Piezo2 Is a Key Mechanoreceptor in Lung Fibrosis that Drives Myofibroblast Differentiation

Authors: Freeberg, Margaret A.T. ^∗, Camus, Sarah V. ^∗, Robila, Valentina ^†, Perelas, Apostolos ^∗, Thatcher, Thomas H. ^∗, Sime, Patricia J. ^{∗, ∗}

Source: In The American Journal of Pathology April 2025 195(4):626-638

Is there a role for specialized pro-resolving mediators in pulmonary fibrosis?

Authors: Thatcher, Thomas H., Freeberg, Margaret A.T., Myo, Yu Par Aung, Sime, Patricia J.

Source: In Pharmacology and Therapeutics July 2023 247

Dung biomass smoke exposure impairs resolution of inflammatory responses to influenza infection

Authors: McCarthy, Claire E., Duffney, Parker F., Nogales, Aitor, Post, Christina M., Lawrence, B. Paige, Martinez-Sobrido, Luis, Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.

Source: In Toxicology and Applied Pharmacology 1 September 2022 450

Specialized pro-resolving mediators as modulators of immune responses

Authors: Julliard, Walker A., Myo, Yu Par Aung, Perelas, Apostolos, Jackson, Peter D., Thatcher, Thomas H., Sime, Patricia J.

Source: In Seminars in Immunology January 2022 59

Mechanical Feed-Forward Loops Contribute to Idiopathic Pulmonary Fibrosis

Authors: Freeberg, Margaret A.T., Perelas, Apostolos, Rebman, Jane K., Phipps, Richard P., Thatcher, Thomas H., Sime, Patricia J.

Source: In The American Journal of Pathology January 2021 191(1):18-25

Analysis of Postdeployment Serum Samples Identifies Potential Biomarkers of Exposure to Burn Pits and Other Environmental Hazards

Authors: Thatcher, Thomas H., Woeller, Collynn F., Thakar, Juilee, Khan, Atif, Hopke, Philip K., Smith, Matthew Ryan, Uppal, Karan, Walker, Douglas I., Go, Young-Mi, Jones, Dean P., Krahl, Pamela L., Mallon, Timothy M., Sime, Patricia J., Phipps, Richard P., Utell, Mark J.

Source: Journal of Occupational and Environmental Medicine, 2019 Dec 01. 61(12S), S45-S54.

Access URL: https://www.jstor.org/stable/48559564

Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Variations in Service Personnel Deployed to Balad and Bagram

Authors: Thakar, Juilee, Thatcher, Thomas H., Smith, Matthew Ryan, Woeller, Collynn F., Walker, Douglas I., Utell, Mark J., Hopke, Philip K., Mallon, Timothy M., Krahl, Pamela L., Rohrbeck, Patricia, Go, Young-Mi, Jones, Dean P., Uppal, Karan

Source: Journal of Occupational and Environmental Medicine, 2019 Dec 01. 61(12S), S65-S72.

Access URL: https://www.jstor.org/stable/48559566

Exposure to Heptachlorodibenzo-p-dioxin (HpCDD) Regulates microRNA Expression in Human Lung Fibroblasts

Authors: Woeller, Collynn F., Thatcher, Thomas H., Thakar, Juilee, Cornwell, Adam, Smith, Matthew R., Jones, Dean P., Hopke, Philip K., Sime, Patricia J., Krahl, Pamela, Mallon, Timothy M., Phipps, Richard P., Utell, Mark J.

Source: Journal of Occupational and Environmental Medicine, 2019 Dec 01. 61(12S), S82-S89.

Access URL: https://www.jstor.org/stable/48559568

Advances in Comprehensive Exposure Assessment : Opportunities for the US Military

Authors: Krahl, Pamela L., Benchoff, Edward, Go, Young-Mi, Jones, Dean P., Smith, Matthew Ryan, Walker, Douglas I., Uppal, Karan, Woeller, Collynn F., Thatcher, Thomas H., Thakar, Juilee, Phipps, Richard P., Hopke, Philip, Utell, Mark J., Mallon, Timothy M.

Source: Journal of Occupational and Environmental Medicine, 2019 Dec 01. 61(12S), S5-S14.

Access URL: https://www.jstor.org/stable/48559560

Machine Learning Approach for Predicting Past Environmental Exposures From Molecular Profiling of Post-Exposure Human Serum Samples

Authors: Khan, Atif, Thatcher, Thomas H., Woeller, Collynn F., Sime, Patricia J., Phipps, Richard P., Hopke, Philip K., Utell, Mark J., Krahl, Pamela L., Mallon, Timothy M., Thakar, Juilee

Source: Journal of Occupational and Environmental Medicine, 2019 Dec 01. 61(12S), S55-S64.

Access URL: https://www.jstor.org/stable/48559565

Associations of Benzo(ghi)perylene and Heptachlorodibenzo-p-dioxin in Serum of Service Personnel Deployed to Balad, Iraq, and Bagram, Afghanistan Correlates With Perturbed Amino Acid Metabolism in Human Lung Fibroblasts

Authors: Smith, Matthew Ryan, Woeller, Collynn F., Uppal, Karan, Thatcher, Thomas H., Walker, Douglas I., Hopke, Philip K., Rohrbeck, Patricia, Mallon, Timothy M., Krahl, Pamela L., Utell, Mark J., Go, Young-Mi, Jones, Dean P.

Source: Journal of Occupational and Environmental Medicine, 2019 Dec 01. 61(12S), S35-S44.

Access URL: https://www.jstor.org/stable/48559563

Use of Biomarkers to Assess Environmental Exposures and Health Outcomes in Deployed Troops

Authors: Mallon, Timothy M., Krahl, Pamela K., Haines, Kevin M., Walker, Douglas I., Thatcher, Thomas, Woeller, Collynn F., Thakar, Juilee, Hopke, Philip K., Gaydos, Joel C., Smith, Mathew Ryan, Uppal, Karan, Go, Young-Mi, Jones, Dean P., Utell, Mark

Source: Journal of Occupational and Environmental Medicine, 2019 Dec 01. 61(12S), S1-S4.

Access URL: https://www.jstor.org/stable/48559559

Quenching the fires: Pro-resolving mediators, air pollution, and smoking

Authors: Thatcher, Thomas H., Woeller, Collynn F., McCarthy, Claire E., Sime, Patricia J.

Source: In Pharmacology and Therapeutics May 2019 197:212-224

The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis

Authors: Judge, Jennifer L., Lacy, Shannon H., Ku, Wei-Yao, Owens, Kristina M., Hernady, Eric, Thatcher, Thomas H., Williams, Jacqueline P., Phipps, Richard P., Sime, Patricia J., Kottmann, R. Matthew

Source: Radiation Research, 2017 Jul 01. 188(1), 35-43.

Access URL: https://www.jstor.org/stable/26428248

Comparison of in vitro toxicological effects of biomass smoke from different sources of animal dung

Authors: McCarthy, Claire E., Duffney, Parker F., Wyatt, Jeffrey D., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.

Source: In Toxicology in Vitro September 2017 43:76-86

Transglutaminase 2 knockout mice are protected from bleomycin‐induced lung fibrosis with preserved lung function and reduced metabolic derangements.

Authors: Freeberg, Margaret A. T.^1,2 (AUTHOR), Thatcher, Thomas H.^1,2 (AUTHOR), Camus, Sarah V.¹ (AUTHOR), Huang, Linghong³ (AUTHOR), Atkinson, John³ (AUTHOR), Narrow, Wade² (AUTHOR), Haak, Jeannie⁴ (AUTHOR), Dylag, Andrew M.⁴ (AUTHOR), Cowart, L. Ashley⁵ (AUTHOR), Johnson, Timothy S.³ (AUTHOR), Sime, Patricia J.^1,2 (AUTHOR) patricia.sime@vcuhealth.org

Source: Physiological Reports. Jun2024, Vol. 12 Issue 12, p1-12. 12p.

Subject Terms: *PULMONARY fibrosis, *INTERSTITIAL lung diseases, *KNOCKOUT mice, *METABOLIC reprogramming, *LACTATE dehydrogenase, *BLEOMYCIN, *GENETIC models

Introduction to Department of Defense Research on Burn Pits, Biomarkers, and Health Outcomes Related to Deployment in Iraq and Afghanistan

Authors: Mallon, Timothy M., Rohrbeck, Patricia, Haines, Kevin M., Jones, Dean P., Utell, Mark, Hopke, Philip K., Phipps, Richard P., Walker, Douglas I., Thatcher, Thomas, Woeller, Collynn F., Baird, Coleen P., Pollard, Harvey B., Dalgard, Clifton L., Gaydos, Joel C.

Source: Journal of Occupational and Environmental Medicine, 2016 Aug 01. 58(8S), S3-S11.

Access URL: https://www.jstor.org/stable/48501287

Detection of Serum microRNAs From Department of Defense Serum Repository : Correlation With Cotinine, Cytokine, and Polycyclic Aromatic Hydrocarbon Levels

Authors: Woeller, Collynn F., Thatcher, Thomas H., Van Twisk, Daniel, Pollock, Stephen J., Croasdell, Amanda, Kim, Nina, Hopke, Philip K., Xia, Xiaoyan, Thakar, Juilee, Mallon, Timothy M., Utell, Mark J., Phipps, Richard P.

Source: Journal of Occupational and Environmental Medicine, 2016 Aug 01. 58(8S), S62-S71.

Access URL: https://www.jstor.org/stable/48501294

MicroRNAs as Novel Biomarkers of Deployment Status and Exposure to Polychlorinated Dibenzo- p -Dioxins/Dibenzofurans

Authors: Woeller, Collynn F., Thatcher, Thomas H., Van Twisk, Daniel, Pollock, Stephen J., Croasdell, Amanda, Hopke, Philip K., Xia, Xiaoyan, Thakar, Juilee, Sime, Patricia J., Mallon, Timothy M., Utell, Mark J., Phipps, Richard P.

Source: Journal of Occupational and Environmental Medicine, 2016 Aug 01. 58(8S), S89-S96.

Access URL: https://www.jstor.org/stable/48501297

Resolvin D1 Reduces Emphysema and Chronic Inflammation

Authors: Hsiao, Hsi-Min, Thatcher, Thomas H., Colas, Romain A., Serhan, Charles N., Phipps, Richard P., Sime, Patricia J.

Source: In The American Journal of Pathology December 2015 185(12):3189-3201