Cancer-associated fibroblasts reveal aberrant DNA methylation across different types of cancer

Authors: Marco Schmidt, Tiago Maié, Thorsten Cramer, Ivan G. Costa, Wolfgang Wagner

Source: Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)

Subject Terms: Biomarker, Cancer-associated fibroblasts, DNA methylation, Epigenetic, Human, CpG, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/5459e1729ab14efc8979c858d59b47ba

Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms

Authors: Kristin Holl, Nicolas Chatain, Susanne Krapp, Julian Baumeister, Tiago Maié, Sarah Schmitz, Anja Scheufen, Nathalie Brock, Steffen Koschmieder, Daniel Moreno-Andrés

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/16908be3238c4f509fba9b2239b81661

EphrinA5 regulates cell motility by modulating Snhg15/DNA triplex-dependent targeting of DNMT1 to the Ncam1 promoter

Authors: Can Bora Yildiz, Tathagata Kundu, Julia Gehrmann, Jannis Koesling, Amin Ravaei, Philip Wolff, Florian Kraft, Tiago Maié, Mira Jakovcevski, Daniel Pensold, Olav Zimmermann, Giulia Rossetti, Ivan G. Costa, Geraldine Zimmer-Bensch

Source: Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-19 (2023)

Subject Terms: DNA methylation, Nuclear actions of Snhg15, Long non-coding RNA, RNA/DNA triple helix, Cell migration, Medulloblastoma, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/243a1b4e0c1c4caf93c65b9f83fff63e

CimpleG: finding simple CpG methylation signatures

Authors: Tiago Maié, Marco Schmidt, Myriam Erz, Wolfgang Wagner, Ivan G. Costa

Source: Genome Biology, Vol 24, Iss 1, Pp 1-28 (2023)

Subject Terms: DNA methylation, Signature selection, Deconvolution, Clinical application, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/44fe6c4f6b214e30a67685fc48045617

P653: CML LONG-TERM LEUKEMIC STEM CELL PERSISTENCE IS INFLUENCED BY MYELOFIBROSIS AT DIAGNOSIS

Authors: Henrike Jacobi, Margherita Vieri, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Nicolas Chatain, Fabian Beier, Michael Huber, Martina Crysandt, Tim H. Brümmendorf, Mirle Schemionek-Reinders

Source: HemaSphere, Vol 7, p e8231722 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000969516.82317.22; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/76f95e3c7a8948be84aeebe6a888ad80

Myelofibrosis at diagnosis is associated with the failure of treatment-free remission in CML patients

Authors: Henrike Jacobi, Margherita Vieri, Marlena Bütow, Carolina Y. Namasu, Laura Flüter, Ivan G. Costa, Tiago Maié, Katharina Lindemann-Docter, Nicolas Chatain, Fabian Beier, Michael Huber, Wolfgang Wagner, Martina Crysandt, Tim H. Brümmendorf, Mirle Schemionek

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: CML, TFR, fibrosis, leukemic stem cells, LSC, MSc, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1212392/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/1bcfdb9e48a74693a9367baef6ba229c

Targeting cytokine-induced leukemic stem cell persistence in chronic myeloid leukemia by IKK2-inhibition

Authors: Marlena Bütow, Fabio J. Testaquadra, Julian Baumeister, Tiago Maié, Nicolas Chatain, Timo Jaquet, Stefan Tillmann, Martina Crysandt, Ivan G. Costa, Tim H. Brümmendorf, Mirle Schemionek

Source: Haematologica, Vol 108, Iss 4 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10885; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/812b73c5e1934e12ae3523cb4a8c88ae

Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha

Authors: Claudia Schubert, Manuel Allhoff, Stefan Tillmann, Tiago Maié, Ivan G. Costa, Daniel B. Lipka, Mirle Schemionek, Kristina Feldberg, Julian Baumeister, Tim H. Brümmendorf, Nicolas Chatain, Steffen Koschmieder

Source: Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-16 (2019)

Subject Terms: IFNa, BCR-ABL, JAK2V617F, MPN, Polycythemia vera, Chronic myeloid leukemia, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-019-0722-9; https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/f04572cd8a7a47c1b8bb12f8129e168b