Obesity and hormonal influences on asthma: Mechanisms, management challenges, and emerging therapeutic strategies

Authors: Weare-Regales, Natalia, Carr, Tara, Holguin, Fernando, Tibbitt, Christopher Andrew, Lockey, Richard F.

Source: In The Journal of Allergy and Clinical Immunology December 2024 154(6):1355-1368

Innate lymphoid cells type 2 and CD8+ T cells are perturbed in overweight and obese individuals with asthma

Authors: Björkander, Sophia, Maier, Paul, Kere, Maura, Merid, Simon Kebede, Wirth, Lorenz, Wiegel, Whitney, Ekström, Sandra, Kull, Inger, Bergström, Anna, Melén, Erik, Mjösberg, Jenny, Tibbitt, Christopher Andrew

Source: Allergy. 78(9):2533-2536

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191682040.0x000001&indx=1&recIds=ETOCvdc_100191682040.0x000001

PH sensing shapes immune cell function: The role of GPR65 and its implications for allergic disease

Authors: Souza Ferreira, Sabrina, Bek, Marie Kaarup, Tibbitt, Christopher Andrew

Source: Allergy. 78(7):2061-2063

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186395217.0x000001&indx=1&recIds=ETOCvdc_100186395217.0x000001

Obese asthma phenotypes display distinct plasma biomarker profiles

Authors: Björkander, Sophia, Klevebro, Susanna, Hernandez‐Pacheco, Natalia, Kere, Maura, Ekström, Sandra, Sparreman Mikus, Maria, Hage, Marianne, James, Anna, Kull, Inger, Bergström, Anna, Mjösberg, Jenny, Tibbitt, Christopher Andrew, Melén, Erik

Source: Clinical and translational allergy. 13(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181669250.0x000001&indx=1&recIds=ETOCvdc_100181669250.0x000001

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells

Authors: Tibbitt, Christopher Andrew, Stark, Julian Mario, Martens, Liesbet, Ma, Junjie, Mold, Jeff Eron, Deswarte, Kim, Oliynyk, Ganna, Feng, Xiaogang, Lambrecht, Bart Norbert, De Bleser, Pieter, Nylén, Susanne, Hammad, Hamida, Arsenian Henriksson, Marie, Saeys, Yvan, Coquet, Jonathan Marie

Source: In Immunity 16 July 2019 51(1):169-184

Innate lymphoid cells type 2 and CD8⁺ T cells are perturbed in overweight and obese individuals with asthma.

Authors: Björkander, Sophia, Maier, Paul, Kere, Maura, Merid, Simon Kebede, Wirth, Lorenz, Wiegel, Whitney, Ekström, Sandra, Kull, Inger, Bergström, Anna, Melén, Erik, Mjösberg, Jenny, Tibbitt, Christopher Andrew

Source: Allergy; Sep2023, Vol. 78 Issue 9, p2533-2536, 4p

Subject Terms: INNATE lymphoid cells, T cells, ASTHMA, OBESITY, MONONUCLEAR leukocytes

pH sensing shapes immune cell function: The role of GPR65 and its implications for allergic disease.

Authors: de Souza Ferreira, Sabrina, Bek, Marie Kaarup, Tibbitt, Christopher Andrew

Source: Allergy; Jul2023, Vol. 78 Issue 7, p2061-2063, 3p

Subject Terms: CELL physiology, CELL morphology, ALLERGIES, INFLAMMATORY bowel diseases, CYCLIC adenylic acid, THYMIC stromal lymphopoietin, HISTIDINE

CD45RA⁺CD62L⁻ ILCs in human tissues represent a quiescent local reservoir for the generation of differentiated ILCs.

Authors: Kokkinou, Efthymia, Pandey, Ram Vinay, Mazzurana, Luca, Gutierrez-Perez, Irene, Tibbitt, Christopher Andrew, Weigel, Whitney, Soini, Tea, Carrasco, Anna, Rao, Anna, Nagasawa, Maho, Bal, Suzanne M., Jangard, Mattias, Friberg, Danielle, Lindforss, Ulrik, Nordenvall, Caroline, Ljunggren, Malin, Haapaniemi, Staffan, Keita, Åsa V., Söderholm, Johan, Hedin, Charlotte

Source: Science Immunology; 2022, Vol. 7 Issue 70, p1-18, 18p

The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis

Authors: Kokkinou, Efthymia, Soini, Tea, Pandey, Ram Vinay, van Acker, Aline, Theorell, Jakob, Czarnewski, Paulo, Kvedaraite, Egle, Vandamme, Niels, Lourda, Magda, Sorini, Chiara, Weigel, Whitney, Carrasco, Anna, Tibbitt, Christopher Andrew, Schlums, Heinrich, Lindforss, Ulrik, Nordenvall, Caroline, Ljunggren, Malin, Ideström, Maja, Svensson, Mattias, Henter, Jan-Inge, Villablanca, Eduardo J., Bryceson, Yenan T., Rolandsdotter, Helena, Mjösberg, Jenny

Source: Cell Reports Medicine; May 2023, Vol. 4 Issue: 5