Ferroptosis emerges as the predominant form of regulated cell death in goat sperm cryopreservation.

Authors: Hai, Erhan¹ (AUTHOR), Li, Boyuan¹ (AUTHOR), Song, Yukun¹ (AUTHOR), Zhang, Jian¹ (AUTHOR), Zhang, Jiaxin¹ (AUTHOR) zjxcau@163.com

Source: Journal of Animal Science & Biotechnology. 2025, Vol. 16 Issue 1, p1-17. 17p.

Subject Terms: *TRANSFERRIN receptors, *CELL death, *CYTOLOGY, *PROTEIN receptors, *LIFE sciences, *SPERMATOZOA

A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro.

Authors: Petersen, Inga¹ (AUTHOR) inga.petersen@uu.se, Morrison, Jamie I.¹ (AUTHOR), Petrovic, Alex¹ (AUTHOR), Babic, Neira¹ (AUTHOR), Metzendorf, Nicole G.¹ (AUTHOR), Godec, Ana¹ (AUTHOR), de la Rosa, Andrés¹ (AUTHOR), Rofo, Fadi¹ (AUTHOR), Bondza, Sina^2,3 (AUTHOR), Buijs, Jos^2,3 (AUTHOR), Ranjbarian, Farahnaz⁴ (AUTHOR), Hofer, Anders⁴ (AUTHOR), Sehlin, Dag⁵ (AUTHOR), Hultqvist, Greta¹ (AUTHOR) greta.hultqvist@uu.se

Source: Scientific Reports. 12/23/2024, Vol. 14 Issue 1, p1-12. 12p.

Subject Terms: *TRANSFERRIN receptors, *TRANSCYTOSIS, *BRAIN diseases, *THERAPEUTICS, *ENDOTHELIAL cells, *BLOOD-brain barrier, *BISPECIFIC antibodies

Orostachys japonica Induces Ferroptosis in 5-Fluorouracil-Resistantance Acquired SNU-C5 Colorectal Cancer Cells.

Alternate Title: Orostachys japonica Induce Ferroptosis en Células de Cáncer Colorrectal SNU-C5 Resistentes al 5-Fluorouracilo.

Authors: Sang-Pil Yoon¹ spyoon@jejunu.ac.kr

Source: International Journal of Morphology. 2024, Vol. 42 Issue 6, p1508-1516. 9p.

Subject Terms: *DRUG resistance in cancer cells, *TRANSFERRIN receptors, *CELL cycle, *COLORECTAL cancer, *CELL death

Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries.

Authors: Holst, Mikkel Roland¹ (AUTHOR), Richner, Mette¹ (AUTHOR), Arenshøj, Pernille Olsgaard¹ (AUTHOR), Alam, Parvez^1,2 (AUTHOR), Hyldig, Kathrine^1,3 (AUTHOR), Nielsen, Morten Schallburg¹ (AUTHOR) mn@biomed.au.dk

Source: Fluids & Barriers of the CNS. 10/14/2024, Vol. 21 Issue 1, p1-11. 11p.

Subject Terms: *TRANSFERRIN receptors, *EXPANSION microscopy, *BLOOD-brain barrier, *ENDOTHELIAL cells, *BRAIN diseases

Soluble transferrin receptor and soluble transferrin receptor/log ferritin index in coronavirus disease 2019.

Authors: Abdalla, Abdalla E.¹ (AUTHOR) abdallaessam94@gmail.com, Doha, Saad A.¹ (AUTHOR), Nashaat, Soliman M.² (AUTHOR), Alaa El-Din, Abdel-Hamid S.¹ (AUTHOR), Mohammed, Saad A.³ (AUTHOR), Hebat-Allah, Nashaat H.¹ (AUTHOR)

Source: Egyptian Journal of Haematology. Oct-Dec2024, Vol. 49 Issue 4, p405-413. 9p.

Subject Terms: *IRON in the body, *TRANSFERRIN receptors, *COVID-19, *FERRITIN, *HEPCIDIN

CD71 expressing circulating neutrophils serve as a novel prognostic biomarker for metastatic spread and reduced outcome in pancreatic ductal adenocarcinoma patients.

Authors: Hansen, Frederik J.¹ (AUTHOR), Mittelstädt, Anke¹ (AUTHOR), Clausen, Finn-Niklas¹ (AUTHOR), Knoedler, Samuel² (AUTHOR), Knoedler, Leonard³ (AUTHOR), Klöckner, Sebastian¹ (AUTHOR), Kuchenreuther, Isabelle¹ (AUTHOR), Mazurie, Johanne¹ (AUTHOR), Arnold, Lisa-Sophie¹ (AUTHOR), Anthuber, Anna¹ (AUTHOR), Jacobsen, Anne¹ (AUTHOR), Merkel, Susanne¹ (AUTHOR), Weisel, Nadine¹ (AUTHOR), Klösch, Bettina¹ (AUTHOR), Karabiber, Alara¹ (AUTHOR), Tacyildiz, Irem¹ (AUTHOR), Czubayko, Franziska¹ (AUTHOR), Reitberger, Helena¹ (AUTHOR), Gendy, Amr El¹ (AUTHOR), Brunner, Maximilian¹ (AUTHOR)

Source: Scientific Reports. 9/10/2024, Vol. 14 Issue 1, p1-14. 14p.

Subject Terms: *TRANSFERRIN receptors, *PANCREATIC duct, *CLINICAL medicine, *CANCER invasiveness, *NEUTROPHILS, *TRANSFERRIN

SGLT2 inhibition mitigates transition from acute kidney injury to chronic kidney disease by suppressing ferroptosis.

Authors: Hirashima, Yutaro¹, Nakano, Toshiaki¹ nakano.toshiaki.455@m.kyushu-u.ac.jp, Torisu, Kumiko^1,2, Aihara, Seishi¹, Wakisaka, Masanori³, Kitazono, Takanari¹

Source: Scientific Reports. 9/2/2024, Vol. 14 Issue 1, p1-17. 17p.

Subject Terms: *NUCLEAR factor E2 related factor, *TRANSFERRIN receptors, *GLUTATHIONE peroxidase, *ACUTE kidney failure, *CHRONIC kidney failure, *CARNITINE palmitoyltransferase, *KIDNEY tubules

Effect of ferric citrate on hippocampal iron accumulation and widespread molecular alterations associated with cognitive disorder in an ovariectomized mice model.

Authors: Cui, Lingling¹ (AUTHOR), Zhou, Huijun¹ (AUTHOR), Hao, Yudan¹ (AUTHOR), Yang, Xiaoli¹ (AUTHOR), Li, Zhiqian¹ (AUTHOR), Gao, Yuting¹ (AUTHOR), Zhang, Zhengya¹ (AUTHOR), Ren, Lina¹ (AUTHOR), Ji, Linpu¹ (AUTHOR), Sun, Ruijie¹ (AUTHOR), Wang, Yibo¹ (AUTHOR), Wang, Xian¹ (AUTHOR) wangxian@zzu.edu.cn

Source: CNS Neuroscience & Therapeutics. Sep2024, Vol. 30 Issue 9, p1-14. 14p.

Subject Terms: *IRON in the body, *TRANSFERRIN receptors, *IRON proteins, *TRANSMISSION electron microscopy, *IMAGE transmission

Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin.

Authors: Duncan, Samuel M.¹ (AUTHOR), Carbajo, Carla Gilabert² (AUTHOR), Nagar, Rupa¹ (AUTHOR), Zhong, Qi² (AUTHOR), Breen, Conor³ (AUTHOR), Ferguson, Michael A. J.¹ (AUTHOR) m.a.j.ferguson@dundee.ac.uk, Tiengwe, Calvin² (AUTHOR) m.a.j.ferguson@dundee.ac.uk

Source: PLoS Pathogens. 6/27/2024, Vol. 20 Issue 6, p1-28. 28p.

Subject Terms: *TRANSFERRIN, *TRANSFERRIN receptors, *TRYPANOSOMA brucei, *ENDOCYTOSIS, *GLYCOPROTEINS, *PROTEIN stability, *CARBOHYDRATES

Fucoxanthin Induces Ferroptosis in Cancer Cells via Downregulation of the Nrf2/HO−1/GPX4 Pathway.

Authors: Du, Hao-Fei¹ (AUTHOR), Wu, Jia-Wei¹ (AUTHOR), Zhu, Yu-Shan¹ (AUTHOR) youzanzizwu@163.com, Hua, Zheng-Hao¹ (AUTHOR), Jin, Si-Zhou¹ (AUTHOR), Ji, Jin-Chao¹ (AUTHOR), Wang, Cai-Sheng¹ (AUTHOR), Qian, Guo-Ying¹ (AUTHOR), Jin, Xu-Dong¹ (AUTHOR) jinxudong@zwu.edu.cn, Ding, Hao-Miao¹ (AUTHOR) jinxudong@zwu.edu.cn

Source: Molecules. Jun2024, Vol. 29 Issue 12, p2832. 15p.

Subject Terms: *NUCLEAR factor E2 related factor, *TRANSFERRIN receptors, *GLUTATHIONE peroxidase, *P53 antioncogene, *ERYTHROCYTE membranes, *HEME oxygenase, *CANCER cells

Effect of IL-1β on the Development of Spermatogenesis In Vitro in Normal and Busulfan-Treated Immature Mice.

Authors: Ali, Nagham^1,2,3 (AUTHOR) nagham902@gmail.com, Lunenfeld, Eitan⁴ (AUTHOR) eitanlun@ariel.ac.il, Huleihel, Mahmoud^1,2,3 (AUTHOR) huleihel@bgu.ac.il

Source: International Journal of Molecular Sciences. May2024, Vol. 25 Issue 9, p4926. 16p.

Subject Terms: *TRANSFERRIN receptors, *SPERMATOGENESIS, *ANDROGEN receptors, *ANDROGEN-binding proteins, *SERTOLI cells, *LEYDIG cells, *CELL culture

Association of poly(rC)-binding protein-2 with sideroflexin-3 through TOM20 as an iron entry pathway to mitochondria.

Authors: Mi, Danyang¹ (AUTHOR), Yanatori, Izumi^1,2 (AUTHOR), Zheng, Hao¹ (AUTHOR), Kong, Yingyi¹ (AUTHOR), Hirayama, Tasuku³ (AUTHOR), Toyokuni, Shinya^1,4,5 (AUTHOR) toyokuni@med.nagoya-u.ac.jp

Source: Free Radical Research. Mar/Apr2024, Vol. 58 Issue 4, p261-275. 15p.

Subject Terms: *TRANSFERRIN, *TRANSFERRIN receptors, *CHRONIC myeloid leukemia, *FERRITIN, *MITOCHONDRIA, *MITOCHONDRIAL proteins, *STIMULATED emission, *IRON overload

Mechanism of Ziyuglycoside II-mediated Ferroptosis-related Proteins on the Proliferation and Metastasis of Human Lung Adenocarcinoma Cell Lines.

Authors: Zhang, Jian-hui¹ (AUTHOR), Xie, Li-jun² (AUTHOR), Wang, Han-lu¹ (AUTHOR), Chen, Hui¹ (AUTHOR), Meng, Xiao-rong^1,3 (AUTHOR), Lin, Xing^1,4 (AUTHOR), Lin, Xin-fu^1,5 (AUTHOR), Liao, Li-sheng^1,6 (AUTHOR), Chen, Ting¹ (AUTHOR), Luo, Jie-Wei^1,3 (AUTHOR) docluo0421@aliyun.com, Hong, Lu-yu² (AUTHOR), Chen, Xin^1,7 (AUTHOR)

Source: Pharmacognosy Magazine. Mar2024, Vol. 20 Issue 1, p7-15. 9p.

Subject Terms: *TRANSFERRIN receptors, *CELL lines, *CANCER cell growth, *GLUTAMATE transporters, *CELL migration

A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense.

Authors: Silvester, Eleanor¹ (AUTHOR), Szoor, Balazs¹ (AUTHOR), Ivens, Alasdair¹ (AUTHOR), Awuah-Mensah, Georgina² (AUTHOR), Gadelha, Catarina² (AUTHOR), Wickstead, Bill² (AUTHOR), Matthews, Keith R.¹ (AUTHOR) keith.matthews@ed.ac.uk

Source: PLoS Pathogens. 2/26/2024, Vol. 20 Issue 2, p1-21. 21p.

Subject Terms: *TRANSFERRIN receptors, *RNA interference, *TRYPANOSOMA, *SMALL interfering RNA, *LIFE cycles (Biology), *BLOOD parasites

Geographic Terms: SUB-Saharan Africa

IST1 regulates select recycling pathways.

Authors: Clippinger, Amy K.¹ (AUTHOR), Naismith, Teresa V.¹ (AUTHOR), Yoo, Wonjin² (AUTHOR), Jansen, Silvia¹ (AUTHOR), Kast, David J.¹ (AUTHOR), Hanson, Phyllis I.^1,2 (AUTHOR) pihanson@umich.edu

Source: Traffic. Jan2024, Vol. 25 Issue 1, p1-20. 20p.

Subject Terms: *TRANSFERRIN receptors, *ENDOSOMES, *CELL membranes, *CLATHRIN, *MEMBRANE proteins, *MANNOSE

An investigation of the distributions of ferroptosis and necroptosis mediators in the maternal–fetal interface at different days of rat pregnancy.

Authors: Tatar, Musa¹ (AUTHOR) mtatar@kastamonu.edu.tr, Tüfekci, Kıymet Kübra² (AUTHOR)

Source: Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C. Jan2024, Vol. 53 Issue 1, p1-13. 13p.

Subject Terms: *TRANSFERRIN receptors, *TRANSFERRIN, *DECIDUA, *YOLK sac, *PREGNANCY, *RATS, *LABORATORY rats, *PROTEIN expression

Transferrin receptor levels and its rare variant are associated with human obesity.

Authors: Qiu, Jin¹ (AUTHOR), Zhang, Zhiyin² (AUTHOR), Hu, Yepeng³ (AUTHOR), Guo, Yuhan¹ (AUTHOR), Liu, Caizhi¹ (AUTHOR), Chen, Yanru² (AUTHOR), Wang, Dongmei¹ (AUTHOR), Su, Junlei² (AUTHOR), Wang, Sainan¹ (AUTHOR), Ni, Mengshan² (AUTHOR), Xu, Sainan¹ (AUTHOR), Yu, Jian¹ (AUTHOR), Hu, Tianhui¹ (AUTHOR), Song, Gaojie¹ (AUTHOR), Ma, Xinran¹ (AUTHOR), Gu, Xuejiang³ (AUTHOR) guxuejiang@wmu.edu.cn, Wang, Jiqiu² (AUTHOR) wangjq@shsmu.edu.cn, Xu, Lingyan¹ (AUTHOR) lyxu@bio.ecnu.edu.cn

Source: Journal of Diabetes. Jan2024, Vol. 16 Issue 1, p1-11. 11p.

Subject Terms: *TRANSFERRIN receptors, *OBESITY, *IRON in the body, *BROWN adipose tissue, *BODY mass index, *ADIPOSE tissue diseases

Activation of Ferroptosis and NF-κB/NLRP3/MAPK Pathways in Methylmercury-Induced Hepatotoxicity.

Authors: Xie, Yueqing¹ (AUTHOR), Yu, Hongsen¹ (AUTHOR), Ye, Yingrong¹ (AUTHOR), Wang, Jingjing¹ (AUTHOR), Yang, Zhengtao¹ (AUTHOR), Zhou, Ershun¹ (AUTHOR) zhouershun@fosu.edu.cn

Source: Toxicology & Industrial Health. Mar2025, Vol. 41 Issue 3, p131-139. 9p.

Subject Terms: *TRANSFERRIN receptors, *BIOMARKERS, *LIVER injuries, *CELLULAR signal transduction, *GLUTAMATE transporters, *TRANSFERRIN

Transferrin receptor uptakes iron from tumor-associated neutrophils to regulate invasion patterns of OSCC.

Authors: Si, Qian^1,2 (AUTHOR), Wang, Yuhan^1,3 (AUTHOR), Lu, Wanqiu⁴ (AUTHOR), Liu, Zijian^1,3 (AUTHOR), Song, Yuxian¹ (AUTHOR), Chen, Sheng² (AUTHOR), Xia, Shu² (AUTHOR), Li, Huiling² (AUTHOR), Weng, Pei¹ (AUTHOR), Jing, Yue¹ (AUTHOR), Yu, Qiuya¹ (AUTHOR), Zhu, Feng³ (AUTHOR) drzf@nju.edu.cn, Zhang, Xiaoxin¹ (AUTHOR) 693216371@qq.com, Huang, Xiaofeng² (AUTHOR) hxf681008@sina.com, Ni, Yanhong¹ (AUTHOR) Yanhong.Ni@nju.edu.cn

Source: Cancer Immunology, Immunotherapy. Feb2025, Vol. 74 Issue 2, p1-18. 18p.

Subject Terms: *TRANSFERRIN receptors, *CANCER cell migration, *CELL migration, *SQUAMOUS cell carcinoma, *IRON metabolism

Iron promotes isocitrate dehydrogenase mutant glioma cell motility.

Authors: Owusu, Stephenson Boakye¹ (AUTHOR), Russell, Emily¹ (AUTHOR), Ekanayake, Akalanka B.² (AUTHOR), Tivanski, Alexei V.² (AUTHOR), Petronek, Michael S.¹ (AUTHOR) michael-petronek@uiowa.edu

Source: Free Radical Biology & Medicine. Jan2025, Vol. 226, p109-116. 8p.

Subject Terms: *ISOCITRATE dehydrogenase, *TRANSFERRIN receptors, *IRON metabolism, *AMMONIUM sulfate, *CELL motility