The impact of ECPELLA on haemodynamics and global oxygen delivery: a comprehensive simulation of biventricular failure

Authors: Hiroki Matsushita, Keita Saku, Takuya Nishikawa, Shohei Yokota, Kei Sato, Hidetaka Morita, Yuki Yoshida, Masafumi Fukumitsu, Kazunori Uemura, Toru Kawada, Ken Yamaura

Source: Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-15 (2024)

Subject Terms: Simulation, Cardiogenic shock, VA-ECMO, Impella, ECPELLA, Haemodynamics, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2197-425X

Access URL: https://doaj.org/article/912f96fc2e8b45778aebf069fd5611a9

Computer-controlled closed-loop norepinephrine infusion system for automated control of mean arterial pressure in dogs under isoflurane-induced hypotension: a feasibility study

Authors: Kazumasu Sasaki, Toru Kawada, Hiroki Matsushita, Shohei Yokota, Midori Kakuuchi, Aimi Yokoi, Yuki Yoshida, Hidetaka Morita, Kei Sato, Takuya Nishikawa, Annette P. N. Kutter, Yasuyuki Kataoka, Joe Alexander, Keita Saku, Tatsuya Ishikawa, Kazunori Uemura

Source: Frontiers in Veterinary Science, Vol 11 (2024)

Subject Terms: arterial pressure control, automated control, closed-loop drug infusion system, dog, isoflurane-induced hypotension, norepinephrine, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fvets.2024.1374356/full; https://doaj.org/toc/2297-1769

Access URL: https://doaj.org/article/37db7acad19043b580ca2e3966debd9e

Acute effects of empagliflozin on open-loop baroreflex function and urinary glucose excretion in rats with chronic myocardial infarction

Authors: Toru Kawada, Meihua Li, Akitsugu Nishiura, Yuki Yoshida, Shohei Yokota, Hiroki Matsushita, Masafumi Fukumitsu, Kazunori Uemura, Joe Alexander, Keita Saku

Source: Journal of Physiological Sciences, Vol 73, Iss 1, Pp 1-12 (2023)

Subject Terms: Sodium–glucose cotransporter 2, Sympathetic nerve activity, Arterial pressure, Urine flow, Equilibrium diagram, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/1880-6562

Access URL: https://doaj.org/article/e40a9c4bd9954cdfa2d9900b9322166b

Acute effects of empagliflozin on open-loop baroreflex function and urine glucose excretion in Goto-Kakizaki diabetic rats

Authors: Toru Kawada, Hiromi Yamamoto, Aimi Yokoi, Akitsugu Nishiura, Midori Kakuuchi, Shohei Yokota, Hiroki Matsushita, Joe Alexander, Keita Saku

Source: Journal of Physiological Sciences, Vol 73, Iss 1, Pp 1-12 (2023)

Subject Terms: Sodium–glucose cotransporter 2, Sympathetic nerve activity, Arterial pressure, Urine flow, Equilibrium diagram, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/1880-6562

Access URL: https://doaj.org/article/a0a4113fcfb24f429872f1824ed0f85e

Linear and nonlinear identification of the carotid sinus baroreflex in the very low‐frequency range

Authors: Toru Kawada, Tadayoshi Miyamoto, Ramakrishna Mukkamala, Keita Saku

Source: Physiological Reports, Vol 10, Iss 14, Pp n/a-n/a (2022)

Subject Terms: arterial baroreflex, Gaussian white noise, transfer function, Uryson model, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/2051-817X

Access URL: https://doaj.org/article/4e17153480764785b89de65c0052dc1d

Ivabradine increases the high frequency gain ratio in the vagal heart rate transfer function via an interaction with muscarinic potassium channels

Authors: Toru Kawada, Hiromi Yamamoto, Tadayoshi Miyamoto, Yohsuke Hayama, Meihua Li, Can Zheng, Kazunori Uemura, Masaru Sugimachi, Keita Saku

Source: Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)

Subject Terms: ivabradine, transfer function, vagal nerve stimulation, white noise, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/2051-817X

Access URL: https://doaj.org/article/bf636843e8f3451297e267606343cc94

Closed-Loop Identification of Baroreflex Properties in the Frequency Domain

Authors: Toru Kawada, Keita Saku, Tadayoshi Miyamoto

Source: Frontiers in Neuroscience, Vol 15 (2021)

Subject Terms: baroreflex, white noise, sympathetic nerve activity, arterial pressure, transfer function, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2021.694512/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/0223f0611beb48febf0ff7cd77725404

Computer-controlled closed-loop drug infusion system for automated hemodynamic resuscitation in endotoxin-induced shock

Authors: Kazunori Uemura, Toru Kawada, Can Zheng, Meihua Li, Masaru Sugimachi

Source: BMC Anesthesiology, Vol 17, Iss 1, Pp 1-13 (2017)

Subject Terms: Septic shock, Hemodynamics, Resuscitation, Computer, Closed-loop control, Anesthesiology, RD78.3-87.3

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12871-017-0437-9; https://doaj.org/toc/1471-2253

Access URL: https://doaj.org/article/47967d2127a544d4b270140195867699

Acute Effects of Vagotomy on Baroreflex Equilibrium Diagram in Rats with Chronic Heart Failure

Authors: Toru Kawada, Meihua Li, Can Zheng, Masaru Sugimachi

Source: Clinical Medicine Insights: Cardiology, Vol 2016, Iss 10, Pp 139-147 (2016)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.la-press.com/acute-effects-of-vagotomy-on-baroreflex-equilibrium-diagram-in-rats-wi-article-a5868; https://doaj.org/toc/1179-5468

Access URL: https://doaj.org/article/6dbc89d519dc414e82f1a6c567eeac5b

Periodic Breathing in Heart Failure Explained by Dynamic and Static Properties of Respiratory Control

Authors: Tadayoshi Miyamoto, Hidehiro Nakahara, Shinya Ueda, Kou Manabe, Eriko Kawai, Masashi Inagaki, Toru Kawada, Masaru Sugimachi

Source: Clinical Medicine Insights: Cardiology, Vol 2015, Iss Suppl. 1, Pp 133-142 (2015)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.la-press.com/periodic-breathing-in-heart-failure-explained-by-dynamic-and-static-pr-article-a5170; https://doaj.org/toc/1179-5468

Access URL: https://doaj.org/article/0ac0bf783c2a4838983c771f53ad6a0d

Impact of lipopolysaccharide-induced acute inflammation on baroreflex-controlled sympathetic arterial pressure regulation.

Authors: Takeshi Tohyama, Keita Saku, Toru Kawada, Takuya Kishi, Keimei Yoshida, Takuya Nishikawa, Hiroshi Mannoji, Kazuhiro Kamada, Kenji Sunagawa, Hiroyuki Tsutsui

Source: PLoS ONE, Vol 13, Iss 1, p e0190830 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5766102?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/bf7569b4fc2743d0bd7302c3b429978b

Calibration of Baroreflex Equilibrium Diagram Based on Exogenous Pressor Agents in Chronic Heart Failure Rats

Authors: Toru Kawada, Meihua Li, Yusuke Sata, Can Zheng, Michael J. Turner, Shuji Shimizu, Masaru Sugimachi

Source: Clinical Medicine Insights: Cardiology, Vol 2015, Iss Suppl. 1, Pp 1-9 (2015)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.la-press.com/calibration-of-baroreflex-equilibrium-diagram-based-on-exogenous-press-article-a4648; https://doaj.org/toc/1179-5468

Access URL: https://doaj.org/article/4fdf3dd83e8a4b568ffa1d1f7dc83021

Short-term dynamic characteristics of diuresis during exogenous pressure perturbations with and without arterial baroreflex control.

Authors: Toru Kawada¹ torukawa@ncvc.go.jp, Hiroki Matsushita¹, Shohei Yokota¹, Yuki Yoshida¹, Masafumi Fukumitsu¹, Alexander Jr., Joe², Saku, Keita^1,3

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Mar2024, Vol. 326 Issue 3, pR230-R241. 12p.

Subject Terms: *BAROREFLEXES, *DIURESIS, *EXPONENTIAL sums, *LABORATORY rats, *WHITE noise, *STRETCH reflex

Input-size dependence of the baroreflex neural arc transfer characteristics during Gaussian white noise inputs.

Authors: Toru Kawada¹ torukawa@ncvc.go.jp, Tadayoshi Miyamoto², Masafumi Fukumitsu¹, Keita Saku^1,3

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Feb2024, Vol. 326 Issue 2, pR121-R133. 13p.

Subject Terms: *RANDOM noise theory, *BAROREFLEXES, *LABORATORY rats, *BARORECEPTORS, *STANDARD deviations, *WHITE noise, *ELECTRIC arc

Dynamic accentuated antagonism of heart rate control during different levels of vagal nerve stimulation intensity in rats.

Authors: Toru Kawada¹ torukawa@ncvc.go.jp, Aimi Yokoi¹, Akitsugu Nishiura¹, Midori Kakuuchi¹, Shohei Yokota¹, Hiroki Matsushita¹, Meihua Li¹, Kazunori Uemura¹, Keita Saku¹

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Feb2023, Vol. 324 Issue 2, pR260-R270. 11p.

Subject Terms: *HYPERPOLARIZATION (Cytology), *VAGUS nerve stimulation, *HEART beat, *NEURAL stimulation, *LABORATORY rats, *TRANSFER functions

Impact of neurally mediated antidiuretic effect relative to pressure diuresis during acute changes in sympathetic nerve activity.

Authors: Toru Kawada¹ torukawa@ncvc.go.jp, Aimi Yokoi¹, Akitsugu Nishiura¹, Midori Kakuuchi¹, Meihua Li¹, Kazunori Uemura¹, Satoru Suehara², Satoshi Sawada², Keita Saku¹

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Jan2023, Vol. 324 Issue 1, pR82-R89. 8p.

Subject Terms: *DIURESIS, *LABORATORY rats, *NERVES, *EXCRETION, *BODY weight

Ivabradine augments high-frequency dynamic gain of the heart rate response to low- and moderate-intensity vagal nerve stimulation under β-blockade.

Authors: Toru Kawada¹ torukawa@ncvc.go.jp, Hiromi Yamamoto^2,3, Kazunori Uemura¹, Yohsuke Hayama¹, Takuya Nishikawa¹, Can Zheng¹, Meihua Li¹, Tadayoshi Miyamoto⁴, Masaru Sugimachi¹

Source: American Journal of Physiology: Heart & Circulatory Physiology. Jun2021, Vol. 320 Issue 6, pH2201-H2210. 10p.

Subject Terms: *NEURAL stimulation, *HEART beat, *VAGUS nerve, *CYCLIC adenylic acid, *IVABRADINE, *LABORATORY rats

Open-loop analysis on sympathetically mediated arterial pressure and urine output responses in spontaneously hypertensive rats: effect of renal denervation.

Authors: Toru Kawada, Takuya Nishikawa, Satoru Suehara, Satoshi Sawada, Tetsuo Tanaka, Minako Uenohara, Hiromi Yamamoto, Masaru Sugimachi

Source: Journal of Physiological Sciences; Jan2021, Vol. 71 Issue 1, p1-9, 9p, 3 Charts, 2 Graphs

Contribution of afferent pathway to vagal nerve stimulation-induced myocardial interstitial acetylcholine release in rats.

Authors: Toru Kawada¹ torukawa@ncvc.go.jp, Takashi Sonobe², Takuya Nishikawa¹, Yohsuke Hayama¹, Meihua Li¹, Can Zheng¹, Kazunori Uemura¹, Tsuyoshi Akiyama², Pearson, James T.^2,3, Masaru Sugimachi¹

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Nov2020, Vol. 319 Issue 5, pR517-R525. 9p.

Subject Terms: *AFFERENT pathways, *EFFERENT pathways, *NEURAL stimulation, *MYOCARDIUM, *NERVES, *RATS

Geographic Terms: KYOTO (Japan)

Contrasting open-loop dynamic characteristics of sympathetic and vagal systems during baroreflex-mediated heart rate control in rats.

Authors: Toru Kawada¹ torukawa@ncvc.go.jp, Hiromi Yamamoto², Yohsuke Hayama¹, Takuya Nishikawa¹, Kunihiko Tanaka³, Masaru Sugimachi¹

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Dec2019, Vol. 317 Issue 6, pR879-R890. 12p.

Subject Terms: *HEART beat, *PARASYMPATHETIC nervous system, *RAT control, *RANDOM noise theory, *SYMPATHETIC nervous system