Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP

Authors: Olson, Samuel W., Turner, Anne-Marie W., Arney, J. Winston, Saleem, Irfana, Weidmann, Chase A., Margolis, David M., Weeks, Kevin M., Mustoe, Anthony M.

Source: In Molecular Cell 5 May 2022 82(9):1708-1723

The histone methyltransferase SETD2 regulates HIV expression and latency.

Authors: Bussey-Sutton, Cameron R.¹, Ward, Airlie^2,3, Fox, Joshua A.^2,3, Turner, Anne-Marie W.^2,3, Peterson, Jackson J.^3,4, Emery, Ann⁵, Longoria, Arturo R.^2,3, Gomez-Martinez, Ismael⁶, Jones, Corbin⁶, Hepperla, Austin⁶, Margolis, David M.^2,3,4, Strahl, Brian D.¹, brian_strahl@med.unc.edu, Browne, Edward P.^2,3,4, brian_strahl@med.unc.edu

Source: PLoS Pathogens; 6/7/2024, Vol. 20 Issue 6, p1-35, 35p

Curing HIV: Seeking to Target and Clear Persistent Infection

Authors: Margolis, David M., Archin, Nancie M., Cohen, Myron S., Eron, Joseph J., Ferrari, Guido, Garcia, J. Victor, Gay, Cynthia L., Goonetilleke, Nilu, Joseph, Sarah B., Swanstrom, Ronald, Turner, Anne-Marie W., Wahl, Angela

Source: In Cell 2 April 2020 181(1):189-206

Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency

Authors: Alfonso-Dunn, Roberto, Turner, Anne-Marie W., Jean Beltran, Pierre M., Arbuckle, Jesse H., Budayeva, Hanna G., Cristea, Ileana M., Kristie, Thomas M.

Source: In Cell Host & Microbe 12 April 2017 21(4):507-517

An HIV-Encoded Antisense Long Noncoding RNA Epigenetically Regulates Viral Transcription

Authors: Saayman, Sheena, Ackley, Amanda, Turner, Anne-Marie W, Famiglietti, Marylinda, Bosque, Alberto, Clemson, Matthew, Planelles, Vicente, Morris, Kevin V

Source: In Molecular Therapy June 2014 22(6):1164-1175

Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader

Authors: Potjewyd, Frances, Turner, Anne-Marie W., Beri, Joshua, Rectenwald, Justin M., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Margolis, David M., Pearce, Kenneth H., Herring, Laura E., James, Lindsey I.

Source: Cell chemical biology. 27(1):47-56.e15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135264509.0x000001&indx=1&recIds=ETOCvdc_100135264509.0x000001

Chemically Modified Oligonucleotides Modulate an Epigenetically Varied and Transient Form of Transcription Silencing of HIV-1 in Human Cells

Authors: Knowling, Stuart, Stapleton, Kenneth, Turner, Anne-Marie W, Uhlmann, Eugen, Lehmann, Thomas, Vollmer, Jörg, Morris, Kevin V

Source: In Molecular Therapy - Nucleic Acids 2012 1

Mobilization-competent Lentiviral Vector–mediated Sustained Transcriptional Modulation of HIV-1 Expression

Authors: Turner, Anne-Marie W, De La Cruz, Justin, Morris, Kevin V

Source: In Molecular Therapy February 2009 17(2):360-368

Mutational Analysis of the Escherichia coli DEAD Box Protein CsdAv.

Authors: Turner, Anne-Marie W., Love, Cheraton F., Alexander, Rebecca W.

Source: Journal of Bacteriology; April 2007, Vol. 189 Issue 7, p2769-2776, 8p

Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal.

Authors: Turner, Anne-Marie W., Dronamraju, Raghuvar, Potjewyd, Frances, James, Katherine S., Winecoff, Daniel K., Kirchherr, Jennifer L., Archin, Nancie M., Browne, Edward P., Strahl, Brian D., Margolis, David M., James

Source: ACS Infectious Diseases; 7/10/2020, Vol. 6 Issue 7, p1719-1733, 15p

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Analysis of HSV Viral Reactivation in Explants of Sensory Neurons

Authors: Arbuckle, Jesse H., Turner, Anne‐Marie W., Kristie, Thomas M.

Source: Current Protocols in Microbiology; November 2014, Vol. 35 Issue: 1 p14E.6.1-14E.6.21, 13161p

Quantitative Analysis of HSV Gene Expression during Lytic Infection

Authors: Turner, Anne‐Marie W., Arbuckle, Jesse H., Kristie, Thomas M.

Source: Current Protocols in Microbiology; November 2014, Vol. 35 Issue: 1 p14E.5.1-14E.5.27, 13077p

Transcriptional gene silencing as a genetic therapy for HIV-1

Authors: Turner, Anne-Marie W, Morris, Kevin V

Source: Future HIV Therapy; July 2008, Vol. 2 Issue: 4 p339-349, 11p

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Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.

Authors: Falcinelli, Shane D., Peterson, Jackson J., Turner, Anne-Marie W., Irlbeck, David, Read, Jenna, Raines, Samuel L. M., James, Katherine S., Sutton, Cameron, Sanchez, Anthony, Emery, Ann, Sampey, Gavin, Ferris, Robert, Allard, Brigitte, Ghofrani, Simon, Kirchherr, Jennifer L., Baker, Caroline, Kuruc, JoAnn D., Gay, Cynthia L., James, Lindsey I., Guoxin Wu

Source: Journal of Clinical Investigation. 4/15/2022, Vol. 132 Issue 8, p1-14. 14p.

Subjects: HIV infections, PROTEINS, VIRAL physiology, NUCLEAR proteins, MICROBIOLOGY, PHENOMENOLOGICAL biology, NF-kappa B, RNA, RESEARCH funding, T cells, TRANSCRIPTION factors, HIV, ANIMALS