OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Authors: Po‐Yuan Chen, Tai‐Ming Ko

Source: Advanced Intelligent Systems, Vol 7, Iss 3, Pp n/a-n/a (2025)

Subject Terms: in silico cell annotations, inflammations, machine learnings, oxidative stresses, reactive oxygen species, single‐cell transcriptional profiles, Computer engineering. Computer hardware, TK7885-7895, Control engineering systems. Automatic machinery (General), TJ212-225

File Description: electronic resource

Relation: https://doaj.org/toc/2640-4567

Access URL: https://doaj.org/article/0ab01508ec2a43ea807a2ef3e11fcf3d

Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin

Authors: Shu-Ing Toh, Johan Elaine Keisha, Yung-Lin Wang, Yi-Chi Pan, Yu-Heng Jhu, Po-Yun Hsiao, Wen-Ting Liao, Po-Yuan Chen, Tai-Ming Ko, Chin-Yuan Chang

Source: Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/2b645fd09cf843619395dcc8c81fbd8f

Whole transcriptome analysis to explore the impaired immunological features in critically ill elderly patients with sepsis

Authors: I-Chieh Chen, Hsin-Hua Chen, Yu-Han Jiang, Tzu-Hung Hsiao, Tai-Ming Ko, Wen-Cheng Chao

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)

Subject Terms: Sepsis, RNA-Seq, Elderly ICU patient, Differentially expressed genes, T-cell receptor, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/0dfcae6dd02244f5aaed9ae27bd1c008

Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration

Authors: Ke-Hsuan Wei, I-Ting Lin, Kaushik Chowdhury, Khai Lone Lim, Kuan-Ting Liu, Tai-Ming Ko, Yao-Ming Chang, Kai-Chien Yang, Shih-Lei (Ben) Lai

Source: eLife, Vol 12 (2023)

Subject Terms: macrophages, heart regeneration, scRNAseq, immune response, comparative analysis, myocardial infarction, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/84679; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/ffae0f3dc0c1435fbd4c1eda4e9edd50

Multimodal single‐cell analysis provides novel insights on ankylosing spondylitis in females

Authors: Hsin‐Hua Chen, Jing‐Rong Wang, Hsiao‐Ni Sung, Wen‐Cheng Chao, Kuan‐Ting Liu, Fang‐Ping Lin, Tai‐Ming Ko

Source: Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/8c3060e75f7f48959b2d028080721b63

Single‐cell profiling reveals novel cellular heterogeneity of monocytes during Hymenoptera venom allergy

Authors: Wen‐Cheng Chao, Wen‐Ting Liao, Jing‐Rong Wang, Hsiao‐Ni Sung, Hsin‐Hua Chen, Fang‐Ping Lin, Jou‐Yu Huang, Kuan‐Ting Liu, Tai‐Ming Ko

Source: Clinical and Translational Allergy, Vol 12, Iss 5, Pp n/a-n/a (2022)

Subject Terms: immunology, immunotherapy, insect hypersensitivity, molecular allergy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7022

Access URL: https://doaj.org/article/3192cf82eed04804852078c3fefaab99

Using RNA-Seq to Investigate Immune-Metabolism Features in Immunocompromised Patients With Sepsis

Authors: Po-Liang Cheng, Hsin-Hua Chen, Yu-Han Jiang, Tzu-Hung Hsiao, Chen-Yu Wang, Chieh-Liang Wu, Tai-Ming Ko, Wen-Cheng Chao

Source: Frontiers in Medicine, Vol 8 (2021)

Subject Terms: RNA-Seq, sepsis, immunocompromised, immune, metabolism, pathway analyses, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.747263/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/f0ad154fa56841ac9aab6b81aa33f467

A Novel Quality-Control Procedure to Improve the Accuracy of Rare Variant Calling in SNP Arrays

Authors: Ting-Hsuan Sun, Yu-Hsuan Joni Shao, Chien-Lin Mao, Miao-Neng Hung, Yi-Yun Lo, Tai-Ming Ko, Tzu-Hung Hsiao

Source: Frontiers in Genetics, Vol 12 (2021)

Subject Terms: SNP array, rare variant, quality-control, genotyping, disease screening, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2021.736390/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/37f20a450df540e9a5d03ef9a6d34080

Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19.

Authors: Cheng-Pu Sun, Jia-Tsrong Jan, I-Hsuan Wang, Hsiu-Hua Ma, Hui-Ying Ko, Ping-Yi Wu, Tzu-Jiun Kuo, Hsin-Ni Liao, Yu-Hua Lan, Zong-Lin Sie, Yen-Hui Chen, Yi-An Ko, Chun-Che Liao, Liang-Yu Chen, I-Jung Lee, Szu-I Tsung, Yun-Ju Lai, Ming-Tsai Chiang, Jian-Jong Liang, Wen-Chun Liu, Jing-Rong Wang, Joyce Pei-Yi Yuan, Yin-Shiou Lin, Yi-Ching Tsai, Shie-Liang Hsieh, Chia-Wei Li, Han-Chung Wu, Tai-Ming Ko, Yi-Ling Lin, Mi-Hua Tao

Source: PLoS Pathogens, Vol 17, Iss 8, p e1009758 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/4c7d04f4f9e34a85ac0d0588129271b2

SVAD: A genetic database curates non-ischemic sudden cardiac death-associated variants.

Authors: Wei-Chih Huang, Hsin-Tzu Huang, Po-Yuan Chen, Wei-Chi Wang, Tai-Ming Ko, Sirjana Shrestha, Chi-Dung Yang, Chun-San Tai, Men-Yee Chiew, Yu-Pao Chou, Yu-Feng Hu, Hsien-Da Huang

Source: PLoS ONE, Vol 15, Iss 8, p e0237731 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f8e6915918944b94923fcb00d633cf38

Identification of PTCSC3 as a Novel Locus for Large‐Vessel Ischemic Stroke: A Genome‐Wide Association Study

Authors: Tsong‐Hai Lee, Tai‐Ming Ko, Chien‐Hsiun Chen, Ming‐Ta Michael Lee, Yeu‐Jhy Chang, Chien‐Hung Chang, Kuo‐Lun Huang, Ting‐Yu Chang, Jiann‐Der Lee, Ku‐Chou Chang, Jen‐Tsung Yang, Ming‐Shien Wen, Chao‐Yung Wang, Ying‐Ting Chen, Chia‐San Hsieh, Shu‐Yu Chou, Yi‐Min Liu, Hui‐Wen Chen, Hung‐Ting Liao, Chia‐Wen Wang, Shih‐Ping Chen, Liang‐Suei Lu, Yuan‐Tsong Chen, Jer‐Yuarn Wu

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 3 (2016)

Subject Terms: atherosclerosis, genome‐wide association study, non‐coding RNA, polymorphism, stroke, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/3e5a386190bb4426a001168d3574604b

Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility.

Authors: Chia-Jung Chang, Ho-Chang Kuo, Jeng-Sheng Chang, Jong-Keuk Lee, Fuu-Jen Tsai, Chiea Chuen Khor, Li-Ching Chang, Shih-Ping Chen, Tai-Ming Ko, Yi-Min Liu, Ying-Ju Chen, Young Mi Hong, Gi Young Jang, Martin L Hibberd, Taco Kuijpers, David Burgner, Michael Levin, Jane C Burns, Sonia Davila, International Kawasaki Disease Genetics Consortium, Korean Kawasaki Disease Genetics Consortium, Taiwan Kawasaki Disease Genetics Consortium, Yuan-Tsong Chen, Chien-Hsiun Chen, Jer-Yuarn Wu, Yi-Ching Lee

Source: PLoS ONE, Vol 8, Iss 8, p e72037 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24023612/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f785e0ce8cb442d28b33506526470cec

Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers.

Authors: Beltran, Jan Vincent B., Fang-Ping Lin, Chaw-Liang Chang, Tai-Ming Ko

Source: Circulation; 11/28/2023, Vol. 148 Issue 22, p1778-1796, 19p

CXCL10/IP-10 Is a Biomarker and Mediator for Kawasaki Disease.

Authors: Tai-Ming Ko, Ho-Chang Kuo, Jeng-Sheng Chang, Shih-Ping Chen, Yi-Min Liu, Hui-Wen Chen, Fuu-Jen Tsai, Yi-Ching Lee, Chien-Hsiun Chen, Jer-Yuarn Wu, Yuan-Tsong Chen

Source: Circulation Research; 2/27/2015, Vol. 116 Issue 5, p876-883, 8p

Galectin-3 aggravates microglial activation and tau transmission in tauopathy.

Authors: Jian Jing Siew, Hui-Mei Chen, Feng-Lan Chiu, Chia-Wei Lee, Yao-Ming Chang, Hung-Lin Chen, Thi Ngoc Anh Nguyen, Hung-Ting Liao, Mengyu Liu, Hsiao-Tien Hagar, Yung-Chen Sun, Hsing-Lin Lai, Min-Hao Kuo, Blum, David, Luc Buée, Lee-Way Jin, Shih-Yu Chen, Tai-Ming Ko, Jie-Rong Huang, Hung-Chih Kuo

Source: Journal of Clinical Investigation. 1/16/2024, Vol. 134 Issue 2, p1-16. 16p.

Subjects: TAUOPATHIES, AMYLOID plaque, TAU proteins, INDUCED pluripotent stem cells, GALECTINS, ALZHEIMER'S disease, MICROGLIA

T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction.

Authors: Tai-Ming Ko, Yuan-Tsong Chen

Source: Expert Review of Clinical Immunology; Jul2012, Vol. 8 Issue 5, p467-477, 11p

Subject Terms: T cell receptors, CARBAMAZEPINE, STEVENS-Johnson Syndrome, DRUG side effects, TOXIC epidermal necrolysis, ALLERGIES

Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study.

Authors: Tai-Ming Ko, Chang-Youh Tsai, Shih-Yang Chen, Kuo-Shu Chen, Kuang-Hui Yu, Chih-Sheng Chu, Chung-Ming Huang, Chrong-Reen Wang, Chia-Tse Weng, Chia-Li Yu, Song-Chou Hsieh, Jer-Chia Tsai, Wen-Ter Lai, Wen-Chan Tsai, Guang-Dar Yin, Tsan-Teng Ou, Kai-Hung Cheng, Jeng-Hsien Yen, Teh-Ling Liou, Tsung-Hsien Lin

Source: BMJ: British Medical Journal. 10/3/2015, Vol. 351 Issue 8027, ph4848-h4848. 1p. 1 Chart.

Subject Terms: *PREVENTION of drug side effects, *DRUG eruptions, *ALLOPURINOL, *GENOTYPES

Geographic Terms: TAIWAN

797. Long-Term Inhibition of Hepatitis B Virus in Transgenic Mice by Adeno-Associated Virus- Delivered Short Hairpin RNA.

Authors: Chun-Chi Chen^1,2, Tai-Ming Ko^1,2, Ma, Hsin-I.³, Hui-Lin Wu⁴, Xiao Xiao⁵, Mi-Hua Tao¹

Source: Molecular Therapy. Jun2006, Vol. 13, pS309-S309. 1p.

Subject Terms: *LABORATORY mice, *LIVER diseases, *BILIARY tract, *TRANSGENIC mice, *HEPATITIS B virus, *GENE therapy