Biased signaling in drug discovery and precision medicine

Authors: Ji, Ren-Lei, Tao, Ya-Xiong ^⁎

Source: In Pharmacology and Therapeutics April 2025 268

SHU9119 and MBP10 are biased ligands at the human melanocortin-4 receptor

Authors: Dai, Han-Chuan, Ji, Ren-Lei, Tao, Ya-Xiong

Source: In Biochemical Pharmacology October 2024 228

Hypothalamic-pituitary-derived melanocortin axis links to myelopoiesis and immunotherapy

Authors: Zhang, Chao, Tao, Ya-Xiong

Source: In The Innovation 10 July 2023 4(4)

Pharmacology of orange-spotted grouper (Epinephelus coioides) melanocortin-5 receptor and its modulation by Mrap2

Authors: Ji, Li-Qin, Rao, Ying-Zhu, Zhang, Yong, Chen, Rong, Tao, Ya-Xiong

Source: In General and Comparative Endocrinology 1 February 2023 332

Regulation of melanocortin-5 receptor pharmacology by two isoforms of MRAP2 in ricefield eel (Monopterus albus)

Authors: Liu, Ting, Yi, Ti-Lin, Yang, Dai-Qin, Tao, Ya-Xiong

Source: In General and Comparative Endocrinology 1 December 2021 314

Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases

Authors: Yang, Li-Kun, Hou, Zhi-Shuai, Tao, Ya-Xiong

Source: In BBA - Molecular Basis of Disease 1 January 2021 1867(1)

Exploring Pleiotropic Functions of Canine β‐Defensin 103: Nasal Cavity Expression, Antimicrobial Activity, and Melanocortin Receptor Activity

Authors: Aono, Shelly, Dennis, John C., He, Shan, Wang, Wei, Tao, Ya‐Xiong, Morrison, Edward E.

Source: Anatomical record. 304(1):210-221

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100113366221.0x000001&indx=1&recIds=ETOCvdc_100113366221.0x000001

Nerve growth factor in metabolic complications and Alzheimer's disease: Physiology and therapeutic potential

Authors: Ding, Xiao-Wen, Li, Rongzi, Geetha, Thangiah, Tao, Ya-Xiong, Babu, Jeganathan Ramesh

Source: In BBA - Molecular Basis of Disease 1 October 2020 1866(10)

Biased signaling in fish melanocortin-4 receptors (MC4Rs): Divergent pharmacology of four ligands on spotted scat (Scatophagus argus) and grass carp (Ctenopharyngodon idella) MC4Rs

Authors: Yang, Zhao, Liang, Xu-Fang, Li, Guang-Li, Tao, Ya-Xiong

Source: In Molecular and Cellular Endocrinology 15 September 2020 515

Regulation of melanocortin-1 receptor pharmacology by melanocortin receptor accessory protein 2 in orange-spotted grouper (Epinephelus coioides)

Authors: Ji, Li-Qin, Rao, Ying-Zhu, Zhang, Yong, Chen, Rong, Tao, Ya-Xiong

Source: In General and Comparative Endocrinology 1 January 2020 285

Orange-spotted grouper melanocortin-4 receptor: Modulation of signaling by MRAP2

Authors: Rao, Ying-Zhu, Chen, Rong, Zhang, Yong, Tao, Ya-Xiong

Source: In General and Comparative Endocrinology 1 December 2019 284

Characterization of channel catfish (Ictalurus punctatus) melanocortin-3 receptor reveals a potential network in regulation of energy homeostasis

Authors: Yang, Li-Kun, Zhang, Zheng-Rui, Wen, Hai-Shen, Tao, Ya-Xiong

Source: In General and Comparative Endocrinology 1 June 2019 277:90-103

Pharmacology of the giant panda (Ailuropoda melanoleuca) melanocortin-3 receptor

Authors: Zhang, Hai-Jie, Xie, Hua-Jie, Wang, Wei, Wang, Zhi-Qiang, Tao, Ya-Xiong

Source: In General and Comparative Endocrinology 1 June 2019 277:73-81

Effects of photoperiod and light Spectrum on growth performance, digestive enzymes, hepatic biochemistry and peripheral hormones in spotted sea bass (Lateolabrax maculatus)

Authors: Hou, Zhi-Shuai, Wen, Hai-Shen, Li, Ji-Fang, He, Feng, Li, Yun, Qi, Xin, Zhao, Ji, Zhang, Kai-Qiang, Tao, Ya-Xiong

Source: In Aquaculture 30 May 2019 507:419-427

Are Melanocortin Receptors Present in Extant Protochordates?

Authors: Ji, Ren-Lei, Jiang, Shan-Shan, Kleinau, Gunnar, Scheerer, Patrick, Tao, Ya-Xiong

Source: Biomolecules (2218-273X); Sep2024, Vol. 14 Issue 9, p1120, 15p

Subject Terms: G protein coupled receptors, LIGANDS (Biochemistry), CIONA intestinalis, AMPHIOXUS, TUNICATA

Mitochondrial Adaptation in Skeletal Muscle: Impact of Obesity, Caloric Restriction, and Dietary Compounds.

Authors: Jun, Lauren, Tao, Ya-Xiong, Geetha, Thangiah, Babu, Jeganathan Ramesh

Source: Current Nutrition Reports; Sep2024, Vol. 13 Issue 3, p500-515, 16p

Ligands for Melanocortin Receptors: Beyond Melanocyte-Stimulating Hormones and Adrenocorticotropin.

Authors: Yuan, Xiao-Chen¹ (AUTHOR), Tao, Ya-Xiong² (AUTHOR) taoyaxi@auburn.edu

Source: Biomolecules (2218-273X). Oct2022, Vol. 12 Issue 10, pN.PAG-N.PAG. 23p.

Subject Terms: *MELANOCORTIN receptors, *CELL receptors, *DEFENSINS, *ADRENOCORTICOTROPIC hormone, *LIGANDS (Biochemistry), *HORMONE receptors, *SMALL molecules, *HOMEOSTASIS

Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure

Authors: Li, Zhen, Organ, Chelsea L., Kang, Jianming, Polhemus, David J., Trivedi, Rishi K., Sharp, Thomas E., III, Jenkins, Jack S., Tao, Ya-xiong, Xian, Ming, Lefer, David J.

Source: In JACC: Basic to Translational Science December 2018 3(6):796-809

Regulation of prostate cancer by hormone-responsive G protein-coupled receptors

Authors: Wang, Wei, Chen, Zhao-Xia, Guo, Dong-Yu, Tao, Ya-Xiong

Source: In Pharmacology and Therapeutics November 2018 191:135-147

Expression of estrogen receptors in female rainbow trout (Oncorhynchus mykiss) during first ovarian development and under dense rearing condition

Authors: Hou, Zhi-Shuai, Wen, Hai-Shen, Li, Ji-Fang, He, Feng, Li, Yun, Tao, Ya-Xiong

Source: In General and Comparative Endocrinology 1 April 2018 259:1-11