NCS1 overexpression restored mitochondrial activity and behavioral alterations in a zebrafish model of Wolfram syndrome

Authors: Lucie Crouzier, Elodie M. Richard, Camille Diez, Morgane Denus, Amandine Peyrel, Hala Alzaeem, Nicolas Cubedo, Thomas Delaunay, Tangui Maurice, Benjamin Delprat

Source: Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 295-308 (2022)

Subject Terms: Wolfram syndrome, endoplasmic reticulum stress, mitochondria, zebrafish larvae, NCS1, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122001450; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/8a0f00345eee450bbc8aff2f87918237

Loss of Pde6a Induces Rod Outer Segment Shrinkage and Visual Alterations in pde6aQ70X Mutant Zebrafish, a Relevant Model of Retinal Dystrophy

Authors: Lucie Crouzier, Camille Diez, Elodie M. Richard, Nicolas Cubedo, Clément Barbereau, Mireille Rossel, Thomas Delaunay, Tangui Maurice, Benjamin Delprat

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: PDE6A, retinitis pigmentosa, photoreceptors, rods, cones, zebrafish, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.675517/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/0a863bc44c4545b5addacfae15ecf40d