Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms

Authors: Chovanec, Jack, Tunc, Ilker, Hughes, Jason, Halstead, Joseph, Mateja, Allyson, Liu, Yihui, O’Connell, Michael P., Kim, Jiwon, Park, Young Hwan, Wang, Qinlu, Le, Quang, Pirooznia, Mehdi, Trivedi, Neil N., Bai, Yun, Yin, Yuzhi, Hsu, Amy P., McElwee, Joshua, Lassiter, Sheryce, Nelson, Celeste, Bandoh, Judy, DiMaggio, Thomas, Šelb, Julij, Rijavec, Matija, Carter, Melody C., Komarow, Hirsh D., Sabato, Vito, Steinberg, Joshua, Hafer, Kurt M., Feuille, Elizabeth, Hourigan, Christopher S., Lack, Justin, Khoury, Paneez, Maric, Irina, Zanotti, Roberta, Bonadonna, Patrizia, Schwartz, Lawrence B., Milner, Joshua D., Glover, Sarah C., Ebo, Didier G., Korošec, Peter, Caughey, George H., Brittain, Erica H., Busby, Ben, Metcalfe, Dean D., Lyons, Jonathan J.

Source: In Blood Advances 9 May 2023 7(9):1796-1810

Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques

Authors: AlJanahi, Aisha A., Lazzarotto, Cicera R., Chen, Shirley, Shin, Tae-Hoon, Cordes, Stefan, Fan, Xing, Jabara, Isabel, Zhou, Yifan, Young, David J., Lee, Byung-Chul, Yu, Kyung-Rok, Li, Yuesheng, Toms, Bradley, Tunc, Ilker, Hong, So Gun, Truitt, Lauren L., Klermund, Julia, Andrieux, Geoffroy, Kim, Miriam Y., Cathomen, Toni, Gill, Saar, Tsai, Shengdar Q., Dunbar, Cynthia E.

Source: Molecular therapy. 30(1):209-222

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170950036.0x000001&indx=1&recIds=ETOCvdc_100170950036.0x000001

Higher levels of allograft injury in black patients early after heart transplantation

Authors: Doshi, Amar, Shah, Keyur B., Agbor-Enoh, Sean, Tushak, Zackary, Garcia, Victoria, Kong, Hyesik, Jang, Moon K., Hsu, Steven, Feller, Erika D., Rodrigo, Maria E., Najjar, Samer S., Tunc, Ilker, Yang, Yanqin, Lee, Seiyon, Solomon, Michael A., Berry, Gerald, Marboe, Charles, Shah, Palak, Valantine, Hannah A.

Source: Journal of heart and lung transplantation. 41(7):855-858

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100166592658.0x000001&indx=1&recIds=ETOCvdc_100166592658.0x000001

Performance of a blood-based screening test for the early detection of colorectal cancer.

Authors: Nakamura, Yoshiaki, Reiter, Johannes, Babiarz, Joshua, Srinivasan, Preethi, Haghshenas, Ehsan, Chen, Tzu-Chun, Liang, Nathan, Joshi, Jayashree, Huang, Hsiao-Yun, Kordi, Misagh, Gutman, Boris, Chan, Wen-Ching, Tunc, Ilker, Natarajan, Prashanthi, Jurdi, Adham A, Rabinowitz, Matthew, Mitchell, Bree, Kawli, Trupti, Aleshin, Alexey, Yoshino, Takayuki

Source: Journal of Clinical Oncology; 2025 Supplement 4, Vol. 43, p232-232, 307p

Donor-derived cell-free DNA accurately detects acute rejection in lung transplant patients, a multicenter cohort study

Authors: Jang, Moon Kyoo, Tunc, Ilker, Berry, Gerald J., Marboe, Charles, Kong, Hyesik, Keller, Michael B., Shah, Pali D., Timofte, Irina, Brown, Anne W., Ponor, Ileana L., Mutebi, Cedric, Philogene, Mary C., Yu, Kai, Iacono, Aldo, Orens, Jonathan B., Nathan, Steven D., Agbor-Enoh, Sean

Source: In Journal of Heart and Lung Transplantation August 2021 40(8):822-830

Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease

Authors: Tumburu, Laxminath, Ghosh-Choudhary, Shohini, Seifuddin, Fayaz T., Barbu, Emilia A., Yang, Simon, Ahmad, Maliha M., Wilkins, Lauren H.W., Tunc, Ilker, Sivakumar, Ishwarya, Nichols, James S., Dagur, Pradeep K., Yang, Shutong, Almeida, Luis E.F., Quezado, Zenaide M.N., Combs, Christian A., Lindberg, Eric, Bleck, Christopher K.E., Zhu, Jun, Shet, Arun S., Chung, Jay H., Pirooznia, Mehdi, Thein, Swee Lay ^*

Source: In Blood 3 June 2021 137(22):3116-3126

Use of donor-derived-cell-free DNA as a marker of early allograft injury in primary graft dysfunction (PGD) to predict the risk of chronic lung allograft dysfunction (CLAD)

Authors: Keller, Michael, Bush, Errol, Diamond, Joshua M., Shah, Pali, Matthew, Joby, Brown, Anne W, Sun, Junfeng, Timofte, Irina, Kong, Hyesik, Tunc, Ilker, Luikart, Helen, Iacono, Aldo, Nathan, Steven D., Khush, Kiran K., Orens, Jonathan, Jang, Moon, Agbor-Enoh, Sean

Source: In Journal of Heart and Lung Transplantation June 2021 40(6):488-493

Cell-Free DNA to Detect Heart Allograft Acute Rejection

Authors: Agbor-Enoh, Sean, Shah, Palak, Tunc, Ilker, Hsu, Steven, Russell, Stuart, Feller, Erika, Shah, Keyur, Rodrigo, Maria E., Najjar, Samer S., Kong, Hyesik, Pirooznia, Mehdi, Fideli, Ulgen, Bikineyeva, Alfiya, Marishta, Argit, Bhatti, Kenneth, Yang, Yanqin, Mutebi, Cedric, Yu, Kai, Kyoo Jang, Moon, Marboe, Charles, Berry, Gerald J., Valantine, Hannah A.

Source: Circulation. 143(12):1184-1197

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188867570.0x000001&indx=1&recIds=ETOCvdc_100188867570.0x000001

Identification of Genes Contributing to a Long Circadian Period in Drosophila Melanogaster

Authors: Kumar, Shailesh, Tunc, Ilker, Tansey, Terry R., Pirooznia, Mehdi, Harbison, Susan T.

Source: Journal of biological rhythms. 36(3):239-253

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626609039&indx=1&recIds=ETOCRN626609039

Circulating Lymphangioleiomyomatosis Tumor Cells With Loss of Heterozygosity in the TSC2 Gene Show Increased Aldehyde Dehydrogenase Activity

Authors: Pacheco-Rodríguez, Gustavo, Steagall, Wendy K., Samsel, Leigh, Dagur, Pradeep K., McCoy, J. Philip, Tunc, Ilker, Pirooznia, Mehdi, Wang, Ji-An, Darling, Thomas N., Moss, Joel

Source: In Chest August 2019 156(2):298-307

Effects of community structure on epidemic spread in an adaptive network

Authors: Tunc, Ilker, Shaw, Leah B.

Subject Terms: Quantitative Biology - Populations and Evolution, Computer Science - Social and Information Networks, Nonlinear Sciences - Adaptation and Self-Organizing Systems, Physics - Physics and Society

Access URL: http://arxiv.org/abs/1212.3229

Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis

Authors: Teague, Heather L., Varghese, Nevin J., Tsoi, Lam C., Dey, Amit K., Garshick, Michael S., Silverman, Joanna I., Baumer, Yvonne, Harrington, Charlotte L., Stempinski, Erin, Elnabawi, Youssef A., Dagur, Pradeep K., Cui, Kairong, Tunc, Ilker, Seifuddin, Fayaz, Joshi, Aditya A., Stansky, Elena, Purmalek, Monica M., Rodante, Justin A., Keel, Andrew, Aridi, Tarek Z., Carmona-Rivera, Carmelo, Sanda, Gregory E., Chen, Marcus Y., Pirooznia, Mehdi, McCoy, J. Philip, Jr., Gelfand, Joel M., Zhao, Keji, Gudjonsson, Johann E., Playford, Martin P., Kaplan, Mariana J., Berger, Jeffrey S., Mehta, Nehal N.

Source: In JACC: Basic to Translational Science February 2019 4(1):1-14

Donor-derived cell-free DNA predicts allograft failure and mortality after lung transplantation

Authors: Agbor-Enoh, Sean, Wang, Yan, Tunc, Ilker, Jang, Moon Kyoo, Davis, Andrew, De Vlaminck, Iwijn, Luikart, Helen, Shah, Pali D., Timofte, Irina, Brown, Anne W., Marishta, Argit, Bhatti, Kenneth, Gorham, Sasha, Fideli, Ulgen, Wylie, Jennifer, Grimm, David, Goodwin, Natalie, Yang, Yanqin, Patel, Kapil, Zhu, Jun, Iacono, Aldo, Orens, Jonathan B., Nathan, Steven D., Marboe, Charles, Berry, Gerald J., Quake, Stephen R., Khush, Kiran, Valantine, Hannah A.

Source: In EBioMedicine February 2019 40:541-553

Circulating cell-free DNA as a biomarker of tissue injury: Assessment in a cardiac xenotransplantation model

Authors: Agbor-Enoh, Sean, Chan, Joshua L., Singh, Avneesh, Tunc, Ilker, Gorham, Sasha, Zhu, Jun, Pirooznia, Mehdi, Corcoran, Philip C., Thomas, Marvin L., Lewis, Billeta G.T., Jang, Moon Kyoo, Ayares, David L., Horvath, Keith A., Mohiuddin, Muhammad M., Valantine, Hannah

Source: In Journal of Heart and Lung Transplantation August 2018 37(8):967-975

Late manifestation of alloantibody-associated injury and clinical pulmonary antibody-mediated rejection: Evidence from cell-free DNA analysis

Authors: Agbor-Enoh, Sean, Jackson, Annette M., Tunc, Ilker, Berry, Gerald J., Cochrane, Adam, Grimm, David, Davis, Andrew, Shah, Pali, Brown, Anne W., Wang, Yan, Timofte, Irina, Shah, Palak, Gorham, Sasha, Wylie, Jennifer, Goodwin, Natalie, Jang, Moon Kyoo, Marishta, Argit, Bhatti, Kenneth, Fideli, Ulgen, Yang, Yanqin, Luikart, Helen, Cao, Zeling, Pirooznia, Mehdi, Zhu, Jun, Marboe, Charles, Iacono, Aldo, Nathan, Steven D., Orens, Jonathan, Valantine, Hannah A., Khush, Kiran

Source: In Journal of Heart and Lung Transplantation July 2018 37(7):925-932

Applying rigor and reproducibility standards to assay donor-derived cell-free DNA as a non-invasive method for detection of acute rejection and graft injury after heart transplantation

Authors: Agbor-Enoh, Sean, Tunc, Ilker, De Vlaminck, Iwijn, Fideli, Ulgen, Davis, Andrew, Cuttin, Karen, Bhatti, Kenneth, Marishta, Argit, Solomon, Michael A., Jackson, Annette, Graninger, Grace, Harper, Bonnie, Luikart, Helen, Wylie, Jennifer, Wang, Xujing, Berry, Gerald, Marboe, Charles, Khush, Kiran, Zhu, Jun, Valantine, Hannah

Source: In Journal of Heart and Lung Transplantation September 2017 36(9):1004-1012

Rhesus iPSC Safe Harbor Gene-Editing Platform for Stable Expression of Transgenes in Differentiated Cells of All Germ Layers

Authors: Hong, So Gun, Yada, Ravi Chandra, Choi, Kyujoo, Carpentier, Arnaud, Liang, T. Jake, Merling, Randall K., Sweeney, Colin L., Malech, Harry L., Jung, Moonjung, Corat, Marcus A.F., AlJanahi, Aisha A., Lin, Yongshun, Liu, Huimin, Tunc, Ilker, Wang, Xujing, Palisoc, Maryknoll, Pittaluga, Stefania, Boehm, Manfred, Winkler, Thomas, Zou, Jizhong, Dunbar, Cynthia E.

Source: In Molecular Therapy 4 January 2017 25(1):44-53

Properties of global‐ and local‐ancestry adjustments in genetic association tests in admixed populations

Authors: Martin, Eden R., Tunc, Ilker, Liu, Zhi, Slifer, Susan H., Beecham, Ashley H., Beecham, Gary W.

Source: Genetic epidemiology. 42(2):214-229

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087394076.0x000001&indx=1&recIds=ETOCvdc_100087394076.0x000001

Comprehensive analysis of differentially methylated regions in colorectal cancer (CRC).

Authors: Solari, Omid, Constantin, Tudor, Jiang, Yuqian, Chan, Wengching, Tunc, Ilker, Srinivasan, Preethi, Kordi, Misagh, Santaguida, Marianne, Mitchell, Breeana L., Aleshin, Alexey, Swenerton, Ryan, Babiarz, Joshua, Kawli, Trupti, Reiter, Johannes G.

Source: Journal of Clinical Oncology; 2024 Supplement 3, Vol. 42, p73-73, 235p

LncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA

Authors: Seifuddin, Fayaz, Singh, Komudi, Suresh, Abhilash, Judy, Jennifer T., Chen, Yun-Ching, Chaitankar, Vijender, Tunc, Ilker, Ruan, Xiangbo, Li, Ping, Chen, Yi, Cao, Haiming, Lee, Richard S., Goes, Fernando S., Zandi, Peter P., Jafri, M. Saleet, Pirooznia, Mehdi

Source: Scientific data. 7(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176323778.0x000001&indx=1&recIds=ETOCvdc_100176323778.0x000001