BBSome deficiency in Lotmaria passim reveals divergent functions in trypanosomatid parasites.

Authors: Yuan, Xuye¹ (AUTHOR) Xuye.Yuan@xjtlu.edu.cn, Kadowaki, Tatsuhiko¹ (AUTHOR) Tatsuhiko.Kadowaki@xjtlu.edu.cn

Source: Parasites & Vectors. 2/18/2025, Vol. 18 Issue 1, p1-16. 16p.

Subject Terms: *LIPID rafts, *MEMBRANE transport proteins, *HONEYBEES, *LEISHMANIA mexicana, *CYTOLOGY, *DNA repair

Predicting substrates for orphan solute carrier proteins using multi-omics datasets.

Authors: Zhang, Y.¹ (AUTHOR), Newstead, S.^1,2 (AUTHOR), Sarkies, P.¹ (AUTHOR) peter.sarkies@bioch.ox.ac.uk

Source: BMC Genomics. 2/11/2025, Vol. 26, p1-16. 16p.

Subject Terms: *LIFE sciences, *MEMBRANE transport proteins, *COMPUTATIONAL biology, *CARRIER proteins, *CYTOLOGY

The Ferroxidase–Permease System for Transport of Iron Across Membranes: From Yeast to Humans.

Authors: Amadei, Matteo¹ (AUTHOR) matteo.amadei@uniroma1.it, Polticelli, Fabio² (AUTHOR) fabio.polticelli@uniroma3.it, Musci, Giovanni³ (AUTHOR) musci@unimol.it, Bonaccorsi di Patti, Maria Carmela¹ (AUTHOR) mariacarmela.bonaccorsi@uniroma1.it

Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 3, p875. 21p.

Subject Terms: *MULTICOPPER oxidase, *MEMBRANE transport proteins, *COPPER, *OXYGEN in water, *MULTICELLULAR organisms

Identifying optimal substrate classes of membrane transporters.

Authors: Denger, Andreas¹ (AUTHOR), Helms, Volkhard¹ (AUTHOR) volkhard.helms@bioinformatik.uni-saarland.de

Source: PLoS ONE. 12/19/2024, Vol. 19 Issue 12, p1-24. 24p.

Subject Terms: *MEMBRANE transport proteins, *CARRIER proteins, *ESCHERICHIA coli, *SUPERVISED learning, *BIOMOLECULES, *METABOLOMICS

Detection of transmembrane protein 100 in breast cancer: Correlation with malignant progression and chemosensitivity.

Authors: Liu, Xiao¹ (AUTHOR), Zhang, Guiqian² (AUTHOR), Zhao, Ling¹ (AUTHOR) 18560291381@163.com

Source: CytoJournal. 12/18/2024, Vol. 21, p1-12. 12p.

Subject Terms: *MEMBRANE transport proteins, *FLOW cytometry, *IN vitro studies, *DOCETAXEL, *DRUG resistance in cancer cells, *RESEARCH funding, *PHOSPHORYLATION, *BREAST tumors, *POLYMERASE chain reaction, *CELL proliferation, *APOPTOSIS, *DESCRIPTIVE statistics, *CELL motility, *CELLULAR signal transduction, *IMMUNOHISTOCHEMISTRY, *CELL lines, *WESTERN immunoblotting, *STAINS & staining (Microscopy), *TRANSFERASES, *BIOLOGICAL assay, *MOLECULAR biology, *DISEASE progression

Functional Roles of the Charged Residues of the C- and M-Gates in the Yeast Mitochondrial NAD + Transporter Ndt1p.

Authors: Miniero, Daniela Valeria^1,2 (AUTHOR) danielavaleria.miniero@uniba.it, Palmieri, Ferdinando^1,3 (AUTHOR) ferdpalmieri@gmail.com, Quadrotta, Virginia⁴ (AUTHOR) virginia.quadrotta@uniroma3.it, Polticelli, Fabio⁴ (AUTHOR) fabio.polticelli@uniroma3.it, Palmieri, Luigi^1,3 (AUTHOR) luigi.palmieri@uniba.it, Monné, Magnus^1,5 (AUTHOR) magnus.monne@unibas.it

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13557. 15p.

Subject Terms: *MEMBRANE transport proteins, *MOLECULAR docking, *BIOLOGICAL transport, *BIOCHEMICAL substrates, *ORGANIC acids

Protein Structural Modeling and Transport Thermodynamics Reveal That Plant Cation–Chloride Cotransporters Mediate Potassium–Chloride Symport.

Authors: Henderson, Sam W.¹ (AUTHOR) sam.henderson@adelaide.edu.au, Nourmohammadi, Saeed¹ (AUTHOR), Hrmova, Maria¹ (AUTHOR) maria.hrmova@adelaide.edu.au

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p12955. 20p.

Subject Terms: *MEMBRANE transport proteins, *INTRACELLULAR membranes, *CELL membranes, *PLANT proteins, *XENOPUS laevis

Pharmacokinetic Interaction Between Olaparib and Regorafenib in an Animal Model.

Authors: Szkutnik-Fiedler, Danuta¹ (AUTHOR) akarbownik@ump.edu.pl, Karbownik, Agnieszka¹ (AUTHOR) f.otto@ump.edu.pl, Otto, Filip¹ (AUTHOR) grzesko@ump.edu.pl, Maciejewska, Julia² (AUTHOR) julia.maciejewska1409@gmail.com, Kuźnik, Alicja² (AUTHOR) alicjakuznik00@gmail.com, Grabowski, Tomasz³ (AUTHOR) tomasz.grabowski@gumed.edu.pl, Wolc, Anna^4,5 (AUTHOR) awolc@iastate.edu, Grześkowiak, Edmund¹ (AUTHOR) jstanislawiak@ump.edu.pl, Stanisławiak-Rudowicz, Joanna^1,6 (AUTHOR) eszalek@ump.edu.pl, Szałek, Edyta¹ (AUTHOR)

Source: Pharmaceutics. Dec2024, Vol. 16 Issue 12, p1575. 19p.

Subject Terms: *CYTOCHROME P-450 CYP3A, *MEMBRANE transport proteins, *DRUG interactions, *LABORATORY rats, *BIOCHEMICAL substrates

Lysine 473 Regulates the Progression of SLC7A11, the Cystine/Glutamate Exchanger, through the Secretory Pathway.

Authors: Koppin, Anna¹ (AUTHOR) koppi033@umn.edu, Chase, Leah² (AUTHOR) chase@hope.edu

Source: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10271. 23p.

Subject Terms: *MEMBRANE transport proteins, *C-terminal residues, *ENDOPLASMIC reticulum, *GLUTAMATE transporters, *SITE-specific mutagenesis

Novel Homozygous Variant in the SLC19A2 Gene Causing Thiamine Responsive Megaloblastic Anemia Syndrome: A Disease to Be Considered in Diabetes Clinics.

Authors: Helvaci, Burcak Cavnar¹ burcakcavnar@gmail.com, Saat, Hanife², Hepsen, Sema¹, Helvaci, Özant³, Cakal, Erman³

Source: Endocrinology Research & Practice. Oct2024, Vol. 28 Issue 4, p236-239. 4p.

Subject Terms: *MEMBRANE transport proteins, *GLYCOSYLATED hemoglobin, *GLYCEMIC control, *OPTICAL coherence tomography, *SENSORINEURAL hearing loss, *VITAMIN B1, *CONSANGUINITY, *ORAL drug administration, *GENETIC variation, *ELECTROMYOGRAPHY, *POLYNEUROPATHIES, *MACROCYTIC anemia, *GENETIC mutation, *DIABETES, *GENETIC testing, *LIPOIC acid

Geographic Terms: TURKEY

The Solute Carrier (SLC) Transporter Superfamily as Therapeutic Targets for the Treatment of Head and Neck Squamous Cell Carcinoma.

Authors: Cho, Sang Yeon^1,2 (AUTHOR) nprc26@cnu.ac.kr, Kang, Nam Sook¹ (AUTHOR) nskang@cnu.ac.kr

Source: Cancers. Sep2024, Vol. 16 Issue 18, p3226. 13p.

Subject Terms: *SQUAMOUS cell carcinoma, *MEMBRANE transport proteins, *TISSUES, *EPITHELIAL-mesenchymal transition, *RESEARCH funding, *HEAD & neck cancer, *ANTINEOPLASTIC agents, *TUMOR markers, *CANCER patients, *CELLULAR signal transduction, *GENE expression, *MESSENGER RNA, *METASTASIS, *HUMAN genome, *PROGRESSION-free survival, *PATHOLOGIC neovascularization, *DRUG development, *INDIVIDUALIZED medicine, *OVERALL survival, *HYPOXEMIA, *DISEASE progression, *PHARMACODYNAMICS

Analysis of ATP7A Expression and Ceruloplasmin Levels as Biomarkers in Patients Undergoing Neoadjuvant Chemotherapy for Advanced High-Grade Serous Ovarian Carcinoma.

Authors: Lukanović, David^1,2 (AUTHOR) david.lukanovic@kclj.si, Polajžer, Sara³ (AUTHOR) sara.polajzer@mf.uni-lj.si, Matjašič, Miha⁴ (AUTHOR) miha.matjasic@pef.uni-lj.si, Kobal, Borut^1,2 (AUTHOR) borut.kobal@kclj.si, Černe, Katarina³ (AUTHOR) katarina.cerne@mf.uni-lj.si

Source: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p10195. 18p.

Subject Terms: *BLOOD proteins, *MEMBRANE transport proteins, *NEOADJUVANT chemotherapy, *DRUG resistance, *TUMOR markers, *FALLOPIAN tubes, *OMENTUM

The ABCG2 Transporter Affects Plasma Levels, Tissue Distribution and Milk Secretion of Lumichrome, a Natural Derivative of Riboflavin.

Authors: Millán-García, Alicia¹ (AUTHOR) amilg@unileon.es, Álvarez-Fernández, Laura¹ (AUTHOR), Blanco-Paniagua, Esther¹ (AUTHOR), Álvarez, Ana I.¹ (AUTHOR), Merino, Gracia¹ (AUTHOR) gmerp@unileon.es

Source: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p9884. 12p.

Subject Terms: *LACTATION, *MEMBRANE transport proteins, *PHOTODYNAMIC therapy, *SMALL intestine, *ANTINEOPLASTIC agents, *VITAMIN B2

Insights into Transient Dimerisation of Carnitine/Acylcarnitine Carrier (SLC25A20) from Sarkosyl/PAGE, Cross-Linking Reagents, and Comparative Modelling Analysis.

Authors: Giangregorio, Nicola¹ (AUTHOR) a.tonazzi@ibiom.cnr.it, Tonazzi, Annamaria¹ (AUTHOR) c.indiveri@ibiom.cnr.it, Pierri, Ciro Leonardo² (AUTHOR) n.giangregorio@ibiom.cnr.it, Indiveri, Cesare^1,3 (AUTHOR)

Source: Biomolecules (2218-273X). Sep2024, Vol. 14 Issue 9, p1158. 26p.

Subject Terms: *MEMBRANE transport proteins, *SITE-specific mutagenesis, *STRUCTURAL dynamics, *MITOCHONDRIAL membranes, *CARNITINE

A Village in the Southeastern Region of Iran Harboring the c.716T>A (p.Val239Asp) Mutation in SLC26A4.

Authors: Ashrafi, Farzane Zare¹, Dorgaleleh, Saeed¹, Rezvandeh, Raziye Rezvani¹, Kazemi, Negar¹, Azizi, Nasrin¹, Edizadeh, Masoud^2,3, Azizi, Mohammad Hossein⁴, Kahrizi, Kimia¹, Najmabadi, Hossein¹, Najafipour, Reza¹, Mohseni, Marzieh¹ mohseni_mh@yahoo.com

Source: Archives of Iranian Medicine (AIM). Sep2024, Vol. 27 Issue 9, p522-526. 5p.

Subject Terms: *MEMBRANE transport proteins, *AUDITORY perception testing, *GENEALOGY, *GENETIC counseling, *DECISION making in clinical medicine, *AMINO acids, *HEARING disorders, *GENETIC mutation, *GENETIC techniques, *GENETIC testing, *SEQUENCE analysis

Geographic Terms: IRAN, PAKISTAN

The Human OCTN Sub-Family: Gene and Protein Structure, Expression, and Regulation.

Authors: Galluccio, Michele¹ (AUTHOR) michele.galluccio@unical.it, Tripicchio, Martina¹ (AUTHOR), Pochini, Lorena^1,2 (AUTHOR) michele.galluccio@unical.it

Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8743. 16p.

Subject Terms: *MEMBRANE transport proteins, *GENETIC regulation, *SOMATIC mutation, *GENE expression, *MUTANT proteins

ABCA1 Deletion Does Not Affect Aqueous Humor Outflow Function in Mice.

Authors: Qin, Bo^1,2,3 (AUTHOR), Hu, Chunchun^1,2,3 (AUTHOR), Zhang, Youjia^1,2,3 (AUTHOR), Chen, Yuhong^1,2,3 (AUTHOR) yuhongchen@fudan.edu.cn, Lei, Yuan^1,2,3 (AUTHOR) lilian0167@hotmail.com, Cagini, Carlo (AUTHOR)

Source: Journal of Ophthalmology. 7/17/2024, Vol. 2024, p1-9. 9p.

Subject Terms: *MEMBRANE transport proteins, *BIOLOGICAL models, *RESEARCH funding, *ANTERIOR chamber (Eye), *OPTICAL coherence tomography, *REVERSE transcriptase polymerase chain reaction, *MICE, *MESSENGER RNA, *GENE expression, *MEMBRANE glycoproteins, *ANIMAL experimentation, *SLIT lamp microscopy, *TONOMETRY, *ENUCLEATION of the eye, *WESTERN immunoblotting, *GENETIC mutation, *AQUEOUS humor, *STAINS & staining (Microscopy), *PHENOTYPES

Use of Drug Sensitisers to Improve Therapeutic Index in Cancer.

Authors: Chen, Yu-Shan¹ (AUTHOR) yu-shan.chen@postgrad.manchester.ac.uk, Jin, Enhui¹ (AUTHOR) enhui.jin@postgrad.manchester.ac.uk, Day, Philip J.^1,2 (AUTHOR) philip.j.day@manchester.ac.uk

Source: Pharmaceutics. Jul2024, Vol. 16 Issue 7, p928. 21p.

Subject Terms: *MEMBRANE transport proteins, *DRUG interactions, *DRUG dosage, *ANTINEOPLASTIC agents, *CRITICAL currents

Case report: ocular manifestations of a gain-of-function mutation in CLCN6, a newly diagnosed disease.

Authors: Kimera, Lawrencia¹ (AUTHOR), Nadimpalli, Sameera² (AUTHOR), Kurup, Sudhi^2,3 (AUTHOR), Cole, F. Sessions^4,5 (AUTHOR), Huang, Russell³ (AUTHOR), Sisco, Kathleen⁶ (AUTHOR), Ranaivo, Hantamalala Ranay² (AUTHOR), Shinawi, Marwan⁶ (AUTHOR), Dickson, Patricia⁶ (AUTHOR), Mian, Ali⁷ (AUTHOR), Reynolds, Margaret¹ (AUTHOR) margaret.reynolds@wustl.edu, Undiagnosed Diseases Network (AUTHOR)

Source: Ophthalmic Genetics. Jun2024, Vol. 45 Issue 3, p271-274. 4p.

Subject Terms: *MEMBRANE transport proteins, *CHLORIDE channels, *GAIN-of-function mutations, *ION transport (Biology), *OPTIC nerve

TIM-3 Expression on Dendritic Cells in Colorectal Cancer.

Authors: Sakuma, Mei¹ (AUTHOR) msakuma@fmu.ac.jp, Katagata, Masanori¹ (AUTHOR) okayama@fmu.ac.jp, Okayama, Hirokazu¹ (AUTHOR), Nakajima, Shotaro^1,2 (AUTHOR), Saito, Katsuharu¹ (AUTHOR), Sato, Takahiro¹ (AUTHOR), Fukai, Satoshi¹ (AUTHOR), Tsumuraya, Hideaki¹ (AUTHOR), Onozawa, Hisashi¹ (AUTHOR), Sakamoto, Wataru¹ (AUTHOR), Saito, Motonobu¹ (AUTHOR), Saze, Zenichiro¹ (AUTHOR), Momma, Tomoyuki¹ (AUTHOR), Mimura, Kosaku^1,3 (AUTHOR), Kono, Koji¹ (AUTHOR) kojikono@fmu.ac.jp

Source: Cancers. May2024, Vol. 16 Issue 10, p1888. 12p.

Subject Terms: *MEMBRANE transport proteins, *IN vitro studies, *FLOW cytometry, *CANCER invasiveness, *COLORECTAL cancer, *GENE expression, *IMMUNOHISTOCHEMISTRY, *WESTERN immunoblotting, *DENDRITIC cells, *DISEASE progression