Discovery of a new hydrazone-oxamide hybrid capable of inducing necroptotic cell death in triple negative breast cancer cells

Authors: Akhavan, Romina ^{a, b}, Jabari Harsini, Sanaz ^{a, 1}, Shafiee, Samira ^{c, d, 1}, Eftekhari, Mahya ^{a, 1}, Tahmasvand, Raheleh ^b, Taghipour, Fereshteh ^b, Kooshafar, Zahra ^b, Mohammadmirzaeizarandi, Hiva ^{a, b}, Salimi, Misha ^e, Almasirad, Ali ^{a, ⁎}, Salimi, Mona ^{b, ⁎}

Source: In Bioorganic Chemistry April 2025 157

Design and synthesis of novel 4-thiazolidinone derivatives with promising anti-breast cancer activity: Synthesis, characterization, in vitro and in vivo results

Authors: Tahmasvand, Raheleh, Bayat, Peyman, Vahdaniparast, Seyyed Mahmood, Dehghani, Soudeh, Kooshafar, Zahra, Khaleghi, Sepideh, Almasirad, Ali, Salimi, Mona

Source: In Bioorganic Chemistry November 2020 104

Synthesis of oxamide-hydrazone hybrid derivatives as potential anticancer agents.

Authors: Dehbid, Mina¹ (AUTHOR), Tahmasvand, Raheleh² (AUTHOR), Tasharofi, Marzieh³ (AUTHOR), Shojaie, Fatemeh⁴ (AUTHOR), Aghamaali, Mahmoudreza¹ (AUTHOR), Almasirad, Ali³ (AUTHOR), Salimi, Mona² (AUTHOR)

Source: Research in Pharmaceutical Sciences. Feb2023, Vol. 18 Issue 1, p24-38. 15p.

Subject Terms: *HYDRAZONE derivatives, *TRIPLE-negative breast cancer, *ANTINEOPLASTIC agents, *CELL cycle, *MASS spectrometry, *CHEMICAL synthesis

In vitro and in vivo activity of a novel oxamide-hydrazone hybrid derivative against triple-negative breast cancer.

Authors: Tahmasvand, Raheleh, Dehghani, Soudeh, Kooshafar, Zahra, Emami Najafi, Seyedeh Azadeh, Almasirad, Ali, Salimi, Mona

Source: Naunyn-Schmiedeberg's Archives of Pharmacology; Jul2024, Vol. 397 Issue 7, p5119-5129, 11p

Subject Terms: TRIPLE-negative breast cancer, HEMATOXYLIN & eosin staining, STAINS & staining (Microscopy), WESTERN immunoblotting, CELL death, HORMONE receptor positive breast cancer

Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity.

Authors: Koopaei, Nasrin Nassiri, Shademani, Mehrasa, Yazdi, Nasrin Shirzad, Tahmasvand, Raheleh, Dehbid, Mina, Koopaei, Mansur Nassiri, Azizian, Homa, Mousavi, Zahra, Almasirad, Ali, Salimi, Mona

Source: BMC Chemistry; 11/1/2022, Vol. 16 Issue 1, p1-15, 15p

Subject Terms: HYDRAZONE derivatives, ANTINEOPLASTIC agents, T helper cells, WESTERN immunoblotting, HEPATOCELLULAR carcinoma, STAINS & staining (Microscopy)

Two novel anticancer compounds with minimum cardiotoxic property.

Authors: Afsharirad, Tayebeh, Tahmasvand, Raheleh, Amini, Mohsen, Daraei, Bahram, Salimi, Mona

Source: BMC Pharmacology & Toxicology; 11/19/2020, Vol. 21 Issue 1, p1-8, 8p

Subject Terms: CANCER cell proliferation, CELL death, MEMBRANE potential, MITOCHONDRIAL membranes, PROPIDIUM iodide

Two Novel Compounds with Tri-aryl Structures as Effective Anti-Breast Cancer Candidates In-vivo.

Authors: Afsharinasab, Ahoo, Moayer, Fariborz, Amini, Mohsen, Choopani, Samira, Tahmasvand, Raheleh, dehghani, Soudeh, Mousavi, Seyede Zahra, Salimi, Mona

Source: Iranian Journal of Pharmaceutical Research; Spring2020, Vol. 19 Issue 2, p145-152, 8p

Subject Terms: METASTATIC breast cancer, BREAST cancer prognosis, LUNG cancer, TUMOR growth, BREAST tumors

A novel hydrazide compound exerts anti-metastatic effect against breast cancer

Authors: Dehghani, Soudeh, Kooshafar, Zahra, Almasirad, Ali, Tahmasvand, Raheleh, Moayer, Fariborz, Muhammadnejad, Ahad, Shafiee, Samira, Salimi, Mona

Source: Biological Research; December 2019, Vol. 52 Issue: 1 p1-8, 8p

Potent antitumor property of Allium bakhtiaricum extracts.

Authors: Vafaee, Kosar, Dehghani, Soudeh, Tahmasvand, Raheleh, Saeed Abadi, Farzaneh, Irian, Saeed, Salimi, Mona

Source: BMC Complementary & Alternative Medicine; 6/4/2019, Vol. 19 Issue 1, pN.PAG-N.PAG, 1p, 4 Diagrams, 2 Charts, 1 Graph

Subject Terms: ACETIC acid, ANIMAL experimentation, BIOLOGICAL assay, BREAST tumors, CELL cycle, CELL death, CELL differentiation, CELL lines, DRUG design, CLINICAL drug trials, FLOW cytometry, HYDROCARBONS, LUNGS, METASTASIS, MICE, MICROSCOPY, STAINS & staining (Microscopy), TRADITIONAL medicine, VEGETABLES, WESTERN immunoblotting, PLANT extracts, IN vitro studies, IN vivo studies

Geographic Terms: IRAN