Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials

Authors: Vincent Madelain, France Mentré, Sylvain Baize, Xavier Anglaret, Cédric Laouénan, Lisa Oestereich, Thi Huyen Tram Nguyen, Denis Malvy, Géraldine Piorkowski, Frederik Graw, Stephan Günther, Hervé Raoul, Xavier deLamballerie, Jérémie Guedj

Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 5, Pp 258-271 (2020)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2163-8306

Access URL: https://doaj.org/article/c3eb6c0c096749a2a43547dd624cdc4d

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques.

Authors: Jérémie Guedj, Géraldine Piorkowski, Frédéric Jacquot, Vincent Madelain, Thi Huyen Tram Nguyen, Anne Rodallec, Stephan Gunther, Caroline Carbonnelle, France Mentré, Hervé Raoul, Xavier de Lamballerie

Source: PLoS Medicine, Vol 15, Iss 3, p e1002535 (2018)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/147194498faa4e8586598c051a408aa6

Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted.

Authors: Thi Huyen Tram Nguyen, Jérémie Guedj, Xavier Anglaret, Cédric Laouénan, Vincent Madelain, Anne-Marie Taburet, Sylvain Baize, Daouda Sissoko, Boris Pastorino, Anne Rodallec, Géraldine Piorkowski, Sara Carazo, Mamoudou N Conde, Jean-Luc Gala, Joseph Akoi Bore, Caroline Carbonnelle, Frédéric Jacquot, Hervé Raoul, Denis Malvy, Xavier de Lamballerie, France Mentré, JIKI study group

Source: PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005389 (2017)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5340401?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/7f6efdf3b05345baa7f586719e1ce176

Persistence and clearance of Ebola virus RNA from seminal fluid of Ebola virus disease survivors: a longitudinal analysis and modelling study

Authors: Daouda Sissoko, MD, Sophie Duraffour, PhD, Romy Kerber, PhD, Jacques Seraphin Kolie, MD, Abdoul Habib Beavogui, PhD, Alseny-Modet Camara, MD, Géraldine Colin, PharmD, Toni Rieger, PhD, Lisa Oestereich, PhD, Bernadett Pályi, MSc, Stephanie Wurr, Jeremie Guedj, PhD, Thi Huyen Tram Nguyen, PhD, Rosalind M Eggo, PhD, Conall H Watson, MFPH, W John Edmunds, PhD, Joseph Akoi Bore, MSc, Fara Raymond Koundouno, MSc, Mar Cabeza-Cabrerizo, MSc, Lisa L Carter, PhD, Liana Eleni Kafetzopoulou, MSc, Eeva Kuisma, PhD, Janine Michel, PhD, Livia Victoria Patrono, PhD, Natasha Y Rickett, MRes, Katrin Singethan, PhD, Martin Rudolf, PhD, Angelika Lander, Elisa Pallasch, Sabrina Bockholt, Estefanía Rodríguez, PhD, Antonino Di Caro, MD, Roman Wölfel, MD, Martin Gabriel, MD, Céline Gurry, Pierre Formenty, DVM, Sakoba Keïta, MD, Denis Malvy, PhD, Miles W Carroll, PhD, Xavier Anglaret, PhD, Stephan Günther, DrMD

Source: The Lancet Global Health, Vol 5, Iss 1, Pp e80-e88 (2017)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214109X16302431; https://doaj.org/toc/2214-109X

Access URL: https://doaj.org/article/314da369604a4f28aa4a36804e6d024f

Improvement of ALT decay kinetics by all-oral HCV treatment: Role of NS5A inhibitors and differences with IFN-based regimens.

Authors: Valeria Cento, Thi Huyen Tram Nguyen, Domenico Di Carlo, Elisa Biliotti, Laura Gianserra, Ilaria Lenci, Daniele Di Paolo, Vincenza Calvaruso, Elisabetta Teti, Maddalena Cerrone, Dante Romagnoli, Michela Melis, Elena Danieli, Barbara Menzaghi, Ennio Polilli, Massimo Siciliano, Laura Ambra Nicolini, Antonio Di Biagio, Carlo Federico Magni, Matteo Bolis, Francesco Paolo Antonucci, Velia Chiara Di Maio, Roberta Alfieri, Loredana Sarmati, Paolo Casalino, Sergio Bernardini, Valeria Micheli, Giuliano Rizzardini, Giustino Parruti, Tiziana Quirino, Massimo Puoti, Sergio Babudieri, Antonella D'Arminio Monforte, Massimo Andreoni, Antonio Craxì, Mario Angelico, Caterina Pasquazzi, Gloria Taliani, Jeremie Guedj, Carlo Federico Perno, Francesca Ceccherini-Silberstein

Source: PLoS ONE, Vol 12, Iss 5, p e0177352 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5436665?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/22236f0345a647d8a5230cf0f10d43c0

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