Pharmacokinetic interaction of calcitriol with 20(S)-protopanaxadiol in mice: Determined by LC/MS analysis

Authors: Ben-Eltriki, Mohamed, Hassona, Mohamed, Meckling, Gray, Adomat, Hans, Deb, Subrata, Tomlinson Guns, Emma S.

Source: In European Journal of Pharmaceutical Sciences 15 March 2019 130:173-180

Diindolylmethane and its halogenated derivatives induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK)

Authors: Draz, Hossam, Goldberg, Alexander A., Titorenko, Vladimir I., Tomlinson Guns, Emma S., Safe, Stephen H., Sanderson, J. Thomas

Source: In Cellular Signalling December 2017 40:172-182

Autophagy inhibition improves the chemotherapeutic efficacy of cruciferous vegetable-derived diindolymethane in a murine prostate cancer xenograft model

Authors: Draz, Hossam, Goldberg, Alexander A., Tomlinson Guns, Emma S., Fazli, Ladan, Safe, Stephen, Sanderson, J. Thomas

Source: Investigational new drugs. 36(4):718-725

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127315876.0x000001&indx=1&recIds=ETOCvdc_100127315876.0x000001

Calcitriol and 20(S)-protopanaxadiol synergistically inhibit growth and induce apoptosis in human prostate cancer cells

Authors: Ben-Eltriki, Mohamed, Deb, Subrata, Adomat, Hans, Tomlinson Guns, Emma S.

Source: In Journal of Steroid Biochemistry and Molecular Biology April 2016 158:207-219

A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice

Authors: Fokidis, H. Bobby, Yieng Chin, Mei, Ho, Victor W., Adomat, Hans H., Soma, Kiran K., Fazli, Ladan, Nip, Ka Mun, Cox, Michael, Krystal, Gerald, Zoubeidi, Amina, Tomlinson Guns, Emma S.

Source: In Journal of Steroid Biochemistry and Molecular Biology June 2015 150:35-45

Selectively Targeting the DNA-binding Domain of the Androgen Receptor as a Prospective Therapy for Prostate Cancer

Authors: Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hessein, Mohamed, Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem, Rennie, Paul S.

Source: In Journal of Biological Chemistry 19 September 2014 289(38):26417-26429

Pharmacokinetics and pharmacodynamics of Rh2 and aPPD ginsenosides in prostate cancer: a drug interaction perspective.

Authors: Ben-Eltriki, Mohamed, Shankar, Gehana, Tomlinson Guns, Emma S., Deb, Subrata

Source: Cancer Chemotherapy & Pharmacology; Dec2023, Vol. 92 Issue 6, p419-437, 19p

Subject Terms: DRUG interactions, PROSTATE cancer, GINSENOSIDES, PHARMACOKINETICS, PHARMACODYNAMICS, ABIRATERONE acetate, CYTOCHROME c

Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells.

Authors: Yenki, Parvin, Bhasin, Satyam, Liang Liu, Nabavi, Noushin, Chi Wing Cheng, Tam, Kevin J., Peacock, James W., Adomat, Hans H., Tombe, Tabitha, Fazli, Ladan, Ivanova, Larissa, Dusek, Christopher, Khosravi, Shahram, Tomlinson Guns, Emma S., Wang, Yuzhuo, Buttyan, Ralph, Gleave, Martin E., Ong, Christopher J.

Source: Endocrine-Related Cancer; Dec2023, Vol. 30 Issue 12, p20-33, 14p

Subject Terms: STEROL regulatory element-binding proteins, SEMAPHORINS, CASTRATION-resistant prostate cancer, ANDROGEN receptors, PROSTATE cancer

Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins Derived from a Panel of Prostate Cell Lines with Distinct AR Phenotypes

Alternate Title: Exosomes: Novel Biomarkers or Therapeutic Targets? (English)

Authors: Hosseini-Beheshti, Elham ^{‡, ¶}, Pham, Steven ^¶, Adomat, Hans ^¶, Li, Na ^¶, Tomlinson Guns, Emma S. ^{§, ¶, ‖}

Source: In Molecular & Cellular Proteomics October 2012 11(10):863-885

Effect of Dexamethasone on Abiraterone Pharmacokinetics in Mice: Determined by LC/MS Analysis.

Authors: Deb, Subrata, Ben-Eltriki, Mohamed, Adomat, Hans, Chin, Mei Y., Tomlinson Guns, Emma S.

Source: Medicines; Mar2023, Vol. 10 Issue 3, p21, 8p

Subject Terms: ABIRATERONE acetate, LIQUID chromatography-mass spectrometry, DEXAMETHASONE, CASTRATION-resistant prostate cancer, PROSTATE cancer patients, CYTOCHROME P-450

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

Authors: Armstrong, Heather K., Gillis, Joanna L., Johnson, Ian R. D., Nassar, Zeyad D., Moldovan, Max, Levrier, Claire, Sadowski, Martin C., Chin, Mei Yieng, Tomlinson Guns, Emma S., Tarulli, Gerard, Lynn, David J., Brooks, Douglas A., Selth, Luke A., Centenera, Margaret M., Butler, Lisa M.

Source: Scientific reports. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131377582.0x000001&indx=1&recIds=ETOCvdc_100131377582.0x000001

Diet and Dietary Supplement Intervention Trials for the Prevention of Prostate Cancer Recurrence: A Review of the Randomized Controlled Trial Evidence

Authors: Van Patten, Cheri L., de Boer, Johan G., Tomlinson Guns, Emma S.

Source: In The Journal of Urology 2008 180(6):2314-2322

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Authors: Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hassona, Mohamed D., Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem, Rennie, Paul S.

Source: In Journal of Biological Chemistry 10 March 2017 292(10):4359-4359

Epidermal Growth Factor Receptor in Prostate Cancer Derived Exosomes.

Authors: Kharmate, Geetanjali, Hosseini-Beheshti, Elham, Caradec, Josselin, Chin, Mei Yieng, Tomlinson Guns, Emma S.

Source: PLoS ONE; 5/6/2016, Vol. 11 Issue 5, p1-14, 14p

Subject Terms: EPIDERMAL growth factor receptors, PROSTATE tumors, EXOSOMES, BIOMARKERS, CELL lines, MICRORNA

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Authors: Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hassona, Mohamed D., Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem, Rennie, Paul S.

Source: In Journal of Biological Chemistry 23 October 2015 290(43):25850-25850

Tenth International Conference of the Society for Integrative Oncology Translational Science in Integrative Oncology: From Bedside to Bench to Best Practices.

Authors: Balneaves, Lynda G., Lee, Richard T., Tomlinson Guns, Emma S., Zick, Suzanna M., Bauer-Wu, Susan, Greenlee, Heather, Zick, S.M., Wyatt, G., Murphy, S., Arnedt, J. T., Ananda, S., Harris, R., Mao, Jun J., Xie, Sharon X., Farrar, John T., Stricker, Carrie T., Bowman, Marjorie A., Bruner, Deborah, DeMichele, Angela, Garland, Sheila N.

Source: Integrative Cancer Therapies; Jan2014, Vol. 13 Issue 1, p5-11, 7p

Age-dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease.

Authors: Mazarei, Gelareh, Budac, David P., Lu, Ge, Adomat, Hans, Tomlinson Guns, Emma S., Möller, Thomas, Leavitt, Blair R.

Source: Journal of Neurochemistry; Dec2013, Vol. 127 Issue 6, p852-867, 16p

Subject Terms: KYNURENINE, LABORATORY mice, HUNTINGTON disease, INDOLEAMINE 2,3-dioxygenase, GENE expression, MESSENGER RNA

A novel oral dosage formulation of the ginsenoside aglycone protopanaxadiol exhibits therapeutic activity against a hormone-insensitive model of prostate cancer.

Authors: Musende, Alain Gulenga, Eberding, Andy, Wood, Catherine A., Adomat, Hans, Fazli, Ladan, Hurtado-Coll, Antonio, Jia, William, Bally, Marcel B., Tomlinson Guns, Emma S.

Source: Anti-Cancer Drugs; Jun2012, Vol. 23 Issue 5, p543-552, 10p

A novel communication role for CYP17A1 in the progression of castration-resistant prostate cancer.

Authors: Locke, Jennifer A., Fazli, Ladan, Adomat, Hans, Smyl, Jil, Weins, Kristin, Lubik, Amy A., Hales, Dale B., Nelson, Colleen C., Gleave, Martin E., Tomlinson Guns, Emma S.

Source: Prostate; Jun2009, Vol. 69 Issue 9, p928-937, 10p

Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue.

Authors: Deb, Subrata, Chin, Mei Yieng, Pham, Steven, Adomat, Hans, Hurtado-Coll, Antonio, Gleave, Martin E., Tomlinson Guns, Emma S.

Source: International Journal of Molecular Sciences; Jan2021, Vol. 22 Issue 2, p487-487, 1p

Subject Terms: PROSTATE cancer, LIQUID chromatography-mass spectrometry, CASTRATION-resistant prostate cancer, PROGESTERONE, PROSTATE, TISSUES, ANDROGEN receptors, DRUG metabolism