Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

Authors: Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin, Uzi Gileadi, Salvatore Valvo, Margarida Rei, Corinna Kulicke, Ji-Li Chen, Vitul Jain, Victoria K. Woodcock, Huw Colin-York, Andreas V. Hadjinicolaou, Youxin Kong, Viveka Mayya, Julie M. Mazet, Gracie-Jennah Mead, Joshua A. Bull, Pramila Rijal, Christopher W. Pugh, Alain R. Townsend, Audrey Gérard, Lars R. Olsen, Marco Fritzsche, Tudor A. Fulga, Michael L. Dustin, E. Yvonne Jones, Vincenzo Cerundolo

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0037fd20318049ccb1e0d08f25e77331

Publisher Correction: Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

Authors: Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin, Uzi Gileadi, Salvatore Valvo, Margarida Rei, Corinna Kulicke, Ji-Li Chen, Vitul Jain, Victoria K. Woodcock, Huw Colin-York, Andreas V. Hadjinicolaou, Youxin Kong, Viveka Mayya, Julie M. Mazet, Gracie-Jennah Mead, Joshua A. Bull, Pramila Rijal, Christopher W. Pugh, Alain R. Townsend, Audrey Gérard, Lars R. Olsen, Marco Fritzsche, Tudor A. Fulga, Michael L. Dustin, E. Yvonne Jones, Vincenzo Cerundolo

Source: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c91684507e624290b137868f21bb7e7e

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells

Authors: Elizabeth M. McNeill, Chloe Warinner, Stephen Alkins, Alicia Taylor, Hansine Heggeness, Todd F. DeLuca, Tudor A. Fulga, Dennis P. Wall, Leslie C. Griffith, David Van Vactor

Source: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b55a3441b07e4959ac857894059e3df7

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

Authors: Eva Gonçalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis, Laura Fachal, Sumeet Pandey, Jochen Kammermeier, Nicholas M. Croft, Carsten Posovszky, Astor Rodrigues, Richard K. Russell, Farah Barakat, Marcus K. H. Auth, Robert Heuschkel, Matthias Zilbauer, Krzysztof Fyderek, Christian Braegger, Simon P. Travis, Jack Satsangi, Miles Parkes, Nikhil Thapar, Helen Ferry, Julie C. Matte, Kimberly C. Gilmour, Andrzej Wedrychowicz, Peter Sullivan, Carmel Moore, Jennifer Sambrook, Willem Ouwehand, David Roberts, John Danesh, Toni A. Baeumler, Tudor A. Fulga, Mohammad Karaminejadranjbar, Ahmed Ahmed, Rachel Wilson, Jeffrey C. Barrett, Abdul Elkadri, Anne M. Griffiths, COLORS in IBD group investigators, Oxford IBD cohort study investigators, INTERVAL Study, Swiss IBD cohort investigators, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, Scott B. Snapper, Neil Shah, Aleixo M. Muise, David C. Wilson, Holm H. Uhlig, Carl A. Anderson

Source: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2613668b99c441b1b30bfa2765e3a533

MicroRNAs Regulate Multiple Aspects of Locomotor Behavior in Drosophila

Authors: Nathan C. Donelson, Richa Dixit, Israel Pichardo-Casas, Eva Y. Chiu, Robert T. Ohman, Justin B. Slawson, Mason Klein, Tudor A. Fulga, David Van Vactor, Leslie C. Griffith

Source: G3: Genes, Genomes, Genetics, Vol 10, Iss 1, Pp 43-55 (2020)

Subject Terms: microrna, motor behavior, drosophila melanogaster, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2160-1836

Access URL: https://doaj.org/article/45493e30110344ea93342c481fc3d672

Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression

Authors: David J. H. F. Knapp, Yale S. Michaels, Max Jamilly, Quentin R. V. Ferry, Hector Barbosa, Thomas A. Milne, Tudor A. Fulga

Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/088592c408394975893eeb5eb3ce5546

Precise tuning of gene expression levels in mammalian cells

Authors: Yale S. Michaels, Mike B. Barnkob, Hector Barbosa, Toni A. Baeumler, Mary K. Thompson, Violaine Andre, Huw Colin-York, Marco Fritzsche, Uzi Gileadi, Hilary M. Sheppard, David J. H. F. Knapp, Thomas A. Milne, Vincenzo Cerundolo, Tudor A. Fulga

Source: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f84f595575f647518a682f40b466a3e0

Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

Authors: Eva Gonçalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis, Laura Fachal, Sumeet Pandey, Jochen Kammermeier, Nicholas M. Croft, Carsten Posovszky, Astor Rodrigues, Richard K. Russell, Farah Barakat, Marcus K. H. Auth, Robert Heuschkel, Matthias Zilbauer, Krzysztof Fyderek, Christian Braegger, Simon P. Travis, Jack Satsangi, Miles Parkes, Nikhil Thapar, Helen Ferry, Julie C. Matte, Kimberly C. Gilmour, Andrzej Wedrychowicz, Peter Sullivan, Carmel Moore, Jennifer Sambrook, Willem Ouwehand, David Roberts, John Danesh, Toni A. Baeumler, Tudor A. Fulga, Eli M Carrami, Ahmed Ahmed, Rachel Wilson, Jeffrey C. Barrett, Abdul Elkadri, Anne M. Griffiths, COLORS in IBD group investigators, Oxford IBD cohort study investigators, INTERVAL Study, Swiss IBD cohort investigators, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, Scott B. Snapper, Neil Shah, Aleixo M. Muise, David C. Wilson, Holm H. Uhlig, Carl A. Anderson

Source: Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/5c86d325bfef42dd9f9c9aa2ea68a8c9

MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila

Authors: Patricia R. Goodwin, Alice Meng, Jessie Moore, Michael Hobin, Tudor A. Fulga, David Van Vactor, Leslie C. Griffith

Source: Cell Reports, Vol 23, Iss 13, Pp 3776-3786 (2018)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124718308593; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/d1eeba5feae442a084db8d9f86b34512

Addendum: Precise tuning of gene expression levels in mammalian cells

Authors: Yale S. Michaels, Mike B. Barnkob, Hector Barbosa, Toni A. Baeumler, Mary K. Thompson, Violaine Andre, Huw Colin-York, Marco Fritzsche, Uzi Gileadi, Hilary M. Sheppard, David J. H. F. Knapp, Thomas A. Milne, Vincenzo Cerundolo, Tudor A. Fulga

Source: Nature Communications, Vol 10, Iss 1, Pp 1-3 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f982718f87894f9b9dd74cb5a98758c7

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering

Authors: Qianxin Wu, Quentin R. V. Ferry, Toni A. Baeumler, Yale S. Michaels, Dimitrios M. Vitsios, Omer Habib, Roland Arnold, Xiaowei Jiang, Stefano Maio, Bruno R. Steinkraus, Marta Tapia, Paolo Piazza, Ni Xu, Georg A. Holländer, Thomas A. Milne, Jin-Soo Kim, Anton J. Enright, Andrew R. Bassett, Tudor A. Fulga

Source: Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/db4eb21f42e2466d9fc7c9b4e4aa2f37

A multiplexable TALE-based binary expression system for in vivo cellular interaction studies

Authors: Markus Toegel, Ghows Azzam, Eunice Y. Lee, David J. H. F. Knapp, Ying Tan, Ming Fa, Tudor A. Fulga

Source: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b30571d62f584df9bcba980fa93d1565

Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors

Authors: Toni A. Baeumler, Ahmed Ashour Ahmed, Tudor A. Fulga

Source: Cell Reports, Vol 20, Iss 11, Pp 2639-2653 (2017)

Subject Terms: synthetic receptors, chimeric receptors, CRISPR, dCas9-VP64, split Cas9, GPCR, RTK, genome engineering, dCas9-synR, transcriptional programs, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221112471731152X; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/52f0672a227e47cc8af10d1cfe29b3e0

Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development

Authors: Tom J. Phillips, Hannah Scott, David A. Menassa, Ashleigh L. Bignell, Aman Sood, Jude S. Morton, Takami Akagi, Koki Azuma, Mark F. Rogers, Catherine E. Gilmore, Gareth J. Inman, Simon Grant, Yealin Chung, Mais M. Aljunaidy, Christy-Lynn Cooke, Bruno R. Steinkraus, Andrew Pocklington, Angela Logan, Gavin P. Collett, Helena Kemp, Peter A. Holmans, Michael P. Murphy, Tudor A. Fulga, Andrew M. Coney, Mitsuru Akashi, Sandra T. Davidge, C. Patrick Case

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/b061c7fc2e2040a6b274efd65f22ba8a

Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

Authors: Quentin R. V. Ferry, Radostina Lyutova, Tudor A. Fulga

Source: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c2

MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells.

Authors: Bruno Mugat, Abdou Akkouche, Vincent Serrano, Claudia Armenise, Blaise Li, Christine Brun, Tudor A Fulga, David Van Vactor, Alain Pélisson, Séverine Chambeyron

Source: PLoS Genetics, Vol 11, Iss 5, p e1005194 (2015)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4451950?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/fdfe3febb61a42029693c27cbaa78fbf

miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons.

Authors: Manavendra Pathania, Juan Torres-Reveron, Lily Yan, Tomoki Kimura, Tiffany V Lin, Valerie Gordon, Zhao-Qian Teng, Xinyu Zhao, Tudor A Fulga, David Van Vactor, Angélique Bordey

Source: PLoS ONE, Vol 7, Iss 5, p e38174 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3364964?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a26b8ddce4cd42a796ec90b57fecf1b5

Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo.

Authors: Vikram Khurana, Ilan Elson-Schwab, Tudor A Fulga, Katherine A Sharp, Carin A Loewen, Erin Mulkearns, Jaana Tyynelä, Clemens R Scherzer, Mel B Feany

Source: PLoS Genetics, Vol 6, Iss 7, p e1001026 (2010)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2904797?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/aac121ca1623427eb049dd57cbdfc71c

Modeling spinal muscular atrophy in Drosophila.

Authors: Howard Chia-Hao Chang, Douglas N Dimlich, Takakazu Yokokura, Ashim Mukherjee, Mark W Kankel, Anindya Sen, Vasanthi Sridhar, Tudor A Fulga, Anne C Hart, David Van Vactor, Spyros Artavanis-Tsakonas

Source: PLoS ONE, Vol 3, Iss 9, p e3209 (2008)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18791638/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dafc3ca54a234f99bc04d8a718fc5c1a