Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma

Authors: Ligtenberg, Maarten A., Pico de Coaña, Yago, Shmushkovich, Taisia, Yoshimoto, Yuya, Truxova, Iva, Yang, Yuan, Betancur-Boissel, Monica, Eliseev, Alexey V., Wolfson, Alexey D., Kiessling, Rolf

Source: In Molecular Therapy 6 June 2018 26(6):1482-1493

Relevance of the chaperone-like protein calreticulin for the biological behavior and clinical outcome of cancer

Authors: Fucikova, Jitka, Kasikova, Lenka, Truxova, Iva, Laco, Jan, Skapa, Petr, Ryska, Ales, Spisek, Radek

Source: In Immunology Letters January 2018 193:25-34

A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer

Authors: D'Amico, Lucia, Menzel, Ulrike, Prummer, Michael, Müller, Philipp, Buchi, Mélanie, Kashyap, Abhishek, Haessler, Ulrike, Yermanos, Alexander, Gébleux, Rémy, Briendl, Manfred, Hell, Tamara, Wolter, Fabian, Beerli, Roger, Truxova, Iva, Radek, Špíšek, Vlajnic, Tatjana, Grawunder, Ulf, Reddy, Sai, Zippelius, Alfred

Source: Journal for immunotherapy of cancer. 7(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186496728.0x000001&indx=1&recIds=ETOCvdc_100186496728.0x000001

Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients

Authors: Truxova, Iva, Kasikova, Lenka, Hensler, Michal, Skapa, Petr, Laco, Jan, Pecen, Ladislav, Belicova, Lucie, Praznovec, Ivan, Halaska, Michael, Brtnicky, Tomas, Salkova, Eva, Rob, Lukas, Kodet, Roman, Goc, Jeremy, Sautes-Fridman, Catherine, Fridman, Wolf, Ryska, Ales, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka

Source: Journal for immunotherapy of cancer. 6(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185348978.0x000001&indx=1&recIds=ETOCvdc_100185348978.0x000001

Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

Authors: Fucikova, Jitka ^*, Truxova, Iva ^*, Hensler, Michal, Becht, Etienne, Kasikova, Lenka, Moserova, Irena, Vosahlikova, Sarka, Klouckova, Jana, Church, Sarah E., Cremer, Isabelle, Kepp, Oliver, Kroemer, Guido, Galluzzi, Lorenzo, Salek, Cyril, Spisek, Radek

Source: In Blood 29 December 2016 128(26):3113-3124

Type I interferon and cancer.

Authors: Holicek, Peter, Guilbaud, Emma, Klapp, Vanessa, Truxova, Iva, Spisek, Radek, Galluzzi, Lorenzo, Fucikova, Jitka

Source: Immunological Reviews; Jan2024, Vol. 321 Issue 1, p115-127, 13p

Subject Terms: TYPE I interferons, IMMUNE checkpoint inhibitors, CANCER cells, CANCER invasiveness, CELL death

Day 3 Poly (I:C)-activated dendritic cells generated in CellGro for use in cancer immunotherapy trials are fully comparable to standard Day 5 DCs

Authors: Truxova, Iva, Pokorna, Katerina, Kloudova, Kamila, Partlova, Simona, Spisek, Radek, Fucikova, Jitka

Source: In Immunology Letters July 2014 160(1):39-49

Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients

Authors: Kasikova, Lenka, Hensler, Michal, Truxova, Iva, Skapa, Petr, Laco, Jan, Belicova, Lucie, Praznovec, Ivan, Vosahlikova, Sarka, Halaska, Michael J., Brtnicky, Tomas, Rob, Lukas, Presl, Jiri, Kostun, Jan, Cremer, Isabelle, Ryska, Ales, Kroemer, Guido, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka

Source: Journal for immunotherapy of cancer. 7(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130994412.0x000001&indx=1&recIds=ETOCvdc_100130994412.0x000001

Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients.

Authors: Holicek, Peter, Truxova, Iva, Rakova, Jana, Salek, Cyril, Hensler, Michal, Kovar, Marek, Reinis, Milan, Mikyskova, Romana, Pasulka, Josef, Vosahlikova, Sarka, Remesova, Hana, Valentova, Iva, Lysak, Daniel, Holubova, Monika, Kaspar, Petr, Prochazka, Jan, Kasikova, Lenka, Spisek, Radek, Galluzzi, Lorenzo, Fucikova, Jitka

Source: Cell Death & Disease; Mar2023, Vol. 14 Issue 3, p1-12, 12p

Chapter Two - Side-by-side comparison of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death

Authors: Kasikova, Lenka, Truxova, Iva, Cremer, Isabelle, Sautes-Fridman, Catherine, Kepp, Oliver, Kroemer, Guido, Spisek, Radek, Fucikova, Jitka ^*

Source: In Methods in Enzymology 2020 632:15-25

Chapter Fourteen - Assessment of NK cell-mediated cytotoxicity by flow cytometry after rapid, high-yield isolation from peripheral blood

Authors: Holicek, Peter, Truxova, Iva, Kasikova, Lenka, Vosahlikova, Sarka, Salek, Cyril, Rakova, Jana, Holubova, Monika, Lysak, Daniel, Cremer, Isabelle, Spisek, Radek, Fucikova, Jitka ^*

Source: In Methods in Enzymology 2020 631:277-287

Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death

Authors: Moserova, Irena, Truxova, Iva, Garg, Abhishek D., Tomala, Jakub, Agostinis, Patrizia, Cartron, Pierre Francois, Vosahlikova, Sarka, Kovar, Marek, Spisek, Radek, Fucikova, Jitka

Source: Oncoimmunology. 6(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100056843738.0x000001&indx=1&recIds=ETOCvdc_100056843738.0x000001

Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure inhibit prostate tumor growth in TRAMP mice

Authors: Mikyskova, Romana, Indrova, Marie, Stepanek, Ivan, Kanchev, Ivan, Bieblova, Jana, Vosahlikova, Sarka, Moserova, Irena, Truxova, Iva, Fucikova, Jitka, Bartunkova, Jirina, Spisek, Radek, Sedlacek, Radislav, Reinis, Milan

Source: Oncoimmunology. 6(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100056125810.0x000001&indx=1&recIds=ETOCvdc_100056125810.0x000001

TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients.

Authors: Rakova, Jana¹, Truxova, Iva¹, Holicek, Peter^1,2, Salek, Cyril^3,4, Hensler, Michal¹, Kasikova, Lenka¹, Pasulka, Josef¹, Holubova, Monika⁵, Kovar, Marek⁶, Lysak, Daniel⁷, Kline, Justin P.⁸, Racil, Zdenek^3,4, Galluzzi, Lorenzo^{9,10,11,12,13}, Spisek, Radek^1,2, Fucikova, Jitka^1,2 fucikova@sotio.com

Source: OncoImmunology. 2021, Vol. 10 Issue 1, p1-12. 12p.

Subject Terms: *KILLER cells, *HEPATITIS A virus cellular receptors, *CYTOTOXIC T cells, *ACUTE myeloid leukemia, *IMMUNE checkpoint inhibitors

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