Maintenance and functional regulation of immune memory to COVID-19 vaccines in tissues

Authors: Davis-Porada, Julia ^{1, 2}, George, Alex B. ^{2, 4}, Lam, Nora ^{1, 3}, Caron, Daniel P. ¹, Gray, Joshua I. ¹, Huang, Jenny ⁴, Hwu, Jennifer ⁴, Wells, Steven B. ⁴, Matsumoto, Rei ⁵, Kubota, Masaru ⁵, Lee, YoonSeung ¹, Morrison-Colvin, Rory ¹, Jensen, Isaac J. ¹, Ural, Basak B. ¹, Shaabani, Namir ⁶, Weiskopf, Daniela ⁷, Grifoni, Alba ⁷, Sette, Alessandro ^{7, 8}, Szabo, Peter A. ¹, Teijaro, John R. ⁶, Sims, Peter A. ^{4, 9, 10, ∗}, Farber, Donna L. ^{1, 5, 10, 11, ∗∗}

Source: In Immunity 10 December 2024 57(12):2895-2913

Inhibition of SARS-CoV-2 growth in the lungs of mice by a peptide-conjugated morpholino oligomer targeting viral RNA

Authors: Sakai, Alexandra, Singh, Gagandeep, Khoshbakht, Mahsa, Bittner, Scott, Löhr, Christiane V., Diaz-Tapia, Randy, Warang, Prajakta, White, Kris, Luo, Luke Le, Tolbert, Blanton, Blanco, Mario, Chow, Amy, Guttman, Mitchell, Li, Cuiping, Bao, Yiming, Ho, Joses, Maurer-Stroh, Sebastian, Chatterjee, Arnab, Chanda, Sumit, García-Sastre, Adolfo, Schotsaert, Michael, Teijaro, John R., Moulton, Hong M., Stein, David A.

Source: In Molecular Therapy - Nucleic Acids 10 December 2024 35(4)

The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid–sensing TLRs and ligands to endolysosomes

Authors: Rimann, Ivo, Gonzalez-Quintial, Rosana, Baccala, Roberto, Kiosses, William B., Teijaro, John R., Parker, Christopher G., Li, Xiaohong, Beutler, Bruce, Kono, Dwight H., Theofilopoulos, Argyrios N.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Apr 01. 119(14), 1-9.

Access URL: https://www.jstor.org/stable/27151221

Proteomic discovery of chemical probes that perturb protein complexes in human cells

Authors: Lazear, Michael R., Remsberg, Jarrett R., Jaeger, Martin G., Rothamel, Katherine, Her, Hsuan-lin, DeMeester, Kristen E., Njomen, Evert, Hogg, Simon J., Rahman, Jahan, Whitby, Landon R., Won, Sang Joon, Schafroth, Michael A., Ogasawara, Daisuke, Yokoyama, Minoru, Lindsey, Garrett L., Li, Haoxin, Germain, Jason, Barbas, Sabrina, Vaughan, Joan, Hanigan, Thomas W., Vartabedian, Vincent F., Reinhardt, Christopher J., Dix, Melissa M., Koo, Seong Joo, Heo, Inha, Teijaro, John R., Simon, Gabriel M., Ghosh, Brahma, Abdel-Wahab, Omar, Ahn, Kay, Saghatelian, Alan, Melillo, Bruno, Schreiber, Stuart L., Yeo, Gene W., Cravatt, Benjamin F.

Source: In Molecular Cell 18 May 2023 83(10):1725-1742

B cell–derived IL-27 promotes control of persistent LCMV infection

Authors: Pratumchai, Isaraphorn, Zak, Jaroslav, Huang, Zhe, Min, Booki, Oldstone, Michael B. A., Teijaro, John R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Jan . 119(3), 1-8.

Access URL: https://www.jstor.org/stable/27112968

Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse.

Authors: Nennig, Kylie¹, Murthy, Satyapramod², Maloney, Sara¹, Shaw, Teressa M.¹, Sharobim, Mark¹, Matkovic, Eduard¹, Fadiran, Simi¹, Larsen, Malorie¹, Ramuta, Mitchell D.¹, Kim, Arthur S.^3,4, Teijaro, John R.³, Grove, Joe⁵, Stremlau, Matthew⁶, Sharma, Himanshu², Trivedi, Sheetal², Blum, Michael J.⁷, O'Connor, David H.¹, Hyde, Jennifer L.⁸, Stapleton, Jack T.⁹, Kapoor, Amit^2,10

Source: PLoS Pathogens; 8/28/2024, Vol. 20 Issue 8, p1-24, 24p

Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways

Authors: Zhao, Fangzhu, Keating, Celina, Ozorowski, Gabriel, Shaabani, Namir, Francino-Urdaniz, Irene M., Barman, Shawn, Limbo, Oliver, Burns, Alison, Zhou, Panpan, Ricciardi, Michael J., Woehl, Jordan, Tran, Quoc, Turner, Hannah L., Peng, Linghang, Huang, Deli, Nemazee, David, Andrabi, Raiees, Sok, Devin, Teijaro, John R., Whitehead, Timothy A., Ward, Andrew B., Burton, Dennis R., Jardine, Joseph G.

Source: In iScience 16 September 2022 25(9)

Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2

Authors: Zhou, Xiaojuan, Ma, Fengge, Xie, Jun, Yuan, Meng, Li, Yunqiao, Shaabani, Namir, Zhao, Fangzhu, Huang, Deli, Wu, Nicholas C., Lee, Chang-Chun D., Liu, Hejun, Li, Jiali, Chen, Zhonghui, Hong, Yazhen, Liu, Wen-Hsien, Xiao, Nengming, Burton, Dennis R., Tu, Haijian, Li, Hang, Chen, Xin, Teijaro, John R., Wilson, Ian A., Xiao, Changchun, Huang, Zhe

Source: In Cell Reports 11 May 2021 35(6)

Detecting Tumor Antigen-Specific T Cells via Interaction-Dependent Fucosyl-Biotinylation

Authors: Liu, Zilei, Li, Jie P., Chen, Mingkuan, Wu, Mengyao, Shi, Yujie, Li, Wei, Teijaro, John R., Wu, Peng

Source: In Cell 12 November 2020 183(4):1117-1133

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Authors: Vinogradova, Ekaterina V., Zhang, Xiaoyu, Remillard, David, Lazar, Daniel C., Suciu, Radu M., Wang, Yujia, Bianco, Giulia, Yamashita, Yu, Crowley, Vincent M., Schafroth, Michael A., Yokoyama, Minoru, Konrad, David B., Lum, Kenneth M., Simon, Gabriel M., Kemper, Esther K., Lazear, Michael R., Yin, Sifei, Blewett, Megan M., Dix, Melissa M., Nguyen, Nhan, Shokhirev, Maxim N., Chin, Emily N., Lairson, Luke L., Melillo, Bruno, Schreiber, Stuart L., Forli, Stefano, Teijaro, John R., Cravatt, Benjamin F.

Source: In Cell 20 August 2020 182(4):1009-1026

The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation

Authors: Xie, Jun, Du, Ying, Liu, Dewang, Wu, Jianfeng, Yang, Kang, He, Xiaoyu, Zhao, Jiayi, Hong, Peicheng, Liao, Kunyu, Zhang, Huanrong, Hong, Yazhen, Teijaro, John R., Kang, Seung Goo, Xiao, Changchun, Liu, Wen-Hsien

Source: Cell reports. 42(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196077520.0x000001&indx=1&recIds=ETOCvdc_100196077520.0x000001

Autoimmunity-associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity.

Authors: Orozco, Robin C.^1,2, Orozco.robin@ku.edu, Marquardt, Kristi¹, Pratumchai, Isaraphorn¹, Shaikh, Anam Fatima², Mowen, Kerri¹, Domissy, Alain³, Teijaro, John R.¹, Sherman, Linda A.¹, Orozco.robin@ku.edu

Source: PLoS Pathogens; 3/21/2024, Vol. 20 Issue 3, p1-28, 28p

Discovery of Small Molecules for the Reversal of T Cell Exhaustion

Authors: Marro, Brett S., Zak, Jaroslav, Zavareh, Reza Beheshti, Teijaro, John R., Lairson, Luke L., Oldstone, Michael B.A.

Source: In Cell Reports 3 December 2019 29(10):3293-3302

IL-27 promotes the expansion of self-renewing CD8^+ T cells in persistent viral infection

Authors: Huang, Zhe, Zak, Jaroslav, Pratumchai, Isaraphorn, Shaabani, Namir, Vartabedian, Vincent F., Nguyen, Nhan, Wu, Tuoqi, Xiao, Changchun, Teijaro, John R.

Source: Journal of experimental medicine. 216(8):1791-1808

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621057002&indx=1&recIds=ETOCRN621057002

Taking down defenses to improve vaccines

Authors: Teijaro, John R., Burton, Dennis R.

Source: Science, 2018 Jan . 359(6373), 277-278.

Access URL: https://www.jstor.org/stable/26401292

Targeted desialylation and cytolysis of tumour cells by fusing a sialidase to a bispecific T-cell engager.

Authors: Yang, Zhuo, Hou, Yingqin, Grande, Geramie, Cho, Jong Hyun, Wang, Chao, Shi, Yujie, Zak, Jaroslav, Wan, Yue, Qin, Ke, Liu, Dongfang, Teijaro, John R., Lerner, Richard A., Wu, Peng

Source: Nature Biomedical Engineering; May2024, Vol. 8 Issue 5, p499-512, 14p

PTPN22 contributes to exhaustion of T lymphocytes during chronic viral infection

Authors: Maine, Christian J., Teijaro, John R., Marquardt, Kristi, Sherman, Linda A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Nov . 113(46), E7231-E7239.

Access URL: https://www.jstor.org/stable/26472517

Type I interferons in viral control and immune regulation

Authors: Teijaro, John R

Source: In Current Opinion in Virology February 2016 16:31-40

Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly.

Authors: Stanton, Caroline, Sun, Jie, Nutsch, Kayla, Rosarda, Jessica D., Nguyen, Thu, Li-Ma, Chloris, Njomen, Evert, Melillo, Bruno, Kutseikin, Sergei, Saez, Enrique, Cravatt, Benjamin F., Teijaro, John R., Wiseman, R. Luke, Bollong, Michael J.

Source: ACS Chemical Biology; 2/16/2024, Vol. 19 Issue 2, p254-265, 12p

S1PR1-mediated IFNAR1 degradation modulates plasmacytoid dendritic cell interferon-α autoamplification

Authors: Teijaro, John R., Studer, Sean, Leaf, Nora, Kiosses, William B., Nguyen, Nhan, Matsuki, Kosuke, Negishi, Hideo, Taniguchi, Tadatsugu, Oldstone, Michael B. A., Rosen, Hugh

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Feb 01. 113(5), 1351-1356.

Access URL: https://www.jstor.org/stable/26467605