TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment

Authors: Fonseca, Danae ^{1, 2}, Pisanelli, Giuseppe ^{1, 2, 3}, Seoane, Rocío ^{1, 2}, Miorin, Lisa ^{1, 2, ∗}, García-Sastre, Adolfo ^{1, 2, 4, 5, 6, 7, 8, ∗∗}

Source: In Cell Reports 24 December 2024 43(12)

TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates Metabolic and Immune Advantages in Hepatocellular Carcinoma

Authors: Zhixuan Bian, Chang Xu, Xiaoying Wang, Baohua Zhang, Yixuan Xiao, Li Liu, Shasha Zhao, Nan Huang, Fengjiao Yang, Yue Zhang, Shaobo Xue, Xiongjun Wang, Qiuhui Pan, Fenyong Sun

Source: Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)

Subject Terms: hepatocellular carcinoma, immune evasion, palmitic acid, TRIM65, uracil metabolism, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/b7d59aeaa7b14385b59bd5a0fd13d6d2

Supplementary kumatakenin prevents esophagus cancer progression by blocking TRIM65-FASN axis-mediated metabolic reprogramming

Authors: Tingting Zhang, Zhengqiang Yang, Xu Li, Linke Yang, Qixi Yu, Fengxiang Li, Xin Sun

Source: Journal of Functional Foods, Vol 117, Iss , Pp 106223- (2024)

Subject Terms: Kumatakenin, TRIM65, FASN, Esophageal cancer, Ubiquitination, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464624002251; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/1431906234e549b6b4e145acdf3996eb

Tripartite Motif-Containing Protein 65 (TRIM65) Inhibits Hepatitis B Virus Transcription

Authors: Sheng Shen, Ran Yan, Zhanglian Xie, Xiaoyang Yu, Hongyan Liang, Qiuhong You, Hu Zhang, Jinlin Hou, Xiaoyong Zhang, Yuanjie Liu, Jian Sun, Haitao Guo

Source: Viruses, Vol 16, Iss 6, p 890 (2024)

Subject Terms: HBV, tripartite motif proteins, TRIM65, HNF4α, transcription, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/6/890; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/256b3eafdc7d4d658498365159f415d5

TRIM65 Promotes Cervical Cancer Through Selectively Degrading p53-Mediated Inhibition of Autophagy and Apoptosis

Authors: Xiao-Yu Wang, Hai-Wei Mao, Xiao-Hui Guan, Qi-Ming Huang, Zhen-Ping Yu, Jie Wu, Hui-Lan Tan, Feng Zhang, Xuan Huang, Ke-Yu Deng, Hong-Bo Xin

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: TRIM65, ubiquitination, autophagy, apoptosis, cervical cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.853935/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/6ac5992793624cb7a5719b367c173141

The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3

Authors: Tiantian Tang, Ping Li, Xinhui Zhou, Rui Wang, Xiuqin Fan, Mengyi Yang, Kemin Qi

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: NLRP3 inflammasome, TRIM65, ubiquitination, posttranslational regulation, inflammasome-driven diseases, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.741839/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/181fbb101e504d7f9f7a3b7a704f7d69

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