FOXO1 promotes HIV latency by suppressing ER stress in T cells

Authors: Vallejo-Gracia, Albert, Chen, Irene P., Perrone, Rosalba, Besnard, Emilie, Boehm, Daniela, Battivelli, Emilie, Tezil, Tugsan, Krey, Karsten, Raymond, Kyle A., Hull, Philip A., Walter, Marius, Habrylo, Ireneusz, Cruz, Andrew, Deeks, Steven, Pillai, Satish, Verdin, Eric, Ott, Melanie

Source: Nature microbiology. 5(9):1144-1157

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174417491.0x000001&indx=1&recIds=ETOCvdc_100174417491.0x000001

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

Authors: Celestini, Valentina, Tezil, Tugsan, Russo, Luciana, Fasano, Candida, Sanese, Paola, Forte, Giovanna, Peserico, Alessia, Lepore Signorile, Martina, Longo, Giovanna, De Rasmo, Domenico, Signorile, Anna, Gadaleta, Raffaella, Scialpi, Natasha, Terao, Mineko, Garattini, Enrico, Cocco, Tiziana, Villani, Gaetano, Moschetta, Antonio, Grossi, Valentina, Simone, Cristiano

Source: Cell death and disease. 9(2):1-20

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112267779.0x000001&indx=1&recIds=ETOCvdc_100112267779.0x000001

Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes

Authors: Shrimp, Jonathan H., Garlick, Julie M., Tezil, Tugsan, Sorum, Alexander W., Worth, Andrew J., Blair, Ian A., Verdin, Eric, Snyder, Nathaniel W., Meier, Jordan L.

Source: Molecular pharmaceutics. 15(3):729-736

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN615152181&indx=1&recIds=ETOCRN615152181

Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A

Authors: Germani, Aldo, Matrone, Antonio, Grossi, Valentina, Peserico, Alessia, Sanese, Paola, Liuzzi, Micaela, Palermo, Rocco, Murzilli, Stefania, Campese, Antonio Francesco, Ingravallo, Giuseppe, Canettieri, Gianluca, Tezil, Tugsan, Simone, Cristiano

Source: In Cancer Letters 1 March 2014 344(1):110-118

T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin.

Authors: Lindqvist, Birgitta¹, Jütte, Bianca B.¹, Love, Luca¹, Assi, Wlaa^1,2, Roux, Julie¹, Sönnerborg, Anders³, Tezil, Tugsan⁴, Verdin, Eric⁴, Svensson, J. Peter¹, peter.svensson@ki.se

Source: PLoS Pathogens; 6/6/2022, Vol. 18 Issue 6, p1-24, 24p

IKK-β mediates chemoresistance by sequestering FOXO3; A critical factor for cell survival and death

Authors: Tezil, Tugsan, Bodur, Cagri, Kutuk, Ozgur, Basaga, Huveyda

Source: In Cellular Signalling June 2012 24(6):1361-1368

Modulation of Cell Death in Age-Related Diseases

Authors: Tezil, Tugsan, Basaga, Huveyda

Source: Current pharmaceutical design. 20(18):3052-3067

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100048274698.0x000001&indx=1&recIds=ETOCvdc_100048274698.0x000001

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Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes

Authors: Shrimp, Jonathan H., Garlick, Julie M., Tezil, Tugsan, Sorum, Alexander W., Worth, Andrew J., Blair, Ian A., Verdin, Eric, Snyder, Nathaniel W., Meier, Jordan L.

Source: Molecular Pharmaceutics; 20240101, Issue: Preprints

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Inactivation of Bcl-2 through IκB kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE).

Authors: Bodur, Cagri, Kutuk, Ozgur, Tezil, Tugsan, Basaga, Huveyda

Source: Journal of Cellular Physiology; Nov2012, Vol. 227 Issue 11, p3556-3565, 10p, 3 Black and White Photographs, 4 Graphs

Subject Terms: APOPTOSIS, BCL-2 proteins, PHOSPHORYLATION, ATHEROSCLEROTIC plaque, ALDEHYDES, HELA cells, UBIQUITINATION, PROTEOLYSIS

Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy.

Authors: Tezil, Tugsan, Chamoli, Manish, Ng, Che-Ping, Simon, Roman P., Butler, Victoria J., Jung, Manfred, Andersen, Julie, Kao, Aimee W., Verdin, Eric

Source: NPJ Aging & Mechanisms of Disease; 10/2/2019, Vol. 5 Issue 1, pN.PAG-N.PAG, 1p