essential oils inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through reducing MAPK and NF-κB pathways

Authors: Chen-Lung Ho, Lan-Hui Li, Yueh-Chun Weng, Kuo-Feng Hua, Tz-Chuen Ju

Source: BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)

Subject Terms: Anti-inflammation, Eucalyptus essential oils, Macrophages, Cytokine, Lipopolysaccharide, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12906-020-02999-0; https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/d20b92716b46435eac42d5a99d3003fa

Critical Role for the NLRP3 Inflammasome in Mediating IL-1β Production in Shigella sonnei-Infected Macrophages

Authors: Lan-Hui Li, Tzu-Ling Chen, Hsiao-Wen Chiu, Chung-Hua Hsu, Chien-Chun Wang, Tzu-Ting Tai, Tz-Chuen Ju, Fang-Hsin Chen, Oleg V. Chernikov, Wen-Chiuan Tsai, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: shigellosis, NLRP3 inflammasome, macrophages, P2X7 receptor, mitochondria, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01115/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/df481b25e45b40a797e039b664e6e64e

Mechanistic Insight Into the Activation of the NLRP3 Inflammasome by Neisseria gonorrhoeae in Macrophages

Authors: Lan-Hui Li, Jia-Sing Lin, Hsiao-Wen Chiu, Wen-Yu Lin, Tz-Chuen Ju, Fang-Hsin Chen, Oleg V. Chernikov, May-Lan Liu, Jen-Che Chang, Chung-Hua Hsu, Ann Chen, Shuk-Man Ka, Hong-Wei Gao, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: Neisseria gonorrhoeae, NLRP3 inflammasome, macrophages, signal transduction, bactericidal activity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.01815/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/99e5dcda26144f25b5a723ff3f967933

Nocturnal One-Hour Lighting Stimulates Gonadal Development and Lowers Fat Deposition in Male Mule Ducks

Authors: Tz-Chuen Ju, Kai-Chien Tsao, Tzu-Yu Liu, Shyi-Kuen Yang

Source: Animals, Vol 11, Iss 3, p 614 (2021)

Subject Terms: fat deposition, gonadal development, mule duck, photoperiod, Veterinary medicine, SF600-1100, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2615/11/3/614; https://doaj.org/toc/2076-2615

Access URL: https://doaj.org/article/93d3bf2ce2774cadaa6602d1f271b151

Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome

Authors: Chih-Yu Hsieh, Lan-Hui Li, Yulin Lam, Zhanxiong Fang, Chin Heng Gan, Yerra Koteswara Rao, Hsiao-Wen Chiu, Wei-Ting Wong, Tz-Chuen Ju, Fang-Hsin Chen, Oleg V. Chernikov, May-Lan Liu, Chung-Hua Hsu, Kuo-Feng Hua

Source: Cells, Vol 9, Iss 2, p 279 (2020)

Subject Terms: 4-hydroxy auxarconjugatin b, nlrp3 inflammasome, mitochondria, autophagy, gouty inflammation, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/2/279; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/724b7b5f8c884c71b2c2212ec09c509f

A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP.

Authors: Lan-Hui Li, Tz-Chuen Ju, Chih-Yu Hsieh, Wei-Chih Dong, Wan-Tze Chen, Kuo-Feng Hua, Wei-Jung Chen

Source: PLoS ONE, Vol 12, Iss 7, p e0182057 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5531531?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/49c6caee184945d59606c208ae57c072

Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.

Authors: Yu-Ju Liu, Tz-Chuen Ju, Hui-Mei Chen, Yu-Sung Jang, Li-Ming Lee, Hsing-Lin Lai, Hua-Chia Tai, Jim-Min Fang, Yun-Lian Lin, Pang-Hsien Tu, Yijuang Chern

Source: Human Molecular Genetics; Feb2015, Vol. 24 Issue 3, p787-801, 15p, 2 Diagrams, 1 Chart, 6 Graphs

Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington's disease.

Authors: Tz-Chuen Ju^1,2, Hui-Mei Chen², Jiun-Tsai Lin², Ching-Pang Chang², Wei-Cheng Chang¹, Jheng-Jie Kang¹, Cheng-Pu Sun³, Mi-Hua Tao², Pang-Hsien Tu², Chen Chang², Dickson, Dennis W.⁴, Yijuang Chern^1,2 bmychern@ibms.sinica.edu.tw

Source: Journal of Cell Biology. 7/25/2011, Vol. 194 Issue 2, p209-227. 19p.

Subject Terms: *PROTEIN kinases, *HOMEOSTASIS, *HUNTINGTON disease, *LABORATORY mice, *TRANSGENIC mice, *NEURONS, *CELL death