Strategy for modeling higher-order G-quadruplex structures recalcitrant to NMR determination

Authors: Michael Sabo, T., Trent, John O., Chaires, Jonathan B., Monsen, Robert C.

Source: In Methods October 2024 230:9-20

G-quadruplex DNA: A Longer Story

Authors: Monsen, Robert C., Trent, John O., Chaires, Jonathan B.

Source: Accounts of chemical research. 55(22):3242-3252

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631199419&indx=1&recIds=ETOCRN631199419

Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells

Authors: Ajayi-Smith, Aderonke, van der Watt, Pauline, Mkwanazi, Nonkululeko, Carden, Sarah, Trent, John O., Leaner, Virna D.

Source: In Experimental Cell Research 15 July 2021 404(2)

Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer

Authors: Khan, Nazimuddin, Shah, Parag P., Ban, David, Trigo-Mouriño, Pablo, Carneiro, Marta G., DeLeeuw, Lynn, Dean, William L., Trent, John O., Beverly, Levi J., Konrad, Manfred, Lee, Donghan, Sabo, T. Michael

Source: In Journal of Biological Chemistry August 2019 294(31):11920-11933

Identification of functional domains of the minor fimbrial antigen involved in the interaction of Porphyromonas gingivalis with oral streptococci

Authors: Roky, Mohammad, Trent, John O., Demuth, Donald R.

Source: Molecular oral microbiology. 35(2):66-77

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106947806.0x000001&indx=1&recIds=ETOCvdc_100106947806.0x000001

Compounds for treating cancer, for administering, and for pharmaceutical compositions

G-quadruplex virtual drug screening: A review

Authors: Monsen, Robert C., Trent, John O.

Source: In Biochimie September 2018 152:134-148

Helix-Stabilized Cyclic Peptides as Selective Inhibitors of Steroid Receptor-Coactivator Interactions

Authors: Leduc, Anne-Marie, Trent, John O., Wittliff, James L., Bramlett, Kelli S., Briggs, Stephen L., Chirgadze, Nikolay Y., Wang, Yong, Burris, Thomas P., Spatola, Arno F.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Sep . 100(20), 11273-11278.

Access URL: https://www.jstor.org/stable/3147781

G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms

Authors: Bates, Paula J., Reyes-Reyes, Elsa M., Malik, Mohammad T., Murphy, Emily M., O'Toole, Martin G., Trent, John O.

Source: In BBA - General Subjects May 2017 1861(5) Part B:1414-1428

Allosteric, Chiral-Selective Drug Binding to DNA

Authors: Qu, Xiaogang, Trent, John O., Fokt, Izabela, Priebe, Waldemar, Chaires, Jonathan B.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2000 Oct . 97(22), 12032-12037.

Access URL: https://www.jstor.org/stable/123785

Release kinetics of paclitaxel and cisplatin from two and three layered gold nanoparticles

Authors: England, Christopher G., Miller, M. Clarke, Kuttan, Ashani, Trent, John O., Frieboes, Hermann B.

Source: In European Journal of Pharmaceutics and Biopharmaceutics May 2015 92:120-129

Folding and Unfolding Pathways of the Human Telomeric G-Quadruplex

Authors: Gray, Robert D., Trent, John O., Chaires, Jonathan B.

Source: In Journal of Molecular Biology 17 April 2014 426(8):1629-1650

Aptamer imaging with Cu-64 labeled AS1411: Preliminary assessment in lung cancer

Authors: Li, Junling, Zheng, Huaiyu, Bates, Paula J., Malik, Tariq, Li, Xiao-Feng, Trent, John O., Ng, Chin K.

Source: In Nuclear Medicine and Biology February 2014 41(2):179-185

Separation of Quadruplex Polymorphism in DNA Sequences by Reversed‐Phase Chromatography

Authors: Miller, M. Clarke, Ohrenberg, Carl J., Kuttan, Ashani, Trent, John O.

Source: Current protocols in nucleic acid chemistry. 61(1):17.7.1-17.7.18

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111790013.0x000001&indx=1&recIds=ETOCvdc_100111790013.0x000001

Evidence for the contribution of non-covalent steroid interactions between DNA and topoisomerase in the genotoxicity of steroids

Authors: Snyder, Ronald D., Holt, Patrick A., Maguire, Jon M., Trent, John O.

Source: Drug and chemical toxicology. 38(2):212-219

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105355156.0x000001&indx=1&recIds=ETOCvdc_100105355156.0x000001

Small molecule inhibitors of PFKFB3 and glycolytic flux and their methods of use as anti-cancer therapeutics

Iodo pyrimidine derivatives useful for the treatment of macrophage migration inhibitory factor (MIF)-implicated diseases and conditions

Methods and compositions for modulating ocular damage

Macrophage migration inhibitory factor antagonists and methods of using same

Compounds for treating disease, for administering, and for pharmaceutical compositions