Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles.

Authors: Flynn, Aidan, Pattison, Andrew D., Balachander, Shiva, Boehm, Emma, Bowen, Blake, Dwight, Trisha, Rossello, Fernando J., Hofmann, Oliver, Martelotto, Luciano, Zethoven, Maia, Kirschner, Lawrence S., Else, Tobias, Fishbein, Lauren, Gill, Anthony J., Tischler, Arthur S., Giordano, Thomas, Prodanov, Tamara, Noble, Jane R., Reddel, Roger R., Trainer, Alison H.

Source: Nature Communications; 3/17/2025, Vol. 16 Issue 1, p1-20, 20p

Subject Terms: MEDICAL sciences, MEDICAL genetics, CHROMAFFIN cells, THERAPEUTICS, NEUROENDOCRINE tumors

Data set for the reporting of pheochromocytoma and paraganglioma: explanations and recommendations of the guidelines from the International Collaboration on Cancer Reporting

Authors: Thompson, Lester D.R., Gill, Anthony J., Asa, Sylvia L., Clifton-Bligh, Roderick J., de Krijger, Ronald R., Kimura, Noriko, Komminoth, Paul, Lack, Ernest E., Lenders, Jacques W.M., Lloyd, Ricardo V., Papathomas, Thomas G., Sadow, Peter M., Tischler, Arthur S.

Source: In Human Pathology April 2021 110:83-97

Targeting pheochromocytoma/paraganglioma with polyamine inhibitors

Authors: Rai, Sudhir Kumar, Bril, Fernando, Hatch, Heather M., Xu, Yiling, Shelton, Laura, Kalavalapalli, Srilaxmi, Click, Arielle, Lee, Douglas, Beecher, Chris, Kirby, Austin, Kong, Kimi, Trevino, Jose, Jha, Abhishek, Jatav, Shashank, Kriti, Kriti, Luthra, Soumya, Garrett, Timothy J., Guingab-Cagmat, Joy, Plant, Daniel, Bose, Prodip, Cusi, Kenneth, Hromas, Robert A., Tischler, Arthur S., Powers, James F., Gupta, Priyanka, Bibb, James, Beuschlein, Felix, Robledo, Mercedes, Calsina, Bruna, Timmers, Henri, Taieb, David, Kroiss, Matthias, Richter, Susan, Langton, Katharina, Eisenhofer, Graeme, Bergeron, Raymond, Jr., Pacak, Karel, Tevosian, Sergei G., Ghayee, Hans K.

Source: In Metabolism September 2020 110

Deletion of the Synaptic Protein Interaction Site of the N-Type ( Ca V2.2) Calcium Channel Inhibits Secretion in Mouse Pheochromocytoma Cells

Authors: Harkins, Amy B., Cahill, Anne L., Powers, James F., Tischler, Arthur S., Fox, Aaron P., Catterall, William A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Oct . 101(42), 15219-15224.

Access URL: https://www.jstor.org/stable/3373603

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

Authors: Akbani, Rehan, Ally, Adrian, Amar, Laurence, Amelio, Antonio L., Arachchi, Harindra, Asa, Sylvia L., Auchus, Richard J., Auman, J. Todd, Baertsch, Robert, Balasundaram, Miruna, Balu, Saianand, Bartsch, Detlef K., Baudin, Eric, Bauer, Thomas, Beaver, Allison, Benz, Christopher, Beroukhim, Rameen, Beuschlein, Felix, Bodenheimer, Tom, Boice, Lori, Bowen, Jay, Bowlby, Reanne, Brooks, Denise, Carlsen, Rebecca, Carter, Suzie, Cassol, Clarissa A., Cherniack, Andrew D., Chin, Lynda, Cho, Juok, Chuah, Eric, Chudamani, Sudha, Cope, Leslie, Crain, Daniel, Curley, Erin, Danilova, Ludmila, de Cubas, Aguirre A., de Krijger, Ronald R., Demchok, John A., Deutschbein, Timo, Dhalla, Noreen, Dimmock, David, Dinjens, Winand N.M., Else, Tobias, Eng, Charis, Eschbacher, Jennifer, Fassnacht, Martin, Felau, Ina, Feldman, Michael, Ferguson, Martin L., Fiddes, Ian, Fishbein, Lauren, Frazer, Scott, Gabriel, Stacey B., Gardner, Johanna, Gastier-Foster, Julie M., Gehlenborg, Nils, Gerken, Mark, Getz, Gad, Geurts, Jennifer, Ghayee, Hans K., Gimenez-Roqueplo, Anne-Paule, Giordano, Thomas J., Goldman, Mary, Graim, Kiley, Gupta, Manaswi, Haan, David, Hahner, Stefanie, Hantel, Constanze, Haussler, David, Hayes, D. Neil, Heiman, David I., Hoadley, Katherine A., Holt, Robert A., Hoyle, Alan P., Huang, Mei, Hunt, Bryan, Hutter, Carolyn M., Jefferys, Stuart R., Johnson, Amy R., Jones, Steven J.M., Jones, Corbin D., Kasaian, Katayoon, Kebebew, Electron, Kim, Jaegil, Kimes, Patrick, Knijnenburg, Theo, Korpershoek, Esther, Lander, Eric, Lawrence, Michael S., Lechan, Ronald, Lee, Darlene, Leraas, Kristen M., Lerario, Antonio, Leshchiner, Ignaty, Lichtenberg, Tara M., Lin, Pei, Ling, Shiyun, Liu, Jia, LiVolsi, Virginia A., Lolla, Laxmi, Lotan, Yair, Lu, Yiling, Ma, Yussanne, Maison, Nicole, Makowski, Liza, Mallery, David, Mannelli, Massimo, Marquard, Jessica, Marra, Marco A., Matthew, Thomas, Mayo, Michael, Méatchi, Tchao, Meng, Shaowu, Merino, Maria J., Mete, Ozgur, Meyerson, Matthew, Mieczkowski, Piotr A., Mills, Gordon B., Moore, Richard A., Morozova, Olena, Morris, Scott, Mose, Lisle E., Mungall, Andrew J., Murray, Bradley A., Naresh, Rashi, Nathanson, Katherine L., Newton, Yulia, Ng, Sam, Ni, Ying, Noble, Michael S., Nwariaku, Fiemu, Pacak, Karel, Parker, Joel S., Paul, Evan, Penny, Robert, Perou, Charles M., Perou, Amy H., Pihl, Todd, Powers, James, Rabaglia, Jennifer, Radenbaugh, Amie, Ramirez, Nilsa C., Rao, Arjun, Rathmell, W. Kimryn, Riester, Anna, Roach, Jeffrey, Robertson, A. Gordon, Sadeghi, Sara, Saksena, Gordon, Salama, Sofie, Saller, Charles, Sandusky, George, Sbiera, Silviu, Schein, Jacqueline E., Schumacher, Steven E., Shelton, Candace, Shelton, Troy, Sheth, Margi, Shi, Yan, Shih, Juliann, Shmulevich, Ilya, Simons, Janae V., Sipahimalani, Payal, Skelly, Tara, Sofia, Heidi J., Sokolov, Artem, Soloway, Matthew G., Sougnez, Carrie, Stuart, Josh, Sun, Charlie, Swatloski, Teresa, Tam, Angela, Tan, Donghui, Tarnuzzer, Roy, Tarvin, Katherine, Thiessen, Nina, Thorne, Leigh B., Timmers, Henri J., Tischler, Arthur S., Tse, Kane, Uzunangelov, Vlado, van Berkel, Anouk, Veluvolu, Umadevi, Vicha, Ales, Voet, Doug, Waldmann, Jens, Walter, Vonn, Wan, Yunhu, Wang, Zhining, Wang, Tracy S., Weaver, Joellen, Weinstein, John N., Weismann, Dirk, Wenz, Brandon, Wilkerson, Matthew D., Wise, Lisa, Wong, Tina, Wong, Christopher, Wu, Ye, Yang, Liming, Zelinka, Tomas, Zenklusen, Jean C., Zhang, Jiashan (Julia), Zhang, Wei, Zhu, Jingchun, Zinzindohoué, Franck, Zmuda, Erik

Source: In Cancer Cell 13 February 2017 31(2):181-193

Hypoxia-Inducible Factor 2α Mutation-Related Paragangliomas Classify as Discrete Pseudohypoxic Subcluster

Authors: Fliedner, Stephanie M.J., Shankavaram, Uma, Marzouca, Geena, Elkahloun, Abdel, Jochmanova, Ivana, Daerr, Roland, Linehan, W. Marston, Timmers, Henri, Tischler, Arthur S., Papaspyrou, Konstantinos, Brieger, Jürgen, de Krijger, Ronald, Breza, Jan, Eisenhofer, Graeme, Zhuang, Zhengping, Lehnert, Hendrik, Pacak, Karel

Source: In Neoplasia September 2016 18(9):567-576

SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T)

Authors: Papathomas, Thomas G, Oudijk, Lindsey, Persu, Alexandre, Gill, Anthony J, van Nederveen, Francien, Tischler, Arthur S, Tissier, Frédérique, Volante, Marco, Matias-Guiu, Xavier, Smid, Marcel, Favier, Judith, Rapizzi, Elena, Libe, Rosella, Currás-Freixes, Maria, Aydin, Selda, Huynh, Thanh, Lichtenauer, Urs, van Berkel, Anouk, Canu, Letizia, Domingues, Rita, Clifton-Bligh, Roderick J, Bialas, Magdalena, Vikkula, Miikka, Baretton, Gustavo, Papotti, Mauro, Nesi, Gabriella, Badoual, Cécile, Pacak, Karel, Eisenhofer, Graeme, Timmers, Henri J, Beuschlein, Felix, Bertherat, Jérôme, Mannelli, Massimo, Robledo, Mercedes, Gimenez-Roqueplo, Anne-Paule, Dinjens, Winand NM, Korpershoek, Esther, de Krijger, Ronald R

Source: In Modern Pathology June 2015 28(6):807-821

"Strumal Carcinoid": A Well-Described but Unexplained Intratumoral Tumor.

Authors: Ualiyeva, Saltanat, Panchal, Maharshi, Basu, Atreyee, Tischler, Arthur S.

Source: Endocrine Pathology; Jun2024, Vol. 35 Issue 2, p158-160, 3p

Insights Obtained from the Nontumorous Glandular Tissue in Patients with Endocrine Tumors.

Authors: Tischler, Arthur S., LiVolsi, Virginia A., Asa, Sylvia L.

Source: Endocrine Pathology; Dec2023, Vol. 34 Issue 4, p393-405, 13p

Genotype and Tumor Locus Determine Expression Profile of Pseudohypoxic Pheochromocytomas and Paragangliomas

Authors: Shankavaram, Uma, Fliedner, Stephanie M.J., Elkahloun, Abdel G., Barb, Jenifer J., Munson, Peter J., Huynh, Thanh T., Matro, Joey C., Turkova, Hana, Linehan, W. Marston, Timmers, Henri J., Tischler, Arthur S., Powers, James F., de Krijger, Ronald, Baysal, Bora E., Takacova, Martina, Pastorekova, Silvia, Gius, David, Lehnert, Hendrik, Camphausen, Kevin, Pacak, Karel

Source: In Neoplasia April 2013 15(4):435

Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging

Authors: Giubellino, Alessio, Woldemichael, Girma M., Sourbier, Carole, Lizak, Martin J., Powers, James F., Tischler, Arthur S., Pacak, Karel

Source: In Cancer Letters 2012 316(1):46-52

Progress and challenges in experimental models for pheochromocytoma and paraganglioma.

Authors: Tischler, Arthur S.¹ atischler@tuftsmedicalcenter.org, Favier, Judith²

Source: Endocrine-Related Cancer. May2023, Vol. 30 Issue 5, p58-63. 6p.

Subject Terms: *PARAGANGLIOMA, *PHEOCHROMOCYTOMA, *DRUG efficacy, *TISSUE culture, *CELL populations, *CLINICAL drug trials

Establishment of a Noradrenergic Clonal Line of Rat Adrenal Pheochromocytoma Cells which Respond to Nerve Growth Factor

Authors: Greene, Lloyd A., Tischler, Arthur S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1976 Jul 01. 73(7), 2424-2428.

Access URL: https://www.jstor.org/stable/65785

Transcriptional silencing of glucocorticoid-inducible phenylethanolamine N-methyltransferase expression by sequential signaling events

Authors: Evinger, Marian J., Powers, James F., Tischler, Arthur S.

Source: In Experimental Cell Research 2007 313(4):772-781

Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment.

Authors: Zethoven, Magnus, Martelotto, Luciano, Pattison, Andrew, Bowen, Blake, Balachander, Shiva, Flynn, Aidan, Rossello, Fernando J., Hogg, Annette, Miller, Julie A., Frysak, Zdenek, Grimmond, Sean, Fishbein, Lauren, Tischler, Arthur S., Gill, Anthony J., Hicks, Rodney J., Dahia, Patricia L. M., Clifton-Bligh, Roderick, Pacak, Karel, Tothill, Richard W.

Source: Nature Communications; 10/21/2022, Vol. 13 Issue 1, p1-18, 18p

Subject Terms: TUMOR microenvironment, PARAGANGLIOMA, PHEOCHROMOCYTOMA, CHROMAFFIN cells, NEUROENDOCRINE tumors, CELL nuclei

Microarray-based comparative genomic hybridization of pheochromocytoma cell lines from neurofibromatosis knockout mice reveals genetic alterations similar to those in human pheochromocytomas

Authors: Powers, James F., Tischler, Arthur S., Mohammed, Mansoor, Naeem, Rizwann

Source: In Cancer Genetics and Cytogenetics 2005 159(1):27-31

GDNF-induced leukemia inhibitory factor can mediate differentiation via the MEK/ERK pathway in pheochromocytoma cells derived from nf1-heterozygous knockout mice

Authors: Park, Jong-In ^*, Powers, James F., Tischler, Arthur S., Strock, Christopher J., Ball, Douglas W., Nelkin, Barry D.

Source: In Experimental Cell Research 2005 303(1):79-88

Neural Properties of Cultured Human Endocrine Tumor Cells of Proposed Neural Crest Origin

Authors: Tischler, Arthur S., Dichter, Marc A., Biales, Bernard, DeLellis, Ronald A., Wolfe, Hubert

Source: Science, 1976 May . 192(4242), 902-904.

Access URL: https://www.jstor.org/stable/1742157

Middle Ear "Adenoma": a Neuroendocrine Tumor with Predominant L Cell Differentiation.

Authors: Asa, Sylvia L., Arkun, Knarik, Tischler, Arthur S., Qamar, Adnan, Deng, Fang-Ming, Perez-Ordonez, Bayardo, Weinreb, Ilan, Bishop, Justin A., Wenig, Bruce M., Mete, Ozgur

Source: Endocrine Pathology; Dec2021, Vol. 32 Issue 4, p433-441, 9p

High-Level Expression of Receptor Tyrosine Kinase Ret and Responsiveness to Ret-Activating Ligands in Pheochromocytoma Cell Lines from Neurofibromatosis Knockout Mice

Authors: Powers, James F. ^{1 1 To whom correspondence and reprint requests should be addressed. Fax: 617-636-8302. E-mail: jpowersl@lifespan.org.}, Schelling, Kimberley, Brachold, Jaime M., Tsokas, Panayiotis, Schayek, Hagit, Friedman, Eitan, Tischler, Arthur S.

Source: In Molecular and Cellular Neuroscience 2002 20(3):382-389