Expression, purification and crystallization of a novel metagenome‐derived salicylaldehyde dehydrogenase from Alpine soil

Authors: Dandare, Shamsudeen Umar, Håkansson, Maria, Svensson, L. Anders, Timson, David J., Allen, Christopher C. R.

Source: Acta crystallographica.Section F.Structural biology communications. 78(4):161-169

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The structural and molecular biology of type IV galactosemia

Authors: Banford, Samantha, Timson, David J.

Source: In Biochimie April 2021 183:13-17

Galactokinase deficiency: lessons from the GalNet registry

Authors: Rubio-Gozalbo, M. Estela, Derks, Britt, Das, Anibh Martin, Meyer, Uta, Möslinger, Dorothea, Couce, M. Luz, Empain, Aurélie, Ficicioglu, Can, Juliá Palacios, Natalia, De Los Santos De Pelegrin, Mariela M., Rivera, Isabel A., Scholl-Bürgi, Sabine, Bosch, Annet M., Cassiman, David, Demirbas, Didem, Gautschi, Matthias, Knerr, Ina, Labrune, Philippe, Skouma, Anastasia, Verloo, Patrick, Wortmann, Saskia B., Treacy, Eileen P., Timson, David J., Berry, Gerard T.

Source: In Genetics in Medicine January 2021 23(1):202-210

[13C]‐galactose breath test in a patient with galactokinase deficiency and spastic diparesis

Authors: Ficicioglu, Can, Demirbas, Didem, Derks, Britt, Pai, G. Shashidhar, Timson, David J., Rubio‐Gozalbo, Maria Estela, Berry, Gerard T.

Source: JIMD reports. 59(1):104-109

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RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development

Authors: McCusker, Paul, Hussain, Wasim, McVeigh, Paul, McCammick, Erin, Clarke, Nathan G., Robb, Emily, McKay, Fiona M., Brophy, Peter M., Timson, David J., Mousley, Angela, Marks, Nikki J., Maule, Aaron G.

Source: In International Journal for Parasitology: Drugs and Drug Resistance December 2020 14:46-55

The Schistosoma mansoni tegumental allergen protein, SmTAL1: Binding to an IQ-motif from a voltage-gated ion channel and effects of praziquantel

Authors: Thomas, Charlotte M., Timson, David J. ^*

Source: In Cell Calcium March 2020 86

Dynamic origins of substrate promiscuity in bacterial galactokinases

Authors: McAuley, Margaret, Huang, Meilan, Timson, David J.

Source: In Carbohydrate Research 1 December 2019 486

NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms

Authors: Beaver, Sarah K., Mesa-Torres, Noel, Pey, Angel L., Timson, David J.

Source: In BBA - Proteins and Proteomics July-August 2019 1867(7-8):663-676

In Silico Analysis of the Effects of Point Mutations on α-Globin: Implications for α-Thalassemia

Authors: Horri-Naceur, Agathe, Timson, David J.

Source: Hemoglobin. 44(2):89-103

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Praziquantel: An Enigmatic, Yet Effective, Drug

Authors: Timson, David J.

Source: Methods in molecular biology. 2151:1-8

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The Mechanism of Action of Praziquantel: Can New Drugs Exploit Similar Mechanisms?

Authors: Thomas, Charlotte M., Timson, David J.

Source: Current medicinal chemistry. 27(5):676-696

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105402519.0x000001&indx=1&recIds=ETOCvdc_100105402519.0x000001

Therapies for galactosemia: a patent landscape

Authors: Timson, David J

Source: Pharmaceutical patent analyst. 9(2):45-51

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Destressing Yeast for Higher Biofuel Yields: Can Excess Chaotropicity Be Mitigated?

Authors: Timson, David J., Eardley, Joshua

Source: Applied biochemistry and biotechnology. 192(4):1368-1375

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New model for the interaction of IQGAP1 with CDC42 and RAC1

Authors: Nouri, Kazem, Timson, David J., Ahmadian, Mohammad R.

Source: Small GTPases. 11(1):16-22

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097994922.0x000001&indx=1&recIds=ETOCvdc_100097994922.0x000001

Modulation of the mobility of a key region in human galactokinase: Impacts on catalysis and stability

Authors: McAuley, Margaret, Huang, Meilan, Timson, David J.

Source: In Bioorganic Chemistry December 2018 81:649-657

Calmodulins from Schistosoma mansoni: Biochemical analysis and interaction with IQ-motifs from voltage-gated calcium channels

Authors: Thomas, Charlotte M., Timson, David J.

Source: In Cell Calcium September 2018 74:1-13

A galactokinase-like protein from the liver fluke Fasciola hepatica

Authors: Zinsser, Veronika L., Cox, Ciara, McAuley, Margaret, Hoey, Elizabeth M., Trudgett, Alan, Timson, David J.

Source: In Experimental Parasitology September 2018 192:65-72

The tegumental allergen-like proteins of Schistosoma mansoni: A biochemical study of SmTAL4-TAL13

Authors: Carson, Jack, Thomas, Charlotte M., McGinty, Aaron, Takata, Gustavo, Timson, David J.

Source: In Molecular & Biochemical Parasitology April 2018 221:14-22

We Are All Mutants

Authors: Timson, David J.

Source: School Science Review. Sep 2017 99(366):45-50.

Peer Reviewed: Y

Page Count: 6

Descriptors: Science Instruction, Genetic Disorders, Genetics, Pregnancy, Diseases, Disabilities, Ethics, Value Judgment, Down Syndrome, Foreign Countries

Geographic Terms: Singapore, United Kingdom, United States

Access URL: https://www.ase.org.uk/journals/school-science-review/2017/10/366/

Characterization of Calcium-Binding Proteins from Parasitic Worms

Authors: Thomas, Charlotte M., Timson, David J.

Source: Methods in molecular biology. 1929:615-644

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