MINCLE and TLR9 agonists synergize to induce Th1/Th17 vaccine memory and mucosal recall in mice and non-human primates

Authors: Joshua S. Woodworth, Vanessa Contreras, Dennis Christensen, Thibaut Naninck, Nidhal Kahlaoui, Anne-Sophie Gallouët, Sébastien Langlois, Emma Burban, Candie Joly, Wesley Gros, Nathalie Dereuddre-Bosquet, Julie Morin, Ming Liu Olsen, Ida Rosenkrands, Ann-Kathrin Stein, Grith Krøyer Wood, Frank Follmann, Thomas Lindenstrøm, Tu Hu, Roger Le Grand, Gabriel Kristian Pedersen, Rasmus Mortensen

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/247707a325064a6ea6e1237d4d196721

Improved Automated Radiosynthesis of [18F]Dolutegravir: Toward Clinical Applications

Authors: Steve Huvelle, Antoine Pinon, Christine Coulon, Thomas Bonasera, Catherine Chapon, Thibaut Naninck, Roger Le Grand, Chris M. Parry, Bertrand Kuhnast, Fabien Caillé

Source: ACS Omega, Vol 9, Iss 40, Pp 41732-41741 (2024)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/19496fc1ee754918bc9b9e3a2670b273

Immunogenicity and efficacy of VLA2001 vaccine against SARS-CoV-2 infection in male cynomolgus macaques

Authors: Mathilde Galhaut, Urban Lundberg, Romain Marlin, Robert Schlegl, Stefan Seidel, Ursula Bartuschka, Jürgen Heindl-Wruss, Francis Relouzat, Sébastien Langlois, Nathalie Dereuddre-Bosquet, Julie Morin, Maxence Galpin-Lebreau, Anne-Sophie Gallouët, Wesley Gros, Thibaut Naninck, Quentin Pascal, Catherine Chapon, Karine Mouchain, Guillaume Fichet, Julien Lemaitre, Mariangela Cavarelli, Vanessa Contreras, Nicolas Legrand, Andreas Meinke, Roger Le Grand

Source: Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2730-664X

Access URL: https://doaj.org/article/b20cf0b0a10841d78b8331ab24c32b42

Antiviral efficacy of favipiravir against Zika and SARS-CoV-2 viruses in non-human primates

Authors: Romain Marlin, Delphine Desjardins, Vanessa Contreras, Guillaume Lingas, Caroline Solas, Pierre Roques, Thibaut Naninck, Quentin Pascal, Sylvie Behillil, Pauline Maisonnasse, Julien Lemaitre, Nidhal Kahlaoui, Benoit Delache, Andrés Pizzorno, Antoine Nougairede, Camille Ludot, Olivier Terrier, Nathalie Dereuddre-Bosquet, Francis Relouzat, Catherine Chapon, Raphael Ho Tsong Fang, Sylvie van der Werf, Manuel Rosa Calatrava, Denis Malvy, Xavier de Lamballerie, Jeremie Guedj, Roger Le Grand

Source: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cee3e8b3e2194e7993477900e8552973

Impact of a PMMA tube on performances of a Vereos PET/CT system adapted for BSL-3 environment according to the NEMA NU2-2012 standard

Authors: Nidhal Kahlaoui, Thibaut Naninck, Roger Le Grand, Catherine Chapon

Source: EJNMMI Physics, Vol 9, Iss 1, Pp 1-10 (2022)

Subject Terms: PET/CT, NEMA NU2-2012 standard, BSL-3 conditions, Infectious diseases, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2197-7364

Access URL: https://doaj.org/article/bf52e1437b564360b33e8b05cb26409c

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

Authors: Pauline Maisonnasse, Yoann Aldon, Aurélien Marc, Romain Marlin, Nathalie Dereuddre-Bosquet, Natalia A. Kuzmina, Alec W. Freyn, Jonne L. Snitselaar, Antonio Gonçalves, Tom G. Caniels, Judith A. Burger, Meliawati Poniman, Ilja Bontjer, Virginie Chesnais, Ségolène Diry, Anton Iershov, Adam J. Ronk, Sonia Jangra, Raveen Rathnasinghe, Philip J. M. Brouwer, Tom P. L. Bijl, Jelle van Schooten, Mitch Brinkkemper, Hejun Liu, Meng Yuan, Chad E. Mire, Mariëlle J. van Breemen, Vanessa Contreras, Thibaut Naninck, Julien Lemaître, Nidhal Kahlaoui, Francis Relouzat, Catherine Chapon, Raphaël Ho Tsong Fang, Charlene McDanal, Mary Osei-Twum, Natalie St-Amant, Luc Gagnon, David C. Montefiori, Ian A. Wilson, Eric Ginoux, Godelieve J. de Bree, Adolfo García-Sastre, Michael Schotsaert, Lynda Coughlan, Alexander Bukreyev, Sylvie van der Werf, Jérémie Guedj, Rogier W. Sanders, Marit J. van Gils, Roger Le Grand

Source: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cb63fd675fbc4192b0ac21fa54904b08

Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

Authors: Romain Marlin, Veronique Godot, Sylvain Cardinaud, Mathilde Galhaut, Severin Coleon, Sandra Zurawski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Pauline Maisonnasse, Léa Dupaty, Craig Fenwick, Thibaut Naninck, Julien Lemaitre, Mario Gomez-Pacheco, Nidhal Kahlaoui, Vanessa Contreras, Francis Relouzat, Raphaël Ho Tsong Fang, Zhiqing Wang, Jerome Ellis, Catherine Chapon, Mireille Centlivre, Aurelie Wiedemann, Christine Lacabaratz, Mathieu Surenaud, Inga Szurgot, Peter Liljeström, Delphine Planas, Timothée Bruel, Olivier Schwartz, Sylvie van der Werf, Giuseppe Pantaleo, Mélanie Prague, Rodolphe Thiébaut, Gerard Zurawski, Yves Lévy, Roger Le Grand

Source: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/70f82fe99a894f91b058c7b831c415e2

Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

Authors: Marie Alexandre, Romain Marlin, Mélanie Prague, Severin Coleon, Nidhal Kahlaoui, Sylvain Cardinaud, Thibaut Naninck, Benoit Delache, Mathieu Surenaud, Mathilde Galhaut, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Pauline Maisonnasse, Mireille Centlivre, Christine Lacabaratz, Aurelie Wiedemann, Sandra Zurawski, Gerard Zurawski, Olivier Schwartz, Rogier W Sanders, Roger Le Grand, Yves Levy, Rodolphe Thiébaut

Source: eLife, Vol 11 (2022)

Subject Terms: SARS-CoV-2, correlate of protection, neutralization, vaccines, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/75427; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/648f7ac3f7ad42fca310e51f2cbaef76

A Case Study to Dissect Immunity to SARS-CoV-2 in a Neonate Nonhuman Primate Model

Authors: Claire-Maëlle Fovet, Camille Pimienta, Mathilde Galhaut, Francis Relouzat, Natalia Nunez, Mariangela Cavarelli, Quentin Sconosciuti, Nina Dhooge, Ilaria Marzinotto, Vito Lampasona, Monica Tolazzi, Gabriella Scarlatti, Raphaël Ho Tsong Fang, Thibaut Naninck, Nathalie Dereuddre-Bosquet, Jérôme Van Wassenhove, Anne-Sophie Gallouët, Pauline Maisonnasse, Roger Le Grand, Elisabeth Menu, Nabila Seddiki

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: SARS-CoV-2, innate immunity, type-I IFN, pediatric, neonate, children, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.855230/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/6503d2321a1a4759a73aa2e01cd514e5

Computed tomography and [18F]-FDG PET imaging provide additional readouts for COVID-19 pathogenesis and therapies evaluation in non-human primates

Authors: Thibaut Naninck, Nidhal Kahlaoui, Julien Lemaitre, Pauline Maisonnasse, Antoine De Mori, Quentin Pascal, Vanessa Contreras, Romain Marlin, Francis Relouzat, Benoît Delache, Cécile Hérate, Yoann Aldon, Marit van Gils, Nerea Zabaleta, Raphaël Ho Tsong Fang, Nathalie Bosquet, Rogier W. Sanders, Luk H. Vandenberghe, Catherine Chapon, Roger Le Grand

Source: iScience, Vol 25, Iss 4, Pp 104101- (2022)

Subject Terms: Medical microbiology, Medical imaging, Virology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222003716; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/f12f03d30c0a4e47bd9abf390fbc8fec

Intranasal inoculation with Bordetella pertussis confers protection without inducing classical whooping cough in baboons

Authors: Thibaut Naninck, Vanessa Contreras, Loïc Coutte, Sébastien Langlois, Aurélie Hébert-Ribon, Magali Pelletier, Nathalie Reveneau, Camille Locht, Catherine Chapon, Roger Le Grand

Source: Current Research in Microbial Sciences, Vol 2, Iss , Pp 100072- (2021)

Subject Terms: Whooping cough, Pertussis, Non-human primates, Baboons, Microbiology, QR1-502, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666517421000535; https://doaj.org/toc/2666-5174

Access URL: https://doaj.org/article/b7675aea59744d498db80e2bcd7515a6

SARS-CoV-2 viral dynamics in non-human primates.

Authors: Antonio Gonçalves, Pauline Maisonnasse, Flora Donati, Mélanie Albert, Sylvie Behillil, Vanessa Contreras, Thibaut Naninck, Romain Marlin, Caroline Solas, Andres Pizzorno, Julien Lemaitre, Nidhal Kahlaoui, Olivier Terrier, Raphael Ho Tsong Fang, Vincent Enouf, Nathalie Dereuddre-Bosquet, Angela Brisebarre, Franck Touret, Catherine Chapon, Bruno Hoen, Bruno Lina, Manuel Rosa Calatrava, Xavier de Lamballerie, France Mentré, Roger Le Grand, Sylvie van der Werf, Jérémie Guedj

Source: PLoS Computational Biology, Vol 17, Iss 3, p e1008785 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008785&type=printable; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/0fa0b9d2f5e5421e8a4721a215607b84