PD-1 suppression enhances HIV reactivation and T-cell immunity via MAPK/NF-κB signaling

Authors: Xueru Lin, Bo Song, Lijun Cao, Lin Zhang, Siyu Liu, Xue Wang, Xiaohong Chen, Shuchen Li

Source: European Journal of Medical Research, Vol 30, Iss 1, Pp 1-10 (2025)

Subject Terms: PD-1, HIV infection, T-cell function, MAPK/NF-κB signaling pathway, Immune escape, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/452226ac46dc4937abcc3fd4cb0621b6

Comprehensive evaluation of immunological attributes and immunotherapy responses of positive T cell function regulators in colorectal cancer

Authors: Ke Pu, Jingyuan Gao, Yang Feng, Jian Hu, Shunli Tang, Guodong Yang, Chuan Xu

Source: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-20 (2024)

Subject Terms: T-cell function positive regulators, Immunotherapy, Colorectal Cancer, Tumor microenvironment, Risk score model, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/0cfad842140c46f0bcfa3d534a77cae3

Impact of Hyperferritinemia on Immune Modulation in Septic Diabetic Patients

Authors: Min-Ji Kim, Eun-Jung Choi, In-Kyu Lee

Source: Diabetology, Vol 5, Iss 3, Pp 344-355 (2024)

Subject Terms: hyperferritinemia, diabetes, sepsis, immune modulation, T cell function, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://www.mdpi.com/2673-4540/5/3/26; https://doaj.org/toc/2673-4540

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MicroRNA signatures of CD4+ T cell subsets in healthy and multiple sclerosis subjects determined by small RNA-sequencing

Authors: Culina, Slobodan ^{a, 1}, Commère, Pierre-Henri ^{b, 1}, Turc, Elodie ^{c, 1}, Jouy, Axel ^{d, g}, Pellegrini, Sandra ^e, Roux, Thomas ^f, Hasan, Milena ^a, Monot, Marc ^c, Michel, Frédérique ^{e, g, ⁎}

Source: In Journal of Neuroimmunology 15 April 2025 401

Targeting METTL3 as a checkpoint to enhance T cells for tumour immunotherapy

Authors: Kaixin Wu, Sa Li, Guangliang Hong, Hongzhi Dong, Tongke Tang, He Liu, Lingmei Jin, Siyuan Lin, Jingyun Ji, Mingli Hu, Shuntian Chen, Haoyuan Wu, Guanzheng Luo, Xiangqian Kong, Jiekai Chen, Jiangping He, Hongling Wu

Source: Clinical and Translational Medicine, Vol 14, Iss 11, Pp n/a-n/a (2024)

Subject Terms: B16 melanoma, immunotherapy, METTL3, N6‐methyladenosine (m6A), T‐cell function, YTHDF2, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/a3af5784d3174183b4c024daae7e711b

L-Arginine and immune modulation: A pharmacological perspective on inflammation and autoimmune disorders

Authors: Dimeji, Igbayilola Yusuff ^{a, ⁎}, Abass, Kasim Sakran ^b, Audu, Ngabea Murtala ^c, Ayodeji, Adekola Saheed ^d

Source: In European Journal of Pharmacology 15 June 2025 997

Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function

Authors: Abdullah Degirmencay, Sharyn Thomas, Angelika Holler, Samuel Burgess, Emma C. Morris, Hans J. Stauss

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: TCR (T-cell receptor), TCR-T therapy, CD3-zeta, T cell function, TCR mispairing, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1386132/full; https://doaj.org/toc/1664-3224

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Characterization of atypical T cells generated during ex vivo expansion process for T cell-based adoptive immunotherapy

Authors: Patricia Mercier-Letondal, Abhishek Kumar, Chrystel Marton, Francis Bonnefoy, Maxime Fredon, Laura Boullerot, Barbara Dehecq, Olivier Adotévi, Yann Godet, Jeanne Galaine

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: T cell-based adoptive cell immunotherapy, transgenic TCR T cells, CD8 and CD4 expression, MHC restriction, ex vivo T cell culture process, T cell function, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1202017/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/47c72de19c5b40c2b6c2e75433a338fb

Cycling and activated CD8+ T lymphocytes and their association with disease severity in influenza patients

Authors: Shuai Liu, Zhisheng Huang, Ruyue Fan, Ju Jia, Xiaoyan Deng, Xiaohui Zou, Hui Li, Bin Cao

Source: BMC Immunology, Vol 23, Iss 1, Pp 1-9 (2022)

Subject Terms: Severe influenza infection, T cell function, Cell cycle, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2172

Access URL: https://doaj.org/article/57cf44bd30f643fbbf837895af3aaadf

Modulation of T cell function and survival by the tumor microenvironment

Authors: Nikita Mani, Dathan Andrews, Rebecca C. Obeng

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: T cell function, immunosuppression, metabolism, tumor microenvironment, immune checkpoint, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1191774/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/72de7707fb724e4fac5604a485c98795

Modifications outside CDR1, 2 and 3 of the TCR variable β domain increase TCR expression and antigen-specific function

Authors: Abdullah Degirmencay, Sharyn Thomas, Fiyaz Mohammed, Benjamin E. Willcox, Hans J. Stauss

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: TCR-T therapy, TCR (T cell receptor), TCRV, T cell function, framework engineering, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1148890/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/245a33148092493bbaf9c3a60352e6f0

Soluble immune checkpoints as correlates for HIV persistence and T cell function in people with HIV on antiretroviral therapy

Authors: Chris Y. Chiu, Maya D. Schou, James H. McMahon, Steven G. Deeks, Rémi Fromentin, Nicolas Chomont, Michelle N. Wykes, Thomas A. Rasmussen, Sharon R. Lewin

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: HIV, soluble immune checkpoint, immunotherapy, immune checkpoint blockade, HIV reservoir, HIV-specific T-cell function, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1123342/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/64a3fccd9520467d87cf447a13d006fc

Positive regulators of T cell functions as predictors of prognosis and microenvironment characteristics of low-grade gliomas

Authors: Yang Li, Yabo Feng, Fushu Luo, Gang Peng, Yueran Li

Source: Frontiers in Immunology, Vol 13 (2023)

Subject Terms: low-grade glioma, positive regulators of T cell functions, tumor microenvironment, T cell function, immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1089792/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/697260e8252841eaaa999ceb99fc3e92

T-cell activation state differentially contributes to neuropsychiatric complications in women with HIV

Authors: Dionna W. Williams, Bianca R. Flores, Yanxun Xu, Yuezhe Wang, Danyang Yu, Brandilyn A. Peters, Adebola Adedimeji, Tracey E. Wilson, Daniel Merenstein, Phyllis C. Tien, Mardge H. Cohen, Kathleen M. Weber, Adaora A. Adimora, Igho Ofotokun, Margaret Fischl, Janet Turan, Bülent Turan, Geoffroy Laumet, Alan L. Landay, Raha M. Dastgheyb, Stephen J. Gange, Sheri D. Weiser, Leah H. Rubin

Source: Brain, Behavior, & Immunity - Health, Vol 25, Iss , Pp 100498- (2022)

Subject Terms: HIV, T-cell function, Cognition, Mental health, Women, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666354622000886; https://doaj.org/toc/2666-3546

Access URL: https://doaj.org/article/343c52777eb14015a1b0466b4d2aeebd

Relationship between T-cell-dependent and T-cell-independent vaccines after neurotrauma; is the B-cell response preserved?

Authors: Anna Ljunghill Hedberg, Karlis Pauksens, Per Enblad, Anders Larsson, Jan Sjölin

Source: Human Vaccines & Immunotherapeutics, Vol 18, Iss 5 (2022)

Subject Terms: posttraumatic meningitis, pneumococcal polysaccharide vaccine, pneumococcal conjugate vaccine, cns injury-induced immune deficiency syndrome, t-cell function, b-cell function, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/2c6162623ef8406da4f7118e60eb24c0

Signaling networks controlling ID and E protein activity in T cell differentiation and function

Authors: Sung-Min Hwang, Sin-Hyeog Im, Dipayan Rudra

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: E proteins, ID proteins, E-ID axis, T cell differentiation, T cell function, regulatory T (Treg) cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.964581/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ec9351f299624aceb15ffee91f2cc703

Immune function in newborns with in-utero exposure to anti-TNFα therapy

Authors: Batia Weiss, Shomron Ben-Horin, Atar Lev, Efrat Broide, Miri Yavzori, Adi Lahat, Uri Kopylov, Orit Picard, Rami Eliakim, Yulia Ron, Irit Avni-Biron, Anat Yerushalmy-Feler, Amit Assa, Raz Somech, Ariella Bar-Gil Shitrit

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: vaccination response, T-cell function, T-cell receptor excision circles, immunoglobulins, anti-TNFα, azathioprine, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.935034/full; https://doaj.org/toc/2296-2360

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Early Expression of Functional Markers on CD4+ T Cells Predicts Outcomes in ICU Patients With Sepsis

Authors: Jianwei Chen, Hao Wang, Ran Guo, Haolong Li, Na Cui

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: sepsis induced immunosuppression, mTOR, IFN-γ, PD-1, T-cell function, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.938538/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5598b7291dc641599c34b40e9add27f8

Diagnosis and Treatment of a Patient With Severe Combined Immunodeficiency Due to a Novel Homozygous Mutation in the IL-7Rα Chain

Authors: Rana Mansour, Yasmin El Bsat, Anthony Fadel, Youmna El-Orfali, Dolly Noun, Nidale Tarek, Nabil Kabbara, Miguel Abboud, Michel J. Massaad

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: inborn errors of immunity, severe combined immunodeficiency, IL-7Rα chain, T cell function, hematopoietic stem cell transplantation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.867837/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8e78822a8cb242409aada9a360242348

Contribution of a Novel Pertussis Toxin-Like Factor in Mediating Persistent Otitis Media

Authors: Longhuan Ma, Colleen Sedney, Yang Su, Kalyan K. Dewan, Bodo Linz, Eric T. Harvill

Source: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Subject Terms: chronic otitis media (COM), Bordetella pseudohinzii, PTx-like toxin, T cell function, middle ear, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.795230/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/2472a08460644a9aaae48326e50c58bc