Modulation of Cancer-Associated Fibrotic Stroma by An Integrin αvβ3 Targeting Protein for Pancreatic Cancer Treatment

Authors: Turaga, Ravi Chakra, Sharma, Malvika, Mishra, Falguni, Krasinskas, Alyssa, Yuan, Yi, Yang, Jenny J., Wang, Shiyuan, Liu, Chunfeng, Li, Sun, Liu, Zhi-Ren

Source: In Cellular and Molecular Gastroenterology and Hepatology 2021 11(1):161-179

Proteome Landscape of Epithelial-to-Mesenchymal Transition (EMT) of Retinal Pigment Epithelium Shares Commonalities With Malignancy-Associated EMT

Authors: Sripathi, Srinivasa R., Hu, Ming-Wen, Turaga, Ravi Chakra, Mertz, Joseph, Liu, Melissa M., Wan, Jun, Maruotti, Julien, Wahlin, Karl J., Berlinicke, Cynthia A., Qian, Jiang, Zack, Donald J.

Source: In Molecular & Cellular Proteomics 2021 20

Precision detection of liver metastasis by collagen-targeted protein MRI contrast agent

Authors: Salarian, Mani, Yang, Hua, Turaga, Ravi Chakra, Tan, Shanshan, Qiao, Jingjuan, Xue, Shenghui, Gui, Zongxiang, Peng, Guangda, Han, Hongwei, Mittal, Pardeep, Grossniklaus, Hans E., Yang, Jenny J.

Source: In Biomaterials December 2019 224

Overexpression of Smac by an Armed Vesicular Stomatitis Virus Overcomes Tumor Resistance

Authors: Li, Weike, Turaga, Ravi Chakra, Li, Xin, Sharma, Malvika, Enadi, Zahra, Dunham Tompkins, Sydney Nicole, Hardy, Kyle Christian, Mishra, Falguni, Tsao, Jun, Liu, Zhi-ren, Fan, Daping, Luo, Ming

Source: In Molecular Therapy - Oncolytics 27 September 2019 14:188-195

Early detection and staging of chronic liver diseases with a protein MRI contrast agent

Authors: Salarian, Mani, Turaga, Ravi, Xue, Shenghui, Nezafati, Maysam, Hekmatyar, Khan, Qiao, Jingjuan, Zhang, Yinwei, Tan, Shanshan, Ibhagui, Oluwatosin, Hai, Yan, Li, Jibiao, Mukkavilli, Rao, Sharma, Malvika, Mittal, Pardeep, Min, Xiaoyi, Keilholz, Shella, Yu, Liqing, Qin, Gengshen, Farris, Alton, Liu, Zhi-Ren, Yang, Jenny

Source: Nature communications. 10(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190871985.0x000001&indx=1&recIds=ETOCvdc_100190871985.0x000001

IKKβ Inhibition Attenuates Epithelial Mesenchymal Transition of Human Stem Cell-Derived Retinal Pigment Epithelium.

Authors: Sripathi, Srinivasa R., Hu, Ming-Wen, Turaga, Ravi Chakra, Mikeasky, Rebekah, Satyanarayana, Ganesh, Cheng, Jie, Duan, Yukan, Maruotti, Julien, Wahlin, Karl J., Berlinicke, Cynthia A., Qian, Jiang, Esumi, Noriko, Zack, Donald J.

Source: Cells (2073-4409); Apr2023, Vol. 12 Issue 8, p1155, 18p

Subject Terms: EPITHELIAL-mesenchymal transition, RHODOPSIN, TRANSFORMING growth factors-beta, MACULAR degeneration, TUMOR necrosis factors, PROLIFERATIVE vitreoretinopathy

PLK1 and AURKB phosphorylate survivin differentially to affect proliferation in racially distinct triple-negative breast cancer.

Authors: Garlapati, Chakravarthy, Joshi, Shriya, Bhattarai, Shristi, Krishnamurthy, Jayashree, Turaga, Ravi Chakra, Nguyen, Thi, Li, Xiaoxian, Aneja, Ritu

Source: Cell Death & Disease; Jan2023, Vol. 14 Issue 1, p1-13, 13p

Simultaneously targeting cancer-associated fibroblasts and angiogenic vessel as a treatment for TNBC

Authors: Sharma, Malvika, Turaga, Ravi Chakra, Yuan, Yi, Satyanarayana, Ganesh, Mishra, Falguni, Bian, Zhen, Liu, Wei, Sun, Li, Yang, Jenny, Liu, Zhi-Ren

Source: Journal of experimental medicine. 218(4):e20200712-e20200712

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626302000&indx=1&recIds=ETOCRN626302000

Proagio: a protein designed to target integrin alpha V beta 3 outside ligand binding site is an effective way to target activated hepatic stellate cells

Authors: Turaga, Ravi Chakra, Satyanarayana, Ganesh, Sharma, Malvika, Yang, Jenny, Gracia-Sancho, Jordi, Liu, Zhi-Ren

Source: Journal of hepatology. 73(S1):S214-S214

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120845959.0x000001&indx=1&recIds=ETOCvdc_100120845959.0x000001

Pyruvate kinase M2 regulates fibrosis development and progression by controlling glycine auxotrophy in myofibroblasts.

Authors: Satyanarayana, Ganesh, Turaga, Ravi Chakra, Sharma, Malvika, Siming Wang, Mishra, Falguni, Guangda Peng, Xiaonan Deng, Jenny Yang, Zhi-Ren Liu

Source: Theranostics; 2021, Vol. 11 Issue 19, p9331-9341, 11p

Monoethanolamine-induced glucose deprivation promotes apoptosis through metabolic rewiring in prostate cancer.

Authors: Garlapati, Chakravarthy, Joshi, Shriya, Turaga, Ravi Chakra, Mishra, Manjari, Reid, Michelle D., Kapoor, Shobhna, Artinian, Liana, Rehder, Vincent, Aneja, Ritu

Source: Theranostics; 2021, Vol. 11 Issue 18, p9089-9106, 18p

Targeting integrin αvβ3 by a rationally designed protein for chronic liver disease treatment.

Authors: Turaga, Ravi Chakra¹, Satyanarayana, Ganesh¹, Sharma, Malvika¹, Yang, Jenny J.², Wang, Shiyuan³, Liu, Chunfeng³, Li, Sun², Yang, Hua⁴, Grossniklaus, Hans⁴, Farris, Alton Brad⁵, Gracia-Sancho, Jordi⁶, Liu, Zhi-Ren¹ zliu8@gsu.edu

Source: Communications Biology. 9/16/2021, Vol. 4 Issue 1, p1-10. 10p.

Subject Terms: *INTEGRINS, *CHRONIC diseases, *FIBROSIS, *BLOOD flow, *KUPFFER cells

THU150 - Proagio: a protein designed to target integrin alpha V beta 3 outside ligand binding site is an effective way to target activated hepatic stellate cells

Authors: Turaga, Ravi Chakra, Satyanarayana, Ganesh, Sharma, Malvika, Yang, Jenny, Gracia-Sancho, Jordi, Liu, Zhi-Ren

Source: In Journal of Hepatology August 2020 73 Supplement 1:S214-S214

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A novel microtubule-modulating agent EM011 inhibits angiogenesis by repressing the HIF-1α axis and disrupting cell polarity and migration.

Authors: Karna, Prasanthi, Rida, Padmashree C.G., Turaga, Ravi Chakra, Gao, Jinmin, Gupta, Meenakshi, Fritz, Andreas, Werner, Erica, Yates, Clayton, Zhou, Jun, Aneja, Ritu

Source: Carcinogenesis; Sep2012, Vol. 33 Issue 9, p1769-1781, 13p

Subject Terms: MICROTUBULES, NEOVASCULARIZATION inhibitors, HYPOXIA-inducible factor 1, CELL migration, MORPHOGENESIS, ENDOTHELIAL cells, ACTIN

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