An Automated Pipeline for Tumour-Infiltrating Lymphocyte Scoring in Breast Cancer

Authors: Shephard, Adam J, Jahanifar, Mostafa, Wang, Ruoyu, Dawood, Muhammad, Graham, Simon, Sidlauskas, Kastytis, Khurram, Syed Ali, Rajpoot, Nasir M, Raza, Shan E Ahmed

Source: 2024 IEEE International Symposium on Biomedical Imaging (ISBI) Biomedical Imaging (ISBI), 2024 IEEE International Symposium on. :1-5 May, 2024

Relation: 2024 IEEE International Symposium on Biomedical Imaging (ISBI)

An Optimized 3D Tile Scheduling Method Adapted to Terminal's GPU DRAM

Authors: Shang, Xiaoyun, Jia, Qingren, Huang, Yazhe, Yang, Quan, Chen, Juan

Source: 2023 5th International Conference on Geoscience and Remote Sensing Mapping (GRSM) Geoscience and Remote Sensing Mapping (GRSM), 2023 5th International Conference on. :111-115 Oct, 2023

Relation: 2023 5th International Conference on Geoscience and Remote Sensing Mapping (GRSM)

Characterizing the Survival-Associated Interactions Between Tumor-Infiltrating Lymphocytes and Tumors From Pathological Images and Multi-Omics Data

Authors: Shao, W., Zuo, Y., Shi, Y., Wu, Y., Tang, J., Zhao, J., Sun, L., Lu, Z., Sheng, J., Zhu, Q., Zhang, D.

Source: IEEE Transactions on Medical Imaging IEEE Trans. Med. Imaging Medical Imaging, IEEE Transactions on. 42(10):3025-3035 Oct, 2023

Leukocyte-specific protein 1 is associated with the stage and tumor immune infiltration of cervical cancer

Authors: Dianqin Xu, Xinzhu Zhou, Shaoju Min, Yu Zhang, Xiaoyu Zhu, Kun Qiao, Luhong Xie, Ji Ren, Yameng Liu, Ziwen Xiao, Yujie Tan

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-14 (2025)

Subject Terms: Cervical cancer, HPV16, Leucocyte-specific protein 1 (LSP1), Tumour infiltrating lymphocytes (TILs), Tumour microenvironment (TME), Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/76f8b31b2a6a47ddb90b6dff3f42b5d4

Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers

Authors: Feng Hao, Zhang Yan, Luo Shen, Wang Hui, Qiu Ling, Yang Xiaoyu, Jiang Hua

Source: Journal of Ovarian Research, Vol 18, Iss 1, Pp 1-19 (2025)

Subject Terms: FLT3, PI3K/AKT pathway, Tumor-infiltrating lymphocytes (TILs), Ovarian cancer, Cervical cancer, Spatial transcriptomics, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: https://doaj.org/toc/1757-2215

Access URL: https://doaj.org/article/3b2079b5ffa94a53a46d9b8a79eb2952

Psychometric analysis of the three item loneliness scale in the Czech Republic

Authors: Zdenek Meier, Lukas Novak, Jakub Helvich, Patrik Licka, Peter Tavel

Source: BMC Psychology, Vol 13, Iss 1, Pp 1-15 (2025)

Subject Terms: Loneliness, Measurement, TILS, Psychometric Properties, Validation, Item response theory, Psychology, BF1-990

File Description: electronic resource

Relation: https://doaj.org/toc/2050-7283

Access URL: https://doaj.org/article/ff96a23540ff4f988c91bc2aaae9d7c7

The predictive role of PD-L1 expression and CD8 + TIL levels in determining the neoadjuvant chemotherapy response in advanced ovarian cancer

Authors: T. Aliyeva, B. Y. Aktas, F. Gundogdu, E. Chalabiyev, Z. Arik, A. Usubutun

Source: Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-10 (2024)

Subject Terms: Ovarian cancer, Neoadjuvant chemotherapy, PD-L1, TILs, CRS, Gynecology and obstetrics, RG1-991

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Relation: https://doaj.org/toc/1757-2215

Access URL: https://doaj.org/article/cb0edd594830470db126313be3f9163e

On-treatment biopsies to predict response to neoadjuvant chemotherapy for breast cancer

Authors: Bruno Valentin Sinn, Katharina Sychra, Michael Untch, Thomas Karn, Marion van Mackelenbergh, Jens Huober, Wolfgang Schmitt, Frederik Marmé, Christian Schem, Christine Solbach, Elmar Stickeler, Hans Tesch, Peter A. Fasching, Andreas Schneeweiss, Volkmar Müller, Johannes Holtschmidt, Valentina Nekljudova, Sibylle Loibl, Carsten Denkert

Source: Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)

Subject Terms: Breast cancer, Neoadjuvant therapy, Serial biopsies, TILs, Ki-67, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1465-542X

Access URL: https://doaj.org/article/7254adee1eef456f91cca8c6f84490e2

Analysis of the lymphoid tumor microenvironment (TILs) in breast cancer by flow cytometry

Authors: T. N. Zabotina, A. A. Borunova, A. I. Сhertkova, I. B. Shoua, Z. G. Kadagidze

Source: Медицинская иммунология, Vol 26, Iss 4, Pp 819-826 (2024)

Subject Terms: flow cytometry, lymphocyte subpopulations, tumor microenvironment, tils, breast cancer, immunophenotype, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.mimmun.ru/mimmun/article/view/3055; https://doaj.org/toc/1563-0625; https://doaj.org/toc/2313-741X

Access URL: https://doaj.org/article/ac3ffd218ead4f0c9d7d3d308aaa5914

Updates on Breast Cancer

Contributors: Cassano, Enrico, Pesapane, Filippo

Subject Terms: ductal carcinoma in situ (DCIS), invasive breast carcinoma, breast, biopsy, overtreatment, active surveillance, Contrast-Enhanced Mammography (CEM), Dynamic Contrast Magnetic Resonance Imaging (DCE-MRI), radiomics, artificial intelligence, breast tumor segmentation, convolutional neural network, deep learning, X-ray images, breast cancer, brain metastasis, tissue-specific metastasis, organotropism, cancer metabolism, oxidative phosphorylation (OXPHOS), mitochondria, cyclooxygenase 7b (Cox7b), hereditary breast cancer, cancer susceptibility genes, PALB2, aberrant splicing, functional assay, minigenes, clinical interpretation, cyclin-dependent kinase inhibitor 4 and 6, HER2-low, palbociclib, circulating tumor cells, neoplastic cells, circulating, neoplasms/diagnosis, circulating/pathology, breast neoplasms/pathology, biomarkers, tumor, blood, liquid biopsy, AhR, agonist, ligand, TCDD, triple-negative breast cancer, exploratory subgroup discovery, chemoimmunotherapy, bone metastases, bone scan, follow-up, prognosis, survival, SETD7, molecular subtypes, gene expression, biological processes, HER2, antibody-drug conjugate, trastuzumab-deruxtecan, T-Dxd, communication, decision-making, patient empowerment, ONEST, observers needed to evaluate subjective tests, TILs, sTILs, tumour-infiltrating lymphocytes, triple-negative, reproducibility, international immuno-oncology biomarker working group, European Working Group for Breast Screening Pathology, breast-conserving surgery, radiation, de-escalation, early breast cancer, metastatic breast cancer, BRCA, NGS, HRD score, homologous recombination deficiency, mutational signature, PARPi, platinum salts, metastasis, secretome, immune modulation, tumor microenvironment, drug resistance, therapeutic targets, precision oncology, Medicine and Nursing, Diseases and disorders, Oncology

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/139330
https://mdpi.com/books/pdfview/book/9327

The inhibitory effects of nimotuzumab on CD276 expression and immune escape in head and neck squamous cell carcinoma: Insights into anticancer mechanisms

Authors: Hu, Minwan ^{a, b, c}, Tang, Borui ^{b, c}, Zhang, Di ^{b, c}, Wang, Xuhong ^{a, ⁎}, Zhao, Xiuli ^{b, c, ⁎}

Source: In International Immunopharmacology 6 February 2025 147

Tumor infiltrating lymphocytes (TILs) – Pathologia, quo vadis? – A global survey

Authors: Skok, Kristijan ^{a, b}, Bräutigam, Konstantin ^{c, ⁎}

Source: In Pathology - Research and Practice February 2025 266

Infections in Patients with Solid Tumors Undergoing Adoptive Cellular Therapy

Authors: Avutu, Viswatej ^{1, 2, ⁎}, Algazaq, Jumanah N. ^{3, †}, Seier, Kenneth ⁴, Desir-Camille, Rhoena ¹, Qin, Li-Xuan ⁴, Babatunde, Olayode ⁵, Adusumilli, Prasad S. ^{6, 7, 8}, Klebanoff, Christopher A. ^{2, 7, 9}, Kotecha, Ritesh R. ^{2, 7, 10}, Shoushtari, Alexander N. ^{2, 7, 11}, Slovin, Susan ^{2, 7, 10}, Warner, Allison Betof ^{2, 7, 11}, Park, Jae H. ^{2, 7, 12}, Schoenfeld, Adam J. ^{2, 7, 13}, O'Cearbhaill, Roisin ^{2, 7, 14}, D'Angelo, Sandra ^{1, 2, 7, #}, Seo, Susan K. ^{2, 3, #}

Source: In Transplantation and Cellular Therapy February 2025

Morpho-phenotypic characterization of melanoma brain metastases immune microenvironment: A multicentre retrospective study

Authors: Filippo Nozzoli, Marco Gessi, Filippo Ugolini, Sara Simi, Luca Tinunin, Luigi Francesco Iannone, Alice Esposito, Giovanni Muscas, Alessandro Della Puppa, Isabella Ciardetti, Nicola Pimpinelli, Vincenzo De Giorgi, Isacco Desideri, Lorenzo Livi, Laura Doni, Giovanni Schinzari, Ernesto Rossi, Mario Mandalà, Daniela Massi

Source: EJC Skin Cancer, Vol 2, Iss , Pp 100263- (2024)

Subject Terms: Melanoma, brain metastasis, tumour associated astrogliosis, tumour infiltrating lymphocytes (TILs), tumour associated macrophages (TAMs), tumor microenvironment (TME), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772611824002519; https://doaj.org/toc/2772-6118

Access URL: https://doaj.org/article/aaf276776272453cab39caebadf3f781

TIL Therapy in Lung Cancer: Current Progress and Perspectives

Authors: Weilei Hu, Yifei Bian, Hongbin Ji

Source: Advanced Science, Vol 11, Iss 46, Pp n/a-n/a (2024)

Subject Terms: Adoptive cell transfer (ACT), Lung cancer, Non‐small cell lung cancer (NSCLC), Tumor‐infiltrating lymphocytes (TILs), Tumor‐reactive T cells, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/1906cd43249c4b1199302ef5ae3f2c32

Clinical-scale, modular manufacturing of tumor-reactive TILs using a closed and automated culture system

Authors: Christina Völzke, Lisa Ehrhardt, Laura Fischer, Peter Maul, Carina Wenzel, Arina Riabinska, Elvira Criado-Moronati, Mike Dienstbier, Jessica Hassel, Danmei Zhang, John B. Haanen, Rupert Handgretinger, Ian R. Hardy, Bianca Heemskerk, Andrzej Dzionek

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: tumor reactive T cells, CD137, TILs, CliniMACS Prodigy, REP, GMP compliant cell manufacturing, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1483254/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/0c55473bf87947b58a151a1e92727b8e

The current socioeconomic and regulatory landscape of immune effector cell therapies

Authors: Chiranjeevi Sainatham, Devvrat Yadav, Aravind Dilli Babu, Jayanth Reddy Tallapalli, Sai Gautham Kanagala, Evgenii Filippov, Franco Murillo Chavez, Nausheen Ahmed, Forat Lutfi

Source: Frontiers in Medicine, Vol 11 (2024)

Subject Terms: CAR T-cell therapy, immune effector cell therapy, regulatory environment for cellular therapeutics, bispecific antibodies (BsAbs), TILs (tumor infiltrating lymphocytes), Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1462307/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/f0abd05f4a5f47ad88dca18090e29d19

Tumor microenvironment in primary central nervous system lymphoma (PCNSL)

Authors: Qiqi Jin, Haoyun Jiang, Ye Han, Litian Zhang, Cuicui Li, Yurong Zhang, Ye Chai, Pengyun Zeng, Lingling Yue, Chongyang Wu

Source: Cancer Biology & Therapy, Vol 25, Iss 1 (2024)

Subject Terms: PCNSL, TME, TILs, TAMs, MDSCs, Tregs, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1538-4047; https://doaj.org/toc/1555-8576

Access URL: https://doaj.org/article/0fac5804a2cf457e8fb147ac2456960e

The analytical and clinical validity of AI algorithms to score TILs in TNBC: can we use different machine learning models interchangeably?Research in context

Authors: Joan Martínez Vidal, Nikos Tsiknakis, Johan Staaf, Ana Bosch, Anna Ehinger, Emma Nimeus, Roberto Salgado, Yalai Bai, David L. Rimm, Johan Hartman, Balazs Acs

Source: EClinicalMedicine, Vol 78, Iss , Pp 102928- (2024)

Subject Terms: TILs, Tumor infiltrating lymphocytes, Breast cancer, Machine learning, Deep learning, Artificial intelligence, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537024005078; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/0adae23c9c8543aebbd1a78749fbdeaa

Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy

Authors: Ying Zheng, Andriana Lebid, Liam Chung, Juan Fu, Xiaoxu Wang, Andrea Otrocol, Jelani C. Zarif, Hong Yu, Nicolas J. Llosa, Drew M. Pardoll

Source: OncoImmunology, Vol 13, Iss 1 (2024)

Subject Terms: Activin, cancer immunotherapy, Foxp3, iTregs, TILs, Acvr1c, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/3c70e25a6b1c4abc8a3c38e2792d5145