Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics

Authors: BingBing Li, Cheng Zhang, XiaoJuan Xu, QiQin Shen, ShuNan Luo, JunFeng Hu

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: osteosarcoma, cGAS-STING, treatment target, drug, tumor immunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1539396/full; https://doaj.org/toc/1664-3224

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Effectiveness in root canal disinfection and biocompatibility of a final in vitro irrigation protocol based on cellulases and a hyperosmotic solution

Authors: Velázquez-Moreno, Selene ^a, Zavala-Alonso, Norma V. ^b, Rodríguez, Ricardo Oliva ^c, Sánchez, Roberto Sánchez ^d, Morales, Carlos Martín Torre ^d, Gonzalez-Ortega, Omar ^{a, e}, Martinez-Gutierrez, Fidel ^{a, e, 1, ⁎}

Source: In Archives of Oral Biology March 2025 171

circFOXP1: a potential diagnostic and therapeutic target in human diseases

Authors: Qiang Yi, Xinting Ouyang, Kui Zhong, Zheng Chen, Weijian Zhu, Gangfeng Zhu, Jinghua Zhong

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: circRNA, circFOXP1, molecular mechanisms, biomarker, treatment target, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1489378/full; https://doaj.org/toc/1664-3224

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Potentials of ribosomopathy gene as pharmaceutical targets for cancer treatment

Authors: Mengxin Wang, Stephen Vulcano, Changlu Xu, Renjian Xie, Weijie Peng, Jie Wang, Qiaojun Liu, Lee Jia, Zhi Li, Yumei Li

Source: Journal of Pharmaceutical Analysis, Vol 14, Iss 3, Pp 308-320 (2024)

Subject Terms: Ribosome biogenesis, Ribosomopathy gene, Cancer treatment target, Pharmaceutical target, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095177923002599; https://doaj.org/toc/2095-1779

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Identification of neutrophil extracellular trap-driven gastric cancer heterogeneity and C5AR1 as a therapeutic target

Authors: Zhao Jing, Li Xiangyu, Li Liming, Chen Beibei, Xu Weifeng, He Yunduan, Chen Xiaobing

Source: Acta Biochimica et Biophysica Sinica, Vol 56, Pp 538-550 (2024)

Subject Terms: neutrophil extracellular trap, gastric cancer, heterogeneity, personalized therapy, C5AR1, treatment target, Biochemistry, QD415-436, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1672-9145

Access URL: https://doaj.org/article/e706bb6f2d154511a81e3341a4e7efa0

Implication of Ferroptosis in Cholangiocarcinoma: A Potential Future Target?

Authors: Yang M, Li M, Lyu Z, Yang Z

Source: Cancer Management and Research, Vol Volume 15, Pp 335-342 (2023)

Subject Terms: cholangiocarcinoma, ferroptosis, inflammation, iron metabolism, treatment target, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.dovepress.com/implication-of-ferroptosis-in-cholangiocarcinoma-a-potential-future-ta-peer-reviewed-fulltext-article-CMAR; https://doaj.org/toc/1179-1322

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Endo-Lysosomal and Autophagy Pathway and Ubiquitin-Proteasome System in Mood Disorders: A Review Article

Authors: Matutino Santos P, Pereira Campos G, Nascimento C

Source: Neuropsychiatric Disease and Treatment, Vol Volume 19, Pp 133-151 (2023)

Subject Terms: mood disorders, endo-lysosomal pathway, ubiquitin-proteasome system, autophagy, endo-lysosome, neuroplasticity, novel treatments, treatment target, translational science, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.dovepress.com/endo-lysosomal-and-autophagy-pathway-and-ubiquitin-proteasome-system-i-peer-reviewed-fulltext-article-NDT; https://doaj.org/toc/1178-2021

Access URL: https://doaj.org/article/08739d5a220e42b0bdd9d9a4259ccad0

Effectiveness of early glucocorticoids in myasthenia gravis: a retrospective cohort study

Authors: Lulu Zhen, Xue Zhao, Wenbo Li, Jinru Wu, Haodong Shang, Shufan Chen, Xiaoyan Zhu, Yiren Wang, Xiaoxiao Yu, Guanlian Hu, Zhan Sun, Yingna Zhang, Jing Zhang, Hua Fang, Yunke Zhang, Qingyong Zhang, Xinzheng Cui, Jie Lv, Junhong Yang, Feng Gao

Source: Frontiers in Neurology, Vol 14 (2023)

Subject Terms: myasthenia gravis, glucocorticoids, early treatment with GC, delayed treatment with GC, treatment target, prognostic factors, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2023.1259484/full; https://doaj.org/toc/1664-2295

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Exploration in the Therapeutic and Multi-Target Mechanism of Ketamine on Cerebral Ischemia Based on Network Pharmacology and Molecular Docking

Authors: Xiong L, Liu SC, Huo SY, Pu LQ, Li JJ, Bai WY, Yang Y, Shao JL

Source: International Journal of General Medicine, Vol Volume 15, Pp 4195-4208 (2022)

Subject Terms: ketamine；cerebral ischemia；treatment target；network pharmacology, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/exploration-in-the-therapeutic-and-multi-target-mechanism-of-ketamine--peer-reviewed-fulltext-article-IJGM; https://doaj.org/toc/1178-7074

Access URL: https://doaj.org/article/f09a62c9079b4256bec5815452674c77

Corrigendum: Endoplasmic reticulum stress of gut enterocyte and intestinal diseases

Authors: Han Gao, Chengwei He, Rongxuan Hua, Yuexin Guo, Boya Wang, Chen Liang, Lei Gao, Hongwei Shang, Jing-Dong Xu

Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

Subject Terms: endoplasmic reticulum stress, unfolded protein response, cell death, colon cancer, treatment target, inflammatory bowel disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.1051738/full; https://doaj.org/toc/2296-889X

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The dual function of microglial polarization and its treatment targets in ischemic stroke

Authors: Yong Mo, Weilin Xu, Kaijing Fu, Hainan Chen, Jing Wen, Qianrong Huang, Fangzhou Guo, Ligen Mo, Jun Yan

Source: Frontiers in Neurology, Vol 13 (2022)

Subject Terms: ischemic stroke, treatment target, microglia, polarization, dual function, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2022.921705/full; https://doaj.org/toc/1664-2295

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Tumor acidity: From hallmark of cancer to target of treatment

Authors: Alexey Bogdanov, Andrey Bogdanov, Viacheslav Chubenko, Nikita Volkov, Fedor Moiseenko, Vladimir Moiseyenko

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: cancer, metabolism, acidity, hallmark, treatment target, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.979154/full; https://doaj.org/toc/2234-943X

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Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression

Authors: Ya Fan, Jia Wang, Yuemei Xu, Yipin Wang, Tao Song, Xiubin Liang, Feng Jin, Dongming Su

Source: Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-14 (2021)

Subject Terms: Anti-warburg effect, Cancer progression, Molecular patterns, Treatment target, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/b4ee6e0262564d5b9e05ecdd2de015f2

Editorial: Extracellular Vesicles: From Characterization to Treatment

Authors: Xinlei Li, Jeffrey David Galley

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: extracellular vesicles, diagnostics, treatment target, disease progression, therapeutics, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.945529/full; https://doaj.org/toc/2296-634X

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Endoplasmic Reticulum Stress of Gut Enterocyte and Intestinal Diseases

Authors: Han Gao, Chengwei He, Rongxuan Hua, Yuexin Guo, Boya Wang, Chen Liang, Lei Gao, Hongwei Shang, Jing-Dong Xu

Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

Subject Terms: endoplasmic reticulum stress, unfolded protein response, cell death, colon cancer, treatment target, inflammatory bowel disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.817392/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/3993ed96417e40e884542471a94847bd

Corrigendum: The Function of microRNAs in Pulmonary Embolism: Review and Research Outlook

Authors: Mingyao Luo, Mingyuan Du, Chang Shu, Sheng Liu, Jiehua Li, Lei Zhang, Xin Li

Source: Frontiers in Pharmacology, Vol 12 (2022)

Subject Terms: biomarker, deep venous thrombosis, miRNA, molecular regulation, pulmonary embolism, treatment target, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.822059/full; https://doaj.org/toc/1663-9812

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The Role of Brain-Derived Neurotrophic Factor in Epileptogenesis: an Update

Authors: Xinyi Wang, Zhe Hu, Kai Zhong

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: epilepsy, brain-derived neurotrophic factor, tyrosine kinase receptor B, treatment target, epileptogenesis, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.758232/full; https://doaj.org/toc/1663-9812

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The Function of microRNAs in Pulmonary Embolism: Review and Research Outlook

Authors: Mingyao Luo, Mingyuan Du, Chang Shu, Sheng Liu, Jiehua Li, Lei Zhang, Xin Li

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: miRNA, biomarker, treatment target, pulmonary embolism, deep venous thrombosis, molecular regulation, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.743945/full; https://doaj.org/toc/1663-9812

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Global health policy: Does the 90-90-90 treatment target address the burden of HIV/AIDS?

Authors: Bisrat Asfaw, VE ADAMU

Source: Orapuh Journal, Vol 1, Iss 2 (2020)

Subject Terms: HIV Strategic Plan, 90-90-90 treatment target, Anti-Retroviral Therapy, Internal medicine, RC31-1245, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/article/view/23; https://doaj.org/toc/2644-3740

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Management plans for populations with normal-to-hypertensive blood pressures: risks and benefits of antihypertensive drug treatment in populations previously defined as having high-normal blood pressure

Authors: Sungha Park

Source: The Korean Journal of Internal Medicine, Vol 34, Iss 1, Pp 44-49 (2019)

Subject Terms: blood pressure, hypertension, treatment target, cardiovascular diseases, Medicine

File Description: electronic resource

Relation: http://www.kjim.org/upload/pdf/kjim-2018-382.pdf; https://doaj.org/toc/1226-3303; https://doaj.org/toc/2005-6648

Access URL: https://doaj.org/article/258c3024cc044f268bc8983808087301