Ubiquitin-specific proteases as therapeutic targets in paediatric primary bone tumours?

Authors: Mullard, Mathilde, Lavaud, Mélanie, Regnier, Laura, Tesfaye, Robel, Ory, Benjamin, Rédini, Françoise, Verrecchia, Franck

Source: In Biochemical Pharmacology December 2021 194

Chimeric protein EWS::FLI1 drives cell proliferation in Ewing Sarcoma viaaberrant expression of KCNN1/SK1 and dysregulation of calcium signaling

Authors: Dupuy, Maryne, Gueguinou, Maxime, Postec, Anaïs, Brion, Régis, Tesfaye, Robel, Mullard, Mathilde, Regnier, Laura, Amiaud, Jérôme, Hubsch, Clémence, Potier-Cartereau, Marie, Chantôme, Aurélie, Brounais-Le Royer, Bénédicte, Baud’huin, Marc, Georges, Steven, Lamoureux, François, Ory, Benjamin, Entz-Werlé, Natacha, Delattre, Olivier, Rédini, Françoise, Vandier, Christophe, Verrecchia, Franck

Source: Oncogene; January 2025, Vol. 44 Issue: 2 p79-91, 13p

Tracking Targets of Dynamic Super-Enhancers in Vitro to Better Characterize Osteoclastogenesis and to Evaluate the Effect of Diuron on the Maturation of Human Bone Cells.

Authors: Tesfaye, Robel A.^1,2,3, Lavaud, Melanie¹, Charrier, Céline¹, Brounais-Le Royer, Bénédicte¹, Cartron, Pierre-François^1,2,3,4, Verrecchia, Franck¹, Baud'huin, Marc¹, Lamoureux, François¹, Georges, Steven¹ Steven.Georges1@univ-nantes.fr, Ory, Benjamin^1,2,3 benjamin.ory@univ-nantes.fr

Source: Environmental Health Perspectives. Jun2023, Vol. 131 Issue 6, p067007-1-067007-14. 14p. 1 Color Photograph, 1 Chart, 3 Graphs.

Subject Terms: *HOMEOSTASIS, *SUPER enhancers, *IN vitro studies, *OSTEOCLASTS, *BONE growth, *SEQUENCE analysis, *BONE resorption, *CELL physiology, *RNA, *PRECIPITIN tests, *CELL survival, *GENE expression profiling, *BONE remodeling, *DESCRIPTIVE statistics, *ODDS ratio, *HEMOPROTEINS, *ALGORITHMS

BET bromodomains' functions in bone-related pathologies

Authors: Jacques, Camille, Lavaud, Melanie, Georges, Steven, Tesfaye, Robel, Baud'huin, Marc, Lamoureux, François, Ory, Benjamin

Source: Epigenomics. 12(2):127-144

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186812054.0x000001&indx=1&recIds=ETOCvdc_100186812054.0x000001

Ni-Co bimetal decorated carbon nanotube aerogel as an efficient anode catalyst in urea fuel cells

Authors: Tesfaye, Robel, Das, Gautam, Park, Bang, Kim, Jihyeon, Yoon, Hyon

Source: Scientific reports. 9(1):1-9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111633733.0x000001&indx=1&recIds=ETOCvdc_100111633733.0x000001

RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature

Authors: Le Caignec, Cedric, Ory, Benjamin, Lamoureux, François, O'Donohue, Marie-Francoise, Orgebin, Emilien, Lindenbaum, Pierre, Téletchéa, Stéphane, Saby, Manon, Hurst, Anna, Nelson, Katherine, Gilbert, Shawn R., Wilnai, Yael, Zeitlin, Leonid, Segev, Eitan, Tesfaye, Robel, Nizon, Mathilde, Cogne, Benjamin, Bezieau, Stéphane, Geoffroy, Loic, Hamel, Antoine, Mayrargue, Emmanuelle, de Courtivron, Benoît, Decock-Giraudaud, Aliette, Charrier, Céline, Pichon, Olivier, Retière, Christelle, Redon, Richard, Pepler, Alexander, McWalter, Kirsty, Da Costa, Lydie, Toutain, Annick, Gleizes, Pierre-Emmanuel, Baud'huin, Marc, Isidor, Bertrand

Source: American journal of human genetics. 105(5):1040-1047

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100092595554.0x000001&indx=1&recIds=ETOCvdc_100092595554.0x000001

NiO-Fe2O3 based graphene aerogel as urea electrooxidation catalyst

Authors: Das, Gautam, Tesfaye, Robel Mehari, Won, Yusun, Yoon, Hyon Hee

Source: In Electrochimica Acta 20 May 2017 237:171-176

Super-enhancers: drivers of cells' identities and cells' debacles.

Authors: Lavaud, Mélanie, Tesfaye, Robel, Lassous, Léa, Brounais, Bénédicte, Baud'huin, Marc, Verrecchia, Franck, Lamoureux, François, Georges, Steven, Ory, Benjamin

Source: Epigenomics; May2024, Vol. 16 Issue 9, p681-700, 20p

The p53 Family Members p63 and p73 Roles in the Metastatic Dissemination: Interactions with microRNAs and TGFβ Pathway.

Authors: Rodriguez Calleja, Lidia, Lavaud, Melanie, Tesfaye, Robel, Brounais-Le-Royer, Bénédicte, Baud'huin, Marc, Georges, Steven, Lamoureux, François, Verrecchia, Franck, Ory, Benjamin

Source: Cancers; Dec2022, Vol. 14 Issue 23, p5948, 14p

Subject Terms: TRANSFORMING growth factors-beta, HOMEOSTASIS, ONCOGENES, MICRORNA, METASTASIS, APOPTOSIS, CELL physiology, GENE expression, TUMOR suppressor genes, TRANSCRIPTION factors, DNA damage

Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis.

Authors: Morice, Sarah, Danieau, Geoffroy, Tesfaye, Robel, Mullard, Mathilde, Brion, Régis, Dupuy, Maryne, Ory, Benjamin, Brounais-Le Royer, Bénédicte, Corre, Isabelle, Redini, Françoise, Verrecchia, Franck

Source: Frontiers in Oncology; 10/26/2021, Vol. 11, p1-13, 13p

Subject Terms: CELLULAR signal transduction, EPITHELIAL-mesenchymal transition, OSTEOSARCOMA, SURVIVAL rate, LUNG development

Insights into Ir-Based Trimetallic Nano-Catalyst for Acidic Water Electrolysis.

Authors: Tesfaye, Robel Mehari, Chuang, Po-Ya Abel, Karmakar, Ayon

Source: ECS Meeting Abstracts; 2024, Vol. MA2024-01 Issue 1, p1768-1768, 1p

Implication of the p53-Related miR-34c, -125b, and -203 in the Osteoblastic Differentiation and the Malignant Transformation of Bone Sarcomas.

Authors: Jacques, Camille¹ (AUTHOR) cjacques44000@gmail.com, Tesfaye, Robel¹ (AUTHOR), Lavaud, Melanie¹ (AUTHOR), Georges, Steven¹ (AUTHOR), Baud'huin, Marc¹ (AUTHOR), Lamoureux, François¹ (AUTHOR), Ory, Benjamin¹ (AUTHOR) Benjamin.ory@univ-nantes.fr

Source: Cells (2073-4409). Apr2020, Vol. 9 Issue 4, p810. 1p.

Subject Terms: *OSTEOSARCOMA, *P53 protein, *BONE cells, *CELLULAR aging, *NON-coding RNA, *FRACTURE healing, *OSTEOCLASTS, *OSTEOBLASTS

Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619.

Authors: Lavaud, Mélanie, Mullard, Mathilde, Tesfaye, Robel, Amiaud, Jérôme, Legrand, Mélanie, Danieau, Geoffroy, Brion, Régis, Morice, Sarah, Regnier, Laura, Dupuy, Maryne, Brounais-Le Royer, Bénédicte, Lamoureux, François, Ory, Benjamin, Rédini, Françoise, Verrecchia, Franck

Source: Cells (2073-4409); Sep2021, Vol. 10 Issue 9, p2268, 1p

Subject Terms: DEUBIQUITINATING enzymes, TUMOR growth, LUNG development, CELL lines, LUNG tumors, LUNGS

The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth.

Authors: Morice, Sarah, Mullard, Mathilde, Brion, Regis, Dupuy, Maryne, Renault, Sarah, Tesfaye, Robel, Brounais-Le Royer, Bénédicte, Ory, Benjamin, Redini, Françoise, Verrecchia, Franck

Source: Cancers; Dec2020, Vol. 12 Issue 12, p3847, 1p

Subject Terms: ANIMAL experimentation, CELL lines, CELLULAR signal transduction, MICE, OSTEOSARCOMA, RNA, VERTEPORFIN, PHARMACODYNAMICS