Unusual impurity formation during the process development of Olsalazine sodium leads to a new efficient and economical synthesis of tricaine mesylate

Authors: Chaskar, Sudhir P., Honparkhe, Ramchandra, Chavan, Jagdish, Dhumal, Amit, Tripathy, Narendra K., Pramanik, Chinmoy, Chaudhari, Ashok, Thorat, Rakesh G., Gurjar, Mukund K.

Source: Journal of heterocyclic chemistry. 60(8):1464-1473

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189973092.0x000001&indx=1&recIds=ETOCvdc_100189973092.0x000001

Synthesis, Isolation and Characterization of Nine Pharmacopeial Impurities Related to the Active Pharmaceutical Ingredient Olsalazine Sodium.

Authors: Chavan, Jagdish, Chaskar, Sudhir, Vedpathak, Hanmant, Suryawanshi, Venkat, Thorat, Rakesh G., Chaudhari, Ashok, Pramanik, Chinmoy, Roychowdhury, Abhijit

Source: Synthesis; Dec2024, Vol. 56 Issue 23, p3660-3668, 9p

Subject Terms: ULCERATIVE colitis, ANTI-inflammatory agents, DIAZOTIZATION, QUALITY standards, SODIUM

Stereoselective synthesis of the C14[sbnd]C23 fragment of biselyngbyolide A and B enabled by transition metal catalysis

Authors: Thorat, Rakesh G., Brooks, Bailey A., Nichols, Brandon, Harned, Andrew M.

Source: In Tetrahedron 20 December 2018 74(51):7277-7281

An Alternative Formal Synthesis of (S)-(+)-Vigabatrin.

Authors: Chaskar, Sudhir P., Honparkhe, Ramchandra, Aghao, Arvind K., Thorat, Rakesh G., Pramanik, Chinmoy

Source: Synthesis; Feb2024, Vol. 56 Issue 4, p549-552, 4p

Subject Terms: VINYL polymers, SEIZURES (Medicine), RING formation (Chemistry), CATALYTIC hydrogenation, ACETIC acid, MANUFACTURING processes

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ChemInform Abstract: Enantioselective Synthesis of Functionalized Quaternary Stereocenters.

Authors: Manchoju, Amarender¹, Thorat, Rakesh G.¹, Pansare, Sunil V.¹

Source: ChemInform. Jan2016, Vol. 47 Issue 5, pno-no. 1p.

Subject Terms: *PRINS reaction, *ENANTIOSELECTIVE catalysis, *KINETIC resolution, *COUPLING reactions (Chemistry), *SUBSTITUTION reactions, *CHEMICAL reactions

ChemInform Abstract: Recent Advances in the Synthesis of Selected Indolizidine and Quinolizidine Alkaloids.

Authors: Pansare, Sunil V.¹, Thorat, Rakesh G.¹

Source: ChemInform. Nov2014, Vol. 45 Issue 46, pno-no. 1p.

Subject Terms: *INDOLIZIDINES synthesis, *QUINOLIZIDINE alkaloids

People: PANSARE, S. V.

ChemInform Abstract: A General Approach to 1-Hydroxymethylquinolizidine and 8-Hydroxymethylindolizidine Stereoisomers: Synthesis of (+)-Epitashiromine (I) and Formal Syntheses of (+)-Epilupinine (II) and (+)-Tashiromine (III).

Authors: Thorat, Rakesh G.¹, Pansare, Sunil V.¹

Source: ChemInform. Apr2014, Vol. 45 Issue 16, pno-no. 1p.

Subject Terms: *ALKALOID synthesis, *STEREOISOMERS