Artemether–lumefantrine with or without single-dose primaquine and sulfadoxine–pyrimethamine plus amodiaquine with or without single-dose tafenoquine to reduce Plasmodium falciparum transmission: a phase 2, single-blind, randomised clinical trial in Ouelessebougou, Mali

Authors: Mahamar, Almahamoudou ^{a, ∗, ∗}, Smit, Merel J ^{b, ∗}, Sanogo, Koualy ^a, Sinaba, Youssouf ^a, Niambele, Sidi M ^a, Sacko, Adama ^a, Dicko, Oumar M ^a, Diallo, Makonon ^a, Maguiraga, Seydina O ^a, Sankaré, Yaya ^a, Keita, Sekouba ^a, Samake, Siaka ^a, Dembele, Adama ^a, Lanke, Kjerstin ^b, ter Heine, Rob ^c, Bradley, John ^d, Dicko, Yahia ^a, Traore, Sekou F ^a, Drakeley, Chris ^{e, ∗}, Dicko, Alassane ^{a, ∗}, Bousema, Teun ^{b, ∗}, Stone, Will ^{e, ∗}

Source: In The Lancet Microbe July 2024 5(7):633-644

Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study)

Authors: Overbeek, Joanneke K., Guchelaar, Niels A.D., Mohmaed Ali, Ma Ida, Ottevanger, Petronella B., Bloemendal, Haiko J., Koolen, Stijn L.W., Mathijssen, Ron H.J., Boere, Ingrid A., Hamberg, Paul, Huitema, Alwin D.R., Sonke, Gabe S., Opdam, Frans L., ter Heine, Rob, van Erp, Nielka P.

Source: In European Journal of Cancer November 2023 194

What the Product Label Does Not Tell You About Drug–Drug Interaction Management

Authors: Burger, David M., le Comte, Marianne, Smolders, Elise J., Jacobs, Tom G., ter Heine, Rob, Knibbe, Catherijne A.J., Pirmohamed, Munir

Source: Journal of clinical pharmacology. 63(11):1181-1185

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195613317.0x000001&indx=1&recIds=ETOCvdc_100195613317.0x000001

Individualized dosing of evinacumab is predicted to yield reductions in drug expenses

Authors: ter Heine, Rob, Rongen, Gerard A., Roeters van Lennep, Jeanine, Rutten, Joost H.W.

Source: Journal of clinical lipidology. 17(3):401-405

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192643429.0x000001&indx=1&recIds=ETOCvdc_100192643429.0x000001

Evidence‐based rationale for low dose nivolumab in critically ill patients with sepsis‐induced immunosuppression

Authors: Haak, Demy A. C., Otten, Leila‐Sophie, Koenen, Hans J. P. M., Smeets, Ruben L., Piet, Berber, Pickkers, Peter, Kox, Matthijs, ter Heine, Rob

Source: Clinical and translational science. 16(6):978-986

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185317214.0x000001&indx=1&recIds=ETOCvdc_100185317214.0x000001

Early Eculizumab Withdrawal in Patients With Atypical Hemolytic Uremic Syndrome in Native Kidneys Is Safe and Cost-Effective: Results of the CUREiHUS Study

Authors: Bouwmeester, Romy N., Duineveld, Caroline, Wijnsma, Kioa L., Bemelman, Frederike J., van der Heijden, Joost W., van Wijk, Joanna A.E., Bouts, Antonia H.M., van de Wetering, Jacqueline, Dorresteijn, Eiske, Berger, Stefan P., Gracchi, Valentina, van Zuilen, Arjan D., Keijzer-Veen, Mandy G., de Vries, Aiko P.J., van Rooij, Roos W.G., Engels, Flore A.P.T., Altena, Wim, de Wildt, Renée, van Kempen, Evy, Adang, Eddy M., ter Avest, Mendy, ter Heine, Rob, Volokhina, Elena B., van den Heuvel, Lambertus P.W.J., Wetzels, Jack F.M., van de Kar, Nicole C.A.J.

Source: Kidney international reports. 8(1):91-102

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178939432.0x000001&indx=1&recIds=ETOCvdc_100178939432.0x000001

First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

Authors: Smit, Merel J, Sander, Adam F, Ariaans, Maud B P A, Fougeroux, Cyrielle, Heinzel, Constanze, Fendel, Rolf, Esen, Meral, Kremsner, Peter G, ter Heine, Rob, Wertheim, Heiman F, Idorn, Manja, Riis Paludan, Søren, Underwood, Alexander P, Binderup, Alekxander, Ramirez, Santseharay, Bukh, Jens, Soegaard, Max, Erdogan, Sayit M, Gustavsson, Tobias, Clemmensen, Stine, Theander, Thor G, Salanti, Ali, Hamborg, Mette, de Jongh, Willem A, McCall, Matthew B B, Nielsen, Morten A, Mordmüller, Benjamin G, Dagil, Robert, Goksøyr, Louise, Hulen, Thomas M, Janitzek, Christoph, Jensen, Daniel S, Justesen, Sune, Khalifé, Paul K, Kreidenweiss, Andrea, Lança, Telma, Lie-Andersen, Olivia, Teelen, Karina, Vidal-Calvo, Elena, Paludan, Søren Riis

Source: In The Lancet Microbe March 2023 4(3):e140-e148

Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose-escalation, phase 1 trial in healthy malaria-naive adults

Authors: van der Boor, Saskia C ^*, Smit, Merel J ^*, van Beek, Stijn W, Ramjith, Jordache, Teelen, Karina, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, Pickkers, Peter, Wu, Yimin, Locke, Emily, Lee, Shwu-Maan, Aponte, John, King, C Richter, Birkett, Ashley J, Miura, Kazutoyo, Ayorinde, Morolayo A, Sauerwein, Robert W, ter Heine, Rob, Ockenhouse, Christian F, Bousema, Teun, Jore, Matthijs M, McCall, Matthew B B ^*

Source: In The Lancet Infectious Diseases November 2022 22(11):1596-1605

Model-informed development of a cost-saving dosing regimen for enfortumab vedotin.

Authors: Op 't Hoog, Catharina JP, Rieborn, Amy, Moes, Dirk Jan AR, Hendrikx, Jeroen JMA, van der Heijden, Michiel S., Franken, Mira D., van der Hulle, Tom, van Kruchten, Michel, Willemsen, Annelieke ECAB, Koolen, Stijn LW, Boerrigter, Emmy, ter Heine, Rob

Source: Cancer Chemotherapy & Pharmacology; 2/25/2025, Vol. 95 Issue 1, p1-8, 8p

Subject Terms: ANTIBODY-drug conjugates, OVERALL survival, DRUG prices, TRANSITIONAL cell carcinoma, BODY weight

Posaconazole bioavailability of the solid oral tablet is reduced during severe intestinal mucositis

Authors: Jansen, Anouk M.E., Muilwijk, Eline W., van der Velden, Walter J.F.M., Maertens, Johan A., Aerts, Robina, Colbers, Angela, Burger, David, Verweij, Paul E., ter Heine, Rob, Blijlevens, Nicole M.A., Brüggemann, Roger J.M.

Source: In Clinical Microbiology and Infection July 2022 28(7):1003-1009

Single low-dose tafenoquine combined with dihydroartemisinin–piperaquine to reduce Plasmodium falciparum transmission in Ouelessebougou, Mali: a phase 2, single-blind, randomised clinical trial

Authors: Stone, Will ^*, Mahamar, Almahamoudou, Smit, Merel J, Sanogo, Koualy, Sinaba, Youssouf, Niambele, Sidi M, Sacko, Adama, Keita, Sekouba, Dicko, Oumar M, Diallo, Makonon, Maguiraga, Seydina O, Samake, Siaka, Attaher, Oumar, Lanke, Kjerstin, ter Heine, Rob, Bradley, John, McCall, Matthew B B, Issiaka, Djibrilla, Traore, Sekou F, Bousema, Teun, Drakeley, Chris, Dicko, Alassane

Source: In The Lancet Microbe May 2022 3(5):e336-e347

HIV-1 pretreatment drug resistance negatively impacts outcomes of first-line antiretroviral treatment

Authors: Hermans, Lucas E., Hofstra, Laura M., Schuurman, Rob, Ter Heine, Rob, Burger, David M., Talboom, Stijn A.J., De Jong, Dorien, Tempelman, Hugo A., Venter, Willem D.F., Nijhuis, Monique, Wensing, Annemarie M.J.

Source: AIDS. 36(7):923-931

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194408523.0x000001&indx=1&recIds=ETOCvdc_100194408523.0x000001

A randomized study of intensified antiretroviral treatment monitoring versus standard-of-care for prevention of drug resistance and antiretroviral treatment switch

Authors: Hermans, Lucas E., Ter Heine, Rob, Schuurman, Rob, Tempelman, Hugo A., Burger, David M., Vervoort, Sigrid C.J.M., Deville, Walter L.J.M., De Jong, Dorien, Venter, Willem D.F., Nijhuis, Monique, Wensing, Annemarie M.J.

Source: AIDS. 36(14):1959-1968

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194418065.0x000001&indx=1&recIds=ETOCvdc_100194418065.0x000001

Meropenem to Treat Valproic Acid Intoxication

Authors: Smolders, Elise J., Ter Heine, Rob, Natsch, Stephanie, Kramers, Kees

Source: Therapeutic drug monitoring. 44(3):359-362

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152870941.0x000001&indx=1&recIds=ETOCvdc_100152870941.0x000001

Pharmacokinetic evaluation of twice-a-week micafungin for prophylaxis of invasive fungal disease in children with acute lymphoblastic leukaemia: a prospective observational cohort study

Authors: Bury, Didi, Wolfs, Tom F W, ter Heine, Rob, Muilwijk, Eline W, Tissing, Wim J E, Brüggemann, Roger J

Source: Journal of antimicrobial chemotherapy. 77(3):699-703

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142351787.0x000001&indx=1&recIds=ETOCvdc_100142351787.0x000001

Pyronaridine–artesunate or dihydroartemisinin–piperaquine combined with single low-dose primaquine to prevent Plasmodium falciparum malaria transmission in Ouélessébougou, Mali: a four-arm, single-blind, phase 2/3, randomised trial

Authors: Stone, William ^{*, *}, Mahamar, Almahamoudou ^*, Sanogo, Koualy, Sinaba, Youssouf, Niambele, Sidi M, Sacko, Adama, Keita, Sekouba, Youssouf, Ahamadou, Diallo, Makonon, Soumare, Harouna M, Kaur, Harparkash, Lanke, Kjerstin, ter Heine, Rob, Bradley, John, Issiaka, Djibrilla, Diawara, Halimatou, Traore, Sekou F, Bousema, Teun, Drakeley, Chris, Dicko, Alassane

Source: In The Lancet Microbe January 2022 3(1):e41-e51

High unbound flucloxacillin fraction in critically ill patients

Authors: Wallenburg, Eveline, ter Heine, Rob, de Lange, Dylan W, van Leeuwen, Henk, Schouten, Jeroen A, ten Oever, Jaap, Kolwijck, Eva, Burger, David M, Pickkers, Peter, Gieling, Emilie M, de Maat, Monique M, Frenzel, Tim, Brüggemann, Roger J

Source: Journal of antimicrobial chemotherapy. 76(12):3220-3228

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135769489.0x000001&indx=1&recIds=ETOCvdc_100135769489.0x000001

Azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a phase II randomised controlled trial.

Authors: Connon, Roisin, Olupot-Olupot, Peter, Pistorius, Arthur M. A., Okiror, William, Ssenyondo, Tonny, Muhindo, Rita, Uyoga, Sophie, Mpoya, Ayub, Williams, Thomas N., Gibb, Diana M., Walker, A. Sarah, ter Heine, Rob, George, Elizabeth C., Maitland, Kathryn

Source: BMC Medicine; 11/6/2024, Vol. 22 Issue 1, p1-15, 15p

Subject Terms: BACTERIAL diseases, MALARIA prevention, C-reactive protein, AZITHROMYCIN, AFRICANS

Model-informed dose optimization of mycophenolic acid in pediatric kidney transplant patients.

Authors: Heida, Astrid, Jager, Nynke G. L., Aarnoutse, Rob E., de Winter, Brenda C. M., de Jong, Huib, Keizer, Ron J., Cornelissen, Elisabeth A. M., ter Heine, Rob

Source: European Journal of Clinical Pharmacology; Nov2024, Vol. 80 Issue 11, p1761-1771, 11p

Subject Terms: KIDNEY transplantation, BIOLOGICAL models, RESEARCH funding, ACADEMIC medical centers, MYCOPHENOLIC acid, HUMAN beings, BODY weight, DESCRIPTIVE statistics, RESEARCH methodology, CONFIDENCE intervals, DATA analysis software, DRUG development, DRUG dosage, DRUG administration

Geographic Terms: NETHERLANDS

Personalised antimicrobial dosing: standing on the shoulders of giants

Authors: Wallenburg, Eveline, ter Heine, Rob, Schouten, Jeroen A., Brüggemann, Roger J.M.

Source: In International Journal of Antimicrobial Agents September 2020 56(3)