A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis

Authors: Rajwani, Rahim, Galata, Chala, Lee, Annie Wing Tung, So, Pui-Kin, Leung, Kenneth Siu Sing, Tam, Kingsley King Gee, Shehzad, Sheeba, Ng, Timothy Ting Leung, Zhu, Li, Lao, Hiu Yin, Chan, Chloe Toi-Mei, Leung, Jake Siu-Lun, Lee, Lam-Kwong, Wong, Kin Chung, Yam, Wing Cheong, Siu, Gilman Kit-Hang

Source: Virulence. 13(1):1088-1100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174030429.0x000001&indx=1&recIds=ETOCvdc_100174030429.0x000001

Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?

Authors: Siu, Gilman Kit-Hang, Lee, Lam-Kwong, Leung, Kenneth Siu-Sing, Leung, Jake Siu-Lun, Ng, Timothy Ting-Leung, Chan, Chloe Toi-Mei, Tam, Kingsley King-Gee, Lao, Hiu-Yin, Wu, Alan Ka-Lun, Yau, Miranda Chong-Yee, Lai, Yvette Wai-Man, Fung, Kitty Sau-Chun, Chau, Sandy Ka-Yee, Wong, Barry Kin-Chung, To, Wing-Kin, Luk, Kristine, Ho, Alex Yat-Man, Que, Tak-Lun, Yip, Kam-Tong, Yam, Wing Cheong, Shum, David Ho-Keung, Yip, Shea Ping

Source: Emerging microbes & infections. 9(1):2497-2500

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117719491.0x000001&indx=1&recIds=ETOCvdc_100117719491.0x000001

Diagnostic evaluation of an in-house developed single-tube, duplex, nested IS6110 real-time PCR assay for rapid pulmonary tuberculosis diagnosis

Authors: Leung, Kenneth Siu-Sing, Siu, Gilman Kit-Hang, Tam, Kingsley King-Gee, Ho, Pak-Leung, Wong, Samson Sai-Yin, Leung, Eunice Ka-Chun, Yu, Shi Hui, Ma, Oliver Chiu-Kit, Yam, Wing-Cheong

Source: In Tuberculosis September 2018 112:120-125

Direct detection of Mycobacterium tuberculosis and drug resistance in respiratory specimen using Abbott Realtime MTB detection and RIF/INH resistance assay

Authors: Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, To, Sabrina Wai-Chi, Siu, Gilman Kit-Hang, Lau, Terrence Chi-Kong, Shek, Victor Chi-Man, Tse, Cindy Wing-Sze, Wong, Samson Sai-Yin, Ho, Pak-Leung, Yam, Wing-Cheong

Source: Diagnostic microbiology and infectious disease. 89(2):118-124

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100061555437.0x000001&indx=1&recIds=ETOCvdc_100061555437.0x000001

Evaluation of Mycobacterium tuberculosis enrichment in metagenomic samples using ONT adaptive sequencing and amplicon sequencing for identification and variant calling.

Authors: Su, Junhao, Lui, Wui Wang, Lee, YanLam, Zheng, Zhenxian, Siu, Gilman Kit-Hang, Ng, Timothy Ting-Leung, Zhang, Tong, Lam, Tommy Tsan-Yuk, Lao, Hiu-Yin, Yam, Wing-Cheong, Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Lam, Tak-Wah, Leung, Amy Wing-Sze, Luo, Ruibang

Source: Scientific Reports; 3/31/2023, Vol. 13 Issue 1, p1-10, 10p

Subject Terms: MYCOBACTERIUM tuberculosis, DRUG resistance in microorganisms, METAGENOMICS, DETECTION limit, BACTERIAL cultures, TUBERCULOSIS, IDENTIFICATION

Company/Entity: UNIVERSITY of Oxford

Nosocomial Outbreak of Coronavirus Disease 2019 by Possible Airborne Transmission Leading to a Superspreading Event.

Authors: Cheng, Vincent Chi-Chung, Fung, Kitty Sau-Chun, Siu, Gilman Kit-Hang, Wong, Shuk-Ching, Cheng, Lily Shui-Kuen, Wong, Man-Sing, Lee, Lam-Kwong, Chan, Wan-Mui, Chau, Ka-Yee, Leung, Jake Siu-Lun, Chu, Allen Wing-Ho, Chan, Wai-Shan, Lu, Kelvin Keru, Tam, Kingsley King-Gee, Ip, Jonathan Daniel, Leung, Kenneth Siu-Sing, Lung, David Christopher, Tse, Herman, To, Kelvin Kai-Wang, Yuen, Kwok-Yung

Source: Clinical Infectious Diseases; 9/15/2021, Vol. 73 Issue 6, pe1356-e1364, 9p

Subject Terms: CROSS infection prevention, AIR microbiology, DESCRIPTIVE statistics, PATIENT care, RNA, INFECTIOUS disease transmission, COVID-19 pandemic, COVID-19, GENOMES, SEQUENCE analysis, SARS-CoV-2

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Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?

Authors: Kit-Hang Siu, Gilman, Lam-Kwong Lee, Siu-Sing Leung, Kenneth, Jake Siu-Lun Leung, Ting-Leung Ng, Timothy, Chloe Toi-Mei Chan, Tam, Kingsley King-Gee, Hiu-Yin Lao, Ka-Lun Wu, Alan, Chong-Yee Yau, Miranda, Yvette Wai-Man Lai, Sau-Chun Fung, Kitty, Ka-Yee Chau, Sandy, Kin-Chung Wong, Barry, Wing-Kin To, Luk, Kristine, Yat-Man Ho, Alex, Tak-Lun Que, Kam-Tong Yip, Wing Cheong Yam

Source: Emerging Microbes & Infections; 2020, Vol. 9 Issue 1, p2497-2500, 4p

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Synergistic combination of antimicrobial peptide and isoniazid as inhalable dry powder formulation against multi-drug resistant tuberculosis.

Authors: Shao, Zitong^1,2 (AUTHOR), Tam, Kingsley King-Gee³ (AUTHOR), Achalla, V.P.K.² (AUTHOR), Woon, Esther C.Y.² (AUTHOR), Mason, A. James⁴ (AUTHOR), Chow, Shing Fung^1,5 (AUTHOR), Yam, Wing Cheong³ (AUTHOR), Lam, Jenny K.W.^1,2,5 (AUTHOR) jenny.lam@ucl.ac.uk

Source: International Journal of Pharmaceutics. Apr2024, Vol. 654, pN.PAG-N.PAG. 1p.

Subject Terms: *ANTIMICROBIAL peptides, *RIFAMPIN, *ISONIAZID, *MULTIDRUG-resistant tuberculosis, *SPRAY drying, *TUBERCULOSIS

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Screening Repurposed Antiviral Small Molecules as Antimycobacterial Compounds by a Lux-Based phoP Promoter-Reporter Platform.

Authors: Zhu, Li, Lee, Annie Wing-Tung, Wu, Kelvin Ka-Lok, Gao, Peng, Tam, Kingsley King-Gee, Rajwani, Rahim, Chaburte, Galata Chala, Ng, Timothy Ting-Leung, Chan, Chloe Toi-Mei, Lao, Hiu Yin, Yam, Wing Cheong, Kao, Richard Yi-Tsun, Siu, Gilman Kit Hang

Source: Antibiotics (2079-6382); Mar2022, Vol. 11 Issue 3, p369, 1p

Subject Terms: SMALL molecules, BCG vaccines, MYCOBACTERIUM tuberculosis, RNA sequencing, THERAPEUTICS, TUBERCULOSIS

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Direct Detection of Pyrazinamide Resistance in Mycobacterium tuberculosisby Use of pncAPCR Sequencing

Authors: Tam, Kingsley King-Gee, Leung, Kenneth Siu-Sing, Siu, Gilman Kit-Hang, Chang, Kwok-Chiu, Wong, Samson Sai-Yin, Ho, Pak-Leung, Leung, Eunice Ka-Chun, Yam, Wing-Cheong

Source: Journal of Clinical Microbiology; June 2019, Vol. 57 Issue: 8

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