IL-17 triggers PD-L1 gene transcription in NSCLC cells via TRIM31-dependent MEF2C K63-linked polyubiquitination

Authors: Shuai Ying, Ningxia Wu, Yuting Ruan, Wen Ge, Pei Ma, Tongpeng Xu, Yongqian Shu, Yingwei Wang, Wen Qiu, Chenhui Zhao

Source: BMC Cancer, Vol 25, Iss 1, Pp 1-17 (2025)

Subject Terms: NSCLC, IL-17, PD-L1, MEF2C, TRIM31, K63-linked polyubiquitination, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/0f8773ac20eb46289507e7cd63211547

Efficacy and safety of novel multiple-chain DAP-CAR-T cells targeting mesothelin in ovarian cancer and mesothelioma: a single-arm, open-label and first-in-human study

Authors: Tongpeng Xu, Tian Tian, Chen Wang, Xiaofeng Chen, Xiangrong Zuo, Hanyu Zhou, Jianan Bai, Chenhui Zhao, Sujie Fu, Chongqi Sun, Ting Wang, Ling Zhu, Jingzhi Zhang, Enxiu Wang, Ming Sun, Yongqian Shu

Source: Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)

Subject Terms: MSLN, CAR-T cells, Ovarian cancer, Mesothelioma, Safety, Efficacy, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/6b50711b262f4cfdbe647fef7b8bbc12

First-line camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and chemotherapy for advanced gastric cancer (SPACE): a phase 1 study

Authors: Xiaofeng Chen, Hao Xu, Xiaobing Chen, Tongpeng Xu, Yitong Tian, Deqiang Wang, Fen Guo, Kangxin Wang, Guangfu Jin, Xiao Li, Rong Wang, Fengyuan Li, Yongbin Ding, Jie Tang, Yueyu Fang, Jing Zhao, Liang Liu, Ling Ma, Lijuan Meng, Zhiguo Hou, Rongrong Zheng, Yang Liu, Ni Guan, Bei Zhang, Shuang Tong, Shiqing Chen, Xing Li, Yongqian Shu

Source: Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-8 (2024)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/7a70679d73974d70be756d1e0e474fad

Novel two-chain structure utilizing KIRS2/DAP12 domain improves the safety and efficacy of CAR-T cells in adults with r/r B-ALL

Authors: Ming Sun, Peipei Xu, Enxiu Wang, Min Zhou, Tongpeng Xu, Jing Wang, Qian Wang, Bo Wang, Kaihua Lu, Chen Wang, Bing Chen

Source: Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 96-106 (2021)

Subject Terms: r/r B-ALL, CAR-T cells, KIRS2/DAP12 signaling domain, 4-1BB, clinical trial, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S237277052100125X; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/ed1b4f1d6e464db28f63138acac27495

LINC00675 Suppresses Cell Proliferation and Migration via Downregulating the H3K4me2 Level at the SPRY4 Promoter in Gastric Cancer

Authors: Yutian Pan, Yuan Fang, Mengyan Xie, Yu Liu, Tao Yu, Xi Wu, Tongpeng Xu, Pei Ma, Yongqian Shu

Source: Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 766-778 (2020)

Subject Terms: gastric cancer, LINC00675, LSD1, H3K4me2, SPRY4, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253120303097; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/5f3b8dfac889414281516c2b685a62cc

KLF5-Modulated lncRNA NEAT1 Contributes to Tumorigenesis by Acting as a Scaffold for BRG1 to Silence GADD45A in Gastric Cancer

Authors: Pei Ma, Yutian Pan, Fan Yang, Yuan Fang, Weitao Liu, Chenhui Zhao, Tao Yu, Mengyan Xie, Xingming Jing, Xi Wu, Chongqi Sun, Wei Li, Tongpeng Xu, Yongqian Shu

Source: Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 382-395 (2020)

Subject Terms: NEAT1, tumorigenesis, prognosis, gastric cancer, epigenetics, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253120302742; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/88700aba02ce4dffae02991d168a3038

Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p/HUR/VEGF axis and suppressing HSP90 degradation

Authors: Mengyan Xie, Tao Yu, Xinming Jing, Ling Ma, Yu Fan, Fengming Yang, Pei Ma, Huning Jiang, Xi Wu, Yongqian Shu, Tongpeng Xu

Source: Molecular Cancer, Vol 19, Iss 1, Pp 1-22 (2020)

Subject Terms: CircSHKBP1, Gastric cancer, MiR-582-3p, HUR, VEGF, HSP90, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12943-020-01208-3; https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/df8a210b34314d0cb034490f3cc496af

TEAD4 modulated LncRNA MNX1-AS1 contributes to gastric cancer progression partly through suppressing BTG2 and activating BCL2

Authors: You Shuai, Zhonghua Ma, Weitao Liu, Tao Yu, Changsheng Yan, Hua Jiang, Shengwang Tian, Tongpeng Xu, Yongqian Shu

Source: Molecular Cancer, Vol 19, Iss 1, Pp 1-20 (2020)

Subject Terms: LncRNA, Gastric cancer, TEAD4, MNX1-AS1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/dee5c0635262487d8634079844b0c040

CircRNAs in cancer metabolism: a review

Authors: Tao Yu, Yanfen Wang, Yu Fan, Na Fang, Tongshan Wang, Tongpeng Xu, Yongqian Shu

Source: Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-10 (2019)

Subject Terms: Cancer metabolism, CircRNAs, Warburg effect, Lipid metabolism, Glutamine, ROS, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-019-0776-8; https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/a8a94aef9e8d402fbf07ab6c1955359b

Role of CXCR4 as a Prognostic Biomarker Associated With the Tumor Immune Microenvironment in Gastric Cancer

Authors: Yuyang Gu, Wenyue Gu, Rongrong Xie, Zhi Chen, Tongpeng Xu, Zhenghua Fei

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: CXCR4, tumor microenvironment, gastric cancer, ESTIMATE algorithm, CIBERSORT algorithm, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.654504/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/7ef04881e81b413e8d4ddd1587733e13

Establishment of a Novel Risk Score System of Immune Genes Associated With Prognosis in Esophageal Carcinoma

Authors: Zhenghua Fei, Rongrong Xie, Zhi Chen, Junhui Xie, Yuyang Gu, Yue Zhou, Tongpeng Xu

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: esophageal carcinoma, histological subtype, immune gene, prognostic model index, risk score, bioinformatics, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.625271/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a4b0940e18d34540be1af7b604e208c8

Potential Regulatory Roles of MicroRNAs and Long Noncoding RNAs in Anticancer Therapies

Authors: Mengyan Xie, Ling Ma, Tongpeng Xu, Yutian Pan, Qiang Wang, Yutian Wei, Yongqian Shu

Source: Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 233-243 (2018)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253118302348; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/39f03daace8649d298930d48a369285c

miR-449a Suppresses Tamoxifen Resistance in Human Breast Cancer Cells by Targeting ADAM22

Authors: Jun Li, Mingjie Lu, Jiao Jin, Xiyi Lu, Tongpeng Xu, Shidai Jin

Source: Cellular Physiology and Biochemistry, Vol 50, Iss 1, Pp 136-149 (2018)

Subject Terms: Tamoxifen resistance, Estrogen receptor, Breast cancer, miR-449a, ADAM22, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/493964; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

Access URL: https://doaj.org/article/1175edee9f3b4398ae4eed82ea2969bf

Extracellular vesicles-mediated noncoding RNAs transfer in cancer

Authors: Pei Ma, Yutian Pan, Wei Li, Chongqi Sun, Jie Liu, Tongpeng Xu, Yongqian Shu

Source: Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-11 (2017)

Subject Terms: Extracellular vesicles, Noncoding RNAs, Cancer, Mechanism, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-017-0426-y; https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/818f3ad99f964f14ab1d27eb66410a79

Alteration in Mir-21/PTEN expression modulates gefitinib resistance in non-small cell lung cancer.

Authors: Hua Shen, Fang Zhu, Jinyuan Liu, Tongpeng Xu, Dong Pei, Rong Wang, Yingying Qian, Qi Li, Lin Wang, Zhumei Shi, Jitai Zheng, Qiudan Chen, Binghua Jiang, Yongqian Shu

Source: PLoS ONE, Vol 9, Iss 7, p e103305 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4110008?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e33e3ae9177e4b7b9b1d7195a00d255b

IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation.

Authors: WEN GE, YA LI, YUTING RUAN, NINGXIA WU, PEI MA, TONGPENG XU, YONGQIAN SHU, YINGWEI WANG, WEN QIU, CHENHUI ZHAO

Source: Oncology Research; 2024, Vol. 32 Issue 4, p625-641, 17p

Subject Terms: CELL migration, INTERLEUKIN-17, CELL migration inhibition, METASTATIC breast cancer, GENE expression, NON-small-cell lung carcinoma, TRANSCRIPTION factors, ACETYLATION

Pemetrexed-carboplatin with intercalated icotinib in the treatment of patient with advanced EGFR wild-type lung adenocarcinoma: A case report.

Authors: Tongpeng Xu, Hao Wu, Shidai Jin, Huang Min, Zhihong Zhang, Yongqian Shu, Wei Wen, Renhua Guo, Xu, Tongpeng, Wu, Hao, Jin, Shidai, Min, Huang, Zhang, Zhihong, Shu, Yongqian, Wen, Wei, Guo, Renhua

Source: Medicine; 8/18/2017, Vol. 96 Issue 33, p1-5, 5p

Plumbagin enhances TRAIL-induced apoptosis of human leukemic Kasumi‑1 cells through upregulation of TRAIL death receptor expression, activation of caspase-8 and inhibition of cFLIP.

Authors: XIAOYANG KONG, JING LUO, TONGPENG XU, YUNJIAO ZHOU, ZENGKAI PAN, YINGHUA XIE, LIMIN ZHAO, YINGTING LU, XIYAO HAN, ZHIXIONG LI, LIGEN LIU

Source: Oncology Reports; Jun2017, Vol. 37 Issue 6, p3423-3432, 10p, 5 Graphs

H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma.

Authors: Erbao Zhang, Liang Han, Dandan Yin, Xuezhi He, Linzhi Hong, Xinxin Si, Mantang Qiu, Tongpeng Xu, Wei De, Lin Xu, Yongqian Shu, Jinfei Chen

Source: Nucleic Acids Research; 4/7/2017, Vol. 45 Issue 6, p3086-3101, 16p

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