Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy

Authors: Ting-Yu Chang, Chun-Jung Lin, Shih-Ni Wen, Yi-Chen Wu, Cheng-Yen Wei, Jye-Yu Huang, Yu-Hsuan Tsao, Yu-Jung Chen, Wei-Chien Tang, Yuen-Chin Wu, Wei-Han Lee, Teng-Yi Huang, Tzer-Min Kuo, Wan-Fen Li, Ming-Tain Lai

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-14 (2025)

Subject Terms: TROP2, Topoisomerase I inhibitors, OBI-992, Antibody–drug conjugate, Exatecan, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/220b289df815499d97cf0d332ca5e0c9

Post-irradiation vertebral and carotid stenosis heightens stroke risk in head and neck cancer

Authors: Jian-Lin Jiang, Joseph Tung-Chieh Chang, Bing-Shen Huang, Ting-Yu Chang, Pi-Shan Sung, Yi-Chia Wei, Chien-Yu Lin, Chih-Hua Yeh, Kang-Hsing Fan, Chi-Hung Liu

Source: BMC Cancer, Vol 25, Iss 1, Pp 1-12 (2025)

Subject Terms: Carotid artery stenosis, Head and neck cancer, Ischemic stroke, Radiation therapy, Vertebral artery stenosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/0f119a9151cf44e2890f5104be67977c

A multitask deep learning model utilizing electrocardiograms for major cardiovascular adverse events prediction

Authors: Ching-Heng Lin, Zhi-Yong Liu, Pao-Hsien Chu, Jung-Sheng Chen, Hsin-Hsu Wu, Ming-Shien Wen, Chang-Fu Kuo, Ting-Yu Chang

Source: npj Digital Medicine, Vol 8, Iss 1, Pp 1-10 (2025)

Subject Terms: Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/2398-6352

Access URL: https://doaj.org/article/0d4722468b3c4d61bbd4301f5221255e

Genetic investigations of autosomal recessive inherited ichthyosis impressed by fetal ultrasound: Exome sequencing and haplotype linkage analysis

Authors: Ting-Yu Chang, Zhu Wei Lim, Yi-Tzu Chu, Wan-Ju Wu, Mei-Hui Lee, Shun-Ping Chang, Dong-Jay Lee, Wen-Hsiang Lin, Ming Ho, Jin-Chung Shih, Gwo-Chin Ma, Ming Chen

Source: Taiwanese Journal of Obstetrics & Gynecology, Vol 64, Iss 1, Pp 53-60 (2025)

Subject Terms: Harlequin ichthyosis, ABCA12, WES, Linkage analysis, Unequal coverage, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1028455924002778; https://doaj.org/toc/1028-4559

Access URL: https://doaj.org/article/fd6f0105a62a4e5f9506f52b8732e844

Abdominal ultrasound stimulation alleviates DSS-induced colitis and behavioral disorders in mice by mediating the microbiota–gut–brain axis balance

Authors: Cong-Yong Gao, Yi-Ju Pan, Wei-Shen Su, Chun-Yi Wu, Ting-Yu Chang, Feng-Yi Yang

Source: Neurotherapeutics, Vol 22, Iss 2, Pp e00494- (2025)

Subject Terms: Abdominal ultrasound, IBD, Intestinal inflammation, Neuroinflammation, Microbiota, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1878747924001818; https://doaj.org/toc/1878-7479

Access URL: https://doaj.org/article/74296a7fed514420ba3dc8919c3337ca

Biomechanical analysis of four different meniscus suturing techniques for posterior meniscal root pull‐out repair: A human cadaveric study

Authors: Ting‐Yu Chang, Tai‐Hua Yang, Kuan‐Yu Lin

Source: Journal of Experimental Orthopaedics, Vol 11, Iss 3, Pp n/a-n/a (2024)

Subject Terms: knee, meniscus root, pull‐out repair, root tear, slip‐knot, Orthopedic surgery, RD701-811

File Description: electronic resource

Relation: https://doaj.org/toc/2197-1153

Access URL: https://doaj.org/article/3be9e7e61a924be599ae70119d313bef

Perfusion Profiles May Differ Between Asymptomatic Versus Symptomatic Internal Carotid Artery Occlusion

Authors: Ting-Yu Chang, Soren Christensen, Michael Mlynash, Jeremy J. Heit, Michael P. Marks, Sarah Lee, Margy E. McCullough-Hicks, Lili Velickovic Ostojic, Stephanie Kemp, Gregory W. Albers, Aditya Srivatsan, Tsong-Hai Lee, Maarten G. Lansberg

Source: Journal of Stroke, Vol 26, Iss 1, Pp 108-111 (2024)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.j-stroke.org/upload/pdf/jos-2023-02768.pdf; https://doaj.org/toc/2287-6391; https://doaj.org/toc/2287-6405

Access URL: https://doaj.org/article/cdca1d1743b747dda290899f4a844772

Risk of temporal lobe necrosis between proton beam and volumetric modulated arc therapies in patients with different head and neck cancers

Authors: Chi-Hung Liu, Chien-Yu Lin, Bing-Shen Huang, Yi-Chia Wei, Ting-Yu Chang, Chih-Hua Yeh, Pi-Shan Sung, Jian-Lin Jiang, Li-Ying Lin, Joseph Tung-Chieh Chang, Kang-Hsing Fan

Source: Radiation Oncology, Vol 18, Iss 1, Pp 1-11 (2023)

Subject Terms: Temporal lobe necrosis, Head and neck cancer, Nasopharyngeal carcinoma, Radiation therapy, Proton therapy, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1748-717X

Access URL: https://doaj.org/article/a8531310832d4b309386f1691de40a3e

Incidence of Carotid Blowout Syndrome in Patients with Head and Neck Cancer after Radiation Therapy: A Cohort Study

Authors: Jian-Lin Jiang, Joseph Tung-Chieh Chang, Chih-Hua Yeh, Ting-Yu Chang, Bing-Shen Huang, Pi-Shan Sung, Chien-Yu Lin, Kang-Hsing Fan, Yi-Chia Wei, Chi-Hung Liu

Source: Diagnostics, Vol 14, Iss 12, p 1222 (2024)

Subject Terms: carotid blowout syndrome, head and neck cancer, nasopharyngeal carcinoma, pseudoaneurysm, radiation therapy, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/14/12/1222; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/84db3dbb70194055b4511acc3365f42b

Synergistic Insecticidal Effect of Photorhabdus luminescens and Bacillus thuringiensis against Fall Armyworm (Spodoptera frugiperda)

Authors: Ting-Yu Chang, Chienyan Hsieh, Li-Hsin Wu

Source: Agriculture, Vol 14, Iss 6, p 864 (2024)

Subject Terms: entomopathogenic nematode symbiotic bacteria, combination formulations, histopathology section, pesticide reduction, Agriculture (General), S1-972

File Description: electronic resource

Relation: https://www.mdpi.com/2077-0472/14/6/864; https://doaj.org/toc/2077-0472

Access URL: https://doaj.org/article/15de34aa72d34cbca97e8b74a95c04d1

Automatic identification of early ischemic lesions on non-contrast CT with deep learning approach

Authors: Prasan Kumar Sahoo, Sulagna Mohapatra, Ching-Yi Wu, Kuo-Lun Huang, Ting-Yu Chang, Tsong-Hai Lee

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8fb05c8c025645b8835636d24caaac8a

Effects of woven structure and impact mode on the low-velocity impact properties and fractography of bamboo-textile-reinforced polymer composites

Authors: Chun-Wei Chang, Ya-Yu Lu, Tsung-Han Hsieh, Ting-Yu Chang, Feng-Cheng Chang

Source: Polymer Testing, Vol 123, Iss , Pp 108043- (2023)

Subject Terms: Fabrics/textiles, Impact behavior, Fractography, 3D X-ray, Polymers and polymer manufacture, TP1080-1185

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S014294182300123X; https://doaj.org/toc/0142-9418

Access URL: https://doaj.org/article/0f270af7d5514739b99667f7d3bf6034

In vitro genotoxicity assessment and 28-day repeated dose oral toxicity study of steady-calcium formula in rats

Authors: Ting-Yu Chang, Kuo-Cheng Lan, Kuo-Tai Hua, Shing-Hwa Liu

Source: Toxicology Reports, Vol 9, Iss , Pp 834-841 (2022)

Subject Terms: Functional food mixture, Genotoxicity, Chromosomal aberrations, Clastogenicity, 28-day repeated dose oral toxicity, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750022000907; https://doaj.org/toc/2214-7500

Access URL: https://doaj.org/article/c394ced93f7a4bdc913432c702070060

Inhibition of Indoxyl Sulfate-Induced Reactive Oxygen Species-Related Ferroptosis Alleviates Renal Cell Injury In Vitro and Chronic Kidney Disease Progression In Vivo

Authors: Li-Ting Tsai, Te-I Weng, Ting-Yu Chang, Kuo-Cheng Lan, Chih-Kang Chiang, Shing-Hwa Liu

Source: Antioxidants, Vol 12, Iss 11, p 1931 (2023)

Subject Terms: indoxyl sulfate, ferroptosis, ROS, fibrosis, chronic kidney disease, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/11/1931; https://doaj.org/toc/2076-3921

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Comprehensive Investigation of Constant Voltage Stress Time-Dependent Breakdown and Cycle-to-Breakdown Reliability in Y-Doped and Si-Doped HfO2 Metal-Ferroelectric-Metal Memory

Authors: Ting-Yu Chang, Kuan-Chi Wang, Hsien-Yang Liu, Jing-Hua Hseun, Wei-Cheng Peng, Nicolò Ronchi, Umberto Celano, Kaustuv Banerjee, Jan Van Houdt, Tian-Li Wu

Source: Nanomaterials, Vol 13, Iss 14, p 2104 (2023)

Subject Terms: ferroelectric, domain size, reliability, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/13/14/2104; https://doaj.org/toc/2079-4991

Access URL: https://doaj.org/article/91fc261f328846a89ac69a003a88a21d

Mediating roles of leukoaraiosis and infarcts in the effects of unilateral carotid artery stenosis on cognition

Authors: Kuo-Lun Huang, Ting-Yu Chang, Yi-Ming Wu, Yeu-Jhy Chang, Hsiu-Chuan Wu, Chi-Hung Liu, Tsong-Hai Lee, Meng-Yang Ho

Source: Frontiers in Aging Neuroscience, Vol 14 (2022)

Subject Terms: cognition, carotid artery stenosis (CAS), leukoaraiosis (LA), infarct, mediation analysis, white matter hyperintensities, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2022.972480/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/2c64a591716f48eea7a8b9fca33c42c7

Parallel processing, hierarchical transformations, and sensorimotor associations along the ‘where’ pathway

Authors: Raymond Doudlah, Ting-Yu Chang, Lowell W Thompson, Byounghoon Kim, Adhira Sunkara, Ari Rosenberg

Source: eLife, Vol 11 (2022)

Subject Terms: 3D vision, oculomotor, saccade, choice, sensorimotor, parieto-occipital junction, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/78712; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/99a124aa1e2f41ea81f5ddd3cd2e128f

Concurrent use of statins decreases major bleeding and intracerebral hemorrhage in non-valvular atrial fibrillation patients taking direct oral anticoagulants—A nationwide cohort study

Authors: Hsin-Hsu Wu, Shang-Hung Chang, Tsong-Hai Lee, Hui-Tzu Tu, Chi-Hung Liu, Ting-Yu Chang

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Subject Terms: atrial fibrillation, DOACs, direct-acting oral anticoagulant, major bleeding, intracerebral hemorrhage, statin, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.969259/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/4051f4793d28485999f14ffcf7323615

Hypothyroidism and risks of cerebrovascular complications among patients with head and neck cancer after radiotherapy

Authors: Chi-Hung Liu, Joseph Tung-Chieh Chang, Tsong-Hai Lee, Pi-Yueh Chang, Chien-Hung Chang, Hsiu-Chuan Wu, Ting-Yu Chang, Kuo-Lun Huang, Chien-Yu Lin, Kang-Hsing Fan, Yeu-Jhy Chang

Source: BMC Neurology, Vol 21, Iss 1, Pp 1-8 (2021)

Subject Terms: Carotid artery stenosis, Head and neck cancer, Hypothyroidism, Ischemic stroke, Radiation therapy, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/ebf086796e184bf3b0b413e1edd20ca3

TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s disease

Authors: Yao-Hsiang Shih, Ling-Hsien Tu, Ting-Yu Chang, Kiruthika Ganesan, Wei-Wei Chang, Pao-Sheng Chang, Yu-Sheng Fang, Yeh-Tung Lin, Lee-Way Jin, Yun-Ru Chen

Source: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a3987a249bec4a6a993488d9681fbc13