Global loss of cellular m^6A RNA methylation following infection with different SARS-CoV-2 variants

Authors: Vaid, Roshan, Mendez, Akram, Thombare, Ketan, Burgos-Panadero, Rebeca, Robinot, Rémy, Fonseca, Barbara F., Gandasi, Nikhil R., Ringlander, Johan, Baig, Mohammad Hassan, Dong, Jae-June

Source: Genome research. 33(3):299-313

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631862559&indx=1&recIds=ETOCRN631862559

Telomere Maintenance Mechanisms in a Cohort of High-Risk Neuroblastoma Tumors and Its Relation to Genomic Variants in the TERT and ATRX Genes.

Authors: Djos, Anna¹ (AUTHOR) anna.djos@gu.se, Thombare, Ketan¹ (AUTHOR) ketan.thombare@gu.se, Vaid, Roshan¹ (AUTHOR) roshan.vaid@medkem.gu.se, Gaarder, Jennie^1,2 (AUTHOR) jennie.gaarder@gu.se, Umapathy, Ganesh¹ (AUTHOR) ganesh.umapathy@gu.se, Reinsbach, Susanne E.³ (AUTHOR) susanne.reinsbach@scilifelab.se, Georgantzi, Kleopatra⁴ (AUTHOR) kleopatra.georgantzi@regionstockholm.se, Stenman, Jakob⁴ (AUTHOR) jakob.stenman@regionstockholm.se, Carén, Helena⁵ (AUTHOR) helena.caren@gu.se, Ek, Torben⁶ (AUTHOR) torben.ek@vgregion.se, Mondal, Tanmoy^1,7 (AUTHOR) tanmoy.mondal@medkem.gu.se, Kogner, Per⁴ (AUTHOR) per.kogner@ki.se, Martinsson, Tommy¹ (AUTHOR) tommy.martinsson@gu.se, Fransson, Susanne^1,2 (AUTHOR) susanne.fransson@clingen.gu.se

Source: Cancers. Dec2023, Vol. 15 Issue 24, p5732. 19p.

Subject Terms: *TELOMERES, *TISSUE arrays, *BIOMARKERS, *NEUROBLASTOMA, *GENE expression, *METHYLATION, *GENOMICS, *RESEARCH funding, *CHILDREN

METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma.

Authors: Thombare, Ketan^1,2 (AUTHOR), Vaid, Roshan^1,2 (AUTHOR), Pucci, Perla³ (AUTHOR), Ihrmark Lundberg, Kristina⁴ (AUTHOR), Ayyalusamy, Ritish^1,2 (AUTHOR), Baig, Mohammad Hassan⁵ (AUTHOR), Mendez, Akram^1,2 (AUTHOR), Burgos-Panadero, Rebeca^1,2 (AUTHOR), Höppner, Stefanie^6,7,8 (AUTHOR), Bartenhagen, Christoph^6,7,8 (AUTHOR), Sjövall, Daniel⁹ (AUTHOR), Rehan, Aqsa Ali^1,2 (AUTHOR), Dattatraya Nale, Sagar¹⁰ (AUTHOR), Djos, Anna¹ (AUTHOR), Martinsson, Tommy¹ (AUTHOR), Jaako, Pekka⁹ (AUTHOR), Dong, Jae-June⁵ (AUTHOR), Kogner, Per⁴ (AUTHOR), Johnsen, John Inge⁴ (AUTHOR), Fischer, Matthias^6,7,8 (AUTHOR)

Source: EMBO Journal. Dec2024, Vol. 43 Issue 24, p6310-6335. 26p.

Subject Terms: *HOMEOBOX genes, *GENE expression, *MEDICAL sciences, *GENETIC regulation, *NEURAL crest

Direct effects of glucagon on glucose uptake and lipolysis in human adipocytes

Authors: Pereira, Maria J., Thombare, Ketan, Sarsenbayeva, Assel, Kamble, Prasad G., Almby, Kristina, Lundqvist, Martin, Eriksson, Jan W.

Source: In Molecular and Cellular Endocrinology 1 March 2020 503

Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism

Authors: Sarsenbayeva, Assel, Marques-Santos, Cátia M., Thombare, Ketan, Di Nunzio, Giada, Almby, Kristina E., Lundqvist, Martin, Eriksson, Jan W., Pereira, Maria J.

Source: In Psychoneuroendocrinology December 2019 110

Oleate increase neutral lipid accumulation, cellular respiration and rescues palmitate-exposed GLP-1 secreting cells by reducing ceramide-induced ROS

Authors: Ntika, Stelia, Thombare, Ketan, Aryapoor, Masood, Kristinsson, Hjalti, Bergsten, Peter, Krizhanovskii, Camilla

Source: In Biochimie April 2019 159:23-35

METTL3 drives telomere targeting of TERRA lncRNA through m⁶A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma.

Authors: Vaid, Roshan, Thombare, Ketan, Mendez, Akram, Burgos-Panadero, Rebeca, Djos, Anna, Jachimowicz, Daniel, Lundberg, Kristina Ihrmark, Bartenhagen, Christoph, Kumar, Navinder, Tümmler, Conny, Sihlbom, Carina, Fransson, Susanne, Johnsen, John Inge, Kogner, Per, Martinsson, Tommy, Fischer, Matthias, Mondal, Tanmoy

Source: Nucleic Acids Research; 3/21/2024, Vol. 52 Issue 5, p2648-2671, 24p

Identifying novel inhibitors targeting Exportin-1 for the potential treatment of COVID-19.

Authors: Sharma, Tanuj, Mondal, Tanmoy, Khan, Sajid, Churqui, Marianela Patzi, Nyström, Kristina, Thombare, Ketan, Baig, Mohammad Hassan, Dong, Jae-June

Source: Archives of Microbiology; Feb2024, Vol. 206 Issue 2, p1-11, 11p

Long chain saturated and unsaturated fatty acids exert opposing effects on viability and function of GLP-1-producing cells: Mechanisms of lipotoxicity.

Authors: Thombare, Ketan¹, Ntika, Stelia¹, Wang, Xuan¹, Krizhanovskii, Camilla^1,2,3 camilla.krizhanovskii@sll.se

Source: PLoS ONE. 5/16/2017, Vol. 12 Issue 5, p1-14. 14p.

Subject Terms: *ACIDOLYSIS, *CARBOXYLIC acids, *NEUTRALIZATION (Chemistry), *APOPTOSIS, *CERAMIDES

Effects of GLP-1 on counter-regulatory responses during hypoglycemia after GBP surgery.

Authors: Almby, Kristina E., Abrahamsson, Niclas, Lundqvist, Martin H., Hammar, Ulf, Thombare, Ketan, Panagiotou, Amalia, Karlsson, F. Anders, Sundbom, Magnus, Wiklund, Urban, Eriksson, Jan W.

Source: European Journal of Endocrinology; Aug2019, Vol. 181 Issue 2, p161-171, 11p

Subject Terms: HEART beat, HYPOGLYCEMIA, GASTRIC bypass, GLUCOSE clamp technique, GLUCAGON-like peptide-1 agonists

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The Obesity-Linked Gene Nudt3 DrosophilaHomolog ApsIs Associated With Insulin Signaling

Authors: Williams, Michael J., Eriksson, Anders, Shaik, Muksheed, Voisin, Sarah, Yamskova, Olga, Paulsson, Johan, Thombare, Ketan, Fredriksson, Robert, Schiöth, Helgi B.

Source: Molecular Endocrinology; September 2015, Vol. 29 Issue: 9 p1303-1319, 17p