Strategic targeting of Cas9 nickase expands tandem gene arrays

Authors: Takesue, Hiroaki ¹, Okada, Satoshi ¹, Doi, Goro ¹, Sugiyama, Yuki ¹, Kusumoto, Emiko ¹, Ito, Takashi ^{1, 2, ∗}

Source: In Cell Genomics 9 April 2025 5(4)

Exploiting mechanisms for hierarchical branching structure of lung airway.

Authors: Takigawa-Imamura, Hisako, Fumoto, Katsumi, Takesue, Hiroaki, Miura, Takashi

Source: PLoS ONE; 8/30/2024, Vol. 19 Issue 8, p1-24, 24p

Subject Terms: FIBROBLAST growth factors, CELL morphology, EPITHELIUM, WNT signal transduction, MATHEMATICAL analysis, LUNGS

Nucleosome Positioning and Gene Regulation of the SGLT2 Gene in the Renal Proximal Tubular Epithelial Cells

Authors: Takesue, Hiroaki, Hirota, Takeshi, Tachimura, Mami, Tokashiki, Ayane, Ieiri, Ichiro ^*

Source: In Molecular Pharmacology September 2018 94(3):953-962

Identification and Functional Characterization of Novel Nonsynonymous Variants in the Human Multidrug and Toxin Extrusion 2-K

Authors: Nishimura, Kenta, Ide, Ryosuke, Hirota, Takeshi, Kawazu, Kana, Kodama, Sho, Takesue, Hiroaki, Ieiri, Ichiro ^*

Source: In Drug Metabolism and Disposition September 2014 42(9):1432-1437

A cell based assay for evaluating binding and uptake of an antibody using hepatic nonparenchymal cells.

Authors: Noguchi, Yuki, Ozeki, Kazuhisa, Takesue, Hiroaki, Akita, Hidetaka

Source: Scientific Reports; 4/16/2021, Vol. 11 Issue 1, p1-11, 11p

Subject Terms: IMMUNOGLOBULIN G receptors, ENDOTHELIAL cells, PHARMACOKINETICS, FLOW cytometry, BIOLOGICALS, LIVER cells

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Transcriptional regulatory mechanisms of SGLT2 gene in human kidney

Authors: Takesue, Hiroaki, Hirota, Takeshi, Tachimura, Mami, Ieiri, Ichiro

Source: In Drug Metabolism and Pharmacokinetics January 2017 32(1) Supplement:S61-S61

Nucleosome Positioning and Gene Regulation of the SGLT2Gene in the Renal Proximal Tubular Epithelial Cells

Authors: Takesue, Hiroaki, Hirota, Takeshi, Tachimura, Mami, Tokashiki, Ayane, Ieiri, Ichiro

Source: Molecular Pharmacology; 2018, Vol. 94 Issue: 3 p953-962, 10p

Transcriptional regulatory mechanisms of SGLT2gene in human kidney

Authors: Takesue, Hiroaki, Hirota, Takeshi, Tachimura, Mami, Ieiri, Ichiro

Source: Drug Metabolism and Pharmacokinetics; January 2017, Vol. 32 Issue: 1, Number 1 Supplement 1 pS61-S61, 1p