Crenigacestat blocking notch pathway reduces liver fibrosis in the surrounding ecosystem of intrahepatic CCA viaTGF-β inhibition

Authors: Serena Mancarella, Isabella Gigante, Grazia Serino, Elena Pizzuto, Francesco Dituri, Maria F. Valentini, Jingxiao Wang, Xin Chen, Raffaele Armentano, Diego F. Calvisi, Gianluigi Giannelli

Source: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-14 (2022)

Subject Terms: Tissue microenvironment, Liver fibrosis, Tumor stroma crosstalk, Crenigacestat, Smad2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/04d9818126634bcbb9a920a39c75e01a