T cell immunity and the etiology and pathogenesis of preeclampsia

Authors: Saito, Shigeru, Tsuda, Sayaka, Nakashima, Akitoshi

Source: In Journal of Reproductive Immunology September 2023 159

Dynamics of neuropilin1 (Nrp1)-positive thymus-derived and Nrp1-negative peripherally induced paternal antigen specific regulatory T cells in the uterus and spleen during pregnancy in mice

Authors: Araishi, Kohei, Shima, Tomoko, Yasuda, Ippei, Tsuda, Sayaka, Morita, Keiko, Yamaki-Ushijima, Akemi, Nakashima, Akitoshi, Saito, Shigeru

Source: In Journal of Reproductive Immunology February 2023 155

Chloroquine is a safe autophagy inhibitor for sustaining the expression of antioxidant enzymes in trophoblasts

Authors: Furuta, Atsushi, Shima, Tomoko, Yoshida-Kawaguchi, Mihoko, Yamada, Kiyotaka, Yasuda, Ippei, Tsuda, Sayaka, Yamaki-Ushijima, Akemi, Yoneda, Satoshi, Higashisaka, Kazuma, Cheng, Shi-Bin, Matsumoto, Kenji, Tsutsumi, Yasuo, Sharma, Surendra, Saito, Shigeru, Nakashima, Akitoshi

Source: In Journal of Reproductive Immunology February 2023 155

Probiotics including Clostridium butyricum, Enterococcus faecium, and Bacillus subtilis may prevent recurrent spontaneous preterm delivery

Authors: Arai, Eri N., Yoneda, Satoshi, Yoneda, Noriko, Ito, Mika, Tsuda, Sayaka, Shiozaki, Arihiro, Nohira, Tomoyoshi, Hyodo, Hironobu, Kumazawa, Kazumasa, Suzuki, Tomo, Nagasaki, Sumito, Makino, Shintaro, Saito, Shigeru

Source: Journal of obstetrics and gynaecology research. 48(3):688-693

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151863855.0x000001&indx=1&recIds=ETOCvdc_100151863855.0x000001

The role of decidual regulatory T cells in the induction and maintenance of fetal antigen-specific tolerance: Imbalance between regulatory and cytotoxic T cells in pregnancy complications

Authors: Tsuda, Sayaka, Nakashima, Akitoshi, Morita, Keiko, Shima, Tomoko, Yoneda, Satoshi, Kishi, Hiroyuki, Saito, Shigeru

Source: In Human Immunology May 2021 82(5):346-352

Molecular and immunological developments in placentas

Authors: Nakashima, Akitoshi, Shima, Tomoko, Aoki, Aiko, Kawaguchi, Mihoko, Yasuda, Ippei, Tsuda, Sayaka, Yoneda, Satoshi, Yamaki-Ushijima, Akemi, Cheng, Shi-Bin, Sharma, Surendra, Saito, Shigeru

Source: In Human Immunology May 2021 82(5):317-324

Uterine CD11c+ cells induce the development of paternal antigen-specific Tregs via seminal plasma priming

Authors: Shima, Tomoko, Nakashima, Akitoshi, Yasuda, Ippei, Ushijima, Akemi, Inada, Kumiko, Tsuda, Sayaka, Yoshino, Osamu, Tomura, Michio, Saito, Shigeru ^*

Source: In Journal of Reproductive Immunology September 2020 141

Decreased paternal/fetal antigen-specific Treg cells are involved in the pathogenesis of preeclampsia, and decreased Treg cells pool are involved in the pathogenesis of miscarriage

Authors: Saito, Shigeru, Tsuda, Sayaka, Morita, Keiko, Nakashima, Akitoshi

Source: Journal of reproductive immunology. 156

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185903937.0x000001&indx=1&recIds=ETOCvdc_100185903937.0x000001

Development of an in vitro preeclampsia model in the villous tissue using an autophagy inhibitor, Bafilomycin

Authors: Furuta, Atsushi, Yamada, Kiyotaka, Yoshida, Mihoko, Yamaki, Akemi, Yasuda, Ippei, Tsuda, Sayaka, Shima, Tomoko, Yoneda, Satoshi, Nakashima, Akitoshi

Source: Journal of reproductive immunology. 156

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185903735.0x000001&indx=1&recIds=ETOCvdc_100185903735.0x000001

Placental autophagy failure: A risk factor for preeclampsia

Authors: Nakashima, Akitoshi, Shima, Tomoko, Aoki, Aiko, Kawaguchi, Mihoko, Yasuda, Ippei, Tsuda, Sayaka, Yoneda, Satoshi, Yamaki‐Ushijima, Akemi, Cheng, Shibin, Sharma, Surendra, Saito, Shigeru

Source: Journal of obstetrics and gynaecology research. 46(12):2497-2504

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111884611.0x000001&indx=1&recIds=ETOCvdc_100111884611.0x000001

Pre-conception status, obstetric outcome and use of medications during pregnancy of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) in Japan: Multi-center retrospective descriptive study

Authors: Tsuda, Sayaka, Sameshima, Azusa, Sekine, Michikazu, Kawaguchi, Haruna, Fujita, Daisuke, Makino, Shintaro, Morinobu, Akio, Murakawa, Yohko, Matsui, Kiyoshi, Sugiyama, Takao, Watanabe, Mamoru, Suzuki, Yasuo, Nagahori, Masakazu, Murashima, Atsuko, Atsumi, Tatsuya, Oku, Kenji, Mitsuda, Nobuaki, Takei, Syuji, Miyamae, Takako, Takahashi, Naoto, Nakajima, Ken, Saito, Shigeru

Source: Modern rheumatology. 30(5):852-861

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110734419.0x000001&indx=1&recIds=ETOCvdc_100110734419.0x000001

Autophagy is a new protective mechanism against the cytotoxicity of platinum nanoparticles in human trophoblasts

Authors: Nakashima, Akitoshi, Higashisaka, Kazuma, Kusabiraki, Tae, Aoki, Aiko, Ushijima, Akemi, Ono, Yosuke, Tsuda, Sayaka, Shima, Tomoko, Yoshino, Osamu, Nagano, Kazuya, Yoshioka, Yasuo, Tsutsumi, Yasuo, Saito, Shigeru

Source: Scientific reports. 9(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129214554.0x000001&indx=1&recIds=ETOCvdc_100129214554.0x000001

Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts

Authors: Nakashima, Akitoshi, Cheng, Shi-Bin, Kusabiraki, Tae, Motomura, Kenichiro, Aoki, Aiko, Ushijima, Akemi, Ono, Yosuke, Tsuda, Sayaka, Shima, Tomoko, Yoshino, Osamu, Sago, Haruhiko, Matsumoto, Kenji, Sharma, Surendra, Saito, Shigeru

Source: Scientific reports. 9(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189206421.0x000001&indx=1&recIds=ETOCvdc_100189206421.0x000001

Challenges in elucidating the mechanisms of fetal recognition and tolerance by T cells

Authors: Tsuda, Sayaka

Source: Journal of reproductive immunology. 153

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163901173.0x000001&indx=1&recIds=ETOCvdc_100163901173.0x000001

Immunological regulation and the role of autophagy in preeclampsia.

Authors: Nakashima, Akitoshi, Furuta, Atsushi, Yoshida‐Kawaguchi, Mihoko, Yamada, Kiyotaka, Nunomura, Haruka, Morita, Keiko, Yasuda, Ippei, Yoneda, Satoshi, Yamaki‐Ushijima, Akemi, Shima, Tomoko, Tsuda, Sayaka

Source: American Journal of Reproductive Immunology; Mar2024, Vol. 91 Issue 3, p1-10, 10p

Subject Terms: REGULATORY T cells, AUTOPHAGY, PREECLAMPSIA, T cell receptors, IMMUNOSUPPRESSION

Peripherally induced paternal antigen-specific Treg cells proliferate at the implantation site in allogeneic pregnant mice

Authors: Araishi, Kohei, Shima, Tomoko, Yasuda, Ippei, Yamaki-Ushijima, Akemi, Morita, Keiko, Tsuda, Sayaka, Saito, Shigeru, Nakashima, Akitoshi

Source: Journal of reproductive immunology. 148

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162738088.0x000001&indx=1&recIds=ETOCvdc_100162738088.0x000001

O5-1 - Development of an in vitro preeclampsia model in the villous tissue using an autophagy inhibitor, Bafilomycin

Authors: Furuta, Atsushi, Yamada, Kiyotaka, Yoshida, Mihoko, Yamaki, Akemi, Yasuda, Ippei, Tsuda, Sayaka, Shima, Tomoko, Yoneda, Satoshi, Nakashima, Akitoshi

Source: In Journal of Reproductive Immunology March 2023 156

OL - Decreased paternal/fetal antigen-specific Treg cells are involved in the pathogenesis of preeclampsia, and decreased Treg cells pool are involved in the pathogenesis of miscarriage

Authors: Saito, Shigeru, Tsuda, Sayaka, Morita, Keiko, Nakashima, Akitoshi

Source: In Journal of Reproductive Immunology March 2023 156

TCR repertoire analysis reveals the immunological difference between pregnancy and cancer

Authors: Morita, Keiko, Tsuda, Sayaka, Tsuda, Kei, Shima, Tomoko, Nakashima, Akitoshi, Saito, Shigeru

Source: Journal of reproductive immunology. 142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100119185205.0x000001&indx=1&recIds=ETOCvdc_100119185205.0x000001

Symposium 2-2 - Challenges in elucidating the mechanisms of fetal recognition and tolerance by T cells

Authors: Tsuda, Sayaka

Source: In Journal of Reproductive Immunology September 2022 153