PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Authors: Garbicz, Filip ^*, Szumera-Ciećkiewicz, Anna ^*, Barankiewicz, Joanna ^*, Komar, Dorota ^*, Pawlak, Michał ^*, Dębek, Sonia ^*, Matrejek, Aleksandra ^*, Stuehmer, Thorsten ^*, Salomon-Perzynski, Aleksander ^*, Malenda, Agata ^*, Brzózka, Krzysztof, Rzymski, Tomasz ^*, Tomirotti, Andrea Massimiliano ^*, Lech-Marańda, Ewa ^*, Prochorec-Sobieszek, Monika ^*, Szydlowski, Maciej ^*, Juszczynski, Przemyslaw ^*

Source: In Blood 5 November 2020 136 Supplement 1:16-17

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Authors: Szydlowski, Maciej ^*, Garbicz, Filip ^*, Jabłońska, Ewa ^*, Górniak, Patryk ^*, Pyrzynska, Beata ^*, Bojarczuk, Kamil ^*, Komar, Dorota ^*, Prochorec-Sobieszek, Monika ^*, Szumera-Ciećkiewicz, Anna ^*, Rymkiewicz, Grzegorz ^*, Cybulska, Magdalena ^*, Statkiewicz, Małgorzata ^*, Gajewska, Marta ^*, Mikula, MIchał ^*, Golas, Aniela ^*, Domagała, Joanna ^*, Winiarska, Magdalena ^*, Graczyk-Jarzynka, Agnieszka ^*, Bialopiotrowicz, Emilia ^*, Polak, Anna ^*, Barankiewicz, Joanna ^*, Pula, Bartosz ^*, Green, Michael R, Nowis, Dominika ^*, Golab, Jakub ^*, Tomirotti, Andrea Massimiliano ^*, Brzózka, Krzysztof, Pacheco-Blanco, Mariana ^*, Kupcova, Kristyna ^*, Havranek, Ondrej, Chapuy, Bjoern, Juszczynski, Przemyslaw ^*

Source: In Blood 5 November 2020 136 Supplement 1:33-34

SEL24/MEN1703 Provides PIM/FLT3 Downstream Pathway Inhibition in Acute Myeloid Leukemia (AML) Blast Cells: Results of the Pharmacodynamics (PD) Assay in the Dose Escalation Part of First-in-Human Diamond Trial

Authors: Tomirotti, Andrea Massimiliano ^*, Bellarosa, Daniela ^*, Solomon, Scott R., Nazha, Aziz, Strickland, Stephen A, Walter, Roland P, Ravandi, Farhad, Brzózka, Krzysztof, Mazan, Milena ^*, Baldini, Simone ^*, Salerno, Massimiliano ^*, Binaschi, Monica ^*, Laurent, Dirk ^*, Pellacani, Andrea ^*

Source: In Blood 5 November 2020 136 Supplement 1:30-31

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