The host-targeting compound peruvoside has a broad-spectrum antiviral activity against positive-sense RNA viruses

Authors: Wu, Kan Xing, Yogarajah, Thinesshwary, Loe, Marcus Wing Choy, Kaur, Parveen, Lee, Regina Ching Hua, Mok, Chee Keng, Wong, Yi Hao, Phuektes, Patchara, Yeo, Li Sze, Chow, Vincent T.K., Tan, Yong Wah, Chu, Justin Jang Hann

Source: Acta pharmaceutica sinica B. 13(5):2039-2055

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Non-enveloped virus inactivation potency of sodium dodecyl sulfate with citric and glutamic acids.

Authors: Tan, Yong Wah, Bok, Chwee Fern, Lim, Brenda Jun Fang, Kong, Li Ying, Goo, Kian Sim, Ishida, Yoshiki, Liu, Jiquan, Chua, Chun Song, Chu, Justin Jang Hann

Source: Frontiers in Microbiology; 2025, p1-8, 8p

Subject Terms: SODIUM dodecyl sulfate, GLUTAMIC acid, VIRUS inactivation, ANIONIC surfactants, ORGANIC acids

Exploring non-alcohol-based disinfectant: virucidal efficacy of arginine and Zinc chloride against feline calicivirus.

Authors: Kong Li Ying, Marcella, Masirevic, Srdan, Tan, Yong Wah, Marzinek, Jan K., Fox, Stephen John, Verma, Chandra S., Bond, Peter J., Ishida, Yoshiki, Liu, Jiquan, Chua, Chun Song, Chu, Justin Jang Hann

Source: Frontiers in Microbiology; 2025, p1-10, 10p

Subject Terms: ZINC chloride, TRANSMISSION electron microscopy, CALICIVIRUSES, LIGHT scattering, VACCINE effectiveness, NOROVIRUSES

Coronavirus infectious bronchitis virus non-structural proteins 8 and 12 form stable complex independent of the non-translated regions of viral RNA and other viral proteins

Authors: Tan, Yong Wah, Fung, To Sing, Shen, Hongyuan, Huang, Mei, Liu, Ding Xiang

Source: In Virology 1 January 2018 513:75-84

An evaluation of Chloroquine as a broad-acting antiviral against Hand, Foot and Mouth Disease

Authors: Tan, Yong Wah, Yam, Wan Keat, Sun, Jialei, Chu, Justin Jang Hann

Source: ANTIVIRAL RESEARCH. 149:143-149

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Novel capsid binder and PI4KIIIbeta inhibitors for EV-A71 replication inhibition.

Authors: Tan, Yong Wah¹, Yam, Wan Keat¹, Kooi, Rachel Jia Wen¹, Westman, Jacob², Arbrandt, Gustav², Chu, Justin Jang Hann^1,3 jhchu@imcb.a-star.edu.sg

Source: Scientific Reports. 5/6/2021, Vol. 11 Issue 1, p1-11. 11p.

Subject Terms: *HAND, foot & mouth disease, *VIRAL replication, *PHOSPHATIDYLINOSITOL 3-kinases, *ENZYME inhibitors, *IMMUNOCOMPROMISED patients, *VIRUS diseases

Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2–P4 study

Authors: Ang, Melgious J. Y., Lau, Qiu Ying, Ng, Fui Mee, Then, Siew Wen, Poulsen, Anders, Cheong, Yuen Kuen, Ngoh, Zi Xian, Tan, Yong Wah, Peng, Jianhe, Keller, Thomas H., Hill, Jeffrey, Chu, Justin J. H., Brian Chia, C. S.

Source: Journal of enzyme inhibition and medicinal chemistry. 31(2):332-339

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Inhibition of enterovirus VP4 myristoylation is a potential antiviral strategy for hand, foot and mouth disease

Authors: Tan, Yong Wah, Hong, Wan Jin, Chu, Justin Jang Hann

Source: ANTIVIRAL RESEARCH. 133:191-195

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095999441.0x000001&indx=1&recIds=ETOCvdc_100095999441.0x000001

Potential relevance of salivary legumain for the clinical diagnostic of hand, foot, and mouth disease.

Authors: Tan, Yong Wah, Teo, Fiona Mei Shan, Ler, Siok Ghee, Alli‐Shaik, Asfa, Nyo, Min, Chong, Chia Yin, Tan, Natalie Woon Hui, Wang, Robert Y. L., Gunaratne, Jayantha, Chu, Justin Jang Hann

Source: Journal of Medical Virology; Nov2023, Vol. 95 Issue 11, p1-9, 9p

Subject Terms: ORAL diseases, RECEIVER operating characteristic curves, CHEMICAL labeling

Geographic Terms: TAIWAN, SINGAPORE

Ternary dispersions to enhance solubility of poorly water soluble antioxidants

Authors: Kakran, Mitali, Sahoo, Nanda Gopal, Tan, Yong Wah, Li, Lin

Source: In Colloids and Surfaces A: Physicochemical and Engineering Aspects 20 September 2013 433:111-121

Drug repurposing of pyrimidine analogs as potent antiviral compounds against human enterovirus A71 infection with potential clinical applications

Authors: Sun, Jialei, Yogarajah, Thinesshwary, Lee, Regina Ching Hua, Kaur, Parveen, Inoue, Masafumi, Tan, Yong Wah, Chu, Justin Jang Hann

Source: Scientific reports. 10(1)

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Protecting the most vulnerable from hand, foot, and mouth disease

Authors: Tan, Yong Wah, Chu, Justin Jang Hann

Source: Lancet infectious diseases. 21(3):308-309

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136207709.0x000001&indx=1&recIds=ETOCvdc_100136207709.0x000001

In utero infection of Zika virus leads to abnormal central nervous system development in mice

Authors: Zhang, Wei, Tan, Yong Wah, Yam, Wan Keat, Tu, Haitao, Qiu, Lifeng, Tan, Eng King, Chu, Justin Jang Hann, Zeng, Li

Source: Scientific reports. 9(1)

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Evaluation of In Vitro and In Vivo Antiviral Activities of Vitamin D for SARS-CoV-2 and Variants.

Authors: Mok, Chee-Keng, Ng, Yan Ling, Ahidjo, Bintou Ahmadou, Aw, Zhen Qin, Chen, Huixin, Wong, Yi Hao, Lee, Regina Ching Hua, Loe, Marcus Wing Choy, Liu, Jing, Tan, Kai Sen, Kaur, Parveen, Wang, De Yun, Hao, Erwei, Hou, Xiaotao, Tan, Yong Wah, Deng, Jiagang, Chu, Justin Jang Hann

Source: Pharmaceutics; Mar2023, Vol. 15 Issue 3, p925, 20p

Subject Terms: VITAMIN D, PEPTIDE antibiotics, SARS-CoV-2, VITAMIN D receptors, ANTIVIRAL agents, ANTIMICROBIAL peptides, VITAMIN D metabolism, AVIAN influenza

The Nucleocapsid Protein of Coronavirus Infectious Bronchitis Virus: Crystal Structure of Its N-Terminal Domain and Multimerization Properties

Authors: Fan, Hui, Ooi, Amy, Tan, Yong Wah, Wang, Sifang, Fang, Shouguo, Liu, Ding Xiang, Lescar, Julien

Source: In Structure 2005 13(12):1859-1868

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The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain.

Authors: Guo, Huichen, Huang, Mei, Yuan, Quan, Wei, Yanquan, Gao, Yuan, Mao, Lejiao, Gu, Lingjun, Tan, Yong Wah, Zhong, Yanxin, Liu, Dingxiang, Sun, Shiqi

Source: PLoS ONE; 1/12/2017, Vol. 12 Issue 1, p1-12, 12p

Subject Terms: LIPID rafts, CELL culture, CORONAVIRUS diseases, BRONCHITIS, VIRAL nonstructural proteins

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