Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice

Authors: Yukiko Harima, Masafumi Tsurutani, Serika Yamada, Shuntaro Uchida, Kengo Inada, Mitsue Hagihara, Satsuki Irie, Mayo Shigeta, Takaya Abe, Yukiko U. Inoue, Takayoshi Inoue, Kazunari Miyamichi

Source: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7a3a4af3bfdf468c9efdfe9f1e3ec343

Impact of Dupilumab on Skin Surface Lipid-RNA Profile in Severe Asthmatic Patients

Authors: Yoshihiko Sato, Hitoshi Sasano, Sumiko Abe, Yuuki Sandhu, Shoko Ueda, Sonoko Harada, Yuki Tanabe, Kyoko Shima, Tetsuya Kuwano, Yuya Uehara, Takayoshi Inoue, Ko Okumura, Kazuhisa Takahashi, Norihiro Harada

Source: Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11425-11437 (2024)

Subject Terms: asthma, dupilumab, skin surface lipid, sebum, type 2 inflammation, epithelial barrier function, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/10/680; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/da984dfaf08d4d7398c2ef59f2ef1e5f

Non-invasive SARS-CoV-2 RNA detection and human transcriptome analysis using skin surface lipids

Authors: Tetsuya Kuwano, Takayuki Kanno, Minoru Tobiume, Yuichiro Hirata, Harutaka Katano, Michiko Koga, Hiroyuki Nagai, Takeya Tsutsumi, Noritada Yoshikawa, Hiroshi Yotsuyanagi, Satoshi Kutsuna, Yusuke Miyazato, Noriko Kinoshita-Iwamoto, Norio Ohmagari, Taiichiro Kobayashi, Kazuaki Fukushima, Masaru Tanaka, Akifumi Imamura, Yui Ueda, Maeko Iwamura, Naoto Takada, Takayoshi Inoue, Tetsuro Matano, Ai Kawana-Tachikawa, Tadaki Suzuki

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)

Subject Terms: SARS-CoV-2, COVID-19, Skin, Sebum, Transcriptome, Skin surface lipid, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/dc046c1a8d294e0e859853be8a8c1d8e

Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation

Authors: Ken-ichi Dewa, Nariko Arimura, Wataru Kakegawa, Masayuki Itoh, Toma Adachi, Satoshi Miyashita, Yukiko U. Inoue, Kento Hizawa, Kei Hori, Natsumi Honjoya, Haruya Yagishita, Shinichiro Taya, Taisuke Miyazaki, Chika Usui, Shoji Tatsumoto, Akiko Tsuzuki, Hirotomo Uetake, Kazuhisa Sakai, Kazuhiro Yamakawa, Takuya Sasaki, Jun Nagai, Yoshiya Kawaguchi, Masaki Sone, Takayoshi Inoue, Yasuhiro Go, Noritaka Ichinohe, Kozo Kaibuchi, Masahiko Watanabe, Schuichi Koizumi, Michisuke Yuzaki, Mikio Hoshino

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/5cea2b1c16ce4725914dba62e22243c1

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Authors: Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, Mikio Hoshino, Akito Nakao, Yasuo Mori, Shigeo Okabe, Masayuki Matsushita, Anja Urbach, Yuta Katayama, Akinobu Matsumoto, Keiichi I Nakayama, Shota Katori, Takuya Sato, Takuji Iwasato, Haruko Nakamura, Yoshio Goshima, Matthieu Raveau, Tetsuya Tatsukawa, Kazuhiro Yamakawa, Noriko Takahashi, Haruo Kasai, Johji Inazawa, Ikuo Nobuhisa, Tetsushi Kagawa, Tetsuya Taga, Mohamed Darwish, Hirofumi Nishizono, Keizo Takao, Kiran Sapkota, Kazutoshi Nakazawa, Tsuyoshi Takagi, Haruki Fujisawa, Yoshihisa Sugimura, Kyosuke Yamanishi, Lakshmi Rajagopal, Nanette Deneen Hannah, Herbert Y Meltzer, Tohru Yamamoto, Shuji Wakatsuki, Toshiyuki Araki, Katsuhiko Tabuchi, Tadahiro Numakawa, Hiroshi Kunugi, Freesia L Huang, Atsuko Hayata-Takano, Hitoshi Hashimoto, Kota Tamada, Toru Takumi, Takaoki Kasahara, Tadafumi Kato, Isabella A Graef, Gerald R Crabtree, Nozomi Asaoka, Hikari Hatakama, Shuji Kaneko, Takao Kohno, Mitsuharu Hattori, Yoshio Hoshiba, Ryuhei Miyake, Kisho Obi-Nagata, Akiko Hayashi-Takagi, Léa J Becker, Ipek Yalcin, Yoko Hagino, Hiroko Kotajima-Murakami, Yuki Moriya, Kazutaka Ikeda, Hyopil Kim, Bong-Kiun Kaang, Hikari Otabi, Yuta Yoshida, Atsushi Toyoda, Noboru H Komiyama, Seth GN Grant, Michiru Ida-Eto, Masaaki Narita, Ken-ichi Matsumoto, Emiko Okuda-Ashitaka, Iori Ohmori, Tadayuki Shimada, Kanato Yamagata, Hiroshi Ageta, Kunihiro Tsuchida, Kaoru Inokuchi, Takayuki Sassa, Akio Kihara, Motoaki Fukasawa, Nobuteru Usuda, Tayo Katano, Teruyuki Tanaka, Yoshihiro Yoshihara, Michihiro Igarashi, Takashi Hayashi, Kaori Ishikawa, Satoshi Yamamoto, Naoya Nishimura, Kazuto Nakada, Shinji Hirotsune, Kiyoshi Egawa, Kazuma Higashisaka, Yasuo Tsutsumi, Shoko Nishihara, Noriyuki Sugo, Takeshi Yagi, Naoto Ueno, Tomomi Yamamoto, Yoshihiro Kubo, Rie Ohashi, Nobuyuki Shiina, Kimiko Shimizu, Sayaka Higo-Yamamoto, Katsutaka Oishi, Hisashi Mori, Tamio Furuse, Masaru Tamura, Hisashi Shirakawa, Daiki X Sato, Yukiko U Inoue, Takayoshi Inoue, Yuriko Komine, Tetsuo Yamamori, Kenji Sakimura, Tsuyoshi Miyakawa

Source: eLife, Vol 12 (2024)

Subject Terms: brain pH, lactate, metabolism, neuropsychiatric disorders, animal models, working memory, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/89376; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/15de117935204a21a8487997042e8094

Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids

Authors: Takayoshi Inoue, Tetsuya Kuwano, Yuya Uehara, Michiko Yano, Naoki Oya, Naoto Takada, Shodai Tanaka, Yui Ueda, Akira Hachiya, Yoshito Takahashi, Noriyasu Ota, Takatoshi Murase

Source: Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/5db75692677a4d3b88ee52ee465427ab

Non-invasive diagnostic tool for Parkinson’s disease by sebum RNA profile with machine learning

Authors: Yuya Uehara, Shin-Ichi Ueno, Haruka Amano-Takeshige, Shuji Suzuki, Yoko Imamichi, Motoki Fujimaki, Noriyasu Ota, Takatoshi Murase, Takayoshi Inoue, Shinji Saiki, Nobutaka Hattori

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8d5af2acda0847b59720e17cde503ddc

A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke

Authors: Toshiko Yamazawa, Takuya Kobayashi, Nagomi Kurebayashi, Masato Konishi, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, Ichizo Nishino, Shuichi Mori, Hiroto Iinuma, Noriaki Manaka, Hiroyuki Kagechika, Arkady Uryash, Jose Adams, Jose R. Lopez, Xiaochen Liu, Christine Diggle, Paul D. Allen, Sho Kakizawa, Keigo Ikeda, Bangzhong Lin, Yui Ikemi, Kazuto Nunomura, Shinsaku Nakagawa, Takashi Sakurai, Takashi Murayama

Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/afd2999f767e49b494c83b5f5e5c1a4b

Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety

Authors: Daiki X. Sato, Yukiko U. Inoue, Nahoko Kuga, Satoko Hattori, Kensaku Nomoto, Yuki Morimoto, Giovanni Sala, Hideo Hagihara, Takefumi Kikusui, Takuya Sasaki, Yuji Ikegaya, Tsuyoshi Miyakawa, Takayoshi Inoue, Masakado Kawata

Source: iScience, Vol 25, Iss 8, Pp 104800- (2022)

Subject Terms: Behavior genetics, Molecular Genetics, Molecular mechanism of behavior, Evolutionary biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222010720; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/003238d0a6fe457aabd60eabff60351f

The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

Authors: Yasunari Matsuzaka, Jun Tanihata, Yoshiko Ooshima, Daisuke Yamada, Masayuki Sekiguchi, Shouta Miyatake, Yoshitsugu Aoki, Mika Terumitsu, Ryu Yashiro, Hirofumi Komaki, Akihiko Ishiyama, Yasushi Oya, Yukiko U. Inoue, Takayoshi Inoue, Shin’ichi Takeda, Kazuo Hashido

Source: BMC Medicine, Vol 18, Iss 1, Pp 1-22 (2020)

Subject Terms: Duchenne muscular dystrophy, Neutral sphingomyelinase 2/sphingomyelin phosphodiesterase 3, CRISPR-Cas9, Inflammatory cytokine, Monocytes/macrophages, Membrane permeability, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12916-020-01805-5; https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/6c28ffb93b134c4a9132ccf90762f1c1

Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility

Authors: Yoneko Hayase, Shigeru Amano, Koichi Hashizume, Takashi Tominaga, Hiroyuki Miyamoto, Yukie Kanno, Yukiko Ueno-Inoue, Takayoshi Inoue, Mayumi Yamada, Shigehiro Ogata, Shabeesh Balan, Ken Hayashi, Yoshiki Miura, Kentaro Tokudome, Yukihiro Ohno, Takuma Nishijo, Toshihiko Momiyama, Yuchio Yanagawa, Akiko Takizawa, Tomoji Mashimo, Tadao Serikawa, Akihiro Sekine, Eiji Nakagawa, Eri Takeshita, Takeo Yoshikawa, Chikako Waga, Ken Inoue, Yu-ichi Goto, Yoichi Nabeshima, Nobuo Ihara, Kazuhiro Yamakawa, Shinichiro Taya, Mikio Hoshino

Source: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)

Subject Terms: DSCAML1, Seizure susceptibility, Ihara epileptic rat, Gabaergic neurons, Patient-type model mouse, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/83b2c846e60840adb9d55f24ef0bdf26

A new mouse model of Ehlers-Danlos syndrome generated using CRISPR/Cas9-mediated genomic editing

Authors: Yuko Nitahara-Kasahara, Shuji Mizumoto, Yukiko U. Inoue, Shota Saka, Guillermo Posadas-Herrera, Aki Nakamura-Takahashi, Yuki Takahashi, Ayana Hashimoto, Kohei Konishi, Shinji Miyata, Chiaki Masuda, Emi Matsumoto, Yasunobu Maruoka, Takahiro Yoshizawa, Toshiki Tanase, Takayoshi Inoue, Shuhei Yamada, Yoshihiro Nomura, Shin'ichi Takeda, Atsushi Watanabe, Tomoki Kosho, Takashi Okada

Source: Disease Models & Mechanisms, Vol 14, Iss 12 (2021)

Subject Terms: musculocontractural ehlers-danlos syndrome, dermatan sulfate, mouse model, crispr/cas9, myopathy, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/14/12/dmm048963; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/18ac308ec99e4737bca148fc2a47dc8c

Myopathy Associated With Dermatan Sulfate-Deficient Decorin and Myostatin in Musculocontractural Ehlers-Danlos Syndrome: A Mouse Model Investigation

Authors: Yuko Nitahara-Kasahara, Guillermo Posadas-Herrera, Shuji Mizumoto, Aki Nakamura-Takahashi, Yukiko U. Inoue, Takayoshi Inoue, Yoshihiro Nomura, Shin’ichi Takeda, Shuhei Yamada, Tomoki Kosho, Takashi Okada

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: Ehlers-Danlos syndrome, dermatan sulfate, dermatan 4-O-sulfotransferase 1, decorin, chst14 mutant mouse, myostatin, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.695021/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/628c0d523aa044b4b5618df49eddeeef

An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation

Authors: Yukiko U. Inoue, Yuki Morimoto, Mayumi Yamada, Ryosuke Kaneko, Kazumi Shimaoka, Shinji Oki, Mayuko Hotta, Junko Asami, Eriko Koike, Kei Hori, Mikio Hoshino, Itaru Imayoshi, Takayoshi Inoue

Source: Cells, Vol 10, Iss 5, p 1076 (2021)

Subject Terms: long ssDNA, phospho-PCR, knock-in, CRISPR/Cas9, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/5/1076; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/55a6df81cf8e4f539542750ba586a3e0

Additive dominant effect of a SOX10 mutation underlies a complex phenotype of PCWH

Authors: Yukiko Ito, Naoko Inoue, Yukiko U. Inoue, Shoko Nakamura, Yoshiki Matsuda, Masumi Inagaki, Takahiro Ohkubo, Junko Asami, Youhei W. Terakawa, Shinichi Kohsaka, Yu-ichi Goto, Chihiro Akazawa, Takayoshi Inoue, Ken Inoue

Source: Neurobiology of Disease, Vol 80, Iss , Pp 1-14 (2015)

Subject Terms: PCWH, Mutant SOX10, BAC transgenic mouse, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996115001606; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/3d3bfe4859514db89eb3827407b0bb9a

Visualization of trans homophilic interaction of clustered protocadherin in neurons.

Authors: Natsumi Hoshino, Takashi Kanadome, Tomomi Takasugi, Mizuho Itoh, Ryosuke Kaneko, Inoue, Yukiko U., Takayoshi Inoue, Takahiro Hirabayashi, Masahiko Watanabe, Tomoki Matsuda, Takeharu Nagai, Etsuko Tarusawa, Takeshi Yagi

Source: Proceedings of the National Academy of Sciences of the United States of America; 9/19/2023, Vol. 120 Issue 38, p1-17, 29p

Subject Terms: CADHERINS, CELLULAR recognition, FLUORESCENCE resonance energy transfer, NEURONS, FLUORESCENT proteins

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Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating.

Authors: Kotaro Oyama, Zeeb, Vadim, Toshiko Yamazawa, Nagomi Kurebayashi, Fuyu Kobirumaki-Shimozawa, Takashi Murayama, Hideto Oyamada, Satoru Noguchi, Takayoshi Inoue, Inoue, Yukiko U., Ichizo Nishino, Yoshie Harada, Fukuda, Norio, Ishiwata, Shin'ichi, Madoka Suzuki

Source: Proceedings of the National Academy of Sciences of the United States of America; 8/9/2022, Vol. 119 Issue 32, p1-31, 42p

Subject Terms: RYANODINE receptors, MALIGNANT hyperthermia, HEAT pulses, SKELETAL muscle, FLUORESCENT probes, PULSED power systems

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Targeting Neurons with Functional Oxytocin Receptors: A Novel Set of Simple Knock-In Mouse Lines for Oxytocin Receptor Visualization and Manipulation.

Authors: Inoue, Yukiko U., Hideki Miwa, Kei Hori, Ryosuke Kaneko, Yuki Morimoto, Eriko Koike, Junko Asami, Satoshi Kamijo, Mitsuhiko Yamada, Mikio Hoshino, Takayoshi Inoue

Source: eNeuro; Jan/Feb2022, Vol. 9 Issue 1, p1-15, 15p