Blood-based biomarkers in patients with non-small cell lung cancer treated with immune checkpoint blockade.

Authors: Tsai, Yo-Ting¹ (AUTHOR), Schlom, Jeffrey¹ (AUTHOR) schlomj@mail.nih.gov, Donahue, Renee N.¹ (AUTHOR)

Source: Journal of Experimental & Clinical Cancer Research (17569966). 3/16/2024, Vol. 43 Issue 1, p1-22. 22p.

Subject Terms: *NON-small-cell lung carcinoma, *IMMUNE checkpoint proteins, *CIRCULATING tumor DNA, *IMMUNE checkpoint inhibitors, *BIOMARKERS

PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia

Authors: Goswami, Swagata, Mani, Rajeswaran, Nunes, Jessica, Chiang, Chi-Ling, Zapolnik, Kevan, Hu, Eileen, Frissora, Frank, Mo, Xiaokui, Walker, Logan A., Yan, Pearlly, Bundschuh, Ralf, Beaver, Larry, Devine, Raymond, Tsai, Yo-Ting, Ventura, Ann, Xie, Zhiliang, Chen, Min, Lapalombella, Rosa, Walker, Alison, Mims, Alice, Larkin, Karilyn, Grieselhuber, Nicole, Bennett, Chad, Phelps, Mitch, Hertlein, Erin, Behbehani, Gregory, Vasu, Sumithira, Byrd, John C., Muthusamy, Natarajan

Source: Blood. 139(9):1340-1358

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183245068.0x000001&indx=1&recIds=ETOCvdc_100183245068.0x000001

BRAFV600E accelerates disease progression and enhances immune suppression in a mouse model of B-cell leukemia

Authors: Tsai, Yo-Ting ^{1, *}, Lakshmanan, Aparna ^{1, *}, Lehman, Amy ², Harrington, Bonnie K. ³, Lucas, Fabienne McClanahan ¹, Tran, Minh ¹, Sass, Ellen J. ¹, Long, Meixiao ¹, Flechtner, Alan D. ³, Jaynes, Florinda ³, La Perle, Krista ^{1, 3}, Coppola, Vincenzo ¹, Lozanski, Gerard ⁴, Muthusamy, Natarajan ^{1, 3}, Byrd, John C. ^{1, 3}, Grever, Michael R. ¹, Lucas, David M. ^{1, *}

Source: In Blood Advances 14 November 2017 1(24):2147-2160

BRAFV600E induces ABCB1/P-glycoprotein expression and drug resistance in B-cells via AP-1 activation

Authors: Tsai, Yo-Ting, Lozanski, Gerard, Lehman, Amy, Sass, Ellen J., Hertlein, Erin, Salunke, Santosh B., Chen, Ching-Shih, Grever, Michael R., Byrd, John C., Lucas, David M.

Source: In Leukemia Research November 2015 39(11):1270-1277

Deregulation of p53 and RB Transcriptional Control Leads to Overexpression of DNA Methyltransferases in Lung Cancer

Authors: Tang, Yen-An, Tsai, Yo-Ting, Lin, Ruo-Kai, Hsu, Han-Shui, Chen, Chih-Yi, Wang, Yi-Ching

Source: In Journal of Cancer Research and Practice June 2014 1(1):14-27

A T cell receptor β chain–directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity.

Authors: Hsu, Jonathan, Donahue, Renee N., Katragadda, Madan, Lowry, Jessica, Huang, Wei, Srinivasan, Karunya, Guntas, Gurkan, Tang, Jian, Servattalab, Roya, Moisan, Jacques, Tsai, Yo-Ting, Stoop, Allart, Palakurthi, Sangeetha, Chopra, Raj, Liu, Ke, Wherry, E. John, Su, Zhen, Gulley, James L., Bayliffe, Andrew, Schlom, Jeffrey

Source: Science Translational Medicine; 11/29/2023, Vol. 15 Issue 724, p1-18, 18p

Subject Terms: T cell receptors, T cells, T-cell exhaustion, ANTINEOPLASTIC agents, CYTOKINE receptors, GENE silencing

Phase I Trial of a Modified Vaccinia Ankara Priming Vaccine Followed by a Fowlpox Virus Boosting Vaccine Modified to Express Brachyury and Costimulatory Molecules in Advanced Solid Tumors

Authors: Collins, Julie M., Donahue, Renee N., Tsai, Yo‐Ting, Manu, Michell, Palena, Claudia, Gatti‐Mays, Margaret E., Marté, Jennifer L., Madan, Ravi A., Karzai, Fatima, Heery, Christopher R., Strauss, Julius, Abdul‐Sater, Houssein, Cordes, Lisa, Schlom, Jeffrey, Gulley, James L., Bilusic, Marijo

Source: Oncologist. 25(7):560-e1006

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100119672479.0x000001&indx=1&recIds=ETOCvdc_100119672479.0x000001

Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10

Authors: Wu, Ming-Hsun, Tsai, Yo-Ting, Hua, Kuo-Tai, Chang, Kun-Che, Kuo, Min-Liang, Lin, Ming-Tsan

Source: In The Journal of Nutritional Biochemistry November 2012 23(11):1434-1439

Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma

Authors: Rajan, Arun, Heery, Christopher R., Thomas, Anish, Mammen, Andrew L., Perry, Susan, O'Sullivan Coyne, Geraldine, Guha, Udayan, Berman, Arlene, Szabo, Eva, Madan, Ravi A., Ballester, Leomar Y., Pittaluga, Stefania, Donahue, Renee N., Tsai, Yo-Ting, Lepone, Lauren M., Chin, Kevin, Ginty, Fiona, Sood, Anup, Hewitt, Stephen M., Schlom, Jeffrey, Hassan, Raffit, Gulley, James L.

Source: Journal for immunotherapy of cancer. 7(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130994881.0x000001&indx=1&recIds=ETOCvdc_100130994881.0x000001

Undecylprodigiosin selectively induces apoptosis in human breast carcinoma cells independent of p53

Authors: Ho, Tsing-Fen, Ma, Chieh-Ju, Lu, Chien-Hsing, Tsai, Yo-Ting, Wei, Yu-Hong, Chang, Jo-Shu, Lai, Jun-Kai, Cheuh, Pin-Ju, Yeh, Chi-Tai, Tang, Pin-Chi, Tsai Chang, Jinghua, Ko, Jiunn-Liang, Liu, Fu-Shing, Yen, Hungchen E., Chang, Chia-Che

Source: In Toxicology and Applied Pharmacology 2007 225(3):318-328

Joint-Predominant Rheumatic Complications of Immune Checkpoint Inhibitor Therapy in Patients with Thymic Epithelial Tumors.

Authors: Mullenix, Cristina, Ballman, Madison, Chen, Haobin, Swift, Shannon, McAdams, Meredith J, Tsai, Yo-Ting, Donahue, Renee N, Poretta, Trina, Gupta, Sarthak, Loehrer, Patrick J, Schlom, Jeffrey, Gulley, James L, Rajan, Arun

Source: Oncologist; Apr2022, Vol. 27 Issue 4, pe353-e356, 4p, 2 Charts

Subject Terms: ADVERSE health care events, EPITHELIAL cell tumors, IMMUNE checkpoint inhibitors, INFECTIOUS arthritis, JOINT diseases, RISK assessment, CANCER patients, POLYMYALGIA rheumatica, RHEUMATISM, MYOSITIS, IMMUNOTHERAPY, DISEASE risk factors

Randomized Phase II Trial of mFOLFOX6 + Bevacizumab Alone or with AdCEA Vaccine + Avelumab Immunotherapy for Untreated Metastatic Colorectal Cancer.

Authors: Redman, Jason M, Tsai, Yo-Ting, Weinberg, Benjamin A, Donahue, Renee N, Gandhy, Shruti, Gatti-Mays, Margaret E, Sater, Houssein Abdul, Bilusic, Marijo, Cordes, Lisa M, Steinberg, Seth M, Marte, Jennifer L, Jochems, Caroline, Kim, Sunnie S, Marshall, John L, McMahon, Sheri, Redmond, Erica, Schlom, Jeffrey, Gulley, James L, Strauss, Julius

Source: Oncologist; Mar2022, Vol. 27 Issue 3, p198-209, 12p, 1 Diagram, 4 Charts, 3 Graphs

Subject Terms: CONFIDENCE intervals, CANCER chemotherapy, METASTASIS, MONOCLONAL antibodies, COLORECTAL cancer, RANDOMIZED controlled trials, BEVACIZUMAB, CANCER vaccines, STATISTICAL sampling, PROGRESSION-free survival, IMMUNOTHERAPY

This result is not displayed to guests.
Login for full access.

Preliminary efficacy, safety, and immunomodulatory effects of PT-112 from a phase 2 proof of concept study in patients (pts) with thymic epithelial tumors (TETs).

Authors: McAdams, Meredith, Swift, Shannon, Donahue, Renee N., Celades, Carolina, Tsai, Yo-Ting, Bingham, Molly, Szabo, Eva, Zhao, Chen, Sansone, Susan, Choradia, Nirmal, Shelat, Meenakshi, O'Donnell, Joseph Francis, Ames, Tyler David, Raphael, Brooke, Steinberg, Seth M., Gulley, James L., Schlom, Jeffrey, Rajan, Arun

Source: Journal of Clinical Oncology; 2023 Supplement 16, Vol. 41, pe20647-e20647, 1p

BRAFV600Eaccelerates disease progression and enhances immune suppression in a mouse model of B-cell leukemia

Authors: Tsai, Yo-Ting, Lakshmanan, Aparna, Lehman, Amy, Harrington, Bonnie K., Lucas, Fabienne McClanahan, Tran, Minh, Sass, Ellen J., Long, Meixiao, Flechtner, Alan D., Jaynes, Florinda, La Perle, Krista, Coppola, Vincenzo, Lozanski, Gerard, Muthusamy, Natarajan, Byrd, John C., Grever, Michael R., Lucas, David M.

Source: Blood Advances; November 2017, Vol. 1 Issue: 24 p2147-2160, 14p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

BRAFV600EAccelerates Disease Progression and Increases Immune Suppression in a Mouse Model of B-Cell Leukemia

Authors: Tsai, Yo-Ting, Lakshmanan, Aparna, Lehman, Amy M., Sass, Ellen J., Tran, Minh, McClanahan, Fabienne, Long, Meixiao, Harrington, Bonnie K., La Perle, Krista, Coppola, Vincenzo, Lozanski, Gerard, Muthusamy, Natarajan, Byrd, John C., Grever, Michael R., Lucas, David M.

Source: Blood; January 2016, Vol. 128 Issue: 22 p1206-1206, 1p