Evaluation of thrombospondin 1 as a novel biomarker in pediatric-onset systemic lupus erythematosus

Authors: Chenxi Liu, Menglan Zhang, Lingyi Yan, Jie Luo, Zhijun Liu, Ting Liu, Yongmei Jiang

Source: BMC Pediatrics, Vol 25, Iss 1, Pp 1-9 (2025)

Subject Terms: Pediatric-onset systemic lupus erythematosus, Thrombospondin 1, Biomarker, Correlation, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2431

Access URL: https://doaj.org/article/8b3231a0dfa44579a49bcbc2af2680b0

THBS1 is a new autosomal recessive non-syndromic hearing impairment gene

Authors: Thashi Bharadwaj, Anushree Acharya, Fati Ullah Khan, Saadullah Khan, Irfan Ullah, Isabelle Schrauwen, Wasim Ahmad, Suzanne M. Leal

Source: BMC Medical Genomics, Vol 17, Iss 1, Pp 1-7 (2024)

Subject Terms: Autosomal recessive non-syndromic hearing impairment, Consanguinity, Exome sequencing, Inner ear, Thrombospondin, THBS1, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/84d50ec2ee0f465c9fe8633c54dbc0e1

Circulating thrombospondin 2 as a predictor of hepatocellular carcinoma in hepatitis B patients undergoing nucleos(t)ide analog therapy

Authors: Taiki Okumura, Takefumi Kimura, Yuki Ichikawa, Takanobu Iwadare, Shun-ichi Wakabayashi, Hiroyuki Kobayashi, Yuki Yamashita, Takuro Uchida, Sai P. Pydi, Naoki Tanaka, Takeji Umemura

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Hepatitis B, Nucleos(t)ide analog, Hepatocellular carcinoma, Thrombospondin 2, Biomarker, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/efbf9c3f37394982aa014cb4798abd89

Annual trends in atypical haemolytic uremic syndrome management in Japan and factors influencing early diagnosis and treatment: a retrospective study

Authors: Yoshitaka Tatematsu, Takahiro Imaizumi, Nobuaki Michihata, Noritoshi Kato, Ryosuke Kumazawa, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Shoichi Maruyama

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Atypical haemolytic uremic syndrome (aHUS), Thrombotic microangiopathy (TMA), Eculizumab, Plasma exchange, A disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13 (ADAMTS13), Thrombocytopenia, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/87308da8e3544269b6ee9fd6e8912eae

Differential responses to thrombospondin-1 and PDGF-BB in smooth muscle cells from atherosclerotic coronary arteries and internal thoracic arteries

Authors: Alokkumar S. Pathak, George A. Stouffer

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Smooth muscle, Thrombospondin, Internal thoracic, Atherosclerosis, PDGF-BB, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0fa4856e1ea54e97a8a918d85f27ba31

ADAMTS13 attenuates renal fibrosis by suppressing thrombospondin 1 mediated TGF-β1/Smad3 activation

Authors: Guo, Jie ^{a, 1}, Zhou, Suhan ^{a, 1}, Wang, Honghong ^a, Qiu, Xingyu ^a, Dong, Fang ^a, Jiang, Shan ^a, Xu, Nan ^{a, b}, Cui, Yu ^a, Liu, Ruisheng ^c, Li, Pengyun ^{d, ⁎}, Ma, Zufu ^{e, ⁎}, Zhao, Liang ^{f, ⁎}, Lai, En Yin ^{a, ⁎}

Source: In Toxicology and Applied Pharmacology March 2025 496

Prevalence and prognosis of malignancy in THSD7A-associated membranous nephropathy: a systematic literature review and clinical case study

Authors: Qianqian Xu, Jiayi Li, Yue Yang, Li Zhuo, Hongmei Gao, Shimin Jiang, Wenge Li

Source: Renal Failure, Vol 46, Iss 1 (2024)

Subject Terms: Malignancy, membranous nephropathy, anti-phospholipase A2 receptor antibody, thrombospondin type-1 domain-containing 7A, prevalence, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049

Access URL: https://doaj.org/article/3f84f01eb87540bca83fc2eba96467a9

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma

Authors: Haifeng Shu, Isabel Parada, Alex Delgado, David A. Prince, Feng Gu

Source: Neurobiology of Disease, Vol 200, Iss , Pp 106634- (2024)

Subject Terms: Thrombospondin, Excitatory synapses, Epilepsy, Cortical injury, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996124002341; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/abc2e06fc6c64d05973e1fe8f9eec706

Suppressing SPARC gene with siRNA exerts therapeutic effects and inhibits MMP-2/9 and ADAMTS1 overexpression in a murine model of ischemia/reperfusion-induced acute kidney injury

Authors: Toba, Hiroe ^{a, b, ⁎}, Jin, Denan ^b, Takai, Shinji ^b

Source: In Journal of Pharmacological Sciences June 2025 158(2):103-112

Thrombospondin 2, matrix Gla protein and digital analysis identified distinct fibroblast populations in fibrostenosing Crohn’s disease

Authors: Miha Jerala, Tinkara Remic, Nina Hauptman, Pia Homan, Neža Zajšek, Mathieu Petitjean, Li Chen, Nina Zidar

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Subject Terms: Crohn’s diseases, Fibrostenosis, Myofibroblasts, Thrombospondin 2, Matrix Gla protein, Digital analysis, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e066cc313d5640759554a456dccfa917

Adipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus

Authors: Huaping Li, Hao Yang, Jingyan Liu, Hedi Yang, Xinyu Gao, Xiaoying Yang, Zhou Liu, Qiaohui Qian

Source: Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-16 (2024)

Subject Terms: Adipose-derived stem cells, Gestational diabetes mellitus, Insulin resistance, Small extracellular vesicles, Thrombospondin 1, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1758-5996

Access URL: https://doaj.org/article/a68e1ca574454a18b25ca3241b30f0a4

Potential Modulatory Role of Phoenixin-14 in Epithelial–Mesenchymal Transition of Endometriotic 12Z Cells

Authors: Karolina Iwona Kulinska, Magdalena Wierzbicka, Anna Dera-Szymanowska, Krzysztof Szymanowski, Mirosław Andrusiewicz, Maria Wołuń-Cholewa

Source: Biomedicines, Vol 13, Iss 1, p 158 (2025)

Subject Terms: endometriosis, 12Z human ectopic epithelial cell line, phoenixin-14 (PNX-14), epithelial cadherin (E-cadherin/CDH1), thrombospondin 2 (THBS2), Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/13/1/158; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/330752bc34ae4ac28ee51867927ac5a8

Thrombospondin 2 is a tumor stemness protein marker based on the cluster analysis combined with immune infiltration in gastric cancer

Authors: Wen, Jianfei ^{a, 1}, Yang, Junrong ^{b, 1}, Jiang, Lihua ^c, Ye, Wei ^c, Huang, Wen ^{c, ⁎}, Liang, Guodong ^{d, ⁎}

Source: In International Journal of Biological Macromolecules November 2024 280 Part 4

Research progress on the role of thrombospondin 2 in malignant tumors

Authors: MA Jiajunyan, RUI Tiannan, ZHANG Yongsheng

Source: Jichu yixue yu linchuang, Vol 43, Iss 12, Pp 1881-1885 (2023)

Subject Terms: thrombospondin, thrombospondin 2, carcinoma, Medicine

File Description: electronic resource

Relation: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-12-1881.pdf; https://doaj.org/toc/1001-6325

Access URL: https://doaj.org/article/b59bb725c33d4375bc0c6c95c99eb061

Single‐Cell Spatial Transcriptomics Unveils Platelet‐Fueled Cycling Macrophages for Kidney Fibrosis

Authors: Jun Liu, Bo Zheng, Qingya Cui, Yu Zhu, Likai Chu, Zhi Geng, Yiming Mao, Lin Wan, Xu Cao, Qianwei Xiong, Fujia Guo, David C Yang, Ssu‐Wei Hsu, Ching‐Hsien Chen, Xiangming Yan

Source: Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)

Subject Terms: kidney fibrosis, macrophage proliferation, platelet, thrombospondin 1, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/169b9221f5c349fc9c0bccd85efae23c

Thrombospondin 1 enhances systemic inflammation and disease severity in acute-on-chronic liver failure

Authors: Hozeifa Mohamed Hassan, Xi Liang, Jiaojiao Xin, Yingyan Lu, Qun Cai, Dongyan Shi, Keke Ren, Jun Li, Qi Chen, Jiang Li, Peng Li, Beibei Guo, Hui Yang, Jinjin Luo, Heng Yao, Xingping Zhou, Wen Hu, Jing Jiang

Source: BMC Medicine, Vol 22, Iss 1, Pp 1-17 (2024)

Subject Terms: Acute-on-chronic liver failure, Thrombospondin 1, Immune-metabolism disorder, Severity prediction, Inflammatory response, Hepatocellular apoptosis, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/0ff396ac72ca4cccbfd97b76af1b8bc4

Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration

Authors: Jing-Yu Ding, Xu Yan, Ren-Jie Zhang, Hua-Qing Zhang, Liang Kang, Chong-Yu Jia, Rick F. Thorne, Xiao-Ying Liu, Cai-Liang Shen

Source: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-15 (2024)

Subject Terms: Intervertebral disc degeneration (IVDD), Cartilage oligomeric matrix protein (COMP), A disintegrin and metalloproteinases with thrombospondin motifs7 (ADAMTS7), Biomarkers, Early diagnosis, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/c0ec04a1217e41b8824ec273ffb7ff02

Evaluation of Proclarix in the diagnostic work‐up of prostate cancer

Authors: Basil Kaufmann, Sharon Fischer, Alcibiade Athanasiou, Noémie Lautenbach, Anja Wittig, Uwe Bieri, Florian A. Schmid, Franz vonStauffenberg, Thomas Scherer, Daniel Eberli, Michael A. Gorin, Ralph Schiess, Cédric Poyet

Source: BJUI Compass, Vol 5, Iss 2, Pp 297-303 (2024)

Subject Terms: biomarkers, biopsy, cathepsin D, CTSD, Proclarix, prostate cancer, thrombospondin 1, THBS1, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/2688-4526

Access URL: https://doaj.org/article/9c1e452d1b7841658ef06caf1736ff8a

Involvement of Metalloproteases in the Fertilization of the Ascidian Halocynthia roretzi

Authors: Hitoshi Sawada, Ikuya Hattori, Noritaka Hashii, Takako Saito

Source: Biomolecules, Vol 14, Iss 12, p 1487 (2024)

Subject Terms: ascidian, fertilization, metalloprotease, astacin, protease, thrombospondin, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/12/1487; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/e1f32f4d3f074ab49a3b72ea666770fa

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

Authors: Vanhoutte, Davy ¹, Schips, Tobias G. ^{1, 3}, Minerath, Rachel A. ¹, Huo, Jiuzhou ¹, Kavuri, Naga Swathi Sree ¹, Prasad, Vikram ¹, Lin, Suh-Chin ¹, Bround, Michael J. ¹, Sargent, Michelle A. ¹, Adams, Christopher M. ², Molkentin, Jeffery D. ^{1, 4, ∗}

Source: In Cell Reports 28 May 2024 43(5)