Maternal and Fetal Expression of ATP-Binding Cassette and Solute Carrier Transporters Involved in the Brain Disposition of Drugs

Authors: Torres-Vergara, Pablo, Rivera, Robin, Escudero, Carlos, Penny, Jeffrey

Source: Advances in experimental medicine and biology. 1428:149-178

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633334820&indx=1&recIds=ETOCRN633334820

Brain Vascular Dysfunction in Mothers and Their Children Exposed to Preeclampsia

Authors: Escudero, Carlos, Kupka, Ellen, Ibañez, Belen, Sandoval, Hermes, Troncoso, Felipe, Wikström, Anna-Karin, López-Espíndola, Daniela, Acurio, Jesenia, Torres-Vergara, Pablo, Bergman, Lina

Source: Hypertension. 80(2):242-256

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178276522.0x000001&indx=1&recIds=ETOCvdc_100178276522.0x000001

Regulation of the ATP‐binding cassette transporters ABCB1, ABCG2 and ABCC5 by nuclear receptors in porcine blood–brain barrier endothelial cells.

Authors: Ho, Yu Siong¹ (AUTHOR), Torres‐Vergara, Pablo² (AUTHOR) pabltorr@udec.cl, Penny, Jeffrey¹ (AUTHOR) jeffrey.penny@manchester.ac.uk

Source: British Journal of Pharmacology. Dec2023, Vol. 180 Issue 23, p3092-3109. 18p.

Subject Terms: *ATP-binding cassette transporters, *BLOOD-brain barrier, *P-glycoprotein, *ENDOTHELIAL cells, *FLUORESCENT probes

Disruption of the Blood-Brain Barrier by Extracellular Vesicles From Preeclampsia Plasma and Hypoxic Placentae: Attenuation by Magnesium Sulfate

Authors: León, José, Acurio, Jesenia, Bergman, Lina, López, Juán, Karin Wikström, Anna, Torres-Vergara, Pablo, Troncoso, Felipe, Castro, Fidel Ovidio, Vatish, Manu, Escudero, Carlos

Source: Hypertension. 78(5):1423-1433

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176825031.0x000001&indx=1&recIds=ETOCvdc_100176825031.0x000001

The constitutive androstane receptor and pregnane X receptor in the brain

Authors: Torres‐Vergara, Pablo, Ho, Yu Siong, Espinoza, Francisca, Nualart, Francisco, Escudero, Carlos, Penny, Jeffrey

Source: British journal of pharmacology. 177(12):2666-2682

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107413617.0x000001&indx=1&recIds=ETOCvdc_100107413617.0x000001

Deletion of the adenosine A2A receptor increases the survival rate in a mice model of polymicrobial sepsis

Authors: Meriño, Miguel, Martín, Sebastián San, Sandaña, Pedro, Herlitz, Kurt, Aguayo, Claudio, Godoy, Alejandro, Torres-Vergara, Pablo, Gonzalez, Marcelo, Troncoso, Felipe, Acurio, Jesenia, Escudero, Carlos

Source: Purinergic signalling. 16(3):427-437

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171785978.0x000001&indx=1&recIds=ETOCvdc_100171785978.0x000001

Basal Sodium-Dependent Vitamin C Transporter 2 polarization in choroid plexus explant cells in normal or scorbutic conditions

Authors: Ulloa, Viviana, Saldivia, Natalia, Ferrada, Luciano, Salazar, Katterine, Martínez, Fernando, Silva-Alvarez, Carmen, Magdalena, Rocio, Oviedo, María, Montecinos, Hernán, Torres-Vergara, Pablo, Cifuentes, Manuel, Nualart, Francisco

Source: Scientific reports. 9(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190843279.0x000001&indx=1&recIds=ETOCvdc_100190843279.0x000001

Dysregulation of vascular endothelial growth factor receptor 2 phosphorylation is associated with disruption of the blood-brain barrier and brain endothelial cell apoptosis induced by plasma from women with preeclampsia

Authors: Torres-Vergara, Pablo, Troncoso, Felipe, Acurio, Jesenia, Kupka, Ellen, Bergman, Lina, Wikström, Anna-Karin, Escudero, Carlos

Source: Biochimica et biophysica acta. 1868(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196357116.0x000001&indx=1&recIds=ETOCvdc_100196357116.0x000001

Development, characterization and in vitro evaluation of biodegradable rhein-loaded microparticles for treatment of osteoarthritis

Authors: Gómez-Gaete, Carolina, Retamal, Macarena, Chávez, Catalina, Bustos, Paulina, Godoy, Ricardo, Torres-Vergara, Pablo

Source: In European Journal of Pharmaceutical Sciences 1 January 2017 96:390-397

Capreomycin oleate microparticles for intramuscular administration: Preparation, in vitro release and preliminary in vivo evaluation

Authors: Cambronero-Rojas, Adrián, Torres-Vergara, Pablo, Godoy, Ricardo, von Plessing, Carlos, Sepúlveda, Jacqueline, Gómez-Gaete, Carolina

Source: In Journal of Controlled Release 10 July 2015 209:229-237

Investigating Maternal Brain Alterations in Preeclampsia: the Need for a Multidisciplinary Effort

Authors: Bergman, Lina, Torres-Vergara, Pablo, Penny, Jeffrey, Wikström, Johan, Nelander, Maria, Leon, Jose, Tolcher, Mary, Roberts, James M., Wikström, Anna-Karin, Escudero, Carlos

Source: Current hypertension reports. 21(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128372260.0x000001&indx=1&recIds=ETOCvdc_100128372260.0x000001

DEVELOPMENT AND OPTIMIZATION OF TERIFLUNOMIDE-LOADED CHONDROITIN SULPHATE-COATED NANOSTRUCTURED LIPID CARRIERS (NLCS) THROUGH BOX BEHNKEN DESIGN.

Authors: CAMPOS, CRISTÓBAL, TORRES-VERGARA, PABLO, GODOY, RICARDO, RIQUELME, CRISTINA, ARELLANO-VILLASEÑOR, NOEMI, CHAVEZ-SANTOSCOY, ROCIO ALEJANDRA, HERBAS-GOITÍA, ISABEL, GOMEZ-GAETE, CAROLINA

Source: Journal of the Chilean Chemical Society; 2023, Vol. 68 Issue 2, p5832-5838, 7p

Subject Terms: CHONDROITIN sulfates, RHEUMATOID arthritis, AUTOIMMUNE diseases, ZETA potential, JOINT pain, LEFLUNOMIDE, NANOSTRUCTURED materials, DYNAMICS, JOINT diseases

Brain Vascular Dysfunction in Mothers and Their Children Exposed to Preeclampsia.

Authors: Escudero, Carlos, Kupka, Ellen, Ibañez, Belen, Sandoval, Hermes, Troncoso, Felipe, Wikström, Anna-Karin, López-Espíndola, Daniela, Acurio, Jesenia, Torres-Vergara, Pablo, Bergman, Lina

Source: Hypertension (0194911X); Feb223, Vol. 80 Issue 2, p242-256, 15p

How Soluble Fms-Like Tyrosine Kinase 1 Could Contribute to Blood-Brain Barrier Dysfunction in Preeclampsia?

Authors: Torres-Vergara, Pablo, Rivera, Robin, Escudero, Carlos

Source: Frontiers in Physiology; 2/8/2022, Vol. 13, p1-9, 9p

Subject Terms: PLACENTAL growth factor, HELLP syndrome, ENDOTHELIUM diseases, VASCULAR endothelial growth factor receptors, PROTEIN-tyrosine kinases, BLOOD-brain barrier, PREECLAMPSIA

Preeclampsia and Increased Permeability Over the Blood–Brain Barrier: A Role of Vascular Endothelial Growth Receptor 2.

Authors: Bergman, Lina, Acurio, Jesenia, Leon, Jose, Gatu, Emily, Friis, Therese, Nelander, Maria, Wikström, Johan, Larsson, Anders, Lara, Evelyn, Aguayo, Claudio, Torres-Vergara, Pablo, Wikström, Anna-Karin, Escudero, Carlos

Source: American Journal of Hypertension; Jan2021, Vol. 34 Issue 1, p73-81, 9p

Subject Terms: VASCULAR endothelial growth factor receptors, BLOOD-brain barrier, PREECLAMPSIA, PLACENTAL growth factor, MESSENGER RNA

Deletion of the adenosine A2A receptor increases the survival rate in a mice model of polymicrobial sepsis.

Authors: Meriño, Miguel, Martín, Sebastián San, Sandaña, Pedro, Herlitz, Kurt, Aguayo, Claudio, Godoy, Alejandro, Torres-Vergara, Pablo, Gonzalez, Marcelo, Troncoso, Felipe, Acurio, Jesenia, Escudero, Carlos

Source: Purinergic Signalling; Sep2020, Vol. 16 Issue 3, p427-437, 11p

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Increased cerebral biomarkers in plasma and decreased intracerebral magnesium levels are correlated to an impaired blood brain barrier in vitro in preeclampsia

Authors: Friis, Therese, Wikström, Anna-Karin, Acurio, Jesenia, Leon, Jose, Zetterberg, Henrik, Blennow, Kaj, Nelander, Maria, Åkerud, Helena, Kaihola, Helena, Cluver, Catherine, Wikström, Johan, Torres-Vergara, Pablo, Bergman, Lina, Escudero, Carlos

Source: In Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health October 2019 17 Supplement 1:S14-S15

Are the Cognitive Alterations Present in Children Born From Preeclamptic Pregnancies the Result of Impaired Angiogenesis? Focus on the Potential Role of the VEGF Family.

Authors: Lara, Evelyn, Acurio, Jesenia, Leon, José, Penny, Jeffrey, Torres-Vergara, Pablo, Escudero, Carlos

Source: Frontiers in Physiology; 11/14/2018, pN.PAG-N.PAG, 10p